EMAN RESEARCH PUBLISHING | Journal of Angiotherapy
Inflammation Cancer Angiogenesis Biology and Therapeutics | Impact 0.1 (CiteScore) | Online ISSN  2207-872X

Journal of Angiotherapy

The Journal of Angiotherapy is an, international, peer-reviewed, Open Access journal that publishes research articles on all aspects of angiogenesis in a continuous publicat More +

Editor-in-Chief:

Journal of Angiotherapy

Volume 8 Number 3 2024

Table of Contents


Published online 03 March 2024

Enhancing Breast Cancer Classification: A Deep Learning Approach with Outlier Detection With Egret Swarm Optimization Algorithm and Feature Selection Integration – A Systematic Review

S. Maria  Sylviaa 1*, N. Sudha 1

pp. 1-8

Early Breast Cancer diagnosis via data mining is crucial. Proposed methods achieve high accuracy, improving treatment outcomes for patients significantly.

Abstract | Full Text | Open Access Article

  

Published online 03 March 2024

Wild Horse Optimizer and Support Vector Machine (SVM) Classifier Predicts The Heart Disease Converging Nature-Motivated Optimization and Machine Learning

Vishwanadham Mandala 1*, Srinivas Naveen Dolu Surabhi 2, V. R. Balaji 3, Dipak Raghunath Patil 4, Saiyed Faiayaz Waris 5, G. Shobana 6

pp. 1-8

Heart disease, responsible for millions of deaths annually, necessitates early detection. Machine Learning offers efficient, cost-effective diagnostic tools. The proposed Wild Horse Optimizer (WHO) and SVM classifier enhance heart disease forecasting, addressing critical healthcare needs.

Abstract | Full Text | Open Access Article

  

Published online 04 March 2024

A Novel Framework of Hybrid Optimization Techniques for Contrast-Enhancement in Cardiac MRI Medical Images

Radhika R. 1*, Rashima Mahajan 1

pp. 1-8

Enhancing medical image contrast improves diagnosis accuracy. COA-SCSO optimizes parameters efficiently, ensuring clearer images and better patient care outcomes.

Abstract | Full Text | Open Access Article

  

Published online 04 March 2024

Integrated Approach for ECG Signal Classification Using Fused Slantlet Transform and Autoregressive Features

 ALI Aalsaud 1*, Raghad Z. Yousif 2, 3

pp. 1-10

The novel ECG analysis method improves detection accuracy, is vital for early diagnosis of CVD, and potentially saves lives, especially in underserved regions.

Abstract | Full Text | Open Access Article

  

Published online 04 March 2024

Modified VGG-19 Deep Learning Strategies for Parkinson's Disease Diagnosis - A Comprehensive Review and Novel Approach

Aruna Kokkula 1*, P. Chandra Sekhar 2, T. M. Praneeth Naidu 3

pp. 1-6

This review describes the upgraded ability to diagnose PD through deep learning and an altered VGG19 model, offering an accuracy rate of nearly 98%, reshaping the neurology treatment field.

Abstract | Full Text | Open Access Article

  

Published online 05 March 2024

Synthesis, characterization and Antibacterial Evaluation of Novel Thiazolidine Derivatives

Shaima H. Abdullah 1*, Mahmoud M. Salih 1, Khalid, A. Al-Badrany 1*

pp. 1-6

Thiazolidine derivatives, synthesized from heterocyclic compounds, exhibit diverse biological activities, including antibacterial effects against various bacterial strains, suggesting potential pharmaceutical applications.

Abstract | Full Text | Open Access Article

  

Published online 05 March 2024

Synthesis, characterization and Antibacterial Evaluation of Novel 1,3-Oxazepine Derivatives Using A Cycloaddition Approach

Farah M. Muhammad 1*, Bushra A. Khairallah 1*, K. A. Albadrany 1*

pp. 1-5

This study demonstrated a novel approach to the synthesis of oxazepine derivatives, key heterocyclic compounds with potential pharmacological applications.

Abstract | Full Text | Open Access Article

  

Published online 06 March 2024

Determination of Health Service for Beneficiary Satisfaction: A Study of Maysan Child and Maternity Hospital

Saad Bader Abbas 1*, Rihab Al-Bedoui Bin Salem 2*

pp. 1-8

Research on health service satisfaction highlights vital insights for improving care, enhancing patient well-being, and optimizing resource utilization for better outcomes.

Abstract | Full Text | Open Access Article

  

Published online 06 March 2024

Prolonged Formalin Exposure on Liver and Kidney Function Associated with TP53 Gene Expression in Quail Birds (Coturnix coturnix)

Iman Ibrahim Al hacham 1, Abdulrazzaq B. kadhim 2*, Eman F. Albaghdady 3

pp. 1-9

This study demonstrated a prolonged formaldehyde exposure in quails. It caused liver and kidney damage and affected gene expression as potential cancer risks.

Abstract | Full Text | Open Access Article

  

Published online 06 March 2024

An intra-oral infection Halitosis and its Causes, Diagnosis, and Treatment Strategies – A Systematic Review

Noora Abdulrazzaq Naji 1*, Safa Ali Hamad 2, Samar Khalid Al-Adel 2, Hamsa Thabet Musa 2, Saja Sami Malik 2 

pp. 1-10

Halitosis, a prevalent issue, often remains untreated, causing social discomfort. Oral causes, especially bacterial buildup, necessitate effective dental management strategies.

Abstract | Full Text | Open Access Article

  

Published online 07 March 2024

Oxidative Stress: Insights into Nutrition, Psychological Stress, Environmental Exposure, and Antioxidants Roles

Iza Safany Che Hanafi 1, Chandrarohini Saravanan 2, Rabiatul Basria S. M. N. Mydin 2*

pp. 1-5

This review discusses how oxidative stress affects our bodies due to factors like diet, stress, and environment, and how antioxidants help. Understanding this is crucial for fighting diseases like cancer and staying healthy.

Abstract | Full Text | Open Access Article

  

Published online 07 March 2024

Healthcare Monitoring-based IoT framework for heart disease detection and classification

J. Shafiq Mansoor 1, Kamalraj Subramaniam 2

pp. 1-11

The review discused the Healthcare Monitoring based IoT framework (HM-IoT) and determined the security rate and classification accuracy.

Abstract | Full Text | PDF (1 MB) | Open Access Article

  

Published online 07 March 2024

Advances in Periodontal Drug Delivery Systems and the Role of Probiotics in Periodontitis Treatment

Pratikshya Mohanty 1, Kalpita Bhatta 1*, Itishree Jogamaya Das 2,  Himansu Bhusan Samal 3*

pp. 1-8

This review discussed the periodontitis and its prevalence in gum inflammation and bone loss. Local drug delivery systems offer effective treatment, enhancing patient care.

Abstract | Full Text | Open Access Article

  

Published online 07 March 2024

Immunological Significance of Meconium-Stained Amniotic Fluid with Complement Factors C3 and CD4 Levels for Pregnancy Health

Hanan Fawzi  Salman 1, Imtithal I. J. 1, Nagam Khudhair 1*

pp. 1-5

This research demonstrated the immune factors C3 and CD4 activity in amniotic fluid on prenatal health, which can diagnose the meconium-stained liquor complications early.

Abstract | Full Text | Open Access Article

  

Published online 07 March 2024

Simulation and Modeling of Water Treatment Plant with GPS-X Software for Health and Water Quality

Nabaa Abdul- Kareem 1*, Jabbar H. Al-Baidhani 1

pp. 1-6

This research determined the quality of the Water Treatment Plant using special software that verified the function of water treatment plants to ensure health safety.

Abstract | Full Text | Open Access Article

  

Published online 08 March 2024

Morphometric Study of Epicardium and Myocardium Thickness in Adult Human Hearts

Noor Abbas Ramadan 1*, Elham Majeed Mahmood 1, Saad Ahmed Mohammed 1

pp. 1-4

This study demonstrated the heart layer morphology, providing insights into cardiac anatomy, age, and gender influences, aiding clinical diagnosis and treatment.

Abstract | Full Text | Open Access Article

  

Published online 08 March 2024

Inflammatory Modulation of Interleukin-17 and -23 in Long COVID Diabetic Patients

Esra Hassan Abd Ali 1*

pp. 1-7

The global COVID-19 pandemic disrupted daily life. This study demonstrated Long COVID's severity, especially in diabetic individuals, highlighting inflammation's crucial role.

Abstract | Full Text | PDF (245 KB) | Open Access Article

  

Published online 08 March 2024

Postmenopausal Hormone, Hematology and Immune Modulation in Rheumatoid Arthritis Patients

Luma Qasim Ali 1, Firas Salih Abdulhadi 1, Ban Talib El-Haboby 1, Jamela Jouda 1*

pp. 1-9

This research determined the significant hematological, hormonal, and immunological changes in postmenopausal women with RA or SLE in compared to controls. This investigation had a high potential for therapeutic intervention.

Abstract | Full Text | PDF (279 KB) | Open Access Article

  

Published online 08 March 2024

Novel Cardiac Biomarkers H-FABP and GPBB for Early Detection and Prognosis of Acute Myocardial Infarction

Hayder T Qaddoori 1*, Fatima Mallalah Mohammed 2, Ali Najm Abdullah 1

pp. 1-12

Novel cardiac biomarkers H-FABP and GPBB might improve the early diagnosis for myocardial infarction detection (within 1-4 hours of chest pain). H-FABP and GPBB proteins were investigated for identifying the heart muscle problems in this study.

Abstract | Full Text | PDF (401 KB) | Open Access Article

  

Published online 08 March 2024

Elytrigia Repens Extracts Control Urban Mosquito Vectors with a Larvicidal Potential

Prakash D 1*, Mohideen Abdulkader M 1, Sakthivel D 1, Manju I 1, Sreenivasan K S 1, Manikandan S 2

pp. 1-6

This study demonstrated larvicidal activity to prevent mosquito disease and its spread, which might be due to insecticidal phytocompounds in the extract.

Abstract | Full Text | Open Access Article

  

Published online 09 March 2024

Risks, Identification, and Antibiotic Susceptibility Against High Prevalence of Bacterial Infection in Contact Lens Solutions

Rana S. Hasan 1,  Sawsan M. Alomari 2, Roaa A. Thamer 3, Mohammed Fadhil Haddad 4*

pp. 1-8

This study determiend the microbial contamination in contact lens solutions for preventing eye infections and improving lens safety practices.

Abstract | Full Text | Open Access Article

  

Published online 09 March 2024

A Rapid Continuous Flow Injection Analysis Method Development for Diphenhydramine Hydrochloride

Asma A. Gayed Al-Ani 1* , Nagham S. Turkey Al-Awadie 1*

pp. 1-8

Novel flow injection analysis improves Diphenhydramine HCL detection in pharmaceuticals with high sensitivity, speed, simplicity, and cost-effectiveness, enhancing industrial efficiency.

Abstract | Full Text | Open Access Article

  

Published online 10 March 2024

Advances in Peer Teaching Methods in the Skill and Physical Development

Sura Gasid Hasan 1*

pp. 1-7

The study showed an innovative education for modern needs, improving basketball skills via peer teaching. Diverse methods motivate learners, enhancing health outcomes.

Abstract | Full Text | Open Access Article

  

Published online 10 March 2024

Heavy Metal Accumulation and Phytochemical Profiling of Brassicaceae and Amaranthaceae for Phytoremediation and Medicinal Applications

Abdulilah Hanan Abdul Qader 1, Hind Hamid Hasan 2, Ashwaq Talib Hameed 3*, Hanan Y. Houmady 4, Rafraf abdul aziz abdul qader 5

pp. 1-7

The study provides valuable insights into heavy metal absorption by specific Iraqi wild plants, offering opportunities for phytoremediation and medicinal applications.

Abstract | Full Text | Open Access Article

  

Published online 10 March 2024

Synthesis, Charecterization, Antibacterial and Cytotoxicity of Novel Metal Complexes Derived from Azomethine Ligand (Bis Azo-Schiff Base) In Vitro and In Silico

Hussein Abdulkadhim Hasan 1*, Saad M. Mahdi 1, Hanaa Addai Ali 2

pp. 1-10

This study demonstrated the synthesis of Schiff bases, like azo-Schiff metal complexes, showing therapeutic effects.

Abstract | Full Text | Open Access Article

  

Published online 11 March 2024

High Fibroblast Growth Factor 23, Sialic Acids, and Albumin Modulation in Alzheimer’s Patients

Hashim Abdul-Sattar J. Al-Bajalani 1*

pp. 1-7

This study demonstrated a potential biomarkers and mechanisms underlying AD pathology for novel therapeutic strategies in future. Understanding serum biomarkers and oxidative stress in Alzheimer's disease (AD) is crucial for early diagnosis and targeted interventions.

Abstract | Full Text | PDF (245 KB) | Open Access Article

  

Published online 11 March 2024

High HbA1C and Glycemic Control as Diabetic Nephropathy Etiology

Iman Kamel Aati 1*, Hawrra Jabbar Mohammed 2, Muhanad Mahdi Mohammed 3, Raya Najim Rasool Altimimy 4

pp. 1-8

High HbA1c levels correlate with diabetic nephropathy severity, urging comprehensive glycemic control for mitigating complications and improving diabetic outcomes.

Abstract | Full Text | Open Access Article

  

Published online 11 March 2024

Control Mycotoxin Contamination in Tarasas Food Using A Lab Fermantion

Baraa Jameel Al-Assil 1,2*, Taghreed Abed Wahwah 3 

pp. 1-7

By utilizing LAB-mediated fermentation, this study demonstrated a natural and effective method for controlling mycotoxin contamination in traditional Tarasas food.

Abstract | Full Text | Open Access Article

  

Published online 12 March 2024

Advances in Diagnosis and Treatment of Fabry Disease: A Review of Clinical Manifestations and Therapeutic Interventions

Mikhail A. Popov 1, Anastasia V. Poznyak 2*, Vladislav V. Dontsov 1, Julia Y. Kotalevskaya 1, Alexey B. Zulkarnaev 1, Vadim S. Tsy-plakov 1, Margarita A. Sazonova 3, Marina D. Sazonova 3, Elizaveta M. Pleshko 4, Victor Y Glanz 4, Vasily N. Sukhorukov 4, and Al-exander N. Orekhov 4*

pp. 1-8

This review discussed a treatment algorithm for advancing medicine, and patient outcomes of Fabry disease.

