Microbial Bioactives

Microbial Bioactives | Online ISSN 2209-2161
295
Citations
199.1k
Views
157
Articles

Microbial Bioactives

Microbial Bioactives is a peer-reviewed, open-access journal that publishes high-quality research and reviews in applied microbiology and related microbiolo

More +
Editor-in-Chief: Doblin Anak Sandai, Ph.D.

Article

Microbial Bioactives

Volume 9 Number 1 2026

Table of Contents


Reviews

(Unspecified)

Reviews |
Published online 24 May 2026 Manuscript-In-Press

Yeast-Derived Biomolecules in Green Nanotechnology: Bridging Sustainable Bioeconomy and Early-Life Antimicrobial Resistance Management

Ahmed MH AlMudhafar 1*, Najah R Hadi 1

Microbial Bioactives
Views: 100 | Downloads: 0

This study integrates sustainability and microbiome science, proposing yeast-based nanotechnology as a biocompatible strategy to address early-life antimicrobial resistance challenges.

Abstract | Full Text | Open Access Article

DOI: 10.25163/microbbioacts.9110637
  

Reviews |
Published online 14 May 2026 Manuscript-In-Press

Marine Microbial Metabolites as Bioactive Reservoirs: A Systematic Synthesis of Biosynthetic Diversity and Functional Potential

Faruk Hossain 1*

Microbial Bioactives
Views: 112 | Downloads: 0

This study reveals marine microorganisms as scalable, diverse bioactive sources while highlighting the urgent need for standardized, integrative discovery frameworks.

Abstract | Full Text | Open Access Article

DOI: 10.25163/microbbioacts.9110634
  

Reviews |
Published online 28 April 2026 Manuscript-In-Press

Marine Cyanobacteria and Beneficial Microbes for Sustainable Agriculture and Bio-Applications: A Review

Shahadat Hossain 1*, Mohd Hasan Mujahid 2, Sameera Zafar 2, Salaman Ahamad 2, Shaista Fatima 2

Microbial Bioactives
Views: 130 | Downloads: 0

Marine cyanobacteria and beneficial microbes provide eco-friendly solutions for agriculture, biotechnology, and sustainable industrial applications.

Abstract | Full Text | Open Access Article

DOI: 10.25163/microbbioacts.9110629
  

Reviews |
Published online 03 April 2026 Manuscript-In-Press

Rethinking Antimicrobial Strategies: Integrating Microbiome Modulation and Next-Generation Therapeutics to Combat Multidrug-Resistant Pathogens

Polycarpe Nkundayezu 1*

Microbial Bioactives
Views: 161 | Downloads: 0

Provides a comprehensive roadmap for novel antimicrobial strategies to combat multidrug-resistant infections and improve patient outcomes.

Abstract | Full Text | Open Access Article

DOI: 10.25163/microbbioacts.9110626
  

Reviews |
Published online 23 March 2026 Manuscript-In-Press

Marine Microbial Natural Products as a Frontier in Drug Discovery: A Systematic Review 

Zainab Nur-Eldeen Aziz 1*, Basil O. Saleh 1

Microbial Bioactives
Views: 166 | Downloads: 0

Marine microbial metabolites offer diverse chemical scaffolds for novel therapeutics addressing antibiotic resistance and emerging diseases.

Abstract | Full Text | Open Access Article

DOI: 10.25163/microbbioacts.9110625
  

Reviews |
Published online 08 March 2026 Manuscript-In-Press

Clostridioides difficile Infection: Emerging Challenges and the Rise of Microbiome-Targeted Therapeutics

Wafaa Naser Radhi 1*

Microbial Bioactives
Views: 181 | Downloads: 0

This work demonstrates that microbiome restoration is central to preventing Clostridioides difficile recurrence and improving sustainable treatment outcomes.

Abstract | Full Text | Open Access Article

DOI: 10.25163/microbbioacts.9110623
  

Reviews |
Published online 27 February 2026 Manuscript-In-Press

Soil Predatory Mites and Microbe-Mediated Biocontrol: Advancing Sustainable Pest Management in Agricultural Systems

Bulbul Shaikat 1*, Tahsin Bin Rabbani 1

Microbial Bioactives
Views: 144 | Downloads: 0

Understanding microbe-mediated predator–prey interactions enables sustainable soil pest management and resilient agroecosystems.

