EMAN RESEARCH PUBLISHING | Journal of Angiotherapy
Cancer Angiogenesis biology and therapeutics | Impact 0.16 (CiteScore) | Online ISSN  2207-872X

Journal of Angiotherapy

The Journal of Angiotherapy is an, international, peer-reviewed, Open Access journal that publishes research articles on all aspects of angiogenesis in a continuous publicat More +

Editor-in-Chief: Fazlul Huq

Journal of Angiotherapy

Volume 8 Number 2 2024

Table of Contents


Published online 05 February 2024

Vitamin D Deficiency As A Contributor To Atherosclerosis Development – A Review

Anastasia V. Poznyak 1*, Victoria A. Khotina 2, Alexandra A. Melnichenko 2, Victor Y Glanz 2, Vasily N. Sukhorukov 2, and Alexander N. Orekhov 2*

pp. 1-11

Vitamin D deficiency and cardiovascular diseases, explores role in inflammation, oxidative stress, and vascular calcification

Abstract | Full Text | PDF (900 KB) | Open Access Article

  

Published online 08 February 2024

Repurposing Drugs for Overcoming Therapy Resistance in Colon Cancer – A Review

Mahdi Darvishi 1, Amir Mohammad Chekeni 2, Mohammad Fazelhosseini 1, Zeenat Iqbal 3*, Mohd Aamir Mirza 3*, Perwez Alam 4, Ali Akhtar 4, Mohd. Aslam 5, Esra Tariq Anwer Bayrakdar 5

pp. 1-20

Oncology research seeks new therapies for aggressive CRC, utilizing repurposed drugs for accelerated and safer treatment approaches.

Abstract | Full Text | PDF (445 KB) | Open Access Article

  

Published online 09 February 2024

A Review of 3d Printing Model of New Blood Vessel Formation For Pharmaceutical Applications

Nidhi Mishra 1*, Priya Vij 1, Akanksha Mishra 1

pp. 1-6

Innovative synthetic blood vessels offer promising solutions for cardiovascular diseases, providing safer, more accessible treatments for aging populations

Abstract | Full Text | PDF (535 KB) | Open Access Article

  

Published online 09 February 2024

Efficient Removal of Acetamiprid Pesticide Using Date Core-Derived Activated Carbon and Korai Clay As A Good Sorbent

Huda Azhar Fadel 1*,  Lekaa Hussein Khdaim 1

pp. 1-9

Iraqi date core-derived activated carbon effectively removes acetamiprid pesticide, crucial for combating water pollution, supported by comprehensive adsorption studies.

Abstract | Full Text | Open Access Article

  

Published online 12 February 2024

A Double-blind, Randomized Clinical Trial Study of Plantago major l. Syrup on Menorrhagia

Sajedeh Ghasempour 1, Mohsen Naseri 2, Fatemeh Alijaniha 2, Yasin Karimi 3, Anoushirvan Kazemnejad 4, Shahrzad Hadavand 5 , Seyedeh Fatemeh Jafari 2

pp. 1-8

The study highlights Plantago major's potential to reduce menorrhagia severity and duration, offering a promising complementary treatment with minimal side effects.

Abstract | Full Text | PDF (329 KB) | Open Access Article

  

Published online 13 February 2024

Understanding and Combatting COVID-19: Insights from Clinical Characteristics and Management Strategies

Bala Krishnan A 1, Vigneshwaran V 1, Tharani Kumar L 1, M. Shagar Banu 1

pp. 1-6

Timely analysis is crucial for understanding and combating global health crises like COVID-19 effectively

Abstract | Full Text | Open Access Article

  

Published online 13 February 2024

Concerning Fungal Coinfections in COVID-19: Risks, Types, and Prevention – A Review

Bala Krishnan A  1, Vinoth Kumar K K 1, Tharani Kumar L 1, M. Shajini G Inbakani 1

pp. 1-7

The review highlights the alarming rise of fungal infections like Mucormycosis among COVID-19 patients, necessitating prompt diagnosis and care to prevent fatalities.

Abstract | Full Text | Open Access Article

  

Published online 13 February 2024

Unprecedented Rise of Mucormycosis in COVID-19 Patients: Urgent Need for Protocol Adaptation and Awareness in India – A Review

Nithya A 1, Vinoth S V 1, Ashok Kumar M 1, Sindhu T 1

pp. 1-6

Mucormycosis in COVID-19 patients in India necessitates urgent updates in treatment protocols and public awareness

Abstract | Full Text | Open Access Article

  

Published online 14 February 2024

Navigating COVID-19 Treatment: CT Scans, Steroids, and Medical Practice Challenges in India

Jayanthi E 1, C. Elayaraja 2, Priyadharshini S 2, Ashok kumar M 2

pp. 1-6

The review highlights India's struggle with COVID-19, emphasizing the need for tailored treatments amid rising cases, cautioning against unnecessary tests and misuse of medications.

Abstract | Full Text | Open Access Article

  

Published online 14 February 2024

In vitro Cytotoxicity and Apoptotic Activity of Aquous, Chloroform and Methanol Extracts of Kiwi Fruit Actinidia deliciosa in MCF-7 cells

Kartheeswari 1, Archana C 1, Anupreyaa K 1, Saranya M 2

pp. 1-5

Assessment of A. deliciosa extracts' anticancer potential on MCF-7 cells offers insights for natural cancer medication development

Abstract | Full Text | Open Access Article

  

Published online 15 February 2024

Impact of Dapagliflozin on Atherosclerosis through Inflammation and Oxidative Pathways

Zainab Abdlkadhim Aboshnin 1*, Safa Azhar Razzaq 1, Zahraa Ibraheim Jawad Shubber 2

pp. 1-8

Atherosclerotic patients need therapies targeting inflammation and oxidation. This study supports Dapagliflozin's use for clinical benefits in atherosclerosis.

Abstract | Full Text | Open Access Article

  

Published online 15 February 2024

Association Between Low Bone Mineral Density in Hemophilia Patients and Musculoskeletal Function Impairments

Rasha Ibrahim Salman 1* , Khalid Mahdi Salih 1*, Nidal Karim Al-Rahal 2*

pp. 1-8

Hemophilia patients with low bone density (BMD) face higher risk with severe limitation of movement (LOM) and viral infections.

Abstract | Full Text | PDF (923 KB) | Open Access Article

  

Published online 16 February 2024

The Analysis of Hypertension Knowledge in Adults in Telafer City: Implications for Health Education and Intervention

 Mohammed Qassim Baktash 1* , Ali Ismael Sulaiman 1

pp. 1-6

Understanding hypertension in Telafer City adults is vital for preventing problems, guiding interventions, and managing the disease effectively

Abstract | Full Text | Open Access Article

  

Published online 17 February 2024

The Analysis of Hematological Parameters CBC, ABO, NLR, and APTT and Its Implications on Haemophilic Patients with Low Bone Mineral Density

Rasha Ibrahim Salman 1* , Khalid Mahdi Salih 1, Nidal Karim Al-Rahal 2

pp. 1-8

The study determined a high prevalence of low bone mineral density in hemophilic patients, associated with elevated NLR and prolonged APTT.

Abstract | Full Text | Open Access Article

  

Published online 17 February 2024

Efficacy of Paromomycin-Conjugated Nano Chitosan in Treating Entamoeba histolytica Infection in Mice

Hajar Falih Hishan Aldali 1*, Shatha Khudiar Abbas 1, Ahmed Naji Abd 1

pp. 1-7

Entamoeba histolytica causes widespread amebiasis. Chitosan-paromomycin nanoconjugates effectively treated infected mice, reducing liver enzyme levels, showing promising therapeutic potential.

Abstract | Full Text | Open Access Article

  

Published online 17 February 2024

Anti-Cancer Activity of Allium Ascalonicum Ethanol Extract Against Human Hepatocellular Carcinoma Cell Line (HepG-2)

Geetha N B 1*, Chintala Venkatesh 1, Suresh M 1, Manikandan S 2

pp. 1-6

Allium ascalonicum might be a safer, more effective alternative to toxic chemotherapy for combating cancer with targeted potency.

Abstract | Full Text | Open Access Article

  

Published online 18 February 2024

In vitro Anti-cancer Activity of Methanol Extracts of Kiwi Fruit, Actinidia deliciosa in HCT-119 Cells

Geetha N B 1, Priya R 1, Weslin D 1, Ashmi Christus A T 2

pp. 1-5

The study of anti-cancer properties of Actinidia deliciosa methanol extract in Colorectal cancer as effective treatments.

Abstract | Full Text | Open Access Article

  

Published online 18 February 2024

Green Fungus Challenges in Post-COVID Health Landscape

Jeha J 1, Sudha S 1, Geetha N B 1, Benitta Sherine S 2

pp. 1-5

This review provides Green Fungus challenge in post-COVID situation. Early detection, hygiene, and research are imperative.

Abstract | Full Text | Open Access Article

  

Published online 18 February 2024

Diagnosis of Chronic Brucellosis with Interferon-Gamma Quantification

Sarah Yahya Abdullah 1, Yasir Mufeed Abdulateef 2*, Sawsan Qahtan Taha Al-Quhli 3

pp. 1-6

This study showed the improvement of brucellosis diagnosis using interferon-gamma for better detection in chronic cases

Abstract | Full Text | Open Access Article

  

Published online 19 February 2024

Epidemiological Analysis of Hepatitis B and C Viruses in Fallujah for Health Intervention and Disease Control

Ahmed Saadi khlaf 1*, Asif Hasan Abdulrazaq 2, Nawar Bahaa Abdulsahib 3, Manaf Akram Ismaell 3, Mustafa Asif Hasan 3

pp. 1-8

Investigating Hepatitis B and C in Fallujah revealed higher prevalence among males, aiding targeted interventions and public health initiatives.

Abstract | Full Text | Open Access Article

  

Published online 19 February 2024

A study of Enhancing Fencing Skills with The Impact of Special Exercises on Kinetic Response and Attack Accuracy among Young Foil Players

Reem Mohammed Abdel Wahhab 1*

pp. 1-7

This study showed an improved exercise enhancing kinetic response, vital for fencing to optimize athletes' and their healthy performance.

Abstract | Full Text | Open Access Article

  

Published online 19 February 2024

Determination of Demographic Liver Health with Giardia lambila Infection Analysis in Diyala

Noora Dhyaaldain Abed 1*, Shahad Abdul Jabbar Mohammed 2*

pp. 1-6

This study analyzed the Giardia infection as early detection for liver health intervention.

Abstract | Full Text | Open Access Article

  

Published online 20 February 2024

Salmonella Biofilms And Antibiotic Resistance Determination From Different Patient Types

Mariam Ayad Abd 1*, Sawsan Q. T. Al-Quhli 2, Mahir Ali Jassim 3

pp. 1-8

This study discussed important information about antibiotic resistance and how harmful Salmonella bacteria are in Iraqi patients, helping to plan better public health measures.

Abstract | Full Text | Open Access Article

  

Published online 20 February 2024

Cumin Extract Alters The Histology of Kidney and Duodenum in Adult Rabbit

Hussein B. Mahmood 1*,  Naseer  A. Al-Arubaye 1, Walaa F. Obead 1

pp. 1-6

This study showed the histological alterations of the kidney and duodenum due to excessive use of cumin.

Abstract | Full Text | Open Access Article

  

Published online 20 February 2024

Treatment of High-Fat Diet-Induced Obesity and Insulin Resistance Using Rose Flowers (Rosa damascena) in Rat

Kamran Javed Naquvi 1*, Javed Ahamad 1

pp. 1-6

Rosa damascena petals reduce obesity-related markers and insulin resistance. This is a natural agent for metabolic health improvement and weight management.

Abstract | Full Text | Open Access Article

  

The peer-reviewed and edited version of record published online before inclusion in an issue

Published online 08 June 2018

Angiogenic Switches Play a Critical Progression in Cancer

Nozlena A Samad a*, Ahmad Bustamam Abdul b, Rasedee Abdullah b, Heshu Rahman b,d,e KZ Khor a, Max Stanley Chartrand  c

The role of angiogenesis in tumor development and operating this very particular switch in controlling tumor.    

Abstract | Full Text | PDF (1 MB) Open Access Article

  

Published online 10 August 2018

Evaluation of antioxidant, antiangiogenic and antitumor properties of Anogeissus leiocarpus against colon cancer

Loiy Elsir Ahmed Hassan a, b*, Foud S. Al-Suade a,  Samah M.Fadul c, Amin Malik Shah Abdul Majid a

Anogeissus leiocarpus is a traditional medicinal plant, used to treat diarrhea, fever, coughs, rheumatism, leprosy, wounds and skin diseases and psoriasis. This study was aimed to investigate the antiangiogenic and cytotoxic effects of six extracts from Anogeissus leiocarpus (leaves and bark).

Abstract | Full Text | PDF (2 MB) Open Access Article

  

Published online 16 August 2018

Targeting inducible Nitric Oxide Synthase (iNOS) in the prevention of vascular damage and cardiac inflammation in CVD

Nafees Uddin Chowdhurya, Abida Tishab, Juthika Sarkerb, Pulak Dev Nathb, Nowshin Ahmedb, Shahanshah Abdullahb, Tasdik Farooqb, Waich Mahmudb, Md. Mohabbulla Mohibb,c, Md. Abu Taher Sagorb

The molecular mechanism of iNOS that leads to CVD is comprehensively summarized in this review so as to aid in drug discovery strategies for the treatment of CVD.

Abstract | Full Text | PDF (3 MB) Open Access Article

  

Published online 07 January 2019

Modes of Anti-angiogenesis in Chemical Perspectives

Shan Arif a, b, Muhammad Imran a, b, Muhammad Adnan Iqbal a, b

In the current study, role of synthesized chemical pharmacores like Humulus lupulus, Hypericum perforatum, Panax ginseng, Coptis chinensis and Rheum palmatum (Varinska et al., 2010) as anti-angiogenesis has been compiled. 

Abstract | Full Text | PDF (3 MB) Open Access Article

  

Published online 04 February 2019

Ethosomal formulation composed of standardized Orthosiphon stamineus extract and sophorolipid inhibits angiogenesis of melanoma in vivo

Mansoureh Nazari Vishkaei a, Mohamed Khadeer Ahamed Basheer c, Amin Malik Shah Abdul Majid a,b

SLOS vesicles can be considered for effective dermal therapeutic agent for the treatment of skin cancer.

Abstract | Full Text | PDF (1 MB) Open Access Article

  

Published online 11 May 2019

Anti-GBM potential of Rosmarinic acid and its synthetic derivatives via targeting IL17A mediated angiogenesis pathway

Md Shamsuddin Sultan Khan A,C,E, Mohammad Adnan Iqbal B, Muhammad Asif A, Tabinda Azam B, Majed Al-Mansoub A, Rosenani S. M. A. Haque B, Mohammed Khadeer Ahamed Basheer C, Aman Shah Abdul Majid D, Amin Malik Shah Abdul Majid A,C,E*

Metal salts and base rosmarinates demonstrated potent anti-GBM efficacy as IL17A inhibitor with minimal toxicity.   

Abstract | Full Text | PDF (1 MB) Open Access Article | Supplementary Material

  

Published online 15 May 2019

Ascorbate blocks acetylcholine- and bradykinin-induced vasodilatation in retinal vascular bed of the bovine isolated perfused eye

Li-xin XU A, Xiao-bo XIA B, Aman Shah Abdul Majid C, Dan Ji B

This study provides insight to EDHF-mediated vasomotor response, as well as various eye disorders caused by dysfunctional retinal arteries, like central retinal artery occlusion.