Abstract | Full Text | Open Access Article

  

Published online 13 March 2024

The Role of Natural Compounds for Atherosclerosis Treatment: Lessons Learned from The Use of Curcumin

Anastasia V. Poznyak 1*, Victoria A. Khotina 2, Roghayyeh Vakili-Ghartavol 3, Victor Y Glanz 2, Vasily N. Sukhorukov 2, and Alexander N. Orekhov 2*

pp. 1-8

Curcumin has various pharmacological effects on atherosclerosis. This review discussed the promising therapeutic potential, of curcumin as anti-inflammatory, lipid regulation, and endothelial function for cardiovascular disease.

Abstract | Full Text | Open Access Article

  

Published online 14 March 2024

Exploring the Link between Chronic Inflammation and Atherosclerosis-Endometriosis Association

Anastasia V. Poznyak 1,*, Vasily N. Sukhorukov 2, Igor A. Sobenin 2, Vladimir P Ofitserov 3, Anton Y. Postnov 2, Alexander N. Orekhov 2,*

pp. 1-8

Understanding shared inflammation mechanisms in atherosclerosis and endometriosis informs innovative interdisciplinary treatments, enhancing patient care and outcomes comprehensively.

Abstract | Full Text | Open Access Article

  

Published online 15 March 2024

Advances in Cellular Models of Atherosclerosis

Anastasia V. Poznyak 1*, Victoria A. Khotina 2, Victor Y Glanz 2, Vasily N. Sukhorukov 1, Igor Alexandrovich Sobenin 2, and Alexander N. Orekhov 1

pp. 1-8

Atherosclerosis models, from 2D cultures to 3D tissue-engineered vessels, offer cost-effective avenues for drug screening and personalized medicine, advancing therapeutic discovery.

Abstract | Full Text | Open Access Article

  

Published online 19 March 2024

A Study of Biochemical Markers in Uterine Cancer Diagnosis with Radiotherpay Treatment In Iraq

Wael Sahib Alnweny 1*, Mohammed Q. Almayali 1*, Mohammed A. Dakhil 2, Hiba Ali Numan 1, Yasir J. Abbas 3

pp. 1-8

Effect and investigation of radiotherapy of clinical biomarkers in Uterine Cancer patients.

Abstract | Full Text | Open Access Article

  

Published online 20 March 2024

Study of Antibiotic Resistance in ESKAPE Bacteria Using β-lactamase and ESBL Genes

Hiba Ahmed Jawade 1*, Zahraa Yosif Motaweq 2, Hawraa Dheyaa Rasool 3,  Fatima Hassan Hussain 1

pp. 1-8

This study determined the resistance mechanisms of SKAPE group bacteria. Understanding this bacterial resistance mechanisms, particularly β-lactamase production, is crucial for effective treatment and infection control.

Abstract | Full Text | Open Access Article

  

Published online 22 March 2024

High Growth Differentiation Factor-15 (GDF-15) in Rheumatoid Arthritis Patients Potential Risk for Cardiovascular Disease

Ghufran Abd Omran Abdulridha 1,2*, Mustafa Abdulkadhim Hussein 3, Suhad Rasheed Majeed 3

 

pp. 1-8

This study showed the high levels GDF-15, a clinical marker in rheumatoid arthritis, signified disease progression and heightened cardiovascular risk, implicating inflammation and tissue damage.

Abstract | Full Text | Open Access Article

  

Published online 23 March 2024

Nanoparticle-Mediated Plasmid Curing in Combating Antibiotic Resistance in Pathogenic Bacteria

Muntaha R. Ibraheem 1*, Dhafar N. Al-Ugaili 2

pp. 1-8

Novel approach fights antibiotic resistance. Enhances DNA extraction efficiency. Eliminates resistance plasmids, aiding biotechnology. Highlights research needs for nanoparticle optimization and mechanism understanding.

Abstract | Full Text | Open Access Article

  

Published online 25 March 2024

Nutritional Evaluation of Cassava Meal Components and Maize in Securing Feed and Food

Shahabuddin Ahmed 1,2, Mrityunjoy Biswas 2*, Atiqur Rahman Sunny 3, Farhana Irin 4, Md Faruk Hossain 5, Md Mostafizur Rahman 5, Md Abu Bakar Siddique 5, Md. Alauddin 6, Mrinal Kanti Debnath 2, Md. Pallo Hossain 2, Tufael 3, 7

pp. 1-8

This study assesses the nutritional composition of cassava and maize, pivotal crops for food and animal feed production globally, offering insights into dietary recommendations, agricultural practices, and food security measures in regions reliant on these staples.

Abstract | Full Text | Open Access Article

  

The peer-reviewed and edited version of record published online before inclusion in an issue

Published online 08 June 2018

Angiogenic Switches Play a Critical Progression in Cancer

Nozlena A Samad a*, Ahmad Bustamam Abdul b, Rasedee Abdullah b, Heshu Rahman b,d,e KZ Khor a, Max Stanley Chartrand  c

The role of angiogenesis in tumor development and operating this very particular switch in controlling tumor.    

Abstract | Full Text | PDF (1 MB) Open Access Article

  

Published online 10 August 2018

Evaluation of antioxidant, antiangiogenic and antitumor properties of Anogeissus leiocarpus against colon cancer

Loiy Elsir Ahmed Hassan a, b*, Foud S. Al-Suade a,  Samah M.Fadul c, Amin Malik Shah Abdul Majid a

Anogeissus leiocarpus is a traditional medicinal plant, used to treat diarrhea, fever, coughs, rheumatism, leprosy, wounds and skin diseases and psoriasis. This study was aimed to investigate the antiangiogenic and cytotoxic effects of six extracts from Anogeissus leiocarpus (leaves and bark).

Abstract | Full Text | PDF (2 MB) Open Access Article

  

Published online 16 August 2018

Targeting inducible Nitric Oxide Synthase (iNOS) in the prevention of vascular damage and cardiac inflammation in CVD

Nafees Uddin Chowdhurya, Abida Tishab, Juthika Sarkerb, Pulak Dev Nathb, Nowshin Ahmedb, Shahanshah Abdullahb, Tasdik Farooqb, Waich Mahmudb, Md. Mohabbulla Mohibb,c, Md. Abu Taher Sagorb

The molecular mechanism of iNOS that leads to CVD is comprehensively summarized in this review so as to aid in drug discovery strategies for the treatment of CVD.

Abstract | Full Text | PDF (3 MB) Open Access Article

  

Published online 07 January 2019

Modes of Anti-angiogenesis in Chemical Perspectives

Shan Arif a, b, Muhammad Imran a, b, Muhammad Adnan Iqbal a, b

In the current study, role of synthesized chemical pharmacores like Humulus lupulus, Hypericum perforatum, Panax ginseng, Coptis chinensis and Rheum palmatum (Varinska et al., 2010) as anti-angiogenesis has been compiled. 

Abstract | Full Text | PDF (3 MB) Open Access Article

  

Published online 04 February 2019

Ethosomal formulation composed of standardized Orthosiphon stamineus extract and sophorolipid inhibits angiogenesis of melanoma in vivo

Mansoureh Nazari Vishkaei a, Mohamed Khadeer Ahamed Basheer c, Amin Malik Shah Abdul Majid a,b

SLOS vesicles can be considered for effective dermal therapeutic agent for the treatment of skin cancer.

Abstract | Full Text | PDF (1 MB) Open Access Article

  

Published online 11 May 2019

Anti-GBM potential of Rosmarinic acid and its synthetic derivatives via targeting IL17A mediated angiogenesis pathway

Md Shamsuddin Sultan Khan A,C,E, Mohammad Adnan Iqbal B, Muhammad Asif A, Tabinda Azam B, Majed Al-Mansoub A, Rosenani S. M. A. Haque B, Mohammed Khadeer Ahamed Basheer C, Aman Shah Abdul Majid D, Amin Malik Shah Abdul Majid A,C,E*

Metal salts and base rosmarinates demonstrated potent anti-GBM efficacy as IL17A inhibitor with minimal toxicity.   

Abstract | Full Text | PDF (1 MB) Open Access Article | Supplementary Material

  

Published online 15 May 2019

Ascorbate blocks acetylcholine- and bradykinin-induced vasodilatation in retinal vascular bed of the bovine isolated perfused eye

Li-xin XU A, Xiao-bo XIA B, Aman Shah Abdul Majid C, Dan Ji B

This study provides insight to EDHF-mediated vasomotor response, as well as various eye disorders caused by dysfunctional retinal arteries, like central retinal artery occlusion.

Abstract | Full Text | PDF (971 KB) Open Access Article

  

Published online 24 June 2019

Evaluation of Safety and Efficacy of Labeesity® for Weight Management and Fatigue in an Obese Female Patient with Hypothyroidism: A Case Report

Aman Shah Abdul MajidA*, Elham FarsiB, Natesan VijayalakshmiC, Syarifah Aisya Syed AmranD, Mahibub Mahadmadsa KanakalE, Zarina Thasneem ZainudeenF*

Labisia pumila extracts based products will require robust studies to be conducted utilizing larger patient numbers and over extended periods of time to rule out any potential toxic effects.

Abstract | Full Text | PDF (769 KB) Open Access Article

  

Published online 03 November 2019

Extract of Urgenia grandiflora inhibited breast cancer cell (MCF-7) proliferation and tumorgenesity

Ibrahim B. E. El Bashir A,B, Loiy Elsir Ahmed HassanC, Amin M. S. Abdul Majid D, Sakina Yagi A*

U. grandiflora could be a new source of chemotherapeutic for breast cancer.

Abstract | Full Text | PDF (3 MB) Open Access Article

  

Published online 30 December 2019

Acute and Sub- chronic Toxicity Study of Encapsulation of Combine Plants Extract of Ficus deltoidea and Gynocthodes sublanceolata in Balb/c Mice Model

Rafida Kh. Ahmed A, M. Syarhabilahmad A, Midhat Nabil A, Fouad Saleih R. Al –Suede B,*

Oral treatment with encapsulated plant extract Ficus deltoidea and Gynocthodes sublanceolata did not appear adverse side effect and it is safe to use for therapeutic purposes.

Abstract | Full Text | PDF (852 KB) Open Access Article

  

Published online 08 July 2020

Phytochemicals in Cancer with Special Emphasis on Ovarian Cancer

Meher U Nessa1,2, Md S Anwar1, Fazlul Huq3*

Reviews current literature on use of phytochemicals in prevention and therapy of ovarian cancer including mechanism of action.

Abstract | Full Text | PDF (1 MB) Open Access Article | Supplementary Material

  

Published online 12 September 2020

Dose Dependent Synergism from Combination of Platinum Drugs with Curcumin against Colorectal Cancer Cell Lines

Hana Bali1, Jun Qing Yu1, Philip Beale2, and Fazlul Huq3

Ox in combination Cur demonstrated very high synergism against HT-29 and Caco-2 cell lines.

Abstract | Full Text | PDF (1002 KB) Open Access Article

  

Published online 13 March 2021

Immunomodulatory and Antiangiogenic Mechanisms of Polymolecular Botanical Drug Extract C5OSEW5050ESA OS Derived from Orthosiphon stamineus

Fouad Saleih R. Al-Suede1*, Mohamed B. Khadeer Ahamed1, Aman S. Abdul MajidSultan Ayesh Mohammed Saghir3, Chern E. Oon4, Amin Malik Shah Abdul Majid1,5*

C5OSEW5050ESA OS strongly curbs variety of angiogenesis modulators in vitro, ex vivo and in vivo.

Abstract | Full Text | PDF (1 MB) Open Access Article

  

Published online 30 October 2021

Cannabis Sativa: A Remedy for Convulsion by Inhibition of GABAA Receptor and Significantly Delayed Onset of Seizure Latency and Death - An Experimental Validation and Molecular Docking

Ben Enoluomen Ehigiator1, SamuelKelechi Mobisson2, Iheanyichukwu Wopara3*, Chinonye Cynthia Chibuife1, Uwaezuoke Chukwuekele Awarajih3, Harrison Ogheneochuko Eruotor3

Abstract | Full Text | PDF (521 KB) Open Access Article

  

Published online 10 November 2021

Immunomodulatory Effect of Tinospora cordifolia with Special Reference to Suppression of Cytokine Storm Induced in SARS-CoV-2

Aishath Thahuseen Waheed1, Thurga Ayavoo2,3, Karthikeyan Murugesan2,3,  Fouad Saleih R. AL-Suede4,5, Ashok Gnanasekaran2,3*

Development of anti-inflammatory herbal drug.

Abstract | Full Text | PDF (464 KB) Open Access Article

  

Published online 11 November 2021

Phytochemicals with Direct and/or Indirect Anti-angiogenic Properties Against Various Cancer Types Focusing on Their Mechanism of Action

Ibrahim Al-deeb1,2,3, Julia Joseph1, Amin Malik Shah Abdul Majid2, Nozlena Abdul Samad1

Abstract | Full Text | PDF (289 KB) Open Access Article

  

Published online 02 February 2022

Evaluation on Antibacterial Activity and Hepatoprotectivity of Rauwolfia serpentina

Gnanasekaran Ashok1,6*, Yukshna A/P Ramunaidu2, Fouad saleih R.AL-Suede3,4 Murugesan Karthikeyan1, Pugazhandhi Bakthavatchalam5, Sajeewa P.  Rathnayake6

The results of this study provide scientific evaluation of antibacterial activity and hepatoprotective effect of Rauwolfia serpentina which will be useful to researchers investigating the compounds with this potential and encouraging the development of new findings in this field.