Abstract | Full Text | Open Access Article

DOI: 10.25163/microbbioacts.9110620
  

Agricultural and Environmental Microbiology

Reviews | Agricultural and Environmental Microbiology
Published online 16 February 2026 Manuscript-In-Press

Harnessing Plant Microbiomes for Sustainable Agriculture: Integrating Ecological Complexity, Microbial Function, and Translational Insights

Bulbul Shaikat 1, Tahsin Bin Rabbani 1, Salaman Ahamad 2

Microbial Bioactives
Views: 245 | Downloads: 0

Understanding plant microbiomes enables sustainable, eco-friendly strategies for crop protection and productivity enhancement.

Abstract | Full Text | Open Access Article

DOI: 10.25163/microbbioacts.9110616
  

Antimicrobial Drug Discovery

Reviews | Antimicrobial Drug Discovery
Published online 17 March 2026 Manuscript-In-Press

Microalgae and Cyanobacteria as Photosynthetic Microbial Factories: Taxonomy, Biochemical Potential, and Emerging Bioindustrial Applications

Mahmoud Nasser Radhi 1*, Mustafa Alaa Abbood 1, Ghassan Mohammed Abdul Sada 1, Mustafa Hadi Almayali 1

Microbial Bioactives
Views: 466 | Downloads: 0

Clarifies how microalgal diversity underpins scalable bioindustrial performance, guiding evidence-based strain selection, process optimization, and sustainable biotechnology deployment worldwide development.

Abstract | Full Text | Open Access Article

DOI: 10.25163/microbbioacts.9110630
  

Reviews | Antimicrobial Drug Discovery
Published online 22 February 2026 Manuscript-In-Press

Marine Actinobacteria as Emerging Anti-Infective Resources for Acne Vulgaris: A Systematic Review–Driven Perspective on Microbial Dysbiosis, Antimicrobial Resistance, and Novel Therapeutic Opportunities

Amena Khatun Manica 1*, Shahadat Hossain 2

Microbial Bioactives
Views: 201 | Downloads: 0

Marine actinobacteria offer resistance-aware, microbiome-friendly therapeutic pathways to address acne vulgaris amid rising antibiotic failure.

Abstract | Full Text | Open Access Article

DOI: 10.25163/microbbioacts.9110619
  

Reviews | Antimicrobial Drug Discovery
Published online 02 February 2026 Manuscript-In-Press

Biosynthetic Potential of Marine Microbial Communities Revealed Through Metagenomic Insights Into PKS and NRPS Pathways: A Systematic Review and Meta-Analysis

Ahmed Mahmoud Hamood 1*

Microbial Bioactives
Views: 322 | Downloads: 0

Harnessing microbial biosynthetic diversity provides sustainable pathways for discovering novel bioactive compounds with pharmaceutical and industrial applications.

Abstract | Full Text | Open Access Article

DOI: 10.25163/microbbioacts.9110613
  

Reviews | Antimicrobial Drug Discovery
Published online 19 January 2026 Manuscript-In-Press

Reinventing Antibiotic Discovery in the Age of Antimicrobial Resistance: Emerging Sources, Novel Targets, and Post-Genomic Strategies

Gautam Kumar 1, Nileema S. Gore 2, Sankalp Misra 3

Microbial Bioactives
Views: 301 | Downloads: 0

Integrating novel targets, advanced technologies, and underexplored ecosystems is essential to overcome antimicrobial resistance and revive antibiotic discovery.

Abstract | Full Text | Open Access Article

DOI: 10.25163/microbbioacts.9110610
  

Reviews | Antimicrobial Drug Discovery
Published online 14 January 2026 Manuscript-In-Press

From Antioxidants to Enzyme Inhibitors: A Systematic Review and Meta-Analysis of Bioactive Natural Products Targeting Oxidative Stress, Mitochondrial Function, and Microbial Virulence

Feng Zhao 1*, Jiao Bai 2, Changjing Wu 3, Yanru Deng 4, Qingyun Peng 5,6, Weihao Chen 7, Jiao Xiao 2,8

Microbial Bioactives
Views: 328 | Downloads: 0

This review clarifies how structurally diverse natural products selectively target cancer cells and microbial virulence pathways absent in humans.