Abstract | Full Text | PDF (971 KB) Open Access Article

  

Published online 24 June 2019

Evaluation of Safety and Efficacy of Labeesity® for Weight Management and Fatigue in an Obese Female Patient with Hypothyroidism: A Case Report

Aman Shah Abdul MajidA*, Elham FarsiB, Natesan VijayalakshmiC, Syarifah Aisya Syed AmranD, Mahibub Mahadmadsa KanakalE, Zarina Thasneem ZainudeenF*

Labisia pumila extracts based products will require robust studies to be conducted utilizing larger patient numbers and over extended periods of time to rule out any potential toxic effects.

Abstract | Full Text | PDF (769 KB) Open Access Article

  

Published online 03 November 2019

Extract of Urgenia grandiflora inhibited breast cancer cell (MCF-7) proliferation and tumorgenesity

Ibrahim B. E. El Bashir A,B, Loiy Elsir Ahmed HassanC, Amin M. S. Abdul Majid D, Sakina Yagi A*

U. grandiflora could be a new source of chemotherapeutic for breast cancer.

Abstract | Full Text | PDF (3 MB) Open Access Article

  

Published online 30 December 2019

Acute and Sub- chronic Toxicity Study of Encapsulation of Combine Plants Extract of Ficus deltoidea and Gynocthodes sublanceolata in Balb/c Mice Model

Rafida Kh. Ahmed A, M. Syarhabilahmad A, Midhat Nabil A, Fouad Saleih R. Al –Suede B,*

Oral treatment with encapsulated plant extract Ficus deltoidea and Gynocthodes sublanceolata did not appear adverse side effect and it is safe to use for therapeutic purposes.

Abstract | Full Text | PDF (852 KB) Open Access Article

  

Published online 08 July 2020

Phytochemicals in Cancer with Special Emphasis on Ovarian Cancer

Meher U Nessa1,2, Md S Anwar1, Fazlul Huq3*

Reviews current literature on use of phytochemicals in prevention and therapy of ovarian cancer including mechanism of action.

Abstract | Full Text | PDF (1 MB) Open Access Article | Supplementary Material

  

Published online 12 September 2020

Dose Dependent Synergism from Combination of Platinum Drugs with Curcumin against Colorectal Cancer Cell Lines

Hana Bali1, Jun Qing Yu1, Philip Beale2, and Fazlul Huq3

Ox in combination Cur demonstrated very high synergism against HT-29 and Caco-2 cell lines.

Abstract | Full Text | PDF (1002 KB) Open Access Article

  

Published online 13 March 2021

Immunomodulatory and Antiangiogenic Mechanisms of Polymolecular Botanical Drug Extract C5OSEW5050ESA OS Derived from Orthosiphon stamineus

Fouad Saleih R. Al-Suede1*, Mohamed B. Khadeer Ahamed1, Aman S. Abdul MajidSultan Ayesh Mohammed Saghir3, Chern E. Oon4, Amin Malik Shah Abdul Majid1,5*

C5OSEW5050ESA OS strongly curbs variety of angiogenesis modulators in vitro, ex vivo and in vivo.

Abstract | Full Text | PDF (1 MB) Open Access Article

  

Published online 30 October 2021

Cannabis Sativa: A Remedy for Convulsion by Inhibition of GABAA Receptor and Significantly Delayed Onset of Seizure Latency and Death - An Experimental Validation and Molecular Docking

Ben Enoluomen Ehigiator1, SamuelKelechi Mobisson2, Iheanyichukwu Wopara3*, Chinonye Cynthia Chibuife1, Uwaezuoke Chukwuekele Awarajih3, Harrison Ogheneochuko Eruotor3

Abstract | Full Text | PDF (521 KB) Open Access Article

  

Published online 10 November 2021

Immunomodulatory Effect of Tinospora cordifolia with Special Reference to Suppression of Cytokine Storm Induced in SARS-CoV-2

Aishath Thahuseen Waheed1, Thurga Ayavoo2,3, Karthikeyan Murugesan2,3,  Fouad Saleih R. AL-Suede4,5, Ashok Gnanasekaran2,3*

Development of anti-inflammatory herbal drug.

Abstract | Full Text | PDF (464 KB) Open Access Article

  

Published online 11 November 2021

Phytochemicals with Direct and/or Indirect Anti-angiogenic Properties Against Various Cancer Types Focusing on Their Mechanism of Action

Ibrahim Al-deeb1,2,3, Julia Joseph1, Amin Malik Shah Abdul Majid2, Nozlena Abdul Samad1

Abstract | Full Text | PDF (289 KB) Open Access Article

  

Published online 02 February 2022

Evaluation on Antibacterial Activity and Hepatoprotectivity of Rauwolfia serpentina

Gnanasekaran Ashok1,6*, Yukshna A/P Ramunaidu2, Fouad saleih R.AL-Suede3,4 Murugesan Karthikeyan1, Pugazhandhi Bakthavatchalam5, Sajeewa P.  Rathnayake6

The results of this study provide scientific evaluation of antibacterial activity and hepatoprotective effect of Rauwolfia serpentina which will be useful to researchers investigating the compounds with this potential and encouraging the development of new findings in this field.

Abstract | Full Text | PDF (556 KB) Open Access Article

  

Published online 04 March 2022

A Systematic Review on Temporal Lobe Epilepsy Patients with Corona Virus Infection

Pugazhandhi Bakthavatchalam1, Fouad Saleih R.AL-Suede2,3, Sudarshan S.1*

Abstract | Full Text | PDF (197 KB) Open Access Article

  

Published online 04 April 2022

Comparison of anti-inflammatory and analgesic effects of artocarpin-rich Artocarpus heterophyllus extract and artocarpin

Rizwan Rashid Bazmi1, Muhammad Asif2**, Hafiza Sidra Yaseen3, Pharkphoom Panichayupakaranant1,4*

The present study has an impact on overcoming the inflammation problem, which can lead to various types of chronic inflammatory diseases, using the artocarpin  & artocarpin-rich Artocarpus heterophyllus extract. The primary significance of this research is the achievement of preparation of a natural anti-inflammatory and analgesic agent using a green chemistry, which contributes to combat inflammation and analgesia. Furthermore, this method is practically used for industrial commercialization.    

Abstract | Full Text | PDF (909 KB) Open Access Article

  

Published online 20 April 2022

Anti-tumor Activity of NuvastaticTM (C5OSEW5050ESA) of Orthosiphon stamineus and Rosmarinic Acid in An Athymic Nude Mice Model of Breast Cancer

Ashwaq Hamid Salem Yehyaa,*, Majed Ahmed Al-Mansoubb, Fouad Saleih Resq Al-Suedea, Siti Balkees Binti STN Hameed Sultana, Muhammad Asyraf Abduramana, Noor Amanina Azmic, Mufda jameel abedalhadi alrawashdehd, Seyedeh Fatemeh Jafarie, Amin Malik Shah Abdul Majida,f

Abstract | Full Text | PDF (1015 KB) Open Access Article

  

Published online 02 July 2022

Therapeutic Targeting on Death Pathways in Glioblastoma

Pavithra Suppiah1, Julia Joseph1, Rolla Al-Shalabi1, Nik Nur Syazni Nik Mohamed kamal1, Nozlena Abdul Samad1*

Abstract | Full Text | PDF (311 KB) Open Access Article

  

Published online 24 August 2022

Hepatoprotective effect of Hydro-alcohol extract of Mimusops elengi root against antitubercular drug-induced hepatotoxicity in rats

Prakash Dabadi1, Fouad Saleih Resq AL-Suede2,3*, Chandrashekhar VM4*, Mallappa Shalavadi 4 , Ashok Gnanasekaran5

Development of therapeutics for the treatment of hepatotoxicity and oxidative stress  induced by ATDs

Abstract | Full Text | PDF (589 KB) Open Access Article

  

Published online 17 September 2022

Targeting Microtubules by Phytoestrogens for the Treatment of Cancer: An Overview

Fan Xu1, Nozlena Abdul Samad1, Nurhuda Mohamad Ansor1*

In this review, we summarize reported effects of some phytoestrogens that bind directly to tubulin at various binding site and disrupt the microtubule dynamics, either by promoting microtubule polymerization or enhancing microtubule depolymerization.

Abstract | Full Text | PDF (737 KB) Open Access Article

  

Published online 25 September 2022

Environmental and physiological angiogenesis in causing CVD with oxidative pattern

Md. Fakruddin1*, Md. Asaduzzaman Shishir2, Kumkum Rahman Mouree2, Shamsuddin Sultan Khan3

Oxidative stress plays critical role in angiogenesis and cardiovascular disease progression. Drugs targeting oxidative stress might provide a new treatment paradigm for related disorders.

Abstract | Full Text | PDF (1 MB) Open Access Article

  

Published online 04 October 2022

Ferritin and High Sensitivity C-Reactive Protein (hs-CRP) may predict the COVID-19 patient’s fate

Zahra A. Kheudhier1*, Alaa K. Mossa2

Circulating biomarkers are an essential predictor for the prognosis of COVID-19-infected patients as they represent the severity of inflammation and immune status.

Abstract | Full Text | PDF (1 MB) Open Access Article

  

Published online 04 November 2022

Prognostic Factors and Predictors of Mortality in Patients with Critical Limb Ischemia: A Current Clinical Perspective

Moniruddin Chowdhury1,2, Syeda Humayra2, Sohel Mahmud3, Yukihito Higashi4, YD Singh1

PAD and its impact in physical impairment or mortality.

Abstract | Full Text | PDF (201 KB) Open Access Article

  

Published online 15 November 2022

Efficacy of Herbal Medicine as Adjunctive Therapy for Skin Cancer

Norbayu Mansor1, Julia Joseph1, Rola Al Shalabi1, Nozlena Binti Abdul Samad*1

Phytochemicals can be used for skin cancer prevention and treatment.

Abstract | Full Text | PDF (373 KB) Open Access Article

  

Published online 22 November 2022

Immunoglobulin G Seroprevalence of Lassa Fever Virus Among Individuals Residing Along the Banks of River Niger in Anambra State, Nigeria.

Umezurike Kingsley Chimuanya1, Chukwuma Oluchukwu Mariagoretti1,2, Ochiabuto Mary Barbara1, Manafa Patrick Onochie1, Ntum Ifeanyichukwu Michael1, Chukwuma George Okechukwu1,2

LF-specific IgG seroprevalence among inhabitants of river banks in Anambra State, Nigeria

Abstract | Full Text | PDF (292 KB) Open Access Article

  


Published online 24 December 2022

Cancer Immunotherapy in 2022 - End of the Beginning

Assoc. Prof. Dr. Toh Han Chong

Abstract | Full Text

  



Published online 24 December 2022

Precision Medicine in Lymphoid Malignancies

Prof. Dr. Richard Rosenquist Brandell

Abstract | Full Text

  




Published online 24 December 2022

Updates on Treatment of Gastroesophageal Cancers

Prof. Dr. Ho Gwo Fuang

Abstract | Full Text

  

Published online 24 December 2022

Insights into Advanced Non-Small Cell Lung Cancer Patients with MET Alterations

Emeritus Prof. Dr. Liam Chong Kin

Abstract | Full Text

  





Published online 24 December 2022

Targeted Delivery of Cisplatin Using RGD-Modified ZIF-90 as Delivery Vehicle

Emilia Abdulmalek1,2,*, Adamu Abubakar1,3, Kyle. E. Cordova4, Mohd Basyaruddin Abdul Rahman1,2,5

Abstract | Full Text

  


Published online 24 December 2022

Molecular Modelling Analysis of Squamocin as Potential BCL-XL Anti-apoptotic Protein Inhibitor

Kaynat Khimani1, Mohd Faiz Abdul Ghani1,2, Rozana Othman3, Noraziah Nordin1,*

Abstract | Full Text

  

Published online 24 December 2022

Differential Cell Cycle Arrest in Dihydroorotate Dehydrogenase (DHODH) Inhibition of Different Subtypes of Breast Cancer Cell Lines 

Muhammad Aiman Akmal Shahhiran1,2, Mohamad Fairus Abdul Kadir3, Nurshamimi Nor Rashid1,2, Shatrah Othman1,2,* 

Abstract | Full Text

  

Published online 14 May 2023

Investigation Of Anti-Tumour Activity Of Orthosiphon Stamineus On Human Oral Squamous Cell Carcinoma

Shah kamal Bin Jamal Dina, Fouad Saleih Resq Al-Suedeb,c*,Farahnaz Aminid, Aman Shah Abdul Majide, JackTan Chun Keatd, Amin Malik Shah Abdul Majidf .

The potential of Nuvastatic in the treatment of oral squamous cell carcinoma.

Abstract | Full Text | PDF (602 KB) Open Access Article

  

Published online 07 July 2023

Use of Neutralizing Monoclonal Antibodies and Its Outcome Measures in COVID-19 Patients

Moniruddin Chowdhury1,2, Syeda Humayra2, Taha Sulayman3, Keichiro Mihara4, P.K. Rajesh1

The use of monoclonal antibodies in Covid-19.

Abstract | Full Text | PDF (214 KB) Open Access Article

  

Published online 23 July 2023

Diagnostic and differential efficacy of cyclin D1 and CA15-3 in breast cancer and benign breast tumors

Anmar R. Raheem1,2, Omar F. Abdul-Rasheed1*, Omar S. Khattab3, Ahmed Z. Abdulhameed4, Hussein A. Abid1,5*

Abstract | Full Text | PDF (385 KB) Open Access Article

  

Published online 29 July 2023

Design, Synthesis, And Characterization Of New Schiff Bases For 3-Amino-1,2,4-Triazole-5-Thiolate Salt, Bearing Morpholine Ring And Biological Evaluation As Antibacterial Agents

Abeer Hussein Alia, and Mukhlif Mohsin Slaihimb*.

Antibacterial efficacy of new chemical compounds named benzaldehyde derivatives.

Abstract | Full Text | PDF (532 KB) Open Access Article

  

Published online 12 August 2023

A review of the effects of Calophyllum spp. on cancer cells

Melissa Kilus1, Nozlena Abdul Samad1*, Shaari Daud2

Abstract | Full Text | PDF (225 KB) Open Access Article

  

Published online 09 September 2023

Moringa oleifera's Effect on Colorectal Cancer

Rolla Al-Shalabi 1,2, Nozlena abdul samad 1*, Lim Vuanghao 1, Ibrahim Al Deeb 2, Julia Joseph 1

The therapeutic benefit of Moringa plant in cancer treatment

Abstract | Full Text | PDF (2 MB) Open Access Article

  

Published online 03 October 2023

Unlocking Nature’s Treasure Trove: Exploring Microorganisms for Novel Bioactives

Tasbir Amin1, Abu Bakar Karim1, Israk Iram Oyshe1, Amana Hossain1, Tafsir karim1, Jinath Sultana Jime1, Nayeema Bulbul1, Md. Asaduzzaman Shishir2, Ashrafus Safa3, Md. Fakruddin1*

Abstract | Full Text | PDF (299 KB) Open Access Article | Supplementary Material

  

Published online 16 October 2023

Optimizing The Protocol For Extraction Of Bioactive Components From Hibiscus Sabdariffa With Potent Antioxidant Activity

Nur Royhaila Mohamad *1, Farrah Payyadhah Borhan 2, Mohd Shahrizi Razali 3, Roswanira Abdul Wahab 4

Utilize statistical methods to determine which different variables impact the response to the extraction of roselle.

