A Rare Case of Familial Adenomatous Polyposis

Lakshmi K, Dinesh K, Bindu D, Sharanya K

The diagnosis of FAP is based on the detection of more than 100 adenomatous Colon polyps. We had a case of FAP in a 37-year-old man with history of abdominal pain and bleeding per rectum for 6 months.

Abstract

Familial adenomatous polyposis (FAP) is rare one.1 of colorectal cancer associated with FAP. It is a precancerous condition and is having 100 malignant potential. FAP is present in younger age group, so proper screening and prophylactic total colectomy is required. FAP is an autosomal dominant disease that results from mutation in the adenomatous polyposis coli (APC) gene located on chromosome5q21-22. One third of all cases of FAP have nil family history of FAP, and these cases are thought to be caused by a new germ-line mutation. The diagnosis of FAP is based on the detection of more than 100 adenomatous Colon polyps. We had a case of FAP in a 37-year-old man with history of abdominal pain and bleeding per rectum for 6 months.

Keyword: Familial Adenomatous Polyposis, Colonoscopy, Sigmoidoscopy and Colorectal Cancer.

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