Case of Bullous Impetigo Progressing to Staphylococcal Scalded Skin Syndrome: Case Report

Kannan N¹, Prabhu K², Jamunarani A³, Thatiparthi Stephen*⁴

The Staphylococcal Scalded Skin Syndrome especially affects infants and small children. SSSS is usually preceded by sore throat or conjunctivitis.

Abstract

Staphylococcus aureus can cause many exfoliative skin conditions. This includes conditions like Bullous Impetigo, which is localized to Staphylococcal Scalded Skin Syndrome, a life-threatening condition causing blistering of the upper layer of skin. Certain exfoliative toxins are released that blister the superficial epidermis by hydrolyzing human desmoglein 1. For example, bullous impetigo, the toxin produces blisters locally at the site of infection, whereas in cases of the scalded-skin syndrome, it circulates throughout the body, causing blisters at sites distant from the infection. The disease especially affects infants and small children. SSSS is usually preceded by sore throat or conjunctivitis.

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