Abstract | Full Text | Open Access Article

DOI: 10.25163/microbbioacts.9110608
  

Antimicrobial Resistance

Reviews | Antimicrobial Resistance
Published online 07 February 2026 Manuscript-In-Press

Unlocking the Silent Biosynthetic Wealth of Marine Microbiomes: A Systematic Review and Meta-Analysis of NRPS and Polyketide Discovery Strategies

Mitul Bhuptani 1, Vijay Jagdish Upadhye 1, Ramji Gupta 2, Adesh Kolapkar 3

Microbial Bioactives
Views: 300 | Downloads: 0

Marine microbiomes offer a statistically validated and underexplored pathway for accelerating bioactive compound discovery through genome-enabled strategies.

Abstract | Full Text | Open Access Article

DOI: 10.25163/microbbioacts.9110614
  

Reviews | Antimicrobial Resistance
Published online 30 January 2026 Manuscript-In-Press

Marine Bioactive Compounds and Quorum Sensing–Mediated Algae–Bacteria Interactions: Ecological Insights and Biotechnological Opportunities

Tarteel Faisal Ghaze Kanbar 1*

Microbial Bioactives
Views: 380 | Downloads: 0

Marine-derived bioactive compounds offer sustainable, effective alternatives to chemical algicides and antimicrobial agents with minimal ecological impact.

Abstract | Full Text | Open Access Article

DOI: 10.25163/microbbioacts.9110612
  

Reviews | Antimicrobial Resistance
Published online 21 January 2026 Manuscript-In-Press

Hypervirulent Acinetobacter baumannii: A Systematic Review and Meta-Analysis of Virulence Mechanisms and Antimicrobial Resistance

Kai Song 1*, Shuquan Xin 1*, Benkang Xie 1*

Microbial Bioactives
Views: 378 | Downloads: 0

Understanding hvAB mechanisms informs treatment strategies and guides development of targeted interventions against multidrug-resistant, hypervirulent pathogens.

Abstract | Full Text | Open Access Article

DOI: 10.25163/microbbioacts.9110609
  

Reviews | Antimicrobial Resistance
Published online 12 January 2026 Manuscript-In-Press

Unlocking Aromatic Polyketides to Combat Antimicrobial Resistance: A Systematic Review and Meta-Analytic Perspective on Biosynthetic Potential and Synthetic Biology Strategies

Bahareh Nowruzi 1*

Microbial Bioactives
Views: 352 | Downloads: 0

This review highlights aromatic polyketides as scalable, genome-enabled solutions for overcoming antimicrobial resistance and revitalizing antibiotic discovery pipelines.

Abstract | Full Text | Open Access Article

DOI: 10.25163/microbbioacts.9110607
  

Reviews | Antimicrobial Resistance
Published online 08 January 2026 Manuscript-In-Press

Breaking the Biofilm Barrier: Natural Products, Advanced Therapies, and Emerging Strategies Against Streptococcus mutans–Candida Polymicrobial Oral Biofilms

Zubaida Ihsan Thamir 1, Hind Salah Hasan 2*

Microbial Bioactives
Views: 367 | Downloads: 0

Targeting polymicrobial oral biofilms with novel natural and engineered therapies offers sustainable solutions against escalating antimicrobial resistance.

Abstract | Full Text | Open Access Article

DOI: 10.25163/microbbioacts.9110606
  

Aquatic Microbiology

Reviews | Aquatic Microbiology
Published online 21 March 2026 Manuscript-In-Press

Exploring the Frontiers of Cyanobacteria and Microalgae: Integrating Emerging Technologies for Biodiversity Discovery, Metabolic Insights, and Environmental Response

Abu Hena Muhammad Yousuf 1*

Microbial Bioactives
Views: 491 | Downloads: 0

Understanding microalgal metabolite responses aids sustainable biotechnology and environmental adaptation strategies.

Abstract | Full Text | Open Access Article

DOI: 10.25163/microbbioacts.9110631
  

Environmental Microbiology

Reviews | Environmental Microbiology
Published online 24 March 2026 Manuscript-In-Press

Microcystins in Agricultural Systems: Environmental Pathways, Plant Toxicity, and Human Health Risks—A Systematic Review

Md Shafiqur Rahman 1*, Md. Fakruddin 2*

Microbial Bioactives
Views: 119 | Downloads: 0

This study integrates ecological and human health evidence, clarifying how microcystins move through agricultural systems and influence environmental and public health risks.