Abstract | Full Text | PDF (514 KB) Open Access Article

  

Published online 21 October 2023

Antioxidant Potential of Calophyllum gracilentum: A Study on Total Phenolic Content, Total Flavonoid Content, and Free Radical Scavenging Activities

Nurr Maria Ulfa Seruji1, Vivien Jong Yi Mian1*, Nor Hisam Zamakshari2, Thiruventhan Karunakaran3, Lee Feng Koo4, Wong Tze Jin4, Chan Thye Huat5

Study of potential Therapeutic activity of Calophyllum herb.

Abstract | Full Text | PDF (444 KB) Open Access Article

  

Published online 22 October 2023

The way of cholesterol in atherogenesis: from the main enemy to complex biomarkers

Anastasia V. Poznyak 1*, Victoria A. Khotina 2, Mikhail A. Popov 3, Alexander D. Zhuravlev 2, Vasily N. Sukhorukov 2, Alexander N. Orekhov 2*

Abstract | Full Text | PDF (998 KB) Open Access Article

  

Published online 02 November 2023

Knowledge and Self-Management Practice Among Diabetic Patients from the Urban Areas in Bangladesh

Md. Jubayer Hossain1, Syeda Tasneem Towhid1,2* , Sumona Akter1 , Muhibullah Shahjahan1, Tilottoma Roy1, Bithi Akter1, Tanjum Ahmed Nodee1

Abstract | Full Text | PDF (481 KB) Open Access Article

  

Published online 11 November 2023

Inhibitory Activity of Enzyme Α-Glucosidase Ethanol Extract Combination Of Mareme Plant (Glochidion arborescens (Müll. Arg.) Boerl.) Leaves And  Sala Plant (Cynometra ramiflora Linn) Leaves

Haryoto1*, Alysa Vivi Arnida1, Peni Indrayudha1, Cita Hanif Muflihah1, Khong Heng Yen2

Mareme and Sala leaves mix may be a strong blood sugar blocker, but it contains useful chemicals for potential medical research.

Abstract | Full Text | PDF (318 KB) Open Access Article

  

Published online 12 November 2023

Stromal Interaction Molecule-1 (STIM1): Orchestrating Calcium Signaling in Cancer and Hematologic Malignancies

Rabiatul Basria S. M. N. Mydin1, Adam Azlan1, Eman Salem Saeed Algariri,1 Nur Azuar Abdul Rahim2,3, Emmanuel Jairaj Moses1, Narazah Mohd Yusoff1

Abstract | PDF - $50.00 (199 KB) Buy Now

  

Published online 14 November 2023

Antiangiogenic and Anticancer Potential of Supercritical Fluid Extracts from Nutmeg Seeds; In vitro, Ex vivo and In silico studies

Sawsan S. Al-Rawi1*, Ahmad Hamdy Ibrahim2, Marthad A. Hamde3, Dinesh Babu4, Mansoureh Nazari5, Mohd Omar Ab Kadir6, Aman Shah Abdul Majid7, Amin Malik Shah8

Abstract | Full Text | PDF (2 MB) Open Access Article

  

Published online 23 November 2023

Comparative Analysis of Epstein-Barr Virus EBNA-2 Sequence Variation in Nasopharyngeal Carcinoma and Other EBV-Related Tumors

Lee Wei Zheng1,2, Rabiatul Basria S. M. N. Mydin1*, Adam Azlan1,5 and Muhamad Yusri Musa3,4

Abstract | Full Text | PDF (389 KB) Open Access Article

  

Published online 24 November 2023

Hepatitis C and Atherosclerosis: Inflammatory Interplay

Anastasia V. Poznyak 1*, Ludmila V Nedosugova 2, Vasily N. Sukhorukov 3, Alexandra A. Melnichenko 3, Elizaveta M. Pleshko 3 and Alexander N. Orekhov 3

A review of the relationship between HCV infection, inflammation, and cardiovascular pathologies.

Abstract | Full Text | PDF (709 KB) Open Access Article

  

Published online 24 November 2023

Effect of Plumbago zeylanica on Analgesia and Arthritis

Subasini Uthirapathy1*

The inhibition activity of PZ on carrageenan-induced arthritis, humoral and cellular immunity, and pain and inflammation.

Abstract | Full Text | PDF (225 KB) Open Access Article

  

Published online 27 November 2023

Pomegranate Juice Attenuates Anti-ulcer in Indomethacin-induced Peptic Ulcer

Ali Omar Yaseen 1, Payam Jamal Muhamed 1, Hacer Haltas 1 , Subasini Uthirapathy 1*

Study on using pomegranate juice supplements to treat ulcers caused by pain medications.

Abstract | Full Text | PDF (489 KB) Open Access Article

  

Published online 27 November 2023

Characterization of Essential Oil Composition of Syzygium aromaticum Linn. (Clove) by GC-MS and Evaluation of its Antioxidant Activity

Javed Ahamad 1*

The study of Clove essential oil as an antioxidant drug.

Abstract | Full Text | PDF (472 KB) Open Access Article

  

Published online 05 December 2023

Gymnemagenin a Promising Drug Candidate for Management of Hyperglycemia: In-Vitro and In-Vivo Study

Javed Ahamad1, Saima Amin2, Kamran J Naquvi1, Showkat R Mir3*

Study of Gymnema sylvestre plant for the treatment and management of diabetes.

Abstract | Full Text | PDF (1 MB) Open Access Article

  

Published online 08 December 2023

Current Perspective on Pesticides: Their Classification, Behaviour, Potential Use and Toxic Effects

Adil Ahamad1*, Javed Ahamad2, Mohd. Javed Naim2

Monitoring the use of pesticide and analyzing their acceptable levels for human health.

Abstract | Full Text | PDF (442 KB) Open Access Article

  

Published online 04 December 2023

Drug Repositioning and Response Detection Based on Randomized Control Trials for Cancer Treatment - A Review

Aman Chandrakar 1, Chetan Kumar Sonkar 2

The cancer treatment will be accelerated through drug repositioning.

Abstract | Full Text | PDF (1 MB) Open Access Article

  

Published online 01 January 2024

Black Soldier Fly Larvae Feed with Fermented Bamboo Culms Enriched with Lactic Acid Bacteria

Nurul Azila Abdul Razak 1, Ang Chung Huap 1*, Vivien Jong Yi Mian 1, Siti Nor Ain Seri Masran 2

The study of plant-based protein source as  the nutrition of Black soldier fly

Abstract | Full Text | PDF (758 KB) Open Access Article

  

Published online 05 December 2023

A Review of Potential Roles for Micro RNAs as Drugs Sensitivity Biomarkers in Breast Cancer

Monika Barsagade 1*, Ravi kishore Agrawal 2*

The role of miR-202's in discovering biomarkers for early diagnosis and improving therapeutic strategies for breast cancer.

Abstract | Full Text | PDF (393 KB) Open Access Article

  

Published online 06 December 2023

Evaluation of Cardiac Reserve Using Echocardiography for The Detection of Mild Cardiac Dysfunction in Mice - A Review

Sanjay Kumar Mire 1, Deepak Kumar Sahu 2

Echocardiography-based strain imaging offers early detection of cardiac abnormalities, treatment, and research strategy. 

Abstract | Full Text | PDF (951 KB) Open Access Article

  

Published online 06 January 2024

Determination of Active Biomarkers and the Antioxidant and Antibacterial Potential of Standardized Zygophyllum spp Extract

Mostafa Alamholo 1

Identification of active compounds in medicinal plants to control resistant bacteria

Abstract | Full Text | PDF (434 KB) Open Access Article

  

Published online 07 January 2024

Evolution of Genes and Transcripts Modifies Drug Sensitivity in Cancer Cell Lines - A Review

Krishna Sahu 1, Urvashi Jain 2

Dynamic genomic and transcriptomic evolutionary modeling guides cancer genetics, transforming treatment by predicting drug sensitivity in genomics.

Abstract | Full Text | PDF (196 KB) Open Access Article

  

Published online 07 December 2023

Discovering Novel and Old Drug Targets in Oral Cancer Stem Cells Using bio-inspired methods - A Review

Vijay Kumar Jaiswal 1, Mahendra Kumar Verma 2

Evolutionary Computation Network for Drug Repositioning reveals oral cancer stem cells, informing targeted therapies for treatment.

Abstract | Full Text | PDF (1 MB) Open Access Article

  

Published online 07 December 2023

Impedimetric Sensor Aided by Polydopamine Nanoparticles for Label-Free Detection of Breast Cancer Cells - A Review

Bhuneshwari Dewangan 1, Naina Bhoyar 2

 

A review of polydopamine sensor in breast cancer diagnosis.

Abstract | Full Text | PDF (882 KB) Open Access Article

  

Published online 08 December 2023

Analyzing The Risks, Benefits, and Therapeutic Potential of Cannabis And Cannabinoids in Tumor Therapy - A Review

Poorti Sharma 1*, Lukeshwari Sahu 1

Study explores Cannabis use by metastatic tumor patients, analyzing active components, addressing gaps in research, and promoting informed medical guidance.

Abstract | Full Text | PDF (769 KB) Open Access Article

  

Published online 08 December 2023

Review on Health And Quality of Life of Elderly People: A Meta-Analysis from The Medical and Health Sciences

Ashish Agarwal 1*, Sachin Pradhan 2

An IoT-based system enhancing elderly care, emphasizing QOL, independence, and support, aiding healthcare development for seniors' well-being.

Abstract | Full Text | PDF (670 KB) Open Access Article

  

Published online 08 December 2023

The Clinical, Histological, and Immunohistochemical Features of Bone Metastases - A Review

Ragini Patel 1*, Yogendra Sahu 2

A deep learning model to trace bone metastasis origins, addressing challenges in diagnosis and emphasizing therapeutic implications and monitoring.

Abstract | Full Text | PDF (698 KB) Open Access Article

  

Published online 12 December 2023

Hydrophobin-Coated Noisomes as Drug Carriers in Lung Cancer Cells - A Review

Srishti Namdeo 1, Chandrapratap Dhimar 2

Targeted nanoparticle delivery to Lung Cancer Cells, using hydrophobin-coated niosomes, addressing multidrug resistance, and enhancing treatment efficacy.

Abstract | Full Text | PDF (880 KB) Open Access Article

  

Published online 14 December 2023

Predictive Modeling of The Chronic Pain-Induced Depression in Old Adults Based on Music Intervention

Birendra Kumar Sahu 1, Chiranjeev Singh 2

This research addresses the prevalent issue of chronic pain in older adults, proposing a novel Predicting Chronic Pain-based Music Intervention model for personalized, effective treatment, showcasing promising results for mental well-being improvement.

Abstract | Full Text | PDF (1 MB) Open Access Article

  

Published online 14 December 2023

Analysis of Semi-Rural and Urban Hypertension Prevalence Using WHO Measures

Sumit Kumar Agrawal 1, Tripti Dewangan 2

Guiding a tailored intervention and strategy to advance global hypertension management

Abstract | Full Text | PDF (1 MB) Open Access Article

  

Published online 17 December 2023

Menopause-Related Insomnia, Cognitive, Behavioral, and Mindfulness-Based Treatments

Venu Anand Das 1, Jitendra Sinha 2

The study explores challenges in treating menopausal symptoms, introducing the Menopause-based Treatment Study Framework (MTSF) for more effective and enduring resolution.

Abstract | Full Text | PDF (1 MB) Open Access Article

  

Published online 17 December 2023

Epidermal Growth Factor Receptor and Double-Imprinted Nanoparticles for Targeted Cancer Drug Delivery - A Review

Lakhan Lal Kashyap 1, Harish Jaiswal 2

A targeted drug delivery approach, using double-imprinted nanoparticles and EGFR-SVM, to enhance anticancer drug effectiveness selectively in tumor cells.

Abstract | Full Text | PDF (446 KB) Open Access Article

  

Published online 19 December 2023

Identifying Thyroid Dysfunction Using Standard Laboratory Testings – A Systematic Review

Vinay Jaiswal 1, Prachi Gurudiwan 2

A ML-TDI model for thyroid dysfunction identification, addressing underdiagnosis challenges and emphasizing the importance of comprehensive assessment in care.

Abstract | Full Text | PDF (616 KB) Open Access Article

  

Published online 21 December 2023

Screening for Oral Cancer Using Brush Biopsies and DNA Image Cytometry - A Review

Pranjali Verma 1,  Shikha Kumari Rajak 2

A non-invasive DNAIC-DCNN for accurate oral cancer diagnosis, offering targeted medications for effective treatment.

Abstract | Full Text | PDF (401 KB) Open Access Article

  

Published online 21 December 2023

The Effect of Naturally Occurring Dietary Chemicals and Food-Borne Mycotoxins on DNA Methylation and Cancer - A Review

Moniza Nurez Khan 1, Naresh Chandravanshi 2

The critical impact of Food-Borne Mycotoxins (FBM) and Artificial Light At Night (ALAN) on DNA methylation, influencing cancer risk and disease outcomes.

Abstract | Full Text | PDF (325 KB) Open Access Article

  

Published online 22 December 2023

Analyzing the Influence of Initial Diagnosis on Interpersonal Problem Trajectories in Residential Treatment for Eating Disorders - A Review

Hemlata Dewangan 1, Neetish  Kumar 2

A systematic review of post-residential treatment outcome for eating disorders

Abstract | Full Text | PDF (662 KB) Open Access Article

  

Published online 25 December 2023

Physical Activity Correlates With The Aging Process in Seniors Broadly - A Review

Bhuneshwari Dewangan 1, Naina Bhoyar 2

A review of a correlation between physical activity, life satisfaction, and aging in the senior age group with Internet of Things (IoT) based Physical Activities (IoT-PA) model

Abstract | Full Text | PDF (406 KB) Open Access Article

  

Published online 29 December 2023

Brain-Computer Interfaces Can Significantly Improve The Quality of Life for Aged People - A Review

Sanjay Kumar Mire 1, Deepak Kumar Sahu 2

A non-invasive Brain-Computer Interfaces (BCIs) and IoT-based Smart Home Technology can enhance memory, focus, and aged people's quality of life.

Abstract | Full Text | PDF (625 KB) Open Access Article

  

Published online 08 January 2024

Gut-Brain Connection; IBS linked to Anxiety, Quality of Life, and Academic Performance in Undergraduate Students

Mohamed Sadeq Al-Ibrahim *1, Ahmad Hamdy Ibrahim 2, Sawsan S. Al- Rawi *3, Bayram Dawod Ahmed 4, Nalan Linda Fraim 5

Chronic stress affects many physiological processes including immunity and angiogenesis. IBS impacts anxiety, quality of life, and academic performance of undergraduate students.  

Abstract | Full Text | PDF (305 KB) Open Access Article

  

Published online 08 January 2024

A Review of Dipeptidyl Peptidase-4 (DPP-4) and its potential synthetic derivatives in the management of Diabetes Mellitus

Mohd. Javed Naim 1

To establish potential DPP-4 inhibitors. 

Abstract | Full Text | PDF (808 KB) Open Access Article

  

Published online 11 January 2024

Polycystic Ovarian Syndrome: An Overview with Special Consideration to Its Oral and Pediatric Clinical Manifestations

Zeba Saleem 1, Abiha Ahmad Khan *1, Syeda Aamena Naaz 1 and Mohd. Javed Naim 2

Highlighting the oral and pediatric manifestation of PCOS. 