Abstract | Full Text | PDF (556 KB) Open Access Article

  

Published online 04 March 2022

A Systematic Review on Temporal Lobe Epilepsy Patients with Corona Virus Infection

Pugazhandhi Bakthavatchalam1, Fouad Saleih R.AL-Suede2,3, Sudarshan S.1*

Abstract | Full Text | PDF (197 KB) Open Access Article

  

Published online 04 April 2022

Comparison of anti-inflammatory and analgesic effects of artocarpin-rich Artocarpus heterophyllus extract and artocarpin

Rizwan Rashid Bazmi1, Muhammad Asif2**, Hafiza Sidra Yaseen3, Pharkphoom Panichayupakaranant1,4*

The present study has an impact on overcoming the inflammation problem, which can lead to various types of chronic inflammatory diseases, using the artocarpin  & artocarpin-rich Artocarpus heterophyllus extract. The primary significance of this research is the achievement of preparation of a natural anti-inflammatory and analgesic agent using a green chemistry, which contributes to combat inflammation and analgesia. Furthermore, this method is practically used for industrial commercialization.    

Abstract | Full Text | PDF (909 KB) Open Access Article

  

Published online 20 April 2022

Anti-tumor Activity of NuvastaticTM (C5OSEW5050ESA) of Orthosiphon stamineus and Rosmarinic Acid in An Athymic Nude Mice Model of Breast Cancer

Ashwaq Hamid Salem Yehyaa,*, Majed Ahmed Al-Mansoubb, Fouad Saleih Resq Al-Suedea, Siti Balkees Binti STN Hameed Sultana, Muhammad Asyraf Abduramana, Noor Amanina Azmic, Mufda jameel abedalhadi alrawashdehd, Seyedeh Fatemeh Jafarie, Amin Malik Shah Abdul Majida,f

Abstract | Full Text | PDF (1015 KB) Open Access Article

  

Published online 02 July 2022

Therapeutic Targeting on Death Pathways in Glioblastoma

Pavithra Suppiah1, Julia Joseph1, Rolla Al-Shalabi1, Nik Nur Syazni Nik Mohamed kamal1, Nozlena Abdul Samad1*

Abstract | Full Text | PDF (311 KB) Open Access Article

  

Published online 24 August 2022

Hepatoprotective effect of Hydro-alcohol extract of Mimusops elengi root against antitubercular drug-induced hepatotoxicity in rats

Prakash Dabadi1, Fouad Saleih Resq AL-Suede2,3*, Chandrashekhar VM4*, Mallappa Shalavadi 4 , Ashok Gnanasekaran5

Development of therapeutics for the treatment of hepatotoxicity and oxidative stress  induced by ATDs

Abstract | Full Text | PDF (589 KB) Open Access Article

  

Published online 17 September 2022

Targeting Microtubules by Phytoestrogens for the Treatment of Cancer: An Overview

Fan Xu1, Nozlena Abdul Samad1, Nurhuda Mohamad Ansor1*

In this review, we summarize reported effects of some phytoestrogens that bind directly to tubulin at various binding site and disrupt the microtubule dynamics, either by promoting microtubule polymerization or enhancing microtubule depolymerization.

Abstract | Full Text | PDF (737 KB) Open Access Article

  

Published online 25 September 2022

Environmental and physiological angiogenesis in causing CVD with oxidative pattern

Md. Fakruddin1*, Md. Asaduzzaman Shishir2, Kumkum Rahman Mouree2, Shamsuddin Sultan Khan3

Oxidative stress plays critical role in angiogenesis and cardiovascular disease progression. Drugs targeting oxidative stress might provide a new treatment paradigm for related disorders.

Abstract | Full Text | PDF (1 MB) Open Access Article

  

Published online 04 October 2022

Ferritin and High Sensitivity C-Reactive Protein (hs-CRP) may predict the COVID-19 patient’s fate

Zahra A. Kheudhier1*, Alaa K. Mossa2

Circulating biomarkers are an essential predictor for the prognosis of COVID-19-infected patients as they represent the severity of inflammation and immune status.

Abstract | Full Text | PDF (1 MB) Open Access Article

  

Published online 04 November 2022

Prognostic Factors and Predictors of Mortality in Patients with Critical Limb Ischemia: A Current Clinical Perspective

Moniruddin Chowdhury1,2, Syeda Humayra2, Sohel Mahmud3, Yukihito Higashi4, YD Singh1

PAD and its impact in physical impairment or mortality.

Abstract | Full Text | PDF (201 KB) Open Access Article

  

Published online 15 November 2022

Efficacy of Herbal Medicine as Adjunctive Therapy for Skin Cancer

Norbayu Mansor1, Julia Joseph1, Rola Al Shalabi1, Nozlena Binti Abdul Samad*1

Phytochemicals can be used for skin cancer prevention and treatment.

Abstract | Full Text | PDF (373 KB) Open Access Article

  

Published online 22 November 2022

Immunoglobulin G Seroprevalence of Lassa Fever Virus Among Individuals Residing Along the Banks of River Niger in Anambra State, Nigeria.

Umezurike Kingsley Chimuanya1, Chukwuma Oluchukwu Mariagoretti1,2, Ochiabuto Mary Barbara1, Manafa Patrick Onochie1, Ntum Ifeanyichukwu Michael1, Chukwuma George Okechukwu1,2

LF-specific IgG seroprevalence among inhabitants of river banks in Anambra State, Nigeria

Abstract | Full Text | PDF (292 KB) Open Access Article

  


Published online 24 December 2022

Cancer Immunotherapy in 2022 - End of the Beginning

Assoc. Prof. Dr. Toh Han Chong

Abstract | Full Text

  



Published online 24 December 2022

Precision Medicine in Lymphoid Malignancies

Prof. Dr. Richard Rosenquist Brandell

Abstract | Full Text

  




Published online 24 December 2022

Updates on Treatment of Gastroesophageal Cancers

Prof. Dr. Ho Gwo Fuang

Abstract | Full Text

  

Published online 24 December 2022

Insights into Advanced Non-Small Cell Lung Cancer Patients with MET Alterations

Emeritus Prof. Dr. Liam Chong Kin

Abstract | Full Text

  





Published online 24 December 2022

Targeted Delivery of Cisplatin Using RGD-Modified ZIF-90 as Delivery Vehicle

Emilia Abdulmalek1,2,*, Adamu Abubakar1,3, Kyle. E. Cordova4, Mohd Basyaruddin Abdul Rahman1,2,5

Abstract | Full Text

  


Published online 24 December 2022

Molecular Modelling Analysis of Squamocin as Potential BCL-XL Anti-apoptotic Protein Inhibitor

Kaynat Khimani1, Mohd Faiz Abdul Ghani1,2, Rozana Othman3, Noraziah Nordin1,*

Abstract | Full Text

  

Published online 24 December 2022

Differential Cell Cycle Arrest in Dihydroorotate Dehydrogenase (DHODH) Inhibition of Different Subtypes of Breast Cancer Cell Lines 

Muhammad Aiman Akmal Shahhiran1,2, Mohamad Fairus Abdul Kadir3, Nurshamimi Nor Rashid1,2, Shatrah Othman1,2,* 

Abstract | Full Text

  

Published online 14 May 2023

Investigation Of Anti-Tumour Activity Of Orthosiphon Stamineus On Human Oral Squamous Cell Carcinoma

Shah kamal Bin Jamal Dina, Fouad Saleih Resq Al-Suedeb,c*,Farahnaz Aminid, Aman Shah Abdul Majide, JackTan Chun Keatd, Amin Malik Shah Abdul Majidf .

The potential of Nuvastatic in the treatment of oral squamous cell carcinoma.

Abstract | Full Text | PDF (602 KB) Open Access Article

  

Published online 07 July 2023

Use of Neutralizing Monoclonal Antibodies and Its Outcome Measures in COVID-19 Patients

Moniruddin Chowdhury1,2, Syeda Humayra2, Taha Sulayman3, Keichiro Mihara4, P.K. Rajesh1

The use of monoclonal antibodies in Covid-19.

Abstract | Full Text | PDF (214 KB) Open Access Article

  

Published online 23 July 2023

Diagnostic and differential efficacy of cyclin D1 and CA15-3 in breast cancer and benign breast tumors

Anmar R. Raheem1,2, Omar F. Abdul-Rasheed1*, Omar S. Khattab3, Ahmed Z. Abdulhameed4, Hussein A. Abid1,5*

Abstract | Full Text | PDF (385 KB) Open Access Article

  

Published online 29 July 2023

Design, Synthesis, And Characterization Of New Schiff Bases For 3-Amino-1,2,4-Triazole-5-Thiolate Salt, Bearing Morpholine Ring And Biological Evaluation As Antibacterial Agents

Abeer Hussein Alia, and Mukhlif Mohsin Slaihimb*.

Antibacterial efficacy of new chemical compounds named benzaldehyde derivatives.

Abstract | Full Text | PDF (532 KB) Open Access Article

  

Published online 12 August 2023

A review of the effects of Calophyllum spp. on cancer cells

Melissa Kilus1, Nozlena Abdul Samad1*, Shaari Daud2

Abstract | Full Text | PDF (225 KB) Open Access Article

  

Published online 09 September 2023

Moringa oleifera's Effect on Colorectal Cancer

Rolla Al-Shalabi 1,2, Nozlena abdul samad 1*, Lim Vuanghao 1, Ibrahim Al Deeb 2, Julia Joseph 1

The therapeutic benefit of Moringa plant in cancer treatment

Abstract | Full Text | PDF (2 MB) Open Access Article

  

Published online 03 October 2023

Unlocking Nature’s Treasure Trove: Exploring Microorganisms for Novel Bioactives

Tasbir Amin1, Abu Bakar Karim1, Israk Iram Oyshe1, Amana Hossain1, Tafsir karim1, Jinath Sultana Jime1, Nayeema Bulbul1, Md. Asaduzzaman Shishir2, Ashrafus Safa3, Md. Fakruddin1*

Abstract | Full Text | PDF (299 KB) Open Access Article | Supplementary Material

  

Published online 16 October 2023

Optimizing The Protocol For Extraction Of Bioactive Components From Hibiscus Sabdariffa With Potent Antioxidant Activity

Nur Royhaila Mohamad *1, Farrah Payyadhah Borhan 2, Mohd Shahrizi Razali 3, Roswanira Abdul Wahab 4

Utilize statistical methods to determine which different variables impact the response to the extraction of roselle.

Abstract | Full Text | PDF (514 KB) Open Access Article

  

Published online 21 October 2023

Antioxidant Potential of Calophyllum gracilentum: A Study on Total Phenolic Content, Total Flavonoid Content, and Free Radical Scavenging Activities

Nurr Maria Ulfa Seruji1, Vivien Jong Yi Mian1*, Nor Hisam Zamakshari2, Thiruventhan Karunakaran3, Lee Feng Koo4, Wong Tze Jin4, Chan Thye Huat5

Study of potential Therapeutic activity of Calophyllum herb.

Abstract | Full Text | PDF (444 KB) Open Access Article

  

Published online 22 October 2023

The way of cholesterol in atherogenesis: from the main enemy to complex biomarkers

Anastasia V. Poznyak 1*, Victoria A. Khotina 2, Mikhail A. Popov 3, Alexander D. Zhuravlev 2, Vasily N. Sukhorukov 2, Alexander N. Orekhov 2*

Abstract | Full Text | PDF (998 KB) Open Access Article

  

Published online 02 November 2023

Knowledge and Self-Management Practice Among Diabetic Patients from the Urban Areas in Bangladesh

Md. Jubayer Hossain1, Syeda Tasneem Towhid1,2* , Sumona Akter1 , Muhibullah Shahjahan1, Tilottoma Roy1, Bithi Akter1, Tanjum Ahmed Nodee1

Abstract | Full Text | PDF (481 KB) Open Access Article

  

Published online 11 November 2023

Inhibitory Activity of Enzyme Α-Glucosidase Ethanol Extract Combination Of Mareme Plant (Glochidion arborescens (Müll. Arg.) Boerl.) Leaves And  Sala Plant (Cynometra ramiflora Linn) Leaves

Haryoto1*, Alysa Vivi Arnida1, Peni Indrayudha1, Cita Hanif Muflihah1, Khong Heng Yen2

Mareme and Sala leaves mix may be a strong blood sugar blocker, but it contains useful chemicals for potential medical research.

Abstract | Full Text | PDF (318 KB) Open Access Article

  

Published online 12 November 2023

Stromal Interaction Molecule-1 (STIM1): Orchestrating Calcium Signaling in Cancer and Hematologic Malignancies

Rabiatul Basria S. M. N. Mydin1, Adam Azlan1, Eman Salem Saeed Algariri,1 Nur Azuar Abdul Rahim2,3, Emmanuel Jairaj Moses1, Narazah Mohd Yusoff1

Abstract | PDF - $50.00 (199 KB) Buy Now

  

Published online 14 November 2023

Antiangiogenic and Anticancer Potential of Supercritical Fluid Extracts from Nutmeg Seeds; In vitro, Ex vivo and In silico studies

Sawsan S. Al-Rawi1*, Ahmad Hamdy Ibrahim2, Marthad A. Hamde3, Dinesh Babu4, Mansoureh Nazari5, Mohd Omar Ab Kadir6, Aman Shah Abdul Majid7, Amin Malik Shah8

Abstract | Full Text | PDF (2 MB) Open Access Article

  

Published online 23 November 2023

Comparative Analysis of Epstein-Barr Virus EBNA-2 Sequence Variation in Nasopharyngeal Carcinoma and Other EBV-Related Tumors

Lee Wei Zheng1,2, Rabiatul Basria S. M. N. Mydin1*, Adam Azlan1,5 and Muhamad Yusri Musa3,4

Abstract | Full Text | PDF (389 KB) Open Access Article

  

Published online 24 November 2023

Hepatitis C and Atherosclerosis: Inflammatory Interplay

Anastasia V. Poznyak 1*, Ludmila V Nedosugova 2, Vasily N. Sukhorukov 3, Alexandra A. Melnichenko 3, Elizaveta M. Pleshko 3 and Alexander N. Orekhov 3

A review of the relationship between HCV infection, inflammation, and cardiovascular pathologies.

Abstract | Full Text | PDF (709 KB) Open Access Article

  

Published online 24 November 2023

Effect of Plumbago zeylanica on Analgesia and Arthritis

Subasini Uthirapathy1*

The inhibition activity of PZ on carrageenan-induced arthritis, humoral and cellular immunity, and pain and inflammation.

Abstract | Full Text | PDF (225 KB) Open Access Article

  

Published online 27 November 2023

Pomegranate Juice Attenuates Anti-ulcer in Indomethacin-induced Peptic Ulcer

Ali Omar Yaseen 1, Payam Jamal Muhamed 1, Hacer Haltas 1 , Subasini Uthirapathy 1*

Study on using pomegranate juice supplements to treat ulcers caused by pain medications.

