Exploring the Complex Interactions Between COVID-19, Oxidative Stress, and Cancer Susceptibility
Nurhani Jamali1, Rabiatul Basria S. M. N. Mydin1,2*, Nur Hakimah Abu Mansor2
Journal of Angiotherapy 8(6) 1-5 https://doi.org/10.25163/angiotherapy.869613
Submitted: 29 March 2024 Revised: 10 June 2024 Published: 15 June 2024
Abstract
The emergence of COVID-19 as a global pandemic has posed significant challenges, impacting millions worldwide and spurring urgent research into its pathogenesis and associated complications. This review examines the complex relationship between COVID-19, oxidative stress, and cancer susceptibility. COVID-19, caused by SARS-CoV-2, affects multiple organ systems and presents a wide range of symptoms with serious consequences. Oxidative stress, characterized by an imbalance between prooxidants and antioxidants, plays a crucial role in the pathogenesis of COVID-19, potentially worsening disease severity and influencing patient outcomes. The interaction between oxidative stress, inflammation, and COVID-19 progression is intricate, with oxidative stress biomarkers emerging as key contributors to disease severity. Furthermore, post-COVID-19 complications, including increased cancer risks, highlight the long-term effects of SARS-CoV-2 infection. Understanding the complex dynamics of oxidative stress, inflammation, and cancer susceptibility in the context of COVID-19 is essential for developing comprehensive healthcare strategies and reducing the global disease burden.
Keywords: COVID-19, Oxidative stress, SARS-CoV-2, Cancer, Disease, Virus Infection, Human Health
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