Abstract | Full Text | Open Access Article

DOI: 10.25163/microbbioacts.9110632
  

Reviews | Environmental Microbiology
Published online 23 January 2026 Manuscript-In-Press

Unlocking the Potential of Fungi and Their Metabolites for Sustainable Agriculture, Nutrition, and Health.

Ronglian Xing 1, Yini Zhang 2, Yu Sun 2*

Microbial Bioactives
Views: 333 | Downloads: 0

Understanding fungal diversity supports sustainable agriculture, human nutrition, and the development of innovative biotechnological applications.

Abstract | Full Text | Open Access Article

DOI: 10.25163/microbbioacts.9110611
  

Microbial Biotechnology

Reviews | Microbial Biotechnology
Published online 18 May 2026 Manuscript-In-Press

Marine Bacterial Carotenoid Pathways as a Reservoir of Functional Xanthophyll Biosynthesis: Enzymes, Diversity, and Engineering Insights

Debananda Singh Ningthoujam 1, Vasudeo P. Zambare 2,3 *

Microbial Bioactives
Views: 108 | Downloads: 0

This study provides quantitative evidence linking enzyme function and marine diversity to enhanced carotenoid yields, guiding targeted metabolic engineering strategies for industry.

Abstract | Full Text | Open Access Article

DOI: 10.25163/microbbioacts.9110636
  

Reviews | Microbial Biotechnology
Published online 20 April 2026 Manuscript-In-Press

Sustainable Biotechnological Approaches for Fungal Laccase Production: Valorization of Agro-Industrial Residues through Solid-State Fermentation

Fardos Marof Bokhari 1*, Magda Mohamed Aly 1, Najwah Yousef Ali Abouznada 1, Samah O Noor 1

Microbial Bioactives
Views: 89 | Downloads: 0

This review demonstrates sustainable enzyme production from agro-industrial waste via solid-state fermentation, advancing circular bioeconomy, waste valorization, and eco-friendly bioremediation technologies.

Abstract | Full Text | Open Access Article

DOI: 10.25163/microbbioacts.9110628
  

Reviews | Microbial Biotechnology
Published online 19 February 2026 Manuscript-In-Press

Advancing Microbial Biofuel Production: Integrating Thermodynamic Principles, Carbon Partitioning, and Microbial Interactions

Anwar Ullah 1*, Shahadat Hossain 2*

Microbial Bioactives
Views: 222 | Downloads: 0

This study, integrating thermodynamic principles, metabolic engineering, and microbial consortia, provides innovative strategies to enhance microbial biofuel productivity and sustainability.

Abstract | Full Text | Open Access Article

DOI: 10.25163/microbbioacts.9110618
  

Reviews | Microbial Biotechnology
Published online 03 January 2026 Manuscript-In-Press

Unlocking Nature’s Pharmacy: A Systematic Review and Meta-Analysis of Bioactive Secondary Metabolites from Microbial, Marine, and Plant Sources

Eyhab R. Al-samawy 1*, Mustafa Salah Hasan 2*

Microbial Bioactives
Views: 331 | Downloads: 0

The systematic exploration of bioactive secondary metabolites (SMs) holds critical significance for medicine, agriculture, and biotechnology. These metabolites represent a treasure trove of structurally diverse molecules with the potential to address urgent global health challenges,

Abstract | Full Text | Open Access Article

DOI: 10.25163/microbbioacts.9110605
  

Microbial Genomics

Reviews | Microbial Genomics
Published online 10 April 2026 Manuscript-In-Press

Illuminating Biological Dark Matter: Integrating Metagenomics, Synthetic Biology, and AI to Unlock Microbial and Genomic Potential for Therapeutics and Biotechnology

Yue Li 1, Shunqi Liu 2 *

Microbial Bioactives
Views: 578 | Downloads: 0

Mapping microbial and human genomic dark matter enables targeted therapeutics and sustainable biotechnological innovations.