Abstract | Full Text | PDF (489 KB) Open Access Article

  

Published online 27 November 2023

Characterization of Essential Oil Composition of Syzygium aromaticum Linn. (Clove) by GC-MS and Evaluation of its Antioxidant Activity

Javed Ahamad 1*

The study of Clove essential oil as an antioxidant drug.

Abstract | Full Text | PDF (472 KB) Open Access Article

  

Published online 05 December 2023

Gymnemagenin a Promising Drug Candidate for Management of Hyperglycemia: In-Vitro and In-Vivo Study

Javed Ahamad1, Saima Amin2, Kamran J Naquvi1, Showkat R Mir3*

Study of Gymnema sylvestre plant for the treatment and management of diabetes.

Abstract | Full Text | PDF (1 MB) Open Access Article

  

Published online 08 December 2023

Current Perspective on Pesticides: Their Classification, Behaviour, Potential Use and Toxic Effects

Adil Ahamad1*, Javed Ahamad2, Mohd. Javed Naim2

Monitoring the use of pesticide and analyzing their acceptable levels for human health.

Abstract | Full Text | PDF (442 KB) Open Access Article

  

Published online 04 December 2023

Drug Repositioning and Response Detection Based on Randomized Control Trials for Cancer Treatment - A Review

Aman Chandrakar 1, Chetan Kumar Sonkar 2

The cancer treatment will be accelerated through drug repositioning.

Abstract | Full Text | PDF (1 MB) Open Access Article

  

Published online 01 January 2024

Black Soldier Fly Larvae Feed with Fermented Bamboo Culms Enriched with Lactic Acid Bacteria

Nurul Azila Abdul Razak 1, Ang Chung Huap 1*, Vivien Jong Yi Mian 1, Siti Nor Ain Seri Masran 2

The study of plant-based protein source as  the nutrition of Black soldier fly

Abstract | Full Text | PDF (758 KB) Open Access Article

  

Published online 05 December 2023

A Review of Potential Roles for Micro RNAs as Drugs Sensitivity Biomarkers in Breast Cancer

Monika Barsagade 1*, Ravi kishore Agrawal 2*

The role of miR-202's in discovering biomarkers for early diagnosis and improving therapeutic strategies for breast cancer.

Abstract | Full Text | PDF (393 KB) Open Access Article

  

Published online 06 December 2023

Evaluation of Cardiac Reserve Using Echocardiography for The Detection of Mild Cardiac Dysfunction in Mice - A Review

Sanjay Kumar Mire 1, Deepak Kumar Sahu 2

Echocardiography-based strain imaging offers early detection of cardiac abnormalities, treatment, and research strategy. 

Abstract | Full Text | PDF (951 KB) Open Access Article

  

Published online 06 January 2024

Determination of Active Biomarkers and the Antioxidant and Antibacterial Potential of Standardized Zygophyllum spp Extract

Mostafa Alamholo 1

Identification of active compounds in medicinal plants to control resistant bacteria

Abstract | Full Text | PDF (434 KB) Open Access Article

  

Published online 07 January 2024

Evolution of Genes and Transcripts Modifies Drug Sensitivity in Cancer Cell Lines - A Review

Krishna Sahu 1, Urvashi Jain 2

Dynamic genomic and transcriptomic evolutionary modeling guides cancer genetics, transforming treatment by predicting drug sensitivity in genomics.

Abstract | Full Text | PDF (196 KB) Open Access Article

  

Published online 07 December 2023

Discovering Novel and Old Drug Targets in Oral Cancer Stem Cells Using bio-inspired methods - A Review

Vijay Kumar Jaiswal 1, Mahendra Kumar Verma 2

Evolutionary Computation Network for Drug Repositioning reveals oral cancer stem cells, informing targeted therapies for treatment.

Abstract | Full Text | PDF (1 MB) Open Access Article

  

Published online 07 December 2023

Impedimetric Sensor Aided by Polydopamine Nanoparticles for Label-Free Detection of Breast Cancer Cells - A Review

Bhuneshwari Dewangan 1, Naina Bhoyar 2

 

A review of polydopamine sensor in breast cancer diagnosis.

Abstract | Full Text | PDF (882 KB) Open Access Article

  

Published online 08 December 2023

Analyzing The Risks, Benefits, and Therapeutic Potential of Cannabis And Cannabinoids in Tumor Therapy - A Review

Poorti Sharma 1*, Lukeshwari Sahu 1

Study explores Cannabis use by metastatic tumor patients, analyzing active components, addressing gaps in research, and promoting informed medical guidance.

Abstract | Full Text | PDF (769 KB) Open Access Article

  

Published online 08 December 2023

Review on Health And Quality of Life of Elderly People: A Meta-Analysis from The Medical and Health Sciences

Ashish Agarwal 1*, Sachin Pradhan 2

An IoT-based system enhancing elderly care, emphasizing QOL, independence, and support, aiding healthcare development for seniors' well-being.

Abstract | Full Text | PDF (670 KB) Open Access Article

  

Published online 08 December 2023

The Clinical, Histological, and Immunohistochemical Features of Bone Metastases - A Review

Ragini Patel 1*, Yogendra Sahu 2

A deep learning model to trace bone metastasis origins, addressing challenges in diagnosis and emphasizing therapeutic implications and monitoring.

Abstract | Full Text | PDF (698 KB) Open Access Article

  

Published online 12 December 2023

Hydrophobin-Coated Noisomes as Drug Carriers in Lung Cancer Cells - A Review

Srishti Namdeo 1, Chandrapratap Dhimar 2

Targeted nanoparticle delivery to Lung Cancer Cells, using hydrophobin-coated niosomes, addressing multidrug resistance, and enhancing treatment efficacy.

Abstract | Full Text | PDF (880 KB) Open Access Article

  

Published online 14 December 2023

Predictive Modeling of The Chronic Pain-Induced Depression in Old Adults Based on Music Intervention

Birendra Kumar Sahu 1, Chiranjeev Singh 2

This research addresses the prevalent issue of chronic pain in older adults, proposing a novel Predicting Chronic Pain-based Music Intervention model for personalized, effective treatment, showcasing promising results for mental well-being improvement.

Abstract | Full Text | PDF (1 MB) Open Access Article

  

Published online 14 December 2023

Analysis of Semi-Rural and Urban Hypertension Prevalence Using WHO Measures

Sumit Kumar Agrawal 1, Tripti Dewangan 2

Guiding a tailored intervention and strategy to advance global hypertension management

Abstract | Full Text | PDF (1 MB) Open Access Article

  

Published online 17 December 2023

Menopause-Related Insomnia, Cognitive, Behavioral, and Mindfulness-Based Treatments

Venu Anand Das 1, Jitendra Sinha 2

The study explores challenges in treating menopausal symptoms, introducing the Menopause-based Treatment Study Framework (MTSF) for more effective and enduring resolution.

Abstract | Full Text | PDF (1 MB) Open Access Article

  

Published online 17 December 2023

Epidermal Growth Factor Receptor and Double-Imprinted Nanoparticles for Targeted Cancer Drug Delivery - A Review

Lakhan Lal Kashyap 1, Harish Jaiswal 2

A targeted drug delivery approach, using double-imprinted nanoparticles and EGFR-SVM, to enhance anticancer drug effectiveness selectively in tumor cells.

Abstract | Full Text | PDF (446 KB) Open Access Article

  

Published online 19 December 2023

Identifying Thyroid Dysfunction Using Standard Laboratory Testings – A Systematic Review

Vinay Jaiswal 1, Prachi Gurudiwan 2

A ML-TDI model for thyroid dysfunction identification, addressing underdiagnosis challenges and emphasizing the importance of comprehensive assessment in care.

Abstract | Full Text | PDF (616 KB) Open Access Article

  

Published online 21 December 2023

Screening for Oral Cancer Using Brush Biopsies and DNA Image Cytometry - A Review

Pranjali Verma 1,  Shikha Kumari Rajak 2

A non-invasive DNAIC-DCNN for accurate oral cancer diagnosis, offering targeted medications for effective treatment.

Abstract | Full Text | PDF (401 KB) Open Access Article

  

Published online 21 December 2023

The Effect of Naturally Occurring Dietary Chemicals and Food-Borne Mycotoxins on DNA Methylation and Cancer - A Review

Moniza Nurez Khan 1, Naresh Chandravanshi 2

The critical impact of Food-Borne Mycotoxins (FBM) and Artificial Light At Night (ALAN) on DNA methylation, influencing cancer risk and disease outcomes.

Abstract | Full Text | PDF (325 KB) Open Access Article

  

Published online 22 December 2023

Analyzing the Influence of Initial Diagnosis on Interpersonal Problem Trajectories in Residential Treatment for Eating Disorders - A Review

Hemlata Dewangan 1, Neetish  Kumar 2

A systematic review of post-residential treatment outcome for eating disorders

Abstract | Full Text | PDF (662 KB) Open Access Article

  

Published online 25 December 2023

Physical Activity Correlates With The Aging Process in Seniors Broadly - A Review

Bhuneshwari Dewangan 1, Naina Bhoyar 2

A review of a correlation between physical activity, life satisfaction, and aging in the senior age group with Internet of Things (IoT) based Physical Activities (IoT-PA) model

Abstract | Full Text | PDF (406 KB) Open Access Article

  

Published online 29 December 2023

Brain-Computer Interfaces Can Significantly Improve The Quality of Life for Aged People - A Review

Sanjay Kumar Mire 1, Deepak Kumar Sahu 2

A non-invasive Brain-Computer Interfaces (BCIs) and IoT-based Smart Home Technology can enhance memory, focus, and aged people's quality of life.

Abstract | Full Text | PDF (625 KB) Open Access Article

  

Published online 08 January 2024

Gut-Brain Connection; IBS linked to Anxiety, Quality of Life, and Academic Performance in Undergraduate Students

Mohamed Sadeq Al-Ibrahim *1, Ahmad Hamdy Ibrahim 2, Sawsan S. Al- Rawi *3, Bayram Dawod Ahmed 4, Nalan Linda Fraim 5

Chronic stress affects many physiological processes including immunity and angiogenesis. IBS impacts anxiety, quality of life, and academic performance of undergraduate students.  

Abstract | Full Text | PDF (305 KB) Open Access Article

  

Published online 08 January 2024

A Review of Dipeptidyl Peptidase-4 (DPP-4) and its potential synthetic derivatives in the management of Diabetes Mellitus

Mohd. Javed Naim 1

To establish potential DPP-4 inhibitors. 

Abstract | Full Text | PDF (808 KB) Open Access Article

  

Published online 11 January 2024

Polycystic Ovarian Syndrome: An Overview with Special Consideration to Its Oral and Pediatric Clinical Manifestations

Zeba Saleem 1, Abiha Ahmad Khan *1, Syeda Aamena Naaz 1 and Mohd. Javed Naim 2

Highlighting the oral and pediatric manifestation of PCOS. 

Abstract | Full Text | PDF (1 MB) Open Access Article

  

Published online 12 January 2024

An In-Depth Analysis of Microorganisms Linked to Various Forms of Hospital-Acquired Infections: A Systematic Review

Nadirah Yusof 1,  Rabiatul Basria S. M. N. Mydin 1,2*, Chandrarohini Saravanan 2,3,4, Nor Hazliana Harun 2,5, Siti Salmah Noordin 5

The study aims to provide a detailed understanding of the microorganisms involved in different types of HAIs, such as surgical site infections, urinary tract infections, bloodstream infections, and respiratory tract infections.

Abstract | Full Text | PDF (247 KB) Open Access Article | Supplementary Material

  

Published online 12 January 2024

Platelet Implication in Atherosclerosis Pathogenesis

Anastasia V. Poznyak 1*, Varvara A. Orekhova 1, Vasily N. Sukhorukov 1, Alexandra A. Melnichenko 2, Elizaveta M. Pleshko 2, Alexander N. Orekhov 1

Platelets' vital role in health, thrombosis, atherosclerosis; therapy's ongoing clarification.

Abstract | Full Text | PDF (541 KB) Open Access Article

  

Published online 15 January 2024

Maternal Hypercholesterolemia is a Significant Risk Factor for Atherogenesis – A Systematic Review

Anastasia V. Poznyak 1*, Victoria A. Khotina 2, Vasily N. Sukhorukov 2, Nikolay Sadykhov 2, Anton Y Postnov 2, and Alexander N. Orekhov 2*

Maternal hypercholesterolemia during pregnancy influences fetal development, leading to lasting atherosclerotic changes, emphasizing preventive strategies to reduce future cardiovascular disease burdens.

Abstract | Full Text | PDF (935 KB) Open Access Article

  

Published online 16 January 2024

An Educational Intervention to Improve Adverse Drug Reactions Reporting Among Healthcare Practitioners in Selected Pediatric Hospitals in Iraq

Bootan A. Salih 1,*, Omer Q. Allela 2, Raad A Kaskoos 3, Javed Ahamad 4

The main goal of the study is to design an intervention program to increase knowledge attitude and practice of healthcare practitioners towards pharmacovigilance.

Abstract | Full Text | PDF (738 KB) Open Access Article

  

Published online 17 January 2024

Innovative Piperidine-Catalyzation in Protecting Carbonyl Compounds with Implications for Angiogenesis and Inflammation

Mukhlif Mohsin Slaihim 1*, Luay Ali Dhahi 1, Abeer Hussein Ali 1

Introduced piperidine-catalyzed protection in aldehydes, guiding anti-cancer compound optimization.

Abstract | Full Text | PDF (804 KB) Open Access Article | Supplementary Material

  

Published online 18 January 2024

Effect of Toll-Like Receptor 9 (TLR9) in Breast Cancer Risk, Along with Hormonal Effects in Patients Receiving Radiotherapy

Asra'a Adnan Abdul-Jalil 1, Marrib N. Rasheed 2, Rana H. Hamoode 3

TLR9 rs187084 polymorphisms crucial in Iraqi women's breast cancer susceptibility.