Abstract | Full Text | PDF (1 MB) Open Access Article

  

Published online 12 January 2024

An In-Depth Analysis of Microorganisms Linked to Various Forms of Hospital-Acquired Infections: A Systematic Review

Nadirah Yusof 1,  Rabiatul Basria S. M. N. Mydin 1,2*, Chandrarohini Saravanan 2,3,4, Nor Hazliana Harun 2,5, Siti Salmah Noordin 5

The study aims to provide a detailed understanding of the microorganisms involved in different types of HAIs, such as surgical site infections, urinary tract infections, bloodstream infections, and respiratory tract infections.

Abstract | Full Text | PDF (247 KB) Open Access Article | Supplementary Material

  

Published online 12 January 2024

Platelet Implication in Atherosclerosis Pathogenesis

Anastasia V. Poznyak 1*, Varvara A. Orekhova 1, Vasily N. Sukhorukov 1, Alexandra A. Melnichenko 2, Elizaveta M. Pleshko 2, Alexander N. Orekhov 1

Platelets' vital role in health, thrombosis, atherosclerosis; therapy's ongoing clarification.

Abstract | Full Text | PDF (541 KB) Open Access Article

  

Published online 15 January 2024

Maternal Hypercholesterolemia is a Significant Risk Factor for Atherogenesis – A Systematic Review

Anastasia V. Poznyak 1*, Victoria A. Khotina 2, Vasily N. Sukhorukov 2, Nikolay Sadykhov 2, Anton Y Postnov 2, and Alexander N. Orekhov 2*

Maternal hypercholesterolemia during pregnancy influences fetal development, leading to lasting atherosclerotic changes, emphasizing preventive strategies to reduce future cardiovascular disease burdens.

Abstract | Full Text | PDF (935 KB) Open Access Article

  

Published online 16 January 2024

An Educational Intervention to Improve Adverse Drug Reactions Reporting Among Healthcare Practitioners in Selected Pediatric Hospitals in Iraq

Bootan A. Salih 1,*, Omer Q. Allela 2, Raad A Kaskoos 3, Javed Ahamad 4

The main goal of the study is to design an intervention program to increase knowledge attitude and practice of healthcare practitioners towards pharmacovigilance.

Abstract | Full Text | PDF (738 KB) Open Access Article

  

Published online 17 January 2024

Innovative Piperidine-Catalyzation in Protecting Carbonyl Compounds with Implications for Angiogenesis and Inflammation

Mukhlif Mohsin Slaihim 1*, Luay Ali Dhahi 1, Abeer Hussein Ali 1

Introduced piperidine-catalyzed protection in aldehydes, guiding anti-cancer compound optimization.

Abstract | Full Text | PDF (804 KB) Open Access Article | Supplementary Material

  

Published online 18 January 2024

Effect of Toll-Like Receptor 9 (TLR9) in Breast Cancer Risk, Along with Hormonal Effects in Patients Receiving Radiotherapy

Asra'a Adnan Abdul-Jalil 1, Marrib N. Rasheed 2, Rana H. Hamoode 3

TLR9 rs187084 polymorphisms crucial in Iraqi women's breast cancer susceptibility.

Abstract | Full Text | PDF (298 KB) Open Access Article

  

Published online 19 January 2024

Optimizing Fast-Dissolving Tablets of Ketotifen: Impact of Sodium Bicarbonate and Citric Acid in Formulation and Evaluation

Rozhan Arif 1, Sharad Visht 1*, Ali Omar 1, Sana Sirwan Salih 1

Formulating ketotifen fast-dissolving tablets (FDT) tackled poor bioavailability challenges, emphasizing sodium bicarbonate's pivotal role for rapid tablet disintegration, highlighting FDT viability for asthmatic treatment.

Abstract | Full Text | PDF (571 KB) Open Access Article

  

Published online 20 January 2024

Significance of Serum Biomarkers in Early Diagnosis of Hepatocellular Carcinoma in Patients with Fisher Groups

Tufael 1, Auditi Kar 2, Vijay Jagdish Upadhye 3*, Amith Dutta 4, Md Royhanur Islam 5, Abdus Sattar 6, Md. Eunus Ali 7, Julakha Akter 8, Kaniz Fatima Bari 9, Md. Tahsin Salam 10, Palash Chandra Banik 11, Md Shamsuddin Sultan Khan 12, Atiqur Rahman Sunny 13*

The research addresses a crucial gap by linking the unique lifestyle and stressors in fisher groups to hepatocellular carcinoma.

Abstract | Full Text | PDF (409 KB) Open Access Article

  

Published online 20 January 2024

Advancing Therapeutic Efficacy of Star Anise Oil with (Illicium verum) Nano-Emulsion Formulation

Sharad Visht 1, Sana Sirwan Salih 1, Belan Azad Ibrahim 1, Daniah Issa Ismael 1, Serwa Falah Abdalwaheed 1, Omji Porwal 1

Star anise oil-based nano-emulsions' extraction, purification, and formulation processes to improve therapeutic efficacy of drug substances

Abstract | Full Text | PDF (1 MB) Open Access Article

  

Published online 20 January 2024

A Review of Healing Potential of Indian Flora: An Ethnopharmacological Evidence of Wound Healing Activity

Rasmita Jena 1,2, Durga Madhab Kar 1*, Sovan Pattanaik 1, Bhisma Narayan Ratha 3

This review emphasizes the rich potential in traditional practices, offering valuable insights and solutions to current healing challenges.

Abstract | Full Text | PDF (934 KB) Open Access Article

  

Published online 21 January 2024

Renal and Hepatic Toxicity of Alpha-Cypermethrine Pesticide Used on Agricultural  Farmers Living Closed to Tigris river, Iraq

Sarhan Rashid Sarhan 1*,   Mohammed H.M. Merah 2

ALP, ALT and AST enzymes increased significantly when directly exposed to this pesticide as a result of its effect on kidney and liver functions.

Abstract | Full Text | PDF (436 KB) Open Access Article

  

Published online 21 January 2024

Therapeutic Effects of Esomeprazole, Curcumin, Chitosan, and Curcumin-Chitosan Mixture on Ethanol-Induced Gastric Ulcer in Female Rats

Jenan Mahdi Jawad Al-kawaz 1*, Fakhir Magtoof Al-Zubaidy 2**, Hussein Jassim Obaid Al -Harbi 1***

Evaluate the healing effects of esomeprazole, curcumin, chitosan, and a curcumin-chitosan mixture on gastric injuries induced by ethanol in rats.

Abstract | Full Text | PDF (737 KB) Open Access Article

  

Published online 21 January 2024

Synthesis And In-Silico Anti-Cancer Potential of N-Aryl-Keto-Nitrone As A Spin Adducts

Rita S. Adam 1*

Advancing spin trapping chemistry through the introduction of effective linear keto-nitrones, expanding applications and refining practical use.

Abstract | Full Text | PDF (463 KB) Open Access Article

  

Published online 22 January 2024

Effect of Metformin and Vitamin D Supplementation on Metabolic and Hormonal Profiles in Polycystic Ovary Syndrome Women: A Follow-Up Study

Zainab Nur-Eldeen Aziz 1*, Basil O. Saleh 1

Positive Impacts of Metformin and Vitamin D Supplementation on Polycystic ovary syndrome (PCOS) Women

Abstract | Full Text | PDF (232 KB) Open Access Article

  

Published online 22 January 2024

Anti-Cancer Study of Carvacrol in Hypoxic-Induced Colorectal Cancer Cell

Aumaima Tariq Abed 1,2* ,  Ahmed MH AlMudhafar 1 , and Najah R Hadi 1

Effect of carvacrol on proliferation and migration of hypoxic SW480 cancer cells

Abstract | Full Text | PDF (586 KB) Open Access Article

  

Published online 22 January 2024

Effect of Steroid Treatment on Tissue Damage Markers in Diabetic Patients

Mohammed Shakir Ali 1*, Ali Al-Shammari 1, Qutaiba A. Ismael 1, Obaida Amer Imran 1, Mohammed H. Al-Bayati 1

This research showed how diabetes and steroids worsen effects, providing a better understanding of the pathophysiology processes.

Abstract | Full Text | PDF (381 KB) Open Access Article

  

Published online 22 January 2024

Synthesis, Characterization and In Vitro Anti-cancer  Properties of Cationic Gemini Surfactants with Alkyl Chains in Human Breast Cancer

Anwar Shalan F. 1*, Samah Hussein Kadhim 1

Anti-cancer activity of Gemini surfactants in human breast cancer cells

Abstract | Full Text | PDF (1 MB) Open Access Article

  

Published online 22 January 2024

Impact of Various Contraceptive Methods on Immunological Profiles in Women: A Serological Analysis in Diyala Governorate

Shaymaa Mohammed Alwan 1, Maha Falih Nazzal 2, Inaam Faisal Mohammed 3

Abstract | Full Text | PDF (272 KB) Open Access Article

  

Published online 22 January 2024

Two Forms of C-Reactive Protein and Their Implication for Atherogenesis: Focus on Monomeric Form

Anastasia V. Poznyak 1*, Victoria A. Khotina 2, Anton Y Postnov 2, Vasily N. Sukhorukov 2, Nikolay Sadykhov 2, Alexander N. Orekhov 2*

A review on inflammatory protein in atherosclerosis progression.

Abstract | Full Text | PDF (1 MB) Open Access Article

  

Published online 22 January 2024

Machine Learning-Based Enhanced Drug Delivery System and Its Applications – A Systematic Review

Abhijeet  Madhukar Haval 1*, Kumar Shwetabh 1, Sushree Sasmita Dash 1

Machine Learning (ML) transforms drug development, predicting drug properties, targets, interactions, and facilitating efficient exploration for researchers and pharmaceutical companies.

Abstract | Full Text | PDF (528 KB) Open Access Article

  

Published online 23 January 2024

A Systematic Review of Advanced Approaches in Wound Healing: Simvastatin Polymeric Nanoparticles and Postbiotics Innovation

Chandrapratap Dhimar 1*, Krishna Sahu 1, Moniza Nurez Khan 1

Utilizing innovative postbiotics and Simvastatin Polymeric Nanoparticles, wound research accelerates healing, promising improved treatment with minimal inflammation.

Abstract | Full Text | PDF (682 KB) Open Access Article

  

Published online 23 January 2024

A Review of Modeling Checkpoint Blockade Therapy and Therapeutic Strategies in Integrative Pharmacological Approach for Metastatic Breast Cancer

Prachi Gurudiwan 1*, Ragini Patel 1, Urvashi Jain 1

Quantitative Systems Pharmacology models immune processes in breast cancer, aiding personalized treatment by identifying biomarkers, resistance mechanisms, and therapeutic options

Abstract | Full Text | PDF (1 MB) Open Access Article

  

Published online 23 January 2024

In vitro Antibacterial Activity of Seribu kuman Leaf (Rhinacanthus nasutus (l.) Kurz) Extracts Against Staphylococcus aureus and Pseudomonas aeruginosa

Betty Fitriyasti 1*, Siska Ferilda 2, Widia Sari 3, Muhammad Rizki Saputra 4, Heng Yen Khong 5*

Rhinacanthus nasutus extract inhibits the growth of Staphylococcus aureus and could serve as an alternative in treating infections caused by S. aureus.

 

Abstract | Full Text | PDF (396 KB) Open Access Article

  

Published online 24 January 2024

The Characterization of Acute Myeloblastic Leukemia-M2 Cell Lines with Suppressed Stromal Interaction Molecule 1 (STIM1) and its Impact on Calcium/Reactive Oxygen Species Profiles

Eman Salem Algariri 1,2, Rabiatul Basria S. M. N. Mydin 1*, Emmanuel Jairaj Moses 1, Nur Arzuar Abdul Rahim 3, Narazah Mohd Yusoff 3

STIM1's potential role in promoting AML-M2 cell survival by regulating calcium/ROS interactions, as well as KRAS/MAPK and Akt-related pathways

Abstract | Full Text

  

Published online 24 January 2024

A Comprehensive Review on Cardiovascular Disease Detection, Risk Assessment, And Treatment Using A Network Pharmacology Model

Vijay Kumar Jaiswal 1*, Monika Barsagade 1, Jitendra Sinha 1

Contribution to advancing diagnostic methods, proposing innovative treatment approaches, and demonstrating the effectiveness of pharmacist-led preventive strategies for improving population health, reducing the economic burden of cardiovascular diseases, and showing more personalized and mechanism-based approaches in healthcare.

Abstract | Full Text | PDF (834 KB) Open Access Article

  

Published online 24 January 2024

Advancements in Ocular Vascularization Analysis Using Deep Learning Techniques – A Systematic Review

F Rahman 1*, Akanksha Mishra 1, Sushree Sasmita Dash 1

This review shows an advanced machine learning method for efficient segmentation and classification of blood vessels in medical images, revolutionizing diagnostic precision.

Abstract | Full Text | PDF (975 KB) Open Access Article

  

Published online 25 January 2024

Advances of AI-driven Drug Design and Discovery in Pharmaceuticals - Review

Dev Ras Pandey 1*, Sushree Sasmita Dash 1, Akanksha Mishra 1

The application of AI in pharmaceuticals holds the promise of personalized therapies, streamlined production, and improved market strategies, making it an indispensable tool for the future of drug development.

Abstract | Full Text | PDF (1 MB) Open Access Article

  

Published online 25 January 2024

Smart Wound Monitoring and Healing Assessment System With Deep Learning Methods - A Systematic Review

Abhijeet  Madhukar Haval 1*, Akanksha Mishra 1, Sushree Sasmita Dash 1

Wound features impact healing; indicators like temperature, oxygen levels, and moisture influence the process. This review shows and effective at-home wound monitoring with biosensors.

Abstract | Full Text | PDF (962 KB) Open Access Article

  

Published online 26 January 2024

Advances in Image Processing Methods for Breast Cancer Diagnosis and Classification Using A Hybrid Machine Learning – A Systematic Review

Priya Vij 1, Sushree Sasmita Dash 1, Akanksha Mishra 1

Advanced integration of deep learning (AlexNet) and SVM-RBF for breast cancer diagnosis surpasses existing models, ensuring precise and reliable early detection.

Abstract | Full Text | PDF (899 KB) Open Access Article

  

Published online 26 January 2024

A Pharmacy System Integrated with A Machine Learning Algorithm for Cardiovascular Disease Prediction

Kumar Shwetabh 1*, F Rahman 1, Sushree Sasmita Dash 1

The review explores an inclusive ML structure, vital for efficient CVD forecasting. The proposed model showcases superior accuracy, emphasizing the need for comprehensive predictive algorithms in cardiovascular health research.

Abstract | Full Text | PDF (1 MB) Open Access Article

  

Published online 05 February 2024

Vitamin D Deficiency As A Contributor To Atherosclerosis Development – A Review

Anastasia V. Poznyak 1*, Victoria A. Khotina 2, Alexandra A. Melnichenko 2, Victor Y Glanz 2, Vasily N. Sukhorukov 2, and Alexander N. Orekhov 2*

Vitamin D deficiency and cardiovascular diseases, explores role in inflammation, oxidative stress, and vascular calcification

Abstract | Full Text | PDF (900 KB) Open Access Article

  

Published online 08 February 2024

Repurposing Drugs for Overcoming Therapy Resistance in Colon Cancer – A Review

Mahdi Darvishi 1, Amir Mohammad Chekeni 2, Mohammad Fazelhosseini 1, Zeenat Iqbal 3*, Mohd Aamir Mirza 3*, Perwez Alam 4, Ali Akhtar 4, Mohd. Aslam 5, Esra Tariq Anwer Bayrakdar 5

Oncology research seeks new therapies for aggressive CRC, utilizing repurposed drugs for accelerated and safer treatment approaches.