Abstract | Full Text | Open Access Article

DOI: 10.25163/microbbioacts.9110627
  

The peer-reviewed and edited version of record published online before inclusion in an issue

|
Published online 29 December 2022

Detection of Legionella pneumophila in the Water Samples of Food Industries and Hospitals in Bangladesh

Nazmun Naher1, Sangita Ahmed1*, and Md. Latiful Bari2

Microbial Bioactives
Views: 1994 | Downloads: 5

PCR-based rapid detection of slow-growing Legionella pneumophila

Abstract | Full Text | PDF (527 KB) Open Access Article

DOI: 10.25163/microbbioacts.525320
  

|
Published online 10 January 2024

Synergistic Efficacy and Mechanism of Probiotics and Prebiotics in Enhancing Health Impact

Sultan Ayesh Mohammed Saghir 1*, Fouad Saleh Al Suede 1

Microbial Bioactives
Views: 2644 | Downloads: 1

Understanding the role of prebiotics and probiotics in health management can enhance immunity, gastrointestinal health, and production efficiency.

Abstract | Full Text | PDF (659 KB) Open Access Article

DOI: 10.25163/microbbioacts.719300
  

|
Published online 17 January 2024

Gut Microbiota's Impact on Neurological Health as The Gut-Brain Axis

Shivani Chib 1*, Loiy Elsir Ahmed Hassan 2, Saikat Mukherjee 3

Microbial Bioactives
Views: 1770 | Downloads: 0

This review discussed the gut-brain connections to suggest therapies for neurological disorders; microbiome modulation shows promise in personalized treatments for diverse ailments.

Abstract | Full Text | PDF (604 KB) Open Access Article

DOI: 10.25163/microbbioacts.719375
  

|
Published online 11 February 2024

Biodegradation as a Sustainable Solution for Environmental Restoration: Bridging the Gap

Mahfoudh A.M. Abdulghani 1*, Fouad Saleh Al-Suede 2, Mohammed Ali Ahmed Saeed 3

Microbial Bioactives
Views: 2179 | Downloads: 1

Bacterial degradation plays a vital role in environmental remediation, breaking down pollutants like hydrocarbons and heavy metals through diverse mechanisms.

Abstract | Full Text | PDF (413 KB) Open Access Article

DOI: 10.25163/microbbioacts.719377
  

These articles have been peer reviewed and accepted for publication. They are still in production and have not been edited, so may differ from the final published form.

|
Published online 29 December 2022


Detection of Legionella pneumophila in the Water Samples of Food Industries and Hospitals in Bangladesh

Nazmun Naher1, Sangita Ahmed1*, and Md. Latiful Bari2

Microbial Bioactives
Views: 1994 | Downloads: 0
DOI: 10.25163/microbbioacts.525320
  

PCR-based rapid detection of slow-growing Legionella pneumophila

Abstract


|
Published online 10 January 2024


Synergistic Efficacy and Mechanism of Probiotics and Prebiotics in Enhancing Health Impact

Sultan Ayesh Mohammed Saghir 1*, Fouad Saleh Al Suede 1

Microbial Bioactives
Views: 2644 | Downloads: 0
DOI: 10.25163/microbbioacts.719300
  

Understanding the role of prebiotics and probiotics in health management can enhance immunity, gastrointestinal health, and production efficiency.

Abstract


|
Published online 17 January 2024


Gut Microbiota's Impact on Neurological Health as The Gut-Brain Axis

Shivani Chib 1*, Loiy Elsir Ahmed Hassan 2, Saikat Mukherjee 3

Microbial Bioactives
Views: 1770 | Downloads: 0
DOI: 10.25163/microbbioacts.719375
  

This review discussed the gut-brain connections to suggest therapies for neurological disorders; microbiome modulation shows promise in personalized treatments for diverse ailments.

Abstract


|
Published online 11 February 2024


Biodegradation as a Sustainable Solution for Environmental Restoration: Bridging the Gap

Mahfoudh A.M. Abdulghani 1*, Fouad Saleh Al-Suede 2, Mohammed Ali Ahmed Saeed 3

Microbial Bioactives
Views: 2179 | Downloads: 0
DOI: 10.25163/microbbioacts.719377
  

Bacterial degradation plays a vital role in environmental remediation, breaking down pollutants like hydrocarbons and heavy metals through diverse mechanisms.

Abstract


The Most Read ranking is based on the number of downloads in the last 60 days from papers published on the Microbial Bioactives within the last 12 months. Usage statistics are updated daily.