Abstract | Full Text | PDF (281 KB) Open Access Article

  

Published online 19 January 2024

Optimizing Fast-Dissolving Tablets of Ketotifen: Impact of Sodium Bicarbonate and Citric Acid in Formulation and Evaluation

Rozhan Arif 1, Sharad Visht 1*, Ali Omar Yassen 1, Sana Sirwan Salih 1

Formulating ketotifen fast-dissolving tablets (FDT) tackled poor bioavailability challenges, emphasizing sodium bicarbonate's pivotal role for rapid tablet disintegration, highlighting FDT viability for asthmatic treatment.

Abstract | Full Text | PDF (556 KB) Open Access Article

  

Published online 20 January 2024

Significance of Serum Biomarkers in Early Diagnosis of Hepatocellular Carcinoma in Patients with Fisher Groups

Tufael 1, Auditi Kar 2, Vijay Jagdish Upadhye 3*, Amith Dutta 4, Md Royhanur Islam 5, Abdus Sattar 6, Md. Eunus Ali 7, Julakha Akter 8, Kaniz Fatima Bari 9, Md. Tahsin Salam 10, Palash Chandra Banik 11, Md Shamsuddin Sultan Khan 12, Atiqur Rahman Sunny 6*

The research addresses a crucial gap by linking the unique lifestyle and stressors in fisher groups to hepatocellular carcinoma.

Abstract | Full Text | PDF (410 KB) Open Access Article

  

Published online 20 January 2024

Advancing Therapeutic Efficacy of Star Anise Oil with (Illicium verum) Nano-Emulsion Formulation

Sharad Visht 1, Sana Sirwan Salih 1, Belan Azad Ibrahim 1, Daniah Issa Ismael 1, Serwa Falah Abdalwaheed 1, Omji Porwal 1

Star anise oil-based nano-emulsions' extraction, purification, and formulation processes to improve therapeutic efficacy of drug substances

Abstract | Full Text | PDF (1 MB) Open Access Article

  

Published online 20 January 2024

A Review of Healing Potential of Indian Flora: An Ethnopharmacological Evidence of Wound Healing Activity

Rasmita Jena 1,2, Durga Madhab Kar 1*, Sovan Pattanaik 1, Bhisma Narayan Ratha 3

This review emphasizes the rich potential in traditional practices, offering valuable insights and solutions to current healing challenges.

Abstract | Full Text | PDF (934 KB) Open Access Article

  

Published online 21 January 2024

Renal and Hepatic Toxicity of Alpha-Cypermethrine Pesticide Used on Agricultural  Farmers Living Closed to Tigris river, Iraq

Sarhan Rashid Sarhan 1*,   Mohammed H.M. Merah 2

ALP, ALT and AST enzymes increased significantly when directly exposed to this pesticide as a result of its effect on kidney and liver functions.

Abstract | Full Text | PDF (436 KB) Open Access Article

  

Published online 21 January 2024

Therapeutic Effects of Esomeprazole, Curcumin, Chitosan, and Curcumin-Chitosan Mixture on Ethanol-Induced Gastric Ulcer in Female Rats

Jenan Mahdi Jawad Al-kawaz 1*, Fakhir Magtoof Al-Zubaidy 2**, Hussein Jassim Obaid Al -Harbi 1***

Evaluate the healing effects of esomeprazole, curcumin, chitosan, and a curcumin-chitosan mixture on gastric injuries induced by ethanol in rats.

Abstract | Full Text | PDF (737 KB) Open Access Article

  

Published online 21 January 2024

Synthesis And In-Silico Anti-Cancer Potential of N-Aryl-Keto-Nitrone As A Spin Adducts

Rita S. Adam 1*

Advancing spin trapping chemistry through the introduction of effective linear keto-nitrones, expanding applications and refining practical use.

Abstract | Full Text | PDF (463 KB) Open Access Article

  

Published online 22 January 2024

Effect of Metformin and Vitamin D Supplementation on Metabolic and Hormonal Profiles in Polycystic Ovary Syndrome Women: A Follow-Up Study

Zainab Nur-Eldeen Aziz 1*, Basil O. Saleh 1

Positive Impacts of Metformin and Vitamin D Supplementation on Polycystic ovary syndrome (PCOS) Women

Abstract | Full Text | PDF (232 KB) Open Access Article

  

Published online 22 January 2024

Anti-Cancer Study of Carvacrol in Hypoxic-Induced Colorectal Cancer Cell

Aumaima Tariq Abed 1,2* ,  Ahmed MH AlMudhafar 1 , and Najah R Hadi 1

Effect of carvacrol on proliferation and migration of hypoxic SW480 cancer cells

Abstract | Full Text | PDF (586 KB) Open Access Article

  

Published online 22 January 2024

Effect of Steroid Treatment on Tissue Damage Markers in Diabetic Patients

Mohammed Shakir Ali 1*, Ali Al-Shammari 1, Qutaiba A. Ismael 1, Obaida Amer Imran 1, Mohammed H. Al-Bayati 1

This research showed how diabetes and steroids worsen effects, providing a better understanding of the pathophysiology processes.

Abstract | Full Text | PDF (381 KB) Open Access Article

  

Published online 22 January 2024

Synthesis, Characterization and In Vitro Anti-cancer  Properties of Cationic Gemini Surfactants with Alkyl Chains in Human Breast Cancer

Anwar Shalan F. 1*, Samah Hussein Kadhim 1

Anti-cancer activity of Gemini surfactants in human breast cancer cells

Abstract | Full Text | PDF (1 MB) Open Access Article

  

Published online 22 January 2024

Impact of Various Contraceptive Methods on Immunological Profiles in Women: A Serological Analysis in Diyala Governorate

Shaymaa Mohammed Alwan 1, Maha Falih Nazzal 2, Inaam Faisal Mohammed 3

Abstract | Full Text | PDF (272 KB) Open Access Article

  

Published online 22 January 2024

Two Forms of C-Reactive Protein and Their Implication for Atherogenesis: Focus on Monomeric Form

Anastasia V. Poznyak 1*, Victoria A. Khotina 2, Anton Y Postnov 2, Vasily N. Sukhorukov 2, Nikolay Sadykhov 2, Alexander N. Orekhov 2*

A review on inflammatory protein in atherosclerosis progression.

Abstract | Full Text | PDF (1 MB) Open Access Article

  

Published online 22 January 2024

Machine Learning-Based Enhanced Drug Delivery System and Its Applications – A Systematic Review

Abhijeet  Madhukar Haval 1*, Kumar Shwetabh 1, Sushree Sasmita Dash 1

Machine Learning (ML) transforms drug development, predicting drug properties, targets, interactions, and facilitating efficient exploration for researchers and pharmaceutical companies.

Abstract | Full Text | PDF (528 KB) Open Access Article

  

Published online 23 January 2024

A Systematic Review of Advanced Approaches in Wound Healing: Simvastatin Polymeric Nanoparticles and Postbiotics Innovation

Chandrapratap Dhimar 1*, Krishna Sahu 1, Moniza Nurez Khan 1

Utilizing innovative postbiotics and Simvastatin Polymeric Nanoparticles, wound research accelerates healing, promising improved treatment with minimal inflammation.

Abstract | Full Text | PDF (682 KB) Open Access Article

  

Published online 23 January 2024

A Review of Modeling Checkpoint Blockade Therapy and Therapeutic Strategies in Integrative Pharmacological Approach for Metastatic Breast Cancer

Prachi Gurudiwan 1*, Ragini Patel 1, Urvashi Jain 1

Quantitative Systems Pharmacology models immune processes in breast cancer, aiding personalized treatment by identifying biomarkers, resistance mechanisms, and therapeutic options

Abstract | Full Text | PDF (1 MB) Open Access Article

  

Published online 23 January 2024

In vitro Antibacterial Activity of Seribu kuman Leaf (Rhinacanthus nasutus (l.) Kurz) Extracts Against Staphylococcus aureus and Pseudomonas aeruginosa

Betty Fitriyasti 1*, Siska Ferilda 2, Widia Sari 3, Muhammad Rizki Saputra 4, Heng Yen Khong 5*

Rhinacanthus nasutus extract inhibits the growth of Staphylococcus aureus and could serve as an alternative in treating infections caused by S. aureus.

 

Abstract | Full Text | PDF (396 KB) Open Access Article

  

Published online 24 January 2024

The Characterization of Acute Myeloblastic Leukemia-M2 Cell Lines with Suppressed Stromal Interaction Molecule 1 (STIM1) and its Impact on Calcium/Reactive Oxygen Species Profiles

Eman Salem Algariri 1,2, Rabiatul Basria S. M. N. Mydin 1*, Emmanuel Jairaj Moses 1, Nur Arzuar Abdul Rahim 3, Narazah Mohd Yusoff 3

STIM1's potential role in promoting AML-M2 cell survival by regulating calcium/ROS interactions, as well as KRAS/MAPK and Akt-related pathways

Abstract | Full Text | PDF (604 KB) Open Access Article

  

Published online 24 January 2024

A Comprehensive Review on Cardiovascular Disease Detection, Risk Assessment, And Treatment Using A Network Pharmacology Model

Vijay Kumar Jaiswal 1*, Monika Barsagade 1, Jitendra Sinha 1

Contribution to advancing diagnostic methods, proposing innovative treatment approaches, and demonstrating the effectiveness of pharmacist-led preventive strategies for improving population health, reducing the economic burden of cardiovascular diseases, and showing more personalized and mechanism-based approaches in healthcare.

Abstract | Full Text | PDF (834 KB) Open Access Article

  

Published online 24 January 2024

Advancements in Ocular Vascularization Analysis Using Deep Learning Techniques – A Systematic Review

F Rahman 1*, Akanksha Mishra 1, Sushree Sasmita Dash 1

This review shows an advanced machine learning method for efficient segmentation and classification of blood vessels in medical images, revolutionizing diagnostic precision.

Abstract | Full Text | PDF (975 KB) Open Access Article

  

Published online 25 January 2024

Advances of AI-driven Drug Design and Discovery in Pharmaceuticals - Review

Dev Ras Pandey 1*, Sushree Sasmita Dash 1, Akanksha Mishra 1

The application of AI in pharmaceuticals holds the promise of personalized therapies, streamlined production, and improved market strategies, making it an indispensable tool for the future of drug development.

Abstract | Full Text | PDF (1 MB) Open Access Article

  

Published online 25 January 2024

Smart Wound Monitoring and Healing Assessment System With Deep Learning Methods - A Systematic Review

Abhijeet  Madhukar Haval 1*, Akanksha Mishra 1, Sushree Sasmita Dash 1

Wound features impact healing; indicators like temperature, oxygen levels, and moisture influence the process. This review shows and effective at-home wound monitoring with biosensors.

Abstract | Full Text | PDF (962 KB) Open Access Article

  

Published online 26 January 2024

Advances in Image Processing Methods for Breast Cancer Diagnosis and Classification Using A Hybrid Machine Learning – A Systematic Review

Priya Vij 1, Sushree Sasmita Dash 1, Akanksha Mishra 1

Advanced integration of deep learning (AlexNet) and SVM-RBF for breast cancer diagnosis surpasses existing models, ensuring precise and reliable early detection.

Abstract | Full Text | PDF (899 KB) Open Access Article

  

Published online 26 January 2024

A Pharmacy System Integrated with A Machine Learning Algorithm for Cardiovascular Disease Prediction

Kumar Shwetabh 1*, F Rahman 1, Sushree Sasmita Dash 1

The review explores an inclusive ML structure, vital for efficient CVD forecasting. The proposed model showcases superior accuracy, emphasizing the need for comprehensive predictive algorithms in cardiovascular health research.

Abstract | Full Text | PDF (1 MB) Open Access Article

  

Published online 05 February 2024

Vitamin D Deficiency As A Contributor To Atherosclerosis Development – A Review

Anastasia V. Poznyak 1*, Victoria A. Khotina 2, Alexandra A. Melnichenko 2, Victor Y Glanz 2, Vasily N. Sukhorukov 2, and Alexander N. Orekhov 2*

Vitamin D deficiency and cardiovascular diseases, explores role in inflammation, oxidative stress, and vascular calcification

Abstract | Full Text | PDF (900 KB) Open Access Article

  

Published online 08 February 2024

Repurposing Drugs for Overcoming Therapy Resistance in Colon Cancer – A Review

Mahdi Darvishi 1, Amir Mohammad Chekeni 2, Mohammad Fazelhosseini 1, Zeenat Iqbal 3*, Mohd Aamir Mirza 3*, Mohammed Aslam 4, Esra Tariq Anwer Bayrakdar 4

Oncology research seeks new therapies for aggressive CRC, utilizing repurposed drugs for accelerated and safer treatment approaches.

Abstract | Full Text | PDF (841 KB) Open Access Article

  

Published online 09 February 2024

A Review of 3d Printing Model of New Blood Vessel Formation For Pharmaceutical Applications

Nidhi Mishra 1*, Priya Vij 1, Akanksha Mishra 1

Innovative synthetic blood vessels offer promising solutions for cardiovascular diseases, providing safer, more accessible treatments for aging populations

Abstract | Full Text | PDF (530 KB) Open Access Article

  

Published online 09 February 2024

Efficient Removal of Acetamiprid Pesticide Using Date Core-Derived Activated Carbon and Korai Clay As A Good Sorbent

Huda Azhar Fadel 1*,  Lekaa Hussein Khdaim 1

Iraqi date core-derived activated carbon effectively removes acetamiprid pesticide, crucial for combating water pollution, supported by comprehensive adsorption studies.

Abstract | Full Text | PDF (550 KB) Open Access Article

  

Published online 12 February 2024

A Double-blind, Randomized Clinical Trial Study of Plantago major l. Syrup on Menorrhagia

Sajedeh Ghasempour 1, Mohsen Naseri 2, Fatemeh Alijaniha 2, Yasin Karimi 3, Anoushirvan Kazemnejad 4, Shahrzad Hadavand 5 , Seyedeh Fatemeh Jafari 2, 6

The study highlights Plantago major's potential to reduce menorrhagia severity and duration, offering a promising complementary treatment with minimal side effects.