Abstract | Full Text | PDF (445 KB) Open Access Article

  

Published online 09 February 2024

A Review of 3d Printing Model of New Blood Vessel Formation For Pharmaceutical Applications

Nidhi Mishra 1*, Priya Vij 1, Akanksha Mishra 1

Innovative synthetic blood vessels offer promising solutions for cardiovascular diseases, providing safer, more accessible treatments for aging populations

Abstract | Full Text | PDF (535 KB) Open Access Article

  

Published online 09 February 2024

Efficient Removal of Acetamiprid Pesticide Using Date Core-Derived Activated Carbon and Korai Clay As A Good Sorbent

Huda Azhar Fadel 1*,  Lekaa Hussein Khdaim 1

Iraqi date core-derived activated carbon effectively removes acetamiprid pesticide, crucial for combating water pollution, supported by comprehensive adsorption studies.

Abstract | Full Text

  

Published online 12 February 2024

A Double-blind, Randomized Clinical Trial Study of Plantago major l. Syrup on Menorrhagia

Sajedeh Ghasempour 1, Mohsen Naseri 2, Fatemeh Alijaniha 2, Yasin Karimi 3, Anoushirvan Kazemnejad 4, Shahrzad Hadavand 5 , Seyedeh Fatemeh Jafari 2

The study highlights Plantago major's potential to reduce menorrhagia severity and duration, offering a promising complementary treatment with minimal side effects.

Abstract | Full Text | PDF (329 KB) Open Access Article

  

Published online 13 February 2024

Understanding and Combatting COVID-19: Insights from Clinical Characteristics and Management Strategies

Bala Krishnan A 1, Vigneshwaran V 1, Tharani Kumar L 1, M. Shagar Banu 1

Timely analysis is crucial for understanding and combating global health crises like COVID-19 effectively

Abstract | Full Text

  

Published online 13 February 2024

Concerning Fungal Coinfections in COVID-19: Risks, Types, and Prevention – A Review

Bala Krishnan A  1, Vinoth Kumar K K 1, Tharani Kumar L 1, M. Shajini G Inbakani 1

The review highlights the alarming rise of fungal infections like Mucormycosis among COVID-19 patients, necessitating prompt diagnosis and care to prevent fatalities.

Abstract | Full Text

  

Published online 13 February 2024

Unprecedented Rise of Mucormycosis in COVID-19 Patients: Urgent Need for Protocol Adaptation and Awareness in India – A Review

Nithya A 1, Vinoth S V 1, Ashok Kumar M 1, Sindhu T 1

Mucormycosis in COVID-19 patients in India necessitates urgent updates in treatment protocols and public awareness

Abstract | Full Text

  

Published online 14 February 2024

Navigating COVID-19 Treatment: CT Scans, Steroids, and Medical Practice Challenges in India

Jayanthi E 1, C. Elayaraja 2, Priyadharshini S 2, Ashok kumar M 2

The review highlights India's struggle with COVID-19, emphasizing the need for tailored treatments amid rising cases, cautioning against unnecessary tests and misuse of medications.

Abstract | Full Text

  

Published online 14 February 2024

In vitro Cytotoxicity and Apoptotic Activity of Aquous, Chloroform and Methanol Extracts of Kiwi Fruit Actinidia deliciosa in MCF-7 cells

Kartheeswari 1, Archana C 1, Anupreyaa K 1, Saranya M 2

Assessment of A. deliciosa extracts' anticancer potential on MCF-7 cells offers insights for natural cancer medication development

Abstract | Full Text

  

Published online 15 February 2024

Impact of Dapagliflozin on Atherosclerosis through Inflammation and Oxidative Pathways

Zainab Abdlkadhim Aboshnin 1*, Safa Azhar Razzaq 1, Zahraa Ibraheim Jawad Shubber 2

Atherosclerotic patients need therapies targeting inflammation and oxidation. This study supports Dapagliflozin's use for clinical benefits in atherosclerosis.

Abstract | Full Text

  

Published online 15 February 2024

Association Between Low Bone Mineral Density in Hemophilia Patients and Musculoskeletal Function Impairments

Rasha Ibrahim Salman 1* , Khalid Mahdi Salih 1*, Nidal Karim Al-Rahal 2*

Hemophilia patients with low bone density (BMD) face higher risk with severe limitation of movement (LOM) and viral infections.

Abstract | Full Text | PDF (923 KB) Open Access Article

  

Published online 16 February 2024

The Analysis of Hypertension Knowledge in Adults in Telafer City: Implications for Health Education and Intervention

 Mohammed Qassim Baktash 1* , Ali Ismael Sulaiman 1

Understanding hypertension in Telafer City adults is vital for preventing problems, guiding interventions, and managing the disease effectively

Abstract | Full Text

  

Published online 17 February 2024

The Analysis of Hematological Parameters CBC, ABO, NLR, and APTT and Its Implications on Haemophilic Patients with Low Bone Mineral Density

Rasha Ibrahim Salman 1* , Khalid Mahdi Salih 1, Nidal Karim Al-Rahal 2

The study determined a high prevalence of low bone mineral density in hemophilic patients, associated with elevated NLR and prolonged APTT.

Abstract | Full Text

  

Published online 17 February 2024

Efficacy of Paromomycin-Conjugated Nano Chitosan in Treating Entamoeba histolytica Infection in Mice

Hajar Falih Hishan Aldali 1*, Shatha Khudiar Abbas 1, Ahmed Naji Abd 1

Entamoeba histolytica causes widespread amebiasis. Chitosan-paromomycin nanoconjugates effectively treated infected mice, reducing liver enzyme levels, showing promising therapeutic potential.

Abstract | Full Text

  

Published online 17 February 2024

Anti-Cancer Activity of Allium Ascalonicum Ethanol Extract Against Human Hepatocellular Carcinoma Cell Line (HepG-2)

Geetha N B 1*, Chintala Venkatesh 1, Suresh M 1, Manikandan S 2

Allium ascalonicum might be a safer, more effective alternative to toxic chemotherapy for combating cancer with targeted potency.

Abstract | Full Text

  

Published online 18 February 2024

In vitro Anti-cancer Activity of Methanol Extracts of Kiwi Fruit, Actinidia deliciosa in HCT-119 Cells

Geetha N B 1, Priya R 1, Weslin D 1, Ashmi Christus A T 2

The study of anti-cancer properties of Actinidia deliciosa methanol extract in Colorectal cancer as effective treatments.

Abstract | Full Text

  

Published online 18 February 2024

Green Fungus Challenges in Post-COVID Health Landscape

Jeha J 1, Sudha S 1, Geetha N B 1, Benitta Sherine S 2

This review provides Green Fungus challenge in post-COVID situation. Early detection, hygiene, and research are imperative.

Abstract | Full Text

  

Published online 18 February 2024

Diagnosis of Chronic Brucellosis with Interferon-Gamma Quantification

Sarah Yahya Abdullah 1, Yasir Mufeed Abdulateef 2*, Sawsan Qahtan Taha Al-Quhli 3

This study showed the improvement of brucellosis diagnosis using interferon-gamma for better detection in chronic cases

Abstract | Full Text

  

Published online 19 February 2024

Epidemiological Analysis of Hepatitis B and C Viruses in Fallujah for Health Intervention and Disease Control

Ahmed Saadi khlaf 1*, Asif Hasan Abdulrazaq 2, Nawar Bahaa Abdulsahib 3, Manaf Akram Ismaell 3, Mustafa Asif Hasan 3

Investigating Hepatitis B and C in Fallujah revealed higher prevalence among males, aiding targeted interventions and public health initiatives.

Abstract | Full Text

  

Published online 19 February 2024

A study of Enhancing Fencing Skills with The Impact of Special Exercises on Kinetic Response and Attack Accuracy among Young Foil Players

Reem Mohammed Abdel Wahhab 1*

This study showed an improved exercise enhancing kinetic response, vital for fencing to optimize athletes' and their healthy performance.

Abstract | Full Text

  

Published online 19 February 2024

Determination of Demographic Liver Health with Giardia lambila Infection Analysis in Diyala

Noora Dhyaaldain Abed 1*, Shahad Abdul Jabbar Mohammed 2*

This study analyzed the Giardia infection as early detection for liver health intervention.

Abstract | Full Text

  

Published online 20 February 2024

Salmonella Biofilms And Antibiotic Resistance Determination From Different Patient Types

Mariam Ayad Abd 1*, Sawsan Q. T. Al-Quhli 2, Mahir Ali Jassim 3

This study discussed important information about antibiotic resistance and how harmful Salmonella bacteria are in Iraqi patients, helping to plan better public health measures.

Abstract | Full Text

  

Published online 20 February 2024

Cumin Extract Alters The Histology of Kidney and Duodenum in Adult Rabbit

Hussein B. Mahmood 1*,  Naseer  A. Al-Arubaye 1, Walaa F. Obead 1

This study showed the histological alterations of the kidney and duodenum due to excessive use of cumin.

Abstract | Full Text

  

Published online 20 February 2024

Treatment of High-Fat Diet-Induced Obesity and Insulin Resistance Using Rose Flowers (Rosa damascena) in Rat

Kamran Javed Naquvi 1*, Javed Ahamad 1

Rosa damascena petals reduce obesity-related markers and insulin resistance. This is a natural agent for metabolic health improvement and weight management.

Abstract | Full Text

  

These articles have been peer reviewed and accepted for publication. They are still in production and have not been edited, so may differ from the final published form.

Published online 07 January 2019

Modes of Anti-angiogenesis in Chemical Perspectives

Shan Arif a, b, Muhammad Imran a, b, Muhammad Adnan Iqbal a, b

In the current study, role of synthesized chemical pharmacores like Humulus lupulus, Hypericum perforatum, Panax ginseng, Coptis chinensis and Rheum palmatum (Varinska et al., 2010) as anti-angiogenesis has been compiled. 

Abstract


Published online 04 February 2019

Ethosomal formulation composed of standardized Orthosiphon stamineus extract and sophorolipid inhibits angiogenesis of melanoma in vivo

Mansoureh Nazari Vishkaei a, Mohamed Khadeer Ahamed Basheer c, Amin Malik Shah Abdul Majid a,b

SLOS vesicles can be considered for effective dermal therapeutic agent for the treatment of skin cancer.

Abstract


Published online 11 May 2019

Anti-GBM potential of Rosmarinic acid and its synthetic derivatives via targeting IL17A mediated angiogenesis pathway

Md Shamsuddin Sultan Khan A,C,E, Mohammad Adnan Iqbal B, Muhammad Asif A, Tabinda Azam B, Majed Al-Mansoub A, Rosenani S. M. A. Haque B, Mohammed Khadeer Ahamed Basheer C, Aman Shah Abdul Majid D, Amin Malik Shah Abdul Majid A,C,E*

Metal salts and base rosmarinates demonstrated potent anti-GBM efficacy as IL17A inhibitor with minimal toxicity.   

Abstract


Published online 15 May 2019

Ascorbate blocks acetylcholine- and bradykinin-induced vasodilatation in retinal vascular bed of the bovine isolated perfused eye

Li-xin XU A, Xiao-bo XIA B, Aman Shah Abdul Majid C, Dan Ji B

This study provides insight to EDHF-mediated vasomotor response, as well as various eye disorders caused by dysfunctional retinal arteries, like central retinal artery occlusion.

Abstract


Published online 24 June 2019

Evaluation of Safety and Efficacy of Labeesity® for Weight Management and Fatigue in an Obese Female Patient with Hypothyroidism: A Case Report

Aman Shah Abdul MajidA*, Elham FarsiB, Natesan VijayalakshmiC, Syarifah Aisya Syed AmranD, Mahibub Mahadmadsa KanakalE, Zarina Thasneem ZainudeenF*

Labisia pumila extracts based products will require robust studies to be conducted utilizing larger patient numbers and over extended periods of time to rule out any potential toxic effects.

Abstract


Published online 03 November 2019

Extract of Urgenia grandiflora inhibited breast cancer cell (MCF-7) proliferation and tumorgenesity

Ibrahim B. E. El Bashir A,B, Loiy Elsir Ahmed HassanC, Amin M. S. Abdul Majid D, Sakina Yagi A*

U. grandiflora could be a new source of chemotherapeutic for breast cancer.

Abstract


Published online 30 December 2019

Acute and Sub- chronic Toxicity Study of Encapsulation of Combine Plants Extract of Ficus deltoidea and Gynocthodes sublanceolata in Balb/c Mice Model

Rafida Kh. Ahmed A, M. Syarhabilahmad A, Midhat Nabil A, Fouad Saleih R. Al –Suede B,*

Oral treatment with encapsulated plant extract Ficus deltoidea and Gynocthodes sublanceolata did not appear adverse side effect and it is safe to use for therapeutic purposes.

Abstract


Published online 08 July 2020

Phytochemicals in Cancer with Special Emphasis on Ovarian Cancer

Meher U Nessa1,2, Md S Anwar1, Fazlul Huq3*

Reviews current literature on use of phytochemicals in prevention and therapy of ovarian cancer including mechanism of action.

Abstract


Published online 12 September 2020

Dose Dependent Synergism from Combination of Platinum Drugs with Curcumin against Colorectal Cancer Cell Lines

Hana Bali1, Jun Qing Yu1, Philip Beale2, and Fazlul Huq3

Ox in combination Cur demonstrated very high synergism against HT-29 and Caco-2 cell lines.

Abstract


Published online 13 March 2021

Immunomodulatory and Antiangiogenic Mechanisms of Polymolecular Botanical Drug Extract C5OSEW5050ESA OS Derived from Orthosiphon stamineus

Fouad Saleih R. Al-Suede1*, Mohamed B. Khadeer Ahamed1, Aman S. Abdul MajidSultan Ayesh Mohammed Saghir3, Chern E. Oon4, Amin Malik Shah Abdul Majid1,5*

C5OSEW5050ESA OS strongly curbs variety of angiogenesis modulators in vitro, ex vivo and in vivo.

Abstract


Published online 30 October 2021

Cannabis Sativa: A Remedy for Convulsion by Inhibition of GABAA Receptor and Significantly Delayed Onset of Seizure Latency and Death - An Experimental Validation and Molecular Docking

Ben Enoluomen Ehigiator1, SamuelKelechi Mobisson2, Iheanyichukwu Wopara3*, Chinonye Cynthia Chibuife1, Uwaezuoke Chukwuekele Awarajih3, Harrison Ogheneochuko Eruotor3

Abstract


Published online 10 November 2021

Immunomodulatory Effect of Tinospora cordifolia with Special Reference to Suppression of Cytokine Storm Induced in SARS-CoV-2

Aishath Thahuseen Waheed1, Thurga Ayavoo2,3, Karthikeyan Murugesan2,3,  Fouad Saleih R. AL-Suede4,5, Ashok Gnanasekaran2,3*

Development of anti-inflammatory herbal drug.

