EMAN RESEARCH PUBLISHING | Journal | <p>Study of Demographic and Clinical Profile of Children with Indigenous Camphor Exposure Presenting at A Tertiary Care Centre</p>
Inflammation Cancer Angiogenesis Biology and Therapeutics | Impact 0.1 (CiteScore) | Online ISSN  2207-872X
RESEARCH ARTICLE   (Open Access)

Study of Demographic and Clinical Profile of Children with Indigenous Camphor Exposure Presenting at A Tertiary Care Centre

Jayakanthan S, Manimaran R, Sathyanarayanan M, Bharathi Raja K

+ Author Affiliations

Journal of Angiotherapy 5(2) https://doi.org/10.25163/angiotherapy.52121542819191221

Submitted: 28 November 2021  Revised: 08 December 2021  Published: 19 December 2021 

Camphor poisoning should be considered as a cause of seizure in otherwise healthy children and parents should be asked regarding possible ingestion of camphor products in the preceding few hours.

Abstract


Background: Small children have a tendency to put everything in the mouth; hence, poisoning due to accidental ingestion of commonly available household toxic substances is quite common in infants and small children. The aim of this retrospective study was to describe the demographic and clinical profile of children treated following exposure to camphor. Methods: A Retrospective descriptive study of children admitted with camphor poisoning from June 2018 to January 2020. The collected data were entered into a tabulated form, and descriptive statistical methods were used. Results: Of the 60 children studied, Male infants and toddlers were the most common victims of camphor induced illness. Oral route was the most common mode of exposure. The most common presenting symptom was symptomatic seizures of the generalised tonic clonic type (91.8%) followed by vomiting and fever. Most patients had seizure onset within 30 minutes of exposure that lasted for 5 to 10 minutes. 39% of those treated, required only a Benzodiazepines. Conclusion: Camphor causes neurological symptoms in young children and history of camphor exposure needs to be excluded in all cases of seizures. Ironically, most of them have not required long term AEDs on follow up. Neuroimaging done has no added benefit in prognosticating long term outcome in such children.

Key Words: Camphor poisoning, seizures

References


Anderson, D. L., & Topliff, A. R. (2001). Camphor and mothballs. Clinical toxicology. Philadelphia: WB Saunders, 339-342.

 

Narayan, S., & Singh, N. (2012). Camphor poisoning-An unusual cause of seizure. Medical Journal, Armed Forces India, 68(3), 252.

https://doi.org/10.1016/j.mjafi.2011.11.008

 

Matteucci, M. J. (2005). One pill can kill: assessing the potential for fatal poisonings in children. Pediatric annals, 34(12), 964-968.

https://doi.org/10.3928/0090-4481-20051201-12

 

Kohli U., Kuttiat V.S., Lodha R., Kabra S.K. (2008). Profile of childhood poisoning at a tertiary care centre in North India. Indian J Pediatr. ;75:791-794.

https://doi.org/10.1007/s12098-008-0105-7

 

Smith A.G., Margolis G. (1954). Camphor poisoning: anatomical and pharmaco-logic study; report of a fatal case; experimental investigation of protective action of barbiturate. Am J Pathol. ;30:857-869.

 

Aggarwal, A., Malhotra HS. (2008). Camphor ingestion: an unusual cause of seizures. J Assoc Physicians India.;56: 123-4.

 

Goel, A., Aggarwal, P., (2007) Camphor-a lesser-known killer. South Med J. ;100:134.

https://doi.org/10.1097/01.smj.0000254202.13518.f3

 

Manoguerra A.S., Erdman A.R., Wax P.M. (2006). Camphor Poisoning: an evidence-based practice guideline for out-of-hospital management. Clin Toxicol (Phila) ;44:357-370.

https://doi.org/10.1080/15563650600671696

Committee on Publication Ethics

Buy PDF
Full Text
Export Citation

View Dimensions


View Plumx



View Altmetric



0
Save
0
Citation
307
View
0
Share