Abstract | Full Text | PDF (325 KB) Open Access Article

  

Published online 13 February 2024

Understanding and Combatting COVID-19: Insights from Clinical Characteristics and Management Strategies

Bala Krishnan A 1, Vigneshwaran V 1, Tharani Kumar L 1, M. Shagar Banu 1

Timely analysis is crucial for understanding and combating global health crises like COVID-19 effectively

Abstract | Full Text | PDF (442 KB) Open Access Article

  

Published online 13 February 2024

Concerning Fungal Coinfections in COVID-19: Risks, Types, and Prevention – A Review

Bala Krishnan A  1, Vinoth Kumar K K 1, Tharani Kumar L 1, M. Shajini G Inbakani 1

The review highlights the alarming rise of fungal infections like Mucormycosis among COVID-19 patients, necessitating prompt diagnosis and care to prevent fatalities.

Abstract | Full Text | PDF (191 KB) Open Access Article

  

Published online 13 February 2024

Unprecedented Rise of Mucormycosis in COVID-19 Patients: Urgent Need for Protocol Adaptation and Awareness in India – A Review

Nithya A 1, Vinoth S V 1, Ashok Kumar M 1, Sindhu T 1

Mucormycosis in COVID-19 patients in India necessitates urgent updates in treatment protocols and public awareness

Abstract | Full Text | PDF (173 KB) Open Access Article

  

Published online 14 February 2024

Navigating COVID-19 Treatment: CT Scans, Steroids, and Medical Practice Challenges in India

Jayanthi E 1, C. Elayaraja 2, Priyadharshini S 2, Ashok kumar M 2

The review highlights India's struggle with COVID-19, emphasizing the need for tailored treatments amid rising cases, cautioning against unnecessary tests and misuse of medications.

Abstract | Full Text | PDF (173 KB) Open Access Article

  

Published online 14 February 2024

In vitro Cytotoxicity and Apoptotic Activity of Aquous, Chloroform and Methanol Extracts of Kiwi Fruit Actinidia deliciosa in MCF-7 cells

Kartheeswari 1, Archana C 1, Anupreyaa K 1, Saranya M 2

Assessment of A. deliciosa extracts' anticancer potential on MCF-7 cells offers insights for natural cancer medication development

Abstract | Full Text | PDF (411 KB) Open Access Article

  

Published online 15 February 2024

Impact of Dapagliflozin on Atherosclerosis through Inflammation and Oxidative Pathways

Zainab Abdlkadhim Aboshnin 1*, Safa Azhar Razzaq 1, Zahraa Ibraheim Jawad Shubber 2

Atherosclerotic patients need therapies targeting inflammation and oxidation. This study supports Dapagliflozin's use for clinical benefits in atherosclerosis.

Abstract | Full Text | PDF (360 KB) Open Access Article

  

Published online 15 February 2024

Association Between Low Bone Mineral Density in Hemophilia Patients and Musculoskeletal Function Impairments

Rasha Ibrahim Salman 1* , Khalid Mahdi Salih 1*, Nidal Karim Al-Rahal 2*

Hemophilia patients with low bone density (BMD) face higher risk with severe limitation of movement (LOM) and viral infections.

Abstract | Full Text | PDF (1007 KB) Open Access Article

  

Published online 16 February 2024

The Analysis of Hypertension Knowledge in Adults in Telafer City for Health Education and Intervention

 Mohammed Qassim Baktash 1* , Ali Ismael Sulaiman 1

Understanding hypertension in Telafer City adults is vital for preventing problems, guiding interventions, and managing the disease effectively

Abstract | Full Text | PDF (294 KB) Open Access Article

  

Published online 17 February 2024

The Analysis of Hematological Parameters CBC, ABO, NLR, and APTT and Its Implications on Haemophilic Patients with Low Bone Mineral Density

Rasha Ibrahim Salman 1* , Khalid Mahdi Salih 1, Nidal Karim Al-Rahal 2

The study determined a high prevalence of low bone mineral density in hemophilic patients, associated with elevated NLR and prolonged APTT.

Abstract | Full Text | PDF (1 MB) Open Access Article

  

Published online 17 February 2024

Efficacy of Paromomycin-Conjugated Nano Chitosan in Treating Entamoeba histolytica Infection in Mice

Hajar Falih Hishan Aldali 1*, Shatha Khudiar Abbas 1, Ahmed Naji Abd 1

Entamoeba histolytica causes widespread amebiasis. Chitosan-paromomycin nanoconjugates effectively treated infected mice, reducing liver enzyme levels, showing promising therapeutic potential.

Abstract | Full Text | PDF (1 MB) Open Access Article

  

Published online 17 February 2024

Anti-Cancer Activity of Allium Ascalonicum Ethanol Extract Against Human Hepatocellular Carcinoma Cell Line (HepG-2)

Geetha N B 1*, Chintala Venkatesh 1, Suresh M 1, Manikandan S 2

Allium ascalonicum might be a safer, more effective alternative to toxic chemotherapy for combating cancer with targeted potency.

Abstract | Full Text | PDF (283 KB) Open Access Article

  

Published online 18 February 2024

In vitro Anti-cancer Activity of Methanol Extracts of Kiwi Fruit, Actinidia deliciosa in HCT-119 Cells

Geetha N B 1, Priya R 1, Weslin D 1, Ashmi Christus A T 2

The study of anti-cancer properties of Actinidia deliciosa methanol extract in Colorectal cancer as effective treatments.

Abstract | Full Text | PDF (330 KB) Open Access Article

  

Published online 18 February 2024

Green Fungus Challenges in Post-COVID Health Landscape

Jeha J 1, Sudha S 1, Geetha N B 1, Benitta Sherine S 2

This review provides Green Fungus challenge in post-COVID situation. Early detection, hygiene, and research are imperative.

Abstract | Full Text | PDF (479 KB) Open Access Article

  

Published online 18 February 2024

Diagnosis of Chronic Brucellosis with Interferon-Gamma Quantification

Sarah Yahya Abdullah 1, Yasir Mufeed Abdulateef 2*, Sawsan Qahtan Taha Al-Quhli 3

This study showed the improvement of brucellosis diagnosis using interferon-gamma for better detection in chronic cases

Abstract | Full Text | PDF (399 KB) Open Access Article

  

Published online 19 February 2024

Epidemiological Analysis of Hepatitis B and C Viruses in Fallujah for Health Intervention and Disease Control

Ahmed Saadi khlaf 1*, Asif Hasan Abdulrazaq 2, Nawar Bahaa Abdulsahib 3, Manaf Akram Ismaell 3, Mustafa Asif Hasan 3

Investigating Hepatitis B and C in Fallujah revealed higher prevalence among males, aiding targeted interventions and public health initiatives.

Abstract | Full Text | PDF (251 KB) Open Access Article

  

Published online 19 February 2024

A study of Enhancing Fencing Skills with The Impact of Special Exercises on Kinetic Response and Attack Accuracy among Young Foil Players

Reem Mohammed Abdel Wahhab 1*

This study showed an improved exercise enhancing kinetic response, vital for fencing to optimize athletes' and their healthy performance.

Abstract | Full Text | PDF (207 KB) Open Access Article

  

Published online 19 February 2024

Determination of Demographic Liver Health with Giardia lambila Infection Analysis in Diyala

Noora Dhyaaldain Abed 1*, Shahad Abdul Jabbar Mohammed 2*

This study analyzed the Giardia infection as early detection for liver health intervention.

Abstract | Full Text | PDF (187 KB) Open Access Article

  

Published online 20 February 2024

Biofilms and Antibiotic Resistance Determination from Different Immunocompetent Patients with Salmonellosis

Mariam Ayad Abd 1*, Sawsan Q. T. Al-Quhli 2, Mahir Ali Jassim 3

This study discussed important information about antibiotic resistance and how harmful Salmonella bacteria are in Iraqi patients, helping to plan better public health measures.

Abstract | Full Text | PDF (692 KB) Open Access Article

  

Published online 20 February 2024

Cumin Extract Alters The Histology of Kidney and Duodenum in Adult Rabbit

Hussein B. Mahmood 1*,  Naseer  A. Al-Arubaye 1, Walaa F. Obead 1

This study showed the histological alterations of the kidney and duodenum due to excessive use of cumin.

Abstract | Full Text | PDF (480 KB) Open Access Article

  

Published online 22 February 2024

Factors Influencing Childhood Vaccine Refusal in Parents in Southern Malaysia and Its Effect on Health: A Cross-sectional Study

Sakina Ruhi 1*, Adlina Abdullatif 1, Jegathambigai R. Naidu 1, Hana Chen 1, Ayesha Syed 1, Danish Saud khan 2, Husni Ahmed Al Gosha 1, Sohayla Mohamed Elsherbini A 1, Mya Mya Thwin 1, Thin Thin Aung 1

This study sheds light on the important role that education and awareness play in overcoming vaccine hesitancy in Malaysia.

Abstract | Full Text | PDF (1 MB) Open Access Article

  

Published online 24 February 2024

The Effect of Brain Natriuretic Peptide, and Prothrombin Biomarkers in Pregnant Women With Gestational And Chronic Hypertension

Saif al deen M. Khatlan 1*, Wijdan I.A. Abd-alwahab 2

A study of gestational hypertension (GH) and chronic hypertension (HT) impact pregnancy, emphasizing the importance of monitoring brain peptide and biomarkers.

Abstract | Full Text | PDF (247 KB) Open Access Article

  

Published online 24 February 2024

Advancements of Polymer-Based Transdermal Drug Delivery Systems in Drug Bioavailability and Patient Compliance in United States

Hunny Dabas 1, Deepika Singh 1, Faraat Ali 2, Dipanjan Koley 1, Mohammed. Aslam 3, Esra Tariq Anwer Bayrakdar 3, Manvi Singh 1*

This review comprehensively discusses the transdermal drug delivery systems (TDDS) in the area of drug administration, for non-invasive, precise, and efficient delivery, overcoming oral limitations.

Abstract | Full Text | PDF (539 KB) Open Access Article

  

Published online 25 February 2024

In vitro Cytotoxicity of Activated Carbon from Musa Acuminate Fruit Peel Against HepG-2 Cells

Shanmugasundaram M 1, Prasath S 2, Geetha N B 2, Manikandan S 2

Activated carbon from Musa Acuminate exhibits potent inhibitory effects on HepG-2 cells via ROS-mediated MTD pathway, suggesting therapeutic potential against cancer.

Abstract | Full Text | PDF (519 KB) Open Access Article

  

Published online 26 February 2024

Spectrophotometric Determination of Vitamin C Using Indirect Oxidation with a New Organic Dye

Asmaa Ahmed Mohammed Alrashidy 1, Omar Adnan Hashem 1, Kalid Abdul-Aziz ALBadrany 1

The research focuses on the indirect determination of vitamin C in various pharmaceutical formulations, as well as in natural fruit samples and commercially available juices. For the first time, a novel organic dye was utilized in the process, and it was found that the method was indeed effective for the quantification of vitamin C in these products.

Abstract | Full Text | PDF (448 KB) Open Access Article

  

Published online 27 February 2024

Interplay And Causative Relationship Between Frailty And Atherosclerosis

Anastasia V. Poznyak 1*, Victoria A. Khotina 2, Roghayyeh Vakili-Ghartavol 2,3, Victor Y Glanz 2, Vasily N. Sukhorukov 2, Alexander N. Orekhov 2*

Frailty syndrome (FS) and cardiovascular diseases have a significant interaction, which impacts both the patient experience and how they are managed. Knowledge about the intricate associations between the two could provide a meaningful way towards developing targeted interventions.

Abstract | Full Text | PDF (1 MB) Open Access Article

  

Published online 27 February 2024

Neoatherosclerosis And Paleoatherosclerosis: Complications After Stenting

Anastasia V. Poznyak 1*, Victoria A. Khotina 2, Roghayyeh Vakili-Ghartavol 2,3, Victor Y Glanz 2, Vasily N. Sukhorukov 2, and Alexander N. Orekhov 2*

Enhanced imaging techniques help in the comprehension of neoatherosclerosis and paleoatherosclerosis, which are crucial for preventing stent failure and improving treatment approaches.

Abstract | Full Text | PDF (698 KB) Open Access Article

  

Published online 28 February 2024

A Post-Pandemic Insight on The Covid-19 and Pregnancy in Malaysia

Hana W. Jun Chen 1,*, Jegathambigai Rameshwar Naidu 1,*, Mohamed Najimudeen 1, Sakina Ruhi 1, Roy Rillera Marzo 2, Abdulah Y. Al-Mahdi 1, Haryati Anuar 1, Mohammed Faez Baobaid 1, Fatmawati Syamsu 3, Mohammed A. Abdalqader 4

In the midst of the Omicron surge, Malaysia is adjusting its approach, highlighting the importance of vaccination, updated guidelines, and community engagement as crucial means to mitigate the impact of COVID-19.

Abstract | Full Text | PDF (794 KB) Open Access Article

  

Published online 28 February 2024

Positive Coping and Community Resilience in Disaster Management for Flooding in Malaysia

Hana W. Jun Chen 1,*, Roy Rillera Marzo 2, Mila Nu Nu Htay 3, Sakina Ruhi 1,*, Sarah Mohd Zainal Abidin 1, Allistair Adam Nelson 1, Haryati Anuar 1, Jegathambigai Rameshwar Naidu 1, Irma Muslimin 4, Andi Salim 5

Recognizing the significance of coping mechanisms in fostering community resilience is essential for reducing the effects of flooding and enhancing health risks and disaster preparedness in Malaysia.

Abstract | Full Text | PDF (520 KB) Open Access Article

  

Published online 28 February 2024

Review on Angiogenesis Modulation by Natural Compounds as Therapeutic Potential and Mechanisms

Jegathambigai Rameshwar Naidu 1* , Sasidharan Sreenivasan 2, Sakina Ruhi 1, Hana W. Jun Chen 1, Sanjith Rameshwar Naidu 1, Danish Khan 3, Thin Thin Aung 1, Mya Mya Thwin 1, Husni Ahmed Al-Goshae 1, Subramanian Rammohan 1

Compounds derived from plants that have antiangiogenic effects could be used in the development of drugs that target this stage of angiogenesis.