Abstract


Published online 11 November 2021

Phytochemicals with Direct and/or Indirect Anti-angiogenic Properties Against Various Cancer Types Focusing on Their Mechanism of Action

Ibrahim Al-deeb1,2,3, Julia Joseph1, Amin Malik Shah Abdul Majid2, Nozlena Abdul Samad1

Abstract


Published online 02 February 2022

Evaluation on Antibacterial Activity and Hepatoprotectivity of Rauwolfia serpentina

Gnanasekaran Ashok1,6*, Yukshna A/P Ramunaidu2, Fouad saleih R.AL-Suede3,4 Murugesan Karthikeyan1, Pugazhandhi Bakthavatchalam5, Sajeewa P.  Rathnayake6

The results of this study provide scientific evaluation of antibacterial activity and hepatoprotective effect of Rauwolfia serpentina which will be useful to researchers investigating the compounds with this potential and encouraging the development of new findings in this field.

Abstract


Published online 04 March 2022

A Systematic Review on Temporal Lobe Epilepsy Patients with Corona Virus Infection

Pugazhandhi Bakthavatchalam1, Fouad Saleih R.AL-Suede2,3, Sudarshan S.1*

Abstract


Published online 04 April 2022

Comparison of anti-inflammatory and analgesic effects of artocarpin-rich Artocarpus heterophyllus extract and artocarpin

Rizwan Rashid Bazmi1, Muhammad Asif2**, Hafiza Sidra Yaseen3, Pharkphoom Panichayupakaranant1,4*

The present study has an impact on overcoming the inflammation problem, which can lead to various types of chronic inflammatory diseases, using the artocarpin  & artocarpin-rich Artocarpus heterophyllus extract. The primary significance of this research is the achievement of preparation of a natural anti-inflammatory and analgesic agent using a green chemistry, which contributes to combat inflammation and analgesia. Furthermore, this method is practically used for industrial commercialization.    

Abstract


Published online 20 April 2022

Anti-tumor Activity of NuvastaticTM (C5OSEW5050ESA) of Orthosiphon stamineus and Rosmarinic Acid in An Athymic Nude Mice Model of Breast Cancer

Ashwaq Hamid Salem Yehyaa,*, Majed Ahmed Al-Mansoubb, Fouad Saleih Resq Al-Suedea, Siti Balkees Binti STN Hameed Sultana, Muhammad Asyraf Abduramana, Noor Amanina Azmic, Mufda jameel abedalhadi alrawashdehd, Seyedeh Fatemeh Jafarie, Amin Malik Shah Abdul Majida,f

Abstract


Published online 02 July 2022

Therapeutic Targeting on Death Pathways in Glioblastoma

Pavithra Suppiah1, Julia Joseph1, Rolla Al-Shalabi1, Nik Nur Syazni Nik Mohamed kamal1, Nozlena Abdul Samad1*

Abstract


Published online 24 August 2022

Hepatoprotective effect of Hydro-alcohol extract of Mimusops elengi root against antitubercular drug-induced hepatotoxicity in rats

Prakash Dabadi1, Fouad Saleih Resq AL-Suede2,3*, Chandrashekhar VM4*, Mallappa Shalavadi 4 , Ashok Gnanasekaran5

Development of therapeutics for the treatment of hepatotoxicity and oxidative stress  induced by ATDs

Abstract


Published online 17 September 2022

Targeting Microtubules by Phytoestrogens for the Treatment of Cancer: An Overview

Fan Xu1, Nozlena Abdul Samad1, Nurhuda Mohamad Ansor1*

In this review, we summarize reported effects of some phytoestrogens that bind directly to tubulin at various binding site and disrupt the microtubule dynamics, either by promoting microtubule polymerization or enhancing microtubule depolymerization.

Abstract


Published online 25 September 2022

Environmental and physiological angiogenesis in causing CVD with oxidative pattern

Md. Fakruddin1*, Md. Asaduzzaman Shishir2, Kumkum Rahman Mouree2, Shamsuddin Sultan Khan3

Oxidative stress plays critical role in angiogenesis and cardiovascular disease progression. Drugs targeting oxidative stress might provide a new treatment paradigm for related disorders.

Abstract


Published online 04 October 2022

Ferritin and High Sensitivity C-Reactive Protein (hs-CRP) may predict the COVID-19 patient’s fate

Zahra A. Kheudhier1*, Alaa K. Mossa2

Circulating biomarkers are an essential predictor for the prognosis of COVID-19-infected patients as they represent the severity of inflammation and immune status.

Abstract


Published online 04 November 2022

Prognostic Factors and Predictors of Mortality in Patients with Critical Limb Ischemia: A Current Clinical Perspective

Moniruddin Chowdhury1,2, Syeda Humayra2, Sohel Mahmud3, Yukihito Higashi4, YD Singh1

PAD and its impact in physical impairment or mortality.

Abstract


Published online 15 November 2022

Efficacy of Herbal Medicine as Adjunctive Therapy for Skin Cancer

Norbayu Mansor1, Julia Joseph1, Rola Al Shalabi1, Nozlena Binti Abdul Samad*1

Phytochemicals can be used for skin cancer prevention and treatment.

Abstract


Published online 22 November 2022

Immunoglobulin G Seroprevalence of Lassa Fever Virus Among Individuals Residing Along the Banks of River Niger in Anambra State, Nigeria.

Umezurike Kingsley Chimuanya1, Chukwuma Oluchukwu Mariagoretti1,2, Ochiabuto Mary Barbara1, Manafa Patrick Onochie1, Ntum Ifeanyichukwu Michael1, Chukwuma George Okechukwu1,2

LF-specific IgG seroprevalence among inhabitants of river banks in Anambra State, Nigeria

Abstract



Published online 24 December 2022

Cancer Immunotherapy in 2022 - End of the Beginning

Assoc. Prof. Dr. Toh Han Chong

Abstract




Published online 24 December 2022

Precision Medicine in Lymphoid Malignancies

Prof. Dr. Richard Rosenquist Brandell

Abstract





Published online 24 December 2022

Updates on Treatment of Gastroesophageal Cancers

Prof. Dr. Ho Gwo Fuang

Abstract


Published online 24 December 2022

Insights into Advanced Non-Small Cell Lung Cancer Patients with MET Alterations

Emeritus Prof. Dr. Liam Chong Kin

Abstract






Published online 24 December 2022

Targeted Delivery of Cisplatin Using RGD-Modified ZIF-90 as Delivery Vehicle

Emilia Abdulmalek1,2,*, Adamu Abubakar1,3, Kyle. E. Cordova4, Mohd Basyaruddin Abdul Rahman1,2,5

Abstract



Published online 24 December 2022

Molecular Modelling Analysis of Squamocin as Potential BCL-XL Anti-apoptotic Protein Inhibitor

Kaynat Khimani1, Mohd Faiz Abdul Ghani1,2, Rozana Othman3, Noraziah Nordin1,*

Abstract


Published online 24 December 2022

Differential Cell Cycle Arrest in Dihydroorotate Dehydrogenase (DHODH) Inhibition of Different Subtypes of Breast Cancer Cell Lines 

Muhammad Aiman Akmal Shahhiran1,2, Mohamad Fairus Abdul Kadir3, Nurshamimi Nor Rashid1,2, Shatrah Othman1,2,* 

Abstract


Published online 14 May 2023

Investigation Of Anti-Tumour Activity Of Orthosiphon Stamineus On Human Oral Squamous Cell Carcinoma

Shah kamal Bin Jamal Dina, Fouad Saleih Resq Al-Suedeb,c*,Farahnaz Aminid, Aman Shah Abdul Majide, JackTan Chun Keatd, Amin Malik Shah Abdul Majidf .

The potential of Nuvastatic in the treatment of oral squamous cell carcinoma.

Abstract


Published online 07 July 2023

Use of Neutralizing Monoclonal Antibodies and Its Outcome Measures in COVID-19 Patients

Moniruddin Chowdhury1,2, Syeda Humayra2, Taha Sulayman3, Keichiro Mihara4, P.K. Rajesh1

The use of monoclonal antibodies in Covid-19.

Abstract


Published online 23 July 2023

Diagnostic and differential efficacy of cyclin D1 and CA15-3 in breast cancer and benign breast tumors

Anmar R. Raheem1,2, Omar F. Abdul-Rasheed1*, Omar S. Khattab3, Ahmed Z. Abdulhameed4, Hussein A. Abid1,5*

Abstract


Published online 29 July 2023

Design, Synthesis, And Characterization Of New Schiff Bases For 3-Amino-1,2,4-Triazole-5-Thiolate Salt, Bearing Morpholine Ring And Biological Evaluation As Antibacterial Agents

Abeer Hussein Alia, and Mukhlif Mohsin Slaihimb*.

Antibacterial efficacy of new chemical compounds named benzaldehyde derivatives.

Abstract


Published online 12 August 2023

A review of the effects of Calophyllum spp. on cancer cells

Melissa Kilus1, Nozlena Abdul Samad1*, Shaari Daud2

Abstract


Published online 09 September 2023

Moringa oleifera's Effect on Colorectal Cancer

Rolla Al-Shalabi 1,2, Nozlena abdul samad 1*, Lim Vuanghao 1, Ibrahim Al Deeb 2, Julia Joseph 1

The therapeutic benefit of Moringa plant in cancer treatment

Abstract


Published online 03 October 2023

Unlocking Nature’s Treasure Trove: Exploring Microorganisms for Novel Bioactives

Tasbir Amin1, Abu Bakar Karim1, Israk Iram Oyshe1, Amana Hossain1, Tafsir karim1, Jinath Sultana Jime1, Nayeema Bulbul1, Md. Asaduzzaman Shishir2, Ashrafus Safa3, Md. Fakruddin1*

Abstract


Published online 16 October 2023

Optimizing The Protocol For Extraction Of Bioactive Components From Hibiscus Sabdariffa With Potent Antioxidant Activity

Nur Royhaila Mohamad *1, Farrah Payyadhah Borhan 2, Mohd Shahrizi Razali 3, Roswanira Abdul Wahab 4

Utilize statistical methods to determine which different variables impact the response to the extraction of roselle.

Abstract


Published online 21 October 2023

Antioxidant Potential of Calophyllum gracilentum: A Study on Total Phenolic Content, Total Flavonoid Content, and Free Radical Scavenging Activities

Nurr Maria Ulfa Seruji1, Vivien Jong Yi Mian1*, Nor Hisam Zamakshari2, Thiruventhan Karunakaran3, Lee Feng Koo4, Wong Tze Jin4, Chan Thye Huat5

Study of potential Therapeutic activity of Calophyllum herb.

Abstract


Published online 22 October 2023

The way of cholesterol in atherogenesis: from the main enemy to complex biomarkers

Anastasia V. Poznyak 1*, Victoria A. Khotina 2, Mikhail A. Popov 3, Alexander D. Zhuravlev 2, Vasily N. Sukhorukov 2, Alexander N. Orekhov 2*

Abstract


Published online 02 November 2023

Knowledge and Self-Management Practice Among Diabetic Patients from the Urban Areas in Bangladesh

Md. Jubayer Hossain1, Syeda Tasneem Towhid1,2* , Sumona Akter1 , Muhibullah Shahjahan1, Tilottoma Roy1, Bithi Akter1, Tanjum Ahmed Nodee1

Abstract


Published online 11 November 2023

Inhibitory Activity of Enzyme Α-Glucosidase Ethanol Extract Combination Of Mareme Plant (Glochidion arborescens (Müll. Arg.) Boerl.) Leaves And  Sala Plant (Cynometra ramiflora Linn) Leaves

Haryoto1*, Alysa Vivi Arnida1, Peni Indrayudha1, Cita Hanif Muflihah1, Khong Heng Yen2

Mareme and Sala leaves mix may be a strong blood sugar blocker, but it contains useful chemicals for potential medical research.

Abstract


Published online 12 November 2023

Stromal Interaction Molecule-1 (STIM1): Orchestrating Calcium Signaling in Cancer and Hematologic Malignancies

Rabiatul Basria S. M. N. Mydin1, Adam Azlan1, Eman Salem Saeed Algariri,1 Nur Azuar Abdul Rahim2,3, Emmanuel Jairaj Moses1, Narazah Mohd Yusoff1

Abstract


Published online 14 November 2023

Antiangiogenic and Anticancer Potential of Supercritical Fluid Extracts from Nutmeg Seeds; In vitro, Ex vivo and In silico studies

Sawsan S. Al-Rawi1*, Ahmad Hamdy Ibrahim2, Marthad A. Hamde3, Dinesh Babu4, Mansoureh Nazari5, Mohd Omar Ab Kadir6, Aman Shah Abdul Majid7, Amin Malik Shah8

Abstract


Published online 23 November 2023

Comparative Analysis of Epstein-Barr Virus EBNA-2 Sequence Variation in Nasopharyngeal Carcinoma and Other EBV-Related Tumors

Lee Wei Zheng1,2, Rabiatul Basria S. M. N. Mydin1*, Adam Azlan1,5 and Muhamad Yusri Musa3,4

Abstract


Published online 24 November 2023

Hepatitis C and Atherosclerosis: Inflammatory Interplay

Anastasia V. Poznyak 1*, Ludmila V Nedosugova 2, Vasily N. Sukhorukov 3, Alexandra A. Melnichenko 3, Elizaveta M. Pleshko 3 and Alexander N. Orekhov 3

A review of the relationship between HCV infection, inflammation, and cardiovascular pathologies.

Abstract


Published online 24 November 2023

Effect of Plumbago zeylanica on Analgesia and Arthritis

Subasini Uthirapathy1*

The inhibition activity of PZ on carrageenan-induced arthritis, humoral and cellular immunity, and pain and inflammation.

Abstract


Published online 27 November 2023

Pomegranate Juice Attenuates Anti-ulcer in Indomethacin-induced Peptic Ulcer

Ali Omar Yaseen 1, Payam Jamal Muhamed 1, Hacer Haltas 1 , Subasini Uthirapathy 1*

Study on using pomegranate juice supplements to treat ulcers caused by pain medications.

Abstract


Published online 27 November 2023

Characterization of Essential Oil Composition of Syzygium aromaticum Linn. (Clove) by GC-MS and Evaluation of its Antioxidant Activity

Javed Ahamad 1*

The study of Clove essential oil as an antioxidant drug.

Abstract


Published online 05 December 2023

Gymnemagenin a Promising Drug Candidate for Management of Hyperglycemia: In-Vitro and In-Vivo Study

Javed Ahamad1, Saima Amin2, Kamran J Naquvi1, Showkat R Mir3*

Study of Gymnema sylvestre plant for the treatment and management of diabetes.

Abstract


Published online 08 December 2023

Current Perspective on Pesticides: Their Classification, Behaviour, Potential Use and Toxic Effects

Adil Ahamad1*, Javed Ahamad2, Mohd. Javed Naim2

Monitoring the use of pesticide and analyzing their acceptable levels for human health.

Abstract


Published online 04 December 2023

Drug Repositioning and Response Detection Based on Randomized Control Trials for Cancer Treatment - A Review

Aman Chandrakar 1, Chetan Kumar Sonkar 2

The cancer treatment will be accelerated through drug repositioning.

