Oxidative Stress: Insights into Nutrition, Psychological Stress, Environmental Exposure, and Antioxidants Roles

Iza Safany Che Hanafi ¹, Chandrarohini Saravanan ², Rabiatul Basria S. M. N. Mydin ^2*

This review discusses how oxidative stress affects our bodies due to factors like diet, stress, and environment, and how antioxidants help. Understanding this is crucial for fighting diseases like cancer and staying healthy.

Abstract

This comprehensive review describes the intricate realms of oxidative stress, examining its origins in nutrition, psychological stress, environmental exposures, and the vital roles of antioxidants. Nutritional factors, particularly macronutrients and dietary elements, play a dual role in either inducing or preventing oxidative stress, with implications for inflammation, metabolic disorders, and carcinogenesis. The exploration extends to the profound impact of psychological stress, highlighting oxidative imbalance as a "new stress" linked to various diseases, including psychiatric disorders. Environmental exposures, encompassing pollutants and UV radiation, contribute significantly to oxidative stress, emphasizing the need for a comprehensive understanding of these mechanisms. The role of endogenous and exogenous antioxidants is crucial in neutralizing free radicals and maintaining redox homeostasis. This thorough analysis provides insights into potential interventions and underscores the complex relationships between oxidative stress, antioxidants, and human health.

Keywords: Oxidative stress, reactive oxygen species, free radicals, nutritional, cancer, disease, antioxidant, dietary

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