Abstract | Full Text | PDF (205 KB) Open Access Article

  

Published online 28 February 2024

Determination of Vitamin K2, Lipoprotein (a) and N-Terminal pro Brain Natriuretic Biomarkers in Diabetic Hypertensive Patients with Acute Myocardial Infarction for Clinical Intervention

Ghaith Kamil Jawad 1*, Abdulsamie Hassan Alta'ee 2 , Oday Jasim Alsalihi 3

This study showed the biomarkers like NT-proBNP, Lp(a), and vitamin K2 might be valuable for AMI prognosis, aiding risk stratification and therapeutic decisions.

Abstract | Full Text | PDF (259 KB) Open Access Article

  

Published online 03 March 2024

Enhancing Breast Cancer Classification: A Deep Learning Approach with Outlier Detection With Egret Swarm Optimization Algorithm and Feature Selection Integration – A Systematic Review

S. Maria  Sylviaa 1*, N. Sudha 1

Early Breast Cancer diagnosis via data mining is crucial. Proposed methods achieve high accuracy, improving treatment outcomes for patients significantly.

Abstract | Full Text

  

Published online 28 February 2024

Vitamin D In Modulating Liver And Kidney Functions Following Cadmium Exposure In Vivo

Walid Theib Mohammad 1*, Ahmad Maher AL Sayeh 1, Fernando Jesús Plaza del Pino 2

The research determined how vitamin D plays a vital part in relieving kidney and liver damage from cadmium, thus having important implications for treatment.

Abstract | Full Text | PDF (211 KB) Open Access Article

  

Published online 03 March 2024

Wild Horse Optimizer and Support Vector Machine (SVM) Classifier Predicts The Heart Disease Converging Nature-Motivated Optimization and Machine Learning

Vishwanadham Mandala 1*, Srinivas Naveen Dolu Surabhi 2, V. R. Balaji 3, Dipak Raghunath Patil 4, Saiyed Faiayaz Waris 5, G. Shobana 6

Heart disease, responsible for millions of deaths annually, necessitates early detection. Machine Learning offers efficient, cost-effective diagnostic tools. The proposed Wild Horse Optimizer (WHO) and SVM classifier enhance heart disease forecasting, addressing critical healthcare needs.

Abstract | Full Text

  

Published online 04 March 2024

A Novel Framework of Hybrid Optimization Techniques for Contrast-Enhancement in Cardiac MRI Medical Images

Radhika R. 1*, Rashima Mahajan 1

Enhancing medical image contrast improves diagnosis accuracy. COA-SCSO optimizes parameters efficiently, ensuring clearer images and better patient care outcomes.

Abstract | Full Text

  

Published online 04 March 2024

Integrated Approach for ECG Signal Classification Using Fused Slantlet Transform and Autoregressive Features

 ALI Aalsaud 1*, Raghad Z. Yousif 2, 3

The novel ECG analysis method improves detection accuracy, is vital for early diagnosis of CVD, and potentially saves lives, especially in underserved regions.

Abstract | Full Text

  

Published online 04 March 2024

Modified VGG-19 Deep Learning Strategies for Parkinson's Disease Diagnosis - A Comprehensive Review and Novel Approach

Aruna Kokkula 1*, P. Chandra Sekhar 2, T. M. Praneeth Naidu 3

This review describes the upgraded ability to diagnose PD through deep learning and an altered VGG19 model, offering an accuracy rate of nearly 98%, reshaping the neurology treatment field.

Abstract | Full Text

  

Published online 05 March 2024

Synthesis, characterization and Antibacterial Evaluation of Novel Thiazolidine Derivatives

Shaima H. Abdullah 1*, Mahmoud M. Salih 1, Khalid, A. Al-Badrany 1*

Thiazolidine derivatives, synthesized from heterocyclic compounds, exhibit diverse biological activities, including antibacterial effects against various bacterial strains, suggesting potential pharmaceutical applications.

Abstract | Full Text

  

Published online 05 March 2024

Synthesis, characterization and Antibacterial Evaluation of Novel 1,3-Oxazepine Derivatives Using A Cycloaddition Approach

Farah M. Muhammad 1*, Bushra A. Khairallah 1*, K. A. Albadrany 1*

This study demonstrated a novel approach to the synthesis of oxazepine derivatives, key heterocyclic compounds with potential pharmacological applications.

Abstract | Full Text

  

Published online 06 March 2024

Determination of Health Service for Beneficiary Satisfaction: A Study of Maysan Child and Maternity Hospital

Saad Bader Abbas 1*, Rihab Al-Bedoui Bin Salem 2*

Research on health service satisfaction highlights vital insights for improving care, enhancing patient well-being, and optimizing resource utilization for better outcomes.

Abstract | Full Text

  

Published online 06 March 2024

Prolonged Formalin Exposure on Liver and Kidney Function Associated with TP53 Gene Expression in Quail Birds (Coturnix coturnix)

Iman Ibrahim Al hacham 1, Abdulrazzaq B. kadhim 2*, Eman F. Albaghdady 3

This study demonstrated a prolonged formaldehyde exposure in quails. It caused liver and kidney damage and affected gene expression as potential cancer risks.

Abstract | Full Text

  

Published online 06 March 2024

An intra-oral infection Halitosis and its Causes, Diagnosis, and Treatment Strategies – A Systematic Review

Noora Abdulrazzaq Naji 1*, Safa Ali Hamad 2, Samar Khalid Al-Adel 2, Hamsa Thabet Musa 2, Saja Sami Malik 2 

Halitosis, a prevalent issue, often remains untreated, causing social discomfort. Oral causes, especially bacterial buildup, necessitate effective dental management strategies.

Abstract | Full Text

  

Published online 07 March 2024

Healthcare Monitoring-based IoT framework for heart disease detection and classification

J. Shafiq Mansoor 1, Kamalraj Subramaniam 2

The review discused the Healthcare Monitoring based IoT framework (HM-IoT) and determined the security rate and classification accuracy.

Abstract | Full Text | PDF (1 MB) Open Access Article

  

Published online 07 March 2024

Advances in Periodontal Drug Delivery Systems and the Role of Probiotics in Periodontitis Treatment

Pratikshya Mohanty 1, Kalpita Bhatta 1*, Itishree Jogamaya Das 2,  Himansu Bhusan Samal 3*

This review discussed the periodontitis and its prevalence in gum inflammation and bone loss. Local drug delivery systems offer effective treatment, enhancing patient care.

Abstract | Full Text

  

Published online 07 March 2024

Immunological Significance of Meconium-Stained Amniotic Fluid with Complement Factors C3 and CD4 Levels for Pregnancy Health

Hanan Fawzi  Salman 1, Imtithal I. J. 1, Nagam Khudhair 1*

This research demonstrated the immune factors C3 and CD4 activity in amniotic fluid on prenatal health, which can diagnose the meconium-stained liquor complications early.

Abstract | Full Text

  

Published online 07 March 2024

Simulation and Modeling of Water Treatment Plant with GPS-X Software for Health and Water Quality

Nabaa Abdul- Kareem 1*, Jabbar H. Al-Baidhani 1

This research determined the quality of the Water Treatment Plant using special software that verified the function of water treatment plants to ensure health safety.

Abstract | Full Text

  

Published online 08 March 2024

Morphometric Study of Epicardium and Myocardium Thickness in Adult Human Hearts

Noor Abbas Ramadan 1*, Elham Majeed Mahmood 1, Saad Ahmed Mohammed 1

This study demonstrated the heart layer morphology, providing insights into cardiac anatomy, age, and gender influences, aiding clinical diagnosis and treatment.

Abstract | Full Text

  

Published online 08 March 2024

Inflammatory Modulation of Interleukin-17 and -23 in Long COVID Diabetic Patients

Esra Hassan Abd Ali 1*

The global COVID-19 pandemic disrupted daily life. This study demonstrated Long COVID's severity, especially in diabetic individuals, highlighting inflammation's crucial role.

Abstract | Full Text | PDF (245 KB) Open Access Article

  

Published online 08 March 2024

Postmenopausal Hormone, Hematology and Immune Modulation in Rheumatoid Arthritis Patients

Luma Qasim Ali 1, Firas Salih Abdulhadi 1, Ban Talib El-Haboby 1, Jamela Jouda 1*

This research determined the significant hematological, hormonal, and immunological changes in postmenopausal women with RA or SLE in compared to controls. This investigation had a high potential for therapeutic intervention.

Abstract | Full Text | PDF (279 KB) Open Access Article

  

Published online 08 March 2024

Novel Cardiac Biomarkers H-FABP and GPBB for Early Detection and Prognosis of Acute Myocardial Infarction

Hayder T Qaddoori 1*, Fatima Mallalah Mohammed 2, Ali Najm Abdullah 1

Novel cardiac biomarkers H-FABP and GPBB might improve the early diagnosis for myocardial infarction detection (within 1-4 hours of chest pain). H-FABP and GPBB proteins were investigated for identifying the heart muscle problems in this study.

Abstract | Full Text | PDF (401 KB) Open Access Article

  

Published online 29 February 2024

Genetic Variants of CYP2C8 Gene Predisposition to Type 2 Diabetes Risk

Saleh Abd-Qader Abed 1, Ammar Ahmed Sultan 1*

This study determined the genetic variations in the CYP2C8 gene which may illuminate predispositions to type 2 diabetes.

Abstract | Full Text | PDF (1 MB) Open Access Article

  

Published online 29 February 2024

Treatment of Hypothyroidism with Flavonoid Rich Extract of Fucus vesiculosus L Algae in Adult Rats

Somaya M. Eshtiwi 1*

Flavonoid extract from Fucus vesiculosus algae showed a thyroid activity modulator for the treatment of thyroid disorders.

Abstract | Full Text | PDF (1 MB) Open Access Article

  

Published online 08 March 2024

Elytrigia Repens Extracts Control Urban Mosquito Vectors with a Larvicidal Potential

Prakash D 1*, Mohideen Abdulkader M 1, Sakthivel D 1, Manju I 1, Sreenivasan K S 1, Manikandan S 2

This study demonstrated larvicidal activity to prevent mosquito disease and its spread, which might be due to insecticidal phytocompounds in the extract.

Abstract | Full Text

  

Published online 29 February 2024

A Retrospective Study of Outbreak and Vaccination on Measles Inflammation

Hayder Sudan Abbas Obaid 1, Ali Jaafar Mohammed 1, Laith A.I.K. Al-Kaif 2, *, Doaa Adil Abood 3, Younis A.K. Al-Khafaji 4

Understanding risk factors, vaccination rates, and surveillance effectiveness is crucial for developing targeted strategies to prevent measles infections in Iraq.

Abstract | Full Text

  

Published online 09 March 2024

Risks, Identification, and Antibiotic Susceptibility Against High Prevalence of Bacterial Infection in Contact Lens Solutions

Rana S. Hasan 1,  Sawsan M. Alomari 2, Roaa A. Thamer 3, Mohammed Fadhil Haddad 4*

This study determiend the microbial contamination in contact lens solutions for preventing eye infections and improving lens safety practices.

Abstract | Full Text

  

Published online 09 March 2024

A Rapid Continuous Flow Injection Analysis Method Development for Diphenhydramine Hydrochloride

Asma A. Gayed Al-Ani 1* , Nagham S. Turkey Al-Awadie 1*

Novel flow injection analysis improves Diphenhydramine HCL detection in pharmaceuticals with high sensitivity, speed, simplicity, and cost-effectiveness, enhancing industrial efficiency.

Abstract | Full Text

  

Published online 10 March 2024

Advances in Peer Teaching Methods in the Skill and Physical Development

Sura Gasid Hasan 1*

The study showed an innovative education for modern needs, improving basketball skills via peer teaching. Diverse methods motivate learners, enhancing health outcomes.

Abstract | Full Text

  

Published online 10 March 2024

Heavy Metal Accumulation and Phytochemical Profiling of Brassicaceae and Amaranthaceae for Phytoremediation and Medicinal Applications

Abdulilah Hanan Abdul Qader 1, Hind Hamid Hasan 2, Ashwaq Talib Hameed 3*, Hanan Y. Houmady 4, Rafraf abdul aziz abdul qader 5

The study provides valuable insights into heavy metal absorption by specific Iraqi wild plants, offering opportunities for phytoremediation and medicinal applications.

Abstract | Full Text

  

Published online 10 March 2024

Synthesis, Charecterization, Antibacterial and Cytotoxicity of Novel Metal Complexes Derived from Azomethine Ligand (Bis Azo-Schiff Base) In Vitro and In Silico

Hussein Abdulkadhim Hasan 1*, Saad M. Mahdi 1, Hanaa Addai Ali 2

This study demonstrated the synthesis of Schiff bases, like azo-Schiff metal complexes, showing therapeutic effects.

Abstract | Full Text

  

Published online 11 March 2024

High Fibroblast Growth Factor 23, Sialic Acids, and Albumin Modulation in Alzheimer’s Patients

Hashim Abdul-Sattar J. Al-Bajalani 1*

This study demonstrated a potential biomarkers and mechanisms underlying AD pathology for novel therapeutic strategies in future. Understanding serum biomarkers and oxidative stress in Alzheimer's disease (AD) is crucial for early diagnosis and targeted interventions.

Abstract | Full Text | PDF (245 KB) Open Access Article

  

Published online 11 March 2024

High HbA1C and Glycemic Control as Diabetic Nephropathy Etiology

Iman Kamel Aati 1*, Hawrra Jabbar Mohammed 2, Muhanad Mahdi Mohammed 3, Raya Najim Rasool Altimimy 4

High HbA1c levels correlate with diabetic nephropathy severity, urging comprehensive glycemic control for mitigating complications and improving diabetic outcomes.

Abstract | Full Text

  

Published online 11 March 2024

Control Mycotoxin Contamination in Tarasas Food Using A Lab Fermantion

Baraa Jameel Al-Assil 1,2*, Taghreed Abed Wahwah 3 

By utilizing LAB-mediated fermentation, this study demonstrated a natural and effective method for controlling mycotoxin contamination in traditional Tarasas food.

Abstract | Full Text

  

Published online 12 March 2024

Advances in Diagnosis and Treatment of Fabry Disease: A Review of Clinical Manifestations and Therapeutic Interventions

Mikhail A. Popov 1, Anastasia V. Poznyak 2*, Vladislav V. Dontsov 1, Julia Y. Kotalevskaya 1, Alexey B. Zulkarnaev 1, Vadim S. Tsy-plakov 1, Margarita A. Sazonova 3, Marina D. Sazonova 3, Elizaveta M. Pleshko 4, Victor Y Glanz 4, Vasily N. Sukhorukov 4, and Al-exander N. Orekhov 4*

This review discussed a treatment algorithm for advancing medicine, and patient outcomes of Fabry disease.