Abstract


Published online 01 January 2024

Black Soldier Fly Larvae Feed with Fermented Bamboo Culms Enriched with Lactic Acid Bacteria

Nurul Azila Abdul Razak 1, Ang Chung Huap 1*, Vivien Jong Yi Mian 1, Siti Nor Ain Seri Masran 2

The study of plant-based protein source as  the nutrition of Black soldier fly

Abstract


Published online 05 December 2023

A Review of Potential Roles for Micro RNAs as Drugs Sensitivity Biomarkers in Breast Cancer

Monika Barsagade 1*, Ravi kishore Agrawal 2*

The role of miR-202's in discovering biomarkers for early diagnosis and improving therapeutic strategies for breast cancer.

Abstract


Published online 06 December 2023

Evaluation of Cardiac Reserve Using Echocardiography for The Detection of Mild Cardiac Dysfunction in Mice - A Review

Sanjay Kumar Mire 1, Deepak Kumar Sahu 2

Echocardiography-based strain imaging offers early detection of cardiac abnormalities, treatment, and research strategy. 

Abstract


Published online 06 January 2024

Determination of Active Biomarkers and the Antioxidant and Antibacterial Potential of Standardized Zygophyllum spp Extract

Mostafa Alamholo 1

Identification of active compounds in medicinal plants to control resistant bacteria

Abstract


Published online 07 January 2024

Evolution of Genes and Transcripts Modifies Drug Sensitivity in Cancer Cell Lines - A Review

Krishna Sahu 1, Urvashi Jain 2

Dynamic genomic and transcriptomic evolutionary modeling guides cancer genetics, transforming treatment by predicting drug sensitivity in genomics.

Abstract


Published online 07 December 2023

Discovering Novel and Old Drug Targets in Oral Cancer Stem Cells Using bio-inspired methods - A Review

Vijay Kumar Jaiswal 1, Mahendra Kumar Verma 2

Evolutionary Computation Network for Drug Repositioning reveals oral cancer stem cells, informing targeted therapies for treatment.

Abstract


Published online 07 December 2023

Impedimetric Sensor Aided by Polydopamine Nanoparticles for Label-Free Detection of Breast Cancer Cells - A Review

Bhuneshwari Dewangan 1, Naina Bhoyar 2

 

A review of polydopamine sensor in breast cancer diagnosis.

Abstract


Published online 08 December 2023

Analyzing The Risks, Benefits, and Therapeutic Potential of Cannabis And Cannabinoids in Tumor Therapy - A Review

Poorti Sharma 1*, Lukeshwari Sahu 1

Study explores Cannabis use by metastatic tumor patients, analyzing active components, addressing gaps in research, and promoting informed medical guidance.

Abstract


Published online 08 December 2023

Review on Health And Quality of Life of Elderly People: A Meta-Analysis from The Medical and Health Sciences

Ashish Agarwal 1*, Sachin Pradhan 2

An IoT-based system enhancing elderly care, emphasizing QOL, independence, and support, aiding healthcare development for seniors' well-being.

Abstract


Published online 08 December 2023

The Clinical, Histological, and Immunohistochemical Features of Bone Metastases - A Review

Ragini Patel 1*, Yogendra Sahu 2

A deep learning model to trace bone metastasis origins, addressing challenges in diagnosis and emphasizing therapeutic implications and monitoring.

Abstract


Published online 12 December 2023

Hydrophobin-Coated Noisomes as Drug Carriers in Lung Cancer Cells - A Review

Srishti Namdeo 1, Chandrapratap Dhimar 2

Targeted nanoparticle delivery to Lung Cancer Cells, using hydrophobin-coated niosomes, addressing multidrug resistance, and enhancing treatment efficacy.

Abstract


Published online 14 December 2023

Predictive Modeling of The Chronic Pain-Induced Depression in Old Adults Based on Music Intervention

Birendra Kumar Sahu 1, Chiranjeev Singh 2

This research addresses the prevalent issue of chronic pain in older adults, proposing a novel Predicting Chronic Pain-based Music Intervention model for personalized, effective treatment, showcasing promising results for mental well-being improvement.

Abstract


Published online 14 December 2023

Analysis of Semi-Rural and Urban Hypertension Prevalence Using WHO Measures

Sumit Kumar Agrawal 1, Tripti Dewangan 2

Guiding a tailored intervention and strategy to advance global hypertension management

Abstract


Published online 17 December 2023

Menopause-Related Insomnia, Cognitive, Behavioral, and Mindfulness-Based Treatments

Venu Anand Das 1, Jitendra Sinha 2

The study explores challenges in treating menopausal symptoms, introducing the Menopause-based Treatment Study Framework (MTSF) for more effective and enduring resolution.

Abstract


Published online 17 December 2023

Epidermal Growth Factor Receptor and Double-Imprinted Nanoparticles for Targeted Cancer Drug Delivery - A Review

Lakhan Lal Kashyap 1, Harish Jaiswal 2

A targeted drug delivery approach, using double-imprinted nanoparticles and EGFR-SVM, to enhance anticancer drug effectiveness selectively in tumor cells.

Abstract


Published online 19 December 2023

Identifying Thyroid Dysfunction Using Standard Laboratory Testings – A Systematic Review

Vinay Jaiswal 1, Prachi Gurudiwan 2

A ML-TDI model for thyroid dysfunction identification, addressing underdiagnosis challenges and emphasizing the importance of comprehensive assessment in care.

Abstract


Published online 21 December 2023

Screening for Oral Cancer Using Brush Biopsies and DNA Image Cytometry - A Review

Pranjali Verma 1,  Shikha Kumari Rajak 2

A non-invasive DNAIC-DCNN for accurate oral cancer diagnosis, offering targeted medications for effective treatment.

Abstract


Published online 21 December 2023

The Effect of Naturally Occurring Dietary Chemicals and Food-Borne Mycotoxins on DNA Methylation and Cancer - A Review

Moniza Nurez Khan 1, Naresh Chandravanshi 2

The critical impact of Food-Borne Mycotoxins (FBM) and Artificial Light At Night (ALAN) on DNA methylation, influencing cancer risk and disease outcomes.

Abstract


Published online 22 December 2023

Analyzing the Influence of Initial Diagnosis on Interpersonal Problem Trajectories in Residential Treatment for Eating Disorders - A Review

Hemlata Dewangan 1, Neetish  Kumar 2

A systematic review of post-residential treatment outcome for eating disorders

Abstract


Published online 25 December 2023

Physical Activity Correlates With The Aging Process in Seniors Broadly - A Review

Bhuneshwari Dewangan 1, Naina Bhoyar 2

A review of a correlation between physical activity, life satisfaction, and aging in the senior age group with Internet of Things (IoT) based Physical Activities (IoT-PA) model

Abstract


Published online 29 December 2023

Brain-Computer Interfaces Can Significantly Improve The Quality of Life for Aged People - A Review

Sanjay Kumar Mire 1, Deepak Kumar Sahu 2

A non-invasive Brain-Computer Interfaces (BCIs) and IoT-based Smart Home Technology can enhance memory, focus, and aged people's quality of life.

Abstract


Published online 08 January 2024

Gut-Brain Connection; IBS linked to Anxiety, Quality of Life, and Academic Performance in Undergraduate Students

Mohamed Sadeq Al-Ibrahim *1, Ahmad Hamdy Ibrahim 2, Sawsan S. Al- Rawi *3, Bayram Dawod Ahmed 4, Nalan Linda Fraim 5

Chronic stress affects many physiological processes including immunity and angiogenesis. IBS impacts anxiety, quality of life, and academic performance of undergraduate students.  

Abstract


Published online 08 January 2024

A Review of Dipeptidyl Peptidase-4 (DPP-4) and its potential synthetic derivatives in the management of Diabetes Mellitus

Mohd. Javed Naim 1

To establish potential DPP-4 inhibitors. 

Abstract


Published online 11 January 2024

Polycystic Ovarian Syndrome: An Overview with Special Consideration to Its Oral and Pediatric Clinical Manifestations

Zeba Saleem 1, Abiha Ahmad Khan *1, Syeda Aamena Naaz 1 and Mohd. Javed Naim 2

Highlighting the oral and pediatric manifestation of PCOS. 

Abstract


Published online 12 January 2024

An In-Depth Analysis of Microorganisms Linked to Various Forms of Hospital-Acquired Infections: A Systematic Review

Nadirah Yusof 1,  Rabiatul Basria S. M. N. Mydin 1,2*, Chandrarohini Saravanan 2,3,4, Nor Hazliana Harun 2,5, Siti Salmah Noordin 5

The study aims to provide a detailed understanding of the microorganisms involved in different types of HAIs, such as surgical site infections, urinary tract infections, bloodstream infections, and respiratory tract infections.

Abstract


Published online 12 January 2024

Platelet Implication in Atherosclerosis Pathogenesis

Anastasia V. Poznyak 1*, Varvara A. Orekhova 1, Vasily N. Sukhorukov 1, Alexandra A. Melnichenko 2, Elizaveta M. Pleshko 2, Alexander N. Orekhov 1

Platelets' vital role in health, thrombosis, atherosclerosis; therapy's ongoing clarification.

Abstract


Published online 15 January 2024

Maternal Hypercholesterolemia is a Significant Risk Factor for Atherogenesis – A Systematic Review

Anastasia V. Poznyak 1*, Victoria A. Khotina 2, Vasily N. Sukhorukov 2, Nikolay Sadykhov 2, Anton Y Postnov 2, and Alexander N. Orekhov 2*

Maternal hypercholesterolemia during pregnancy influences fetal development, leading to lasting atherosclerotic changes, emphasizing preventive strategies to reduce future cardiovascular disease burdens.

Abstract


Published online 16 January 2024

An Educational Intervention to Improve Adverse Drug Reactions Reporting Among Healthcare Practitioners in Selected Pediatric Hospitals in Iraq

Bootan A. Salih 1,*, Omer Q. Allela 2, Raad A Kaskoos 3, Javed Ahamad 4

The main goal of the study is to design an intervention program to increase knowledge attitude and practice of healthcare practitioners towards pharmacovigilance.

Abstract


Published online 17 January 2024

Innovative Piperidine-Catalyzation in Protecting Carbonyl Compounds with Implications for Angiogenesis and Inflammation

Mukhlif Mohsin Slaihim 1*, Luay Ali Dhahi 1, Abeer Hussein Ali 1

Introduced piperidine-catalyzed protection in aldehydes, guiding anti-cancer compound optimization.

Abstract


Published online 18 January 2024

Effect of Toll-Like Receptor 9 (TLR9) in Breast Cancer Risk, Along with Hormonal Effects in Patients Receiving Radiotherapy

Asra'a Adnan Abdul-Jalil 1, Marrib N. Rasheed 2, Rana H. Hamoode 3

TLR9 rs187084 polymorphisms crucial in Iraqi women's breast cancer susceptibility.

Abstract


Published online 19 January 2024

Optimizing Fast-Dissolving Tablets of Ketotifen: Impact of Sodium Bicarbonate and Citric Acid in Formulation and Evaluation

Rozhan Arif 1, Sharad Visht 1*, Ali Omar 1, Sana Sirwan Salih 1

Formulating ketotifen fast-dissolving tablets (FDT) tackled poor bioavailability challenges, emphasizing sodium bicarbonate's pivotal role for rapid tablet disintegration, highlighting FDT viability for asthmatic treatment.

Abstract


Published online 20 January 2024

Significance of Serum Biomarkers in Early Diagnosis of Hepatocellular Carcinoma in Patients with Fisher Groups

Tufael 1, Auditi Kar 2, Vijay Jagdish Upadhye 3*, Amith Dutta 4, Md Royhanur Islam 5, Abdus Sattar 6, Md. Eunus Ali 7, Julakha Akter 8, Kaniz Fatima Bari 9, Md. Tahsin Salam 10, Palash Chandra Banik 11, Md Shamsuddin Sultan Khan 12, Atiqur Rahman Sunny 13*

The research addresses a crucial gap by linking the unique lifestyle and stressors in fisher groups to hepatocellular carcinoma.

Abstract


Published online 20 January 2024

Advancing Therapeutic Efficacy of Star Anise Oil with (Illicium verum) Nano-Emulsion Formulation

Sharad Visht 1, Sana Sirwan Salih 1, Belan Azad Ibrahim 1, Daniah Issa Ismael 1, Serwa Falah Abdalwaheed 1, Omji Porwal 1

Star anise oil-based nano-emulsions' extraction, purification, and formulation processes to improve therapeutic efficacy of drug substances

Abstract


Published online 20 January 2024

A Review of Healing Potential of Indian Flora: An Ethnopharmacological Evidence of Wound Healing Activity

Rasmita Jena 1,2, Durga Madhab Kar 1*, Sovan Pattanaik 1, Bhisma Narayan Ratha 3

This review emphasizes the rich potential in traditional practices, offering valuable insights and solutions to current healing challenges.

Abstract


Published online 21 January 2024

Renal and Hepatic Toxicity of Alpha-Cypermethrine Pesticide Used on Agricultural  Farmers Living Closed to Tigris river, Iraq

Sarhan Rashid Sarhan 1*,   Mohammed H.M. Merah 2

ALP, ALT and AST enzymes increased significantly when directly exposed to this pesticide as a result of its effect on kidney and liver functions.

Abstract


Published online 21 January 2024

Therapeutic Effects of Esomeprazole, Curcumin, Chitosan, and Curcumin-Chitosan Mixture on Ethanol-Induced Gastric Ulcer in Female Rats

Jenan Mahdi Jawad Al-kawaz 1*, Fakhir Magtoof Al-Zubaidy 2**, Hussein Jassim Obaid Al -Harbi 1***

Evaluate the healing effects of esomeprazole, curcumin, chitosan, and a curcumin-chitosan mixture on gastric injuries induced by ethanol in rats.

Abstract


Published online 21 January 2024

Synthesis And In-Silico Anti-Cancer Potential of N-Aryl-Keto-Nitrone As A Spin Adducts

Rita S. Adam 1*

Advancing spin trapping chemistry through the introduction of effective linear keto-nitrones, expanding applications and refining practical use.

Abstract


Published online 22 January 2024

Effect of Metformin and Vitamin D Supplementation on Metabolic and Hormonal Profiles in Polycystic Ovary Syndrome Women: A Follow-Up Study

Zainab Nur-Eldeen Aziz 1*, Basil O. Saleh 1

Positive Impacts of Metformin and Vitamin D Supplementation on Polycystic ovary syndrome (PCOS) Women

Abstract


Published online 22 January 2024

Anti-Cancer Study of Carvacrol in Hypoxic-Induced Colorectal Cancer Cell

Aumaima Tariq Abed 1,2* ,  Ahmed MH AlMudhafar 1 , and Najah R Hadi 1

Effect of carvacrol on proliferation and migration of hypoxic SW480 cancer cells

Abstract


Published online 22 January 2024

Effect of Steroid Treatment on Tissue Damage Markers in Diabetic Patients

Mohammed Shakir Ali 1*, Ali Al-Shammari 1, Qutaiba A. Ismael 1, Obaida Amer Imran 1, Mohammed H. Al-Bayati 1

This research showed how diabetes and steroids worsen effects, providing a better understanding of the pathophysiology processes.

Abstract


Published online 22 January 2024

Synthesis, Characterization and In Vitro Anti-cancer  Properties of Cationic Gemini Surfactants with Alkyl Chains in Human Breast Cancer

Anwar Shalan F. 1*, Samah Hussein Kadhim 1

Anti-cancer activity of Gemini surfactants in human breast cancer cells

Abstract


Published online 22 January 2024

Impact of Various Contraceptive Methods on Immunological Profiles in Women: A Serological Analysis in Diyala Governorate

Shaymaa Mohammed Alwan 1, Maha Falih Nazzal 2, Inaam Faisal Mohammed 3

Abstract


Published online 22 January 2024

Two Forms of C-Reactive Protein and Their Implication for Atherogenesis: Focus on Monomeric Form

Anastasia V. Poznyak 1*, Victoria A. Khotina 2, Anton Y Postnov 2, Vasily N. Sukhorukov 2, Nikolay Sadykhov 2, Alexander N. Orekhov 2*

A review on inflammatory protein in atherosclerosis progression.

Abstract


Published online 22 January 2024

Machine Learning-Based Enhanced Drug Delivery System and Its Applications – A Systematic Review

Abhijeet  Madhukar Haval 1*, Kumar Shwetabh 1, Sushree Sasmita Dash 1

Machine Learning (ML) transforms drug development, predicting drug properties, targets, interactions, and facilitating efficient exploration for researchers and pharmaceutical companies.

Abstract


Published online 23 January 2024

A Systematic Review of Advanced Approaches in Wound Healing: Simvastatin Polymeric Nanoparticles and Postbiotics Innovation

Chandrapratap Dhimar 1*, Krishna Sahu 1, Moniza Nurez Khan 1

Utilizing innovative postbiotics and Simvastatin Polymeric Nanoparticles, wound research accelerates healing, promising improved treatment with minimal inflammation.

Abstract


Published online 23 January 2024

A Review of Modeling Checkpoint Blockade Therapy and Therapeutic Strategies in Integrative Pharmacological Approach for Metastatic Breast Cancer

Prachi Gurudiwan 1*, Ragini Patel 1, Urvashi Jain 1

Quantitative Systems Pharmacology models immune processes in breast cancer, aiding personalized treatment by identifying biomarkers, resistance mechanisms, and therapeutic options

Abstract


Published online 23 January 2024

In vitro Antibacterial Activity of Seribu kuman Leaf (Rhinacanthus nasutus (l.) Kurz) Extracts Against Staphylococcus aureus and Pseudomonas aeruginosa

Betty Fitriyasti 1*, Siska Ferilda 2, Widia Sari 3, Muhammad Rizki Saputra 4, Heng Yen Khong 5*

Rhinacanthus nasutus extract inhibits the growth of Staphylococcus aureus and could serve as an alternative in treating infections caused by S. aureus.

 

Abstract


Published online 24 January 2024

The Characterization of Acute Myeloblastic Leukemia-M2 Cell Lines with Suppressed Stromal Interaction Molecule 1 (STIM1) and its Impact on Calcium/Reactive Oxygen Species Profiles

Eman Salem Algariri 1,2, Rabiatul Basria S. M. N. Mydin 1*, Emmanuel Jairaj Moses 1, Nur Arzuar Abdul Rahim 3, Narazah Mohd Yusoff 3

STIM1's potential role in promoting AML-M2 cell survival by regulating calcium/ROS interactions, as well as KRAS/MAPK and Akt-related pathways

Abstract


Published online 24 January 2024

A Comprehensive Review on Cardiovascular Disease Detection, Risk Assessment, And Treatment Using A Network Pharmacology Model

Vijay Kumar Jaiswal 1*, Monika Barsagade 1, Jitendra Sinha 1

Contribution to advancing diagnostic methods, proposing innovative treatment approaches, and demonstrating the effectiveness of pharmacist-led preventive strategies for improving population health, reducing the economic burden of cardiovascular diseases, and showing more personalized and mechanism-based approaches in healthcare.

Abstract


Published online 24 January 2024

Advancements in Ocular Vascularization Analysis Using Deep Learning Techniques – A Systematic Review

F Rahman 1*, Akanksha Mishra 1, Sushree Sasmita Dash 1

This review shows an advanced machine learning method for efficient segmentation and classification of blood vessels in medical images, revolutionizing diagnostic precision.

Abstract


Published online 25 January 2024

Advances of AI-driven Drug Design and Discovery in Pharmaceuticals - Review

Dev Ras Pandey 1*, Sushree Sasmita Dash 1, Akanksha Mishra 1

The application of AI in pharmaceuticals holds the promise of personalized therapies, streamlined production, and improved market strategies, making it an indispensable tool for the future of drug development.

Abstract


Published online 25 January 2024

Smart Wound Monitoring and Healing Assessment System With Deep Learning Methods - A Systematic Review

Abhijeet  Madhukar Haval 1*, Akanksha Mishra 1, Sushree Sasmita Dash 1

Wound features impact healing; indicators like temperature, oxygen levels, and moisture influence the process. This review shows and effective at-home wound monitoring with biosensors.

Abstract


Published online 26 January 2024

Advances in Image Processing Methods for Breast Cancer Diagnosis and Classification Using A Hybrid Machine Learning – A Systematic Review

Priya Vij 1, Sushree Sasmita Dash 1, Akanksha Mishra 1

Advanced integration of deep learning (AlexNet) and SVM-RBF for breast cancer diagnosis surpasses existing models, ensuring precise and reliable early detection.

Abstract


Published online 26 January 2024

A Pharmacy System Integrated with A Machine Learning Algorithm for Cardiovascular Disease Prediction

Kumar Shwetabh 1*, F Rahman 1, Sushree Sasmita Dash 1

The review explores an inclusive ML structure, vital for efficient CVD forecasting. The proposed model showcases superior accuracy, emphasizing the need for comprehensive predictive algorithms in cardiovascular health research.

Abstract


Published online 05 February 2024

Vitamin D Deficiency As A Contributor To Atherosclerosis Development – A Review

Anastasia V. Poznyak 1*, Victoria A. Khotina 2, Alexandra A. Melnichenko 2, Victor Y Glanz 2, Vasily N. Sukhorukov 2, and Alexander N. Orekhov 2*

Vitamin D deficiency and cardiovascular diseases, explores role in inflammation, oxidative stress, and vascular calcification

Abstract


Published online 08 February 2024

Repurposing Drugs for Overcoming Therapy Resistance in Colon Cancer – A Review

Mahdi Darvishi 1, Amir Mohammad Chekeni 2, Mohammad Fazelhosseini 1, Zeenat Iqbal 3*, Mohd Aamir Mirza 3*, Perwez Alam 4, Ali Akhtar 4, Mohd. Aslam 5, Esra Tariq Anwer Bayrakdar 5

Oncology research seeks new therapies for aggressive CRC, utilizing repurposed drugs for accelerated and safer treatment approaches.

Abstract


Published online 09 February 2024

A Review of 3d Printing Model of New Blood Vessel Formation For Pharmaceutical Applications

Nidhi Mishra 1*, Priya Vij 1, Akanksha Mishra 1

Innovative synthetic blood vessels offer promising solutions for cardiovascular diseases, providing safer, more accessible treatments for aging populations

Abstract


Published online 09 February 2024

Efficient Removal of Acetamiprid Pesticide Using Date Core-Derived Activated Carbon and Korai Clay As A Good Sorbent

Huda Azhar Fadel 1*,  Lekaa Hussein Khdaim 1

Iraqi date core-derived activated carbon effectively removes acetamiprid pesticide, crucial for combating water pollution, supported by comprehensive adsorption studies.

Abstract


Published online 12 February 2024

A Double-blind, Randomized Clinical Trial Study of Plantago major l. Syrup on Menorrhagia

Sajedeh Ghasempour 1, Mohsen Naseri 2, Fatemeh Alijaniha 2, Yasin Karimi 3, Anoushirvan Kazemnejad 4, Shahrzad Hadavand 5 , Seyedeh Fatemeh Jafari 2

The study highlights Plantago major's potential to reduce menorrhagia severity and duration, offering a promising complementary treatment with minimal side effects.

Abstract


Published online 13 February 2024

Understanding and Combatting COVID-19: Insights from Clinical Characteristics and Management Strategies

Bala Krishnan A 1, Vigneshwaran V 1, Tharani Kumar L 1, M. Shagar Banu 1

Timely analysis is crucial for understanding and combating global health crises like COVID-19 effectively

Abstract


Published online 13 February 2024

Concerning Fungal Coinfections in COVID-19: Risks, Types, and Prevention – A Review

Bala Krishnan A  1, Vinoth Kumar K K 1, Tharani Kumar L 1, M. Shajini G Inbakani 1

The review highlights the alarming rise of fungal infections like Mucormycosis among COVID-19 patients, necessitating prompt diagnosis and care to prevent fatalities.

Abstract


Published online 13 February 2024

Unprecedented Rise of Mucormycosis in COVID-19 Patients: Urgent Need for Protocol Adaptation and Awareness in India – A Review

Nithya A 1, Vinoth S V 1, Ashok Kumar M 1, Sindhu T 1

Mucormycosis in COVID-19 patients in India necessitates urgent updates in treatment protocols and public awareness

Abstract


Published online 14 February 2024

Navigating COVID-19 Treatment: CT Scans, Steroids, and Medical Practice Challenges in India

Jayanthi E 1, C. Elayaraja 2, Priyadharshini S 2, Ashok kumar M 2

The review highlights India's struggle with COVID-19, emphasizing the need for tailored treatments amid rising cases, cautioning against unnecessary tests and misuse of medications.

Abstract


Published online 14 February 2024

In vitro Cytotoxicity and Apoptotic Activity of Aquous, Chloroform and Methanol Extracts of Kiwi Fruit Actinidia deliciosa in MCF-7 cells

Kartheeswari 1, Archana C 1, Anupreyaa K 1, Saranya M 2

Assessment of A. deliciosa extracts' anticancer potential on MCF-7 cells offers insights for natural cancer medication development

Abstract


Published online 15 February 2024

Impact of Dapagliflozin on Atherosclerosis through Inflammation and Oxidative Pathways

Zainab Abdlkadhim Aboshnin 1*, Safa Azhar Razzaq 1, Zahraa Ibraheim Jawad Shubber 2

Atherosclerotic patients need therapies targeting inflammation and oxidation. This study supports Dapagliflozin's use for clinical benefits in atherosclerosis.

Abstract


Published online 15 February 2024

Association Between Low Bone Mineral Density in Hemophilia Patients and Musculoskeletal Function Impairments

Rasha Ibrahim Salman 1* , Khalid Mahdi Salih 1*, Nidal Karim Al-Rahal 2*

Hemophilia patients with low bone density (BMD) face higher risk with severe limitation of movement (LOM) and viral infections.

Abstract


Published online 16 February 2024

The Analysis of Hypertension Knowledge in Adults in Telafer City: Implications for Health Education and Intervention

 Mohammed Qassim Baktash 1* , Ali Ismael Sulaiman 1

Understanding hypertension in Telafer City adults is vital for preventing problems, guiding interventions, and managing the disease effectively

Abstract


Published online 17 February 2024

The Analysis of Hematological Parameters CBC, ABO, NLR, and APTT and Its Implications on Haemophilic Patients with Low Bone Mineral Density

Rasha Ibrahim Salman 1* , Khalid Mahdi Salih 1, Nidal Karim Al-Rahal 2

The study determined a high prevalence of low bone mineral density in hemophilic patients, associated with elevated NLR and prolonged APTT.

Abstract


Published online 17 February 2024

Efficacy of Paromomycin-Conjugated Nano Chitosan in Treating Entamoeba histolytica Infection in Mice

Hajar Falih Hishan Aldali 1*, Shatha Khudiar Abbas 1, Ahmed Naji Abd 1

Entamoeba histolytica causes widespread amebiasis. Chitosan-paromomycin nanoconjugates effectively treated infected mice, reducing liver enzyme levels, showing promising therapeutic potential.

Abstract


Published online 17 February 2024

Anti-Cancer Activity of Allium Ascalonicum Ethanol Extract Against Human Hepatocellular Carcinoma Cell Line (HepG-2)

Geetha N B 1*, Chintala Venkatesh 1, Suresh M 1, Manikandan S 2

Allium ascalonicum might be a safer, more effective alternative to toxic chemotherapy for combating cancer with targeted potency.

Abstract


Published online 18 February 2024

In vitro Anti-cancer Activity of Methanol Extracts of Kiwi Fruit, Actinidia deliciosa in HCT-119 Cells

Geetha N B 1, Priya R 1, Weslin D 1, Ashmi Christus A T 2

The study of anti-cancer properties of Actinidia deliciosa methanol extract in Colorectal cancer as effective treatments.

Abstract


Published online 18 February 2024

Green Fungus Challenges in Post-COVID Health Landscape

Jeha J 1, Sudha S 1, Geetha N B 1, Benitta Sherine S 2

This review provides Green Fungus challenge in post-COVID situation. Early detection, hygiene, and research are imperative.

Abstract


Published online 18 February 2024

Diagnosis of Chronic Brucellosis with Interferon-Gamma Quantification

Sarah Yahya Abdullah 1, Yasir Mufeed Abdulateef 2*, Sawsan Qahtan Taha Al-Quhli 3

This study showed the improvement of brucellosis diagnosis using interferon-gamma for better detection in chronic cases

Abstract


Published online 19 February 2024

Epidemiological Analysis of Hepatitis B and C Viruses in Fallujah for Health Intervention and Disease Control

Ahmed Saadi khlaf 1*, Asif Hasan Abdulrazaq 2, Nawar Bahaa Abdulsahib 3, Manaf Akram Ismaell 3, Mustafa Asif Hasan 3

Investigating Hepatitis B and C in Fallujah revealed higher prevalence among males, aiding targeted interventions and public health initiatives.

Abstract


Published online 19 February 2024

A study of Enhancing Fencing Skills with The Impact of Special Exercises on Kinetic Response and Attack Accuracy among Young Foil Players

Reem Mohammed Abdel Wahhab 1*

This study showed an improved exercise enhancing kinetic response, vital for fencing to optimize athletes' and their healthy performance.

Abstract


Published online 19 February 2024

Determination of Demographic Liver Health with Giardia lambila Infection Analysis in Diyala

Noora Dhyaaldain Abed 1*, Shahad Abdul Jabbar Mohammed 2*

This study analyzed the Giardia infection as early detection for liver health intervention.

Abstract


Published online 20 February 2024

Salmonella Biofilms And Antibiotic Resistance Determination From Different Patient Types

Mariam Ayad Abd 1*, Sawsan Q. T. Al-Quhli 2, Mahir Ali Jassim 3

This study discussed important information about antibiotic resistance and how harmful Salmonella bacteria are in Iraqi patients, helping to plan better public health measures.

Abstract


Published online 20 February 2024

Cumin Extract Alters The Histology of Kidney and Duodenum in Adult Rabbit

Hussein B. Mahmood 1*,  Naseer  A. Al-Arubaye 1, Walaa F. Obead 1

This study showed the histological alterations of the kidney and duodenum due to excessive use of cumin.

Abstract


Published online 20 February 2024

Treatment of High-Fat Diet-Induced Obesity and Insulin Resistance Using Rose Flowers (Rosa damascena) in Rat

Kamran Javed Naquvi 1*, Javed Ahamad 1

Rosa damascena petals reduce obesity-related markers and insulin resistance. This is a natural agent for metabolic health improvement and weight management.

Abstract


The Most Read ranking is based on the number of downloads in the last 60 days from papers published on the emanresearch PUBLISHING website within the last 12 months. Usage statistics are updated daily.

SCImago Journal & Country Rank

Committee on Publication Ethics


Submit Article

Use the online submission system to send us your manuscript.


Call for Papers

We are seeking Contributions for a special issue.  More.


Best Paper Award

Authors are awarded for Best Paper for this Journal Annually


Advertisement