Abstract | Full Text

  

Published online 13 March 2024

The Role of Natural Compounds for Atherosclerosis Treatment: Lessons Learned from The Use of Curcumin

Anastasia V. Poznyak 1*, Victoria A. Khotina 2, Roghayyeh Vakili-Ghartavol 3, Victor Y Glanz 2, Vasily N. Sukhorukov 2, and Alexander N. Orekhov 2*

Curcumin has various pharmacological effects on atherosclerosis. This review discussed the promising therapeutic potential, of curcumin as anti-inflammatory, lipid regulation, and endothelial function for cardiovascular disease.

Abstract | Full Text

  

Published online 14 March 2024

Exploring the Link between Chronic Inflammation and Atherosclerosis-Endometriosis Association

Anastasia V. Poznyak 1,*, Vasily N. Sukhorukov 2, Igor A. Sobenin 2, Vladimir P Ofitserov 3, Anton Y. Postnov 2, Alexander N. Orekhov 2,*

Understanding shared inflammation mechanisms in atherosclerosis and endometriosis informs innovative interdisciplinary treatments, enhancing patient care and outcomes comprehensively.

Abstract | Full Text

  

Published online 15 March 2024

Advances in Cellular Models of Atherosclerosis

Anastasia V. Poznyak 1*, Victoria A. Khotina 2, Victor Y Glanz 2, Vasily N. Sukhorukov 1, Igor Alexandrovich Sobenin 2, and Alexander N. Orekhov 1

Atherosclerosis models, from 2D cultures to 3D tissue-engineered vessels, offer cost-effective avenues for drug screening and personalized medicine, advancing therapeutic discovery.

Abstract | Full Text

  

Published online 19 March 2024

A Study of Biochemical Markers in Uterine Cancer Diagnosis with Radiotherpay Treatment In Iraq

Wael Sahib Alnweny 1*, Mohammed Q. Almayali 1*, Mohammed A. Dakhil 2, Hiba Ali Numan 1, Yasir J. Abbas 3

Effect and investigation of radiotherapy of clinical biomarkers in Uterine Cancer patients.

Abstract | Full Text

  

Published online 20 March 2024

Study of Antibiotic Resistance in ESKAPE Bacteria Using β-lactamase and ESBL Genes

Hiba Ahmed Jawade 1*, Zahraa Yosif Motaweq 2, Hawraa Dheyaa Rasool 3,  Fatima Hassan Hussain 1

This study determined the resistance mechanisms of SKAPE group bacteria. Understanding this bacterial resistance mechanisms, particularly β-lactamase production, is crucial for effective treatment and infection control.

Abstract | Full Text

  

Published online 22 March 2024

High Growth Differentiation Factor-15 (GDF-15) in Rheumatoid Arthritis Patients Potential Risk for Cardiovascular Disease

Ghufran Abd Omran Abdulridha 1,2*, Mustafa Abdulkadhim Hussein 3, Suhad Rasheed Majeed 3

 

This study showed the high levels GDF-15, a clinical marker in rheumatoid arthritis, signified disease progression and heightened cardiovascular risk, implicating inflammation and tissue damage.

Abstract | Full Text

  

Published online 23 March 2024

Nanoparticle-Mediated Plasmid Curing in Combating Antibiotic Resistance in Pathogenic Bacteria

Muntaha R. Ibraheem 1*, Dhafar N. Al-Ugaili 2

Novel approach fights antibiotic resistance. Enhances DNA extraction efficiency. Eliminates resistance plasmids, aiding biotechnology. Highlights research needs for nanoparticle optimization and mechanism understanding.

Abstract | Full Text

  

Published online 25 March 2024

Nutritional Evaluation of Cassava Meal Components and Maize in Securing Feed and Food

Shahabuddin Ahmed 1,2, Mrityunjoy Biswas 2*, Atiqur Rahman Sunny 3, Farhana Irin 4, Md Faruk Hossain 5, Md Mostafizur Rahman 5, Md Abu Bakar Siddique 5, Md. Alauddin 6, Mrinal Kanti Debnath 2, Md. Pallo Hossain 2, Tufael 3, 7

This study assesses the nutritional composition of cassava and maize, pivotal crops for food and animal feed production globally, offering insights into dietary recommendations, agricultural practices, and food security measures in regions reliant on these staples.

Abstract | Full Text

  

These articles have been peer reviewed and accepted for publication. They are still in production and have not been edited, so may differ from the final published form.

Published online 07 January 2019

Modes of Anti-angiogenesis in Chemical Perspectives

Shan Arif a, b, Muhammad Imran a, b, Muhammad Adnan Iqbal a, b

In the current study, role of synthesized chemical pharmacores like Humulus lupulus, Hypericum perforatum, Panax ginseng, Coptis chinensis and Rheum palmatum (Varinska et al., 2010) as anti-angiogenesis has been compiled. 

Abstract


Published online 04 February 2019

Ethosomal formulation composed of standardized Orthosiphon stamineus extract and sophorolipid inhibits angiogenesis of melanoma in vivo

Mansoureh Nazari Vishkaei a, Mohamed Khadeer Ahamed Basheer c, Amin Malik Shah Abdul Majid a,b

SLOS vesicles can be considered for effective dermal therapeutic agent for the treatment of skin cancer.

Abstract


Published online 11 May 2019

Anti-GBM potential of Rosmarinic acid and its synthetic derivatives via targeting IL17A mediated angiogenesis pathway

Md Shamsuddin Sultan Khan A,C,E, Mohammad Adnan Iqbal B, Muhammad Asif A, Tabinda Azam B, Majed Al-Mansoub A, Rosenani S. M. A. Haque B, Mohammed Khadeer Ahamed Basheer C, Aman Shah Abdul Majid D, Amin Malik Shah Abdul Majid A,C,E*

Metal salts and base rosmarinates demonstrated potent anti-GBM efficacy as IL17A inhibitor with minimal toxicity.   

Abstract


Published online 15 May 2019

Ascorbate blocks acetylcholine- and bradykinin-induced vasodilatation in retinal vascular bed of the bovine isolated perfused eye

Li-xin XU A, Xiao-bo XIA B, Aman Shah Abdul Majid C, Dan Ji B

This study provides insight to EDHF-mediated vasomotor response, as well as various eye disorders caused by dysfunctional retinal arteries, like central retinal artery occlusion.

Abstract


Published online 24 June 2019

Evaluation of Safety and Efficacy of Labeesity® for Weight Management and Fatigue in an Obese Female Patient with Hypothyroidism: A Case Report

Aman Shah Abdul MajidA*, Elham FarsiB, Natesan VijayalakshmiC, Syarifah Aisya Syed AmranD, Mahibub Mahadmadsa KanakalE, Zarina Thasneem ZainudeenF*

Labisia pumila extracts based products will require robust studies to be conducted utilizing larger patient numbers and over extended periods of time to rule out any potential toxic effects.

Abstract


Published online 03 November 2019

Extract of Urgenia grandiflora inhibited breast cancer cell (MCF-7) proliferation and tumorgenesity

Ibrahim B. E. El Bashir A,B, Loiy Elsir Ahmed HassanC, Amin M. S. Abdul Majid D, Sakina Yagi A*

U. grandiflora could be a new source of chemotherapeutic for breast cancer.

Abstract


Published online 30 December 2019

Acute and Sub- chronic Toxicity Study of Encapsulation of Combine Plants Extract of Ficus deltoidea and Gynocthodes sublanceolata in Balb/c Mice Model

Rafida Kh. Ahmed A, M. Syarhabilahmad A, Midhat Nabil A, Fouad Saleih R. Al –Suede B,*

Oral treatment with encapsulated plant extract Ficus deltoidea and Gynocthodes sublanceolata did not appear adverse side effect and it is safe to use for therapeutic purposes.

Abstract


Published online 08 July 2020

Phytochemicals in Cancer with Special Emphasis on Ovarian Cancer

Meher U Nessa1,2, Md S Anwar1, Fazlul Huq3*

Reviews current literature on use of phytochemicals in prevention and therapy of ovarian cancer including mechanism of action.

Abstract


Published online 12 September 2020

Dose Dependent Synergism from Combination of Platinum Drugs with Curcumin against Colorectal Cancer Cell Lines

Hana Bali1, Jun Qing Yu1, Philip Beale2, and Fazlul Huq3

Ox in combination Cur demonstrated very high synergism against HT-29 and Caco-2 cell lines.

Abstract


Published online 13 March 2021

Immunomodulatory and Antiangiogenic Mechanisms of Polymolecular Botanical Drug Extract C5OSEW5050ESA OS Derived from Orthosiphon stamineus

Fouad Saleih R. Al-Suede1*, Mohamed B. Khadeer Ahamed1, Aman S. Abdul MajidSultan Ayesh Mohammed Saghir3, Chern E. Oon4, Amin Malik Shah Abdul Majid1,5*

C5OSEW5050ESA OS strongly curbs variety of angiogenesis modulators in vitro, ex vivo and in vivo.

Abstract


Published online 30 October 2021

Cannabis Sativa: A Remedy for Convulsion by Inhibition of GABAA Receptor and Significantly Delayed Onset of Seizure Latency and Death - An Experimental Validation and Molecular Docking

Ben Enoluomen Ehigiator1, SamuelKelechi Mobisson2, Iheanyichukwu Wopara3*, Chinonye Cynthia Chibuife1, Uwaezuoke Chukwuekele Awarajih3, Harrison Ogheneochuko Eruotor3

Abstract


Published online 10 November 2021

Immunomodulatory Effect of Tinospora cordifolia with Special Reference to Suppression of Cytokine Storm Induced in SARS-CoV-2

Aishath Thahuseen Waheed1, Thurga Ayavoo2,3, Karthikeyan Murugesan2,3,  Fouad Saleih R. AL-Suede4,5, Ashok Gnanasekaran2,3*

Development of anti-inflammatory herbal drug.

Abstract


Published online 11 November 2021

Phytochemicals with Direct and/or Indirect Anti-angiogenic Properties Against Various Cancer Types Focusing on Their Mechanism of Action

Ibrahim Al-deeb1,2,3, Julia Joseph1, Amin Malik Shah Abdul Majid2, Nozlena Abdul Samad1

Abstract


Published online 02 February 2022

Evaluation on Antibacterial Activity and Hepatoprotectivity of Rauwolfia serpentina

Gnanasekaran Ashok1,6*, Yukshna A/P Ramunaidu2, Fouad saleih R.AL-Suede3,4 Murugesan Karthikeyan1, Pugazhandhi Bakthavatchalam5, Sajeewa P.  Rathnayake6

The results of this study provide scientific evaluation of antibacterial activity and hepatoprotective effect of Rauwolfia serpentina which will be useful to researchers investigating the compounds with this potential and encouraging the development of new findings in this field.

Abstract


Published online 04 March 2022

A Systematic Review on Temporal Lobe Epilepsy Patients with Corona Virus Infection

Pugazhandhi Bakthavatchalam1, Fouad Saleih R.AL-Suede2,3, Sudarshan S.1*

Abstract


Published online 04 April 2022

Comparison of anti-inflammatory and analgesic effects of artocarpin-rich Artocarpus heterophyllus extract and artocarpin

Rizwan Rashid Bazmi1, Muhammad Asif2**, Hafiza Sidra Yaseen3, Pharkphoom Panichayupakaranant1,4*

The present study has an impact on overcoming the inflammation problem, which can lead to various types of chronic inflammatory diseases, using the artocarpin  & artocarpin-rich Artocarpus heterophyllus extract. The primary significance of this research is the achievement of preparation of a natural anti-inflammatory and analgesic agent using a green chemistry, which contributes to combat inflammation and analgesia. Furthermore, this method is practically used for industrial commercialization.    

Abstract


Published online 20 April 2022

Anti-tumor Activity of NuvastaticTM (C5OSEW5050ESA) of Orthosiphon stamineus and Rosmarinic Acid in An Athymic Nude Mice Model of Breast Cancer

Ashwaq Hamid Salem Yehyaa,*, Majed Ahmed Al-Mansoubb, Fouad Saleih Resq Al-Suedea, Siti Balkees Binti STN Hameed Sultana, Muhammad Asyraf Abduramana, Noor Amanina Azmic, Mufda jameel abedalhadi alrawashdehd, Seyedeh Fatemeh Jafarie, Amin Malik Shah Abdul Majida,f

Abstract


Published online 02 July 2022

Therapeutic Targeting on Death Pathways in Glioblastoma

Pavithra Suppiah1, Julia Joseph1, Rolla Al-Shalabi1, Nik Nur Syazni Nik Mohamed kamal1, Nozlena Abdul Samad1*

Abstract


Published online 24 August 2022

Hepatoprotective effect of Hydro-alcohol extract of Mimusops elengi root against antitubercular drug-induced hepatotoxicity in rats

Prakash Dabadi1, Fouad Saleih Resq AL-Suede2,3*, Chandrashekhar VM4*, Mallappa Shalavadi 4 , Ashok Gnanasekaran5

Development of therapeutics for the treatment of hepatotoxicity and oxidative stress  induced by ATDs

Abstract


Published online 17 September 2022

Targeting Microtubules by Phytoestrogens for the Treatment of Cancer: An Overview

Fan Xu1, Nozlena Abdul Samad1, Nurhuda Mohamad Ansor1*

In this review, we summarize reported effects of some phytoestrogens that bind directly to tubulin at various binding site and disrupt the microtubule dynamics, either by promoting microtubule polymerization or enhancing microtubule depolymerization.

Abstract


Published online 25 September 2022

Environmental and physiological angiogenesis in causing CVD with oxidative pattern

Md. Fakruddin1*, Md. Asaduzzaman Shishir2, Kumkum Rahman Mouree2, Shamsuddin Sultan Khan3

Oxidative stress plays critical role in angiogenesis and cardiovascular disease progression. Drugs targeting oxidative stress might provide a new treatment paradigm for related disorders.

Abstract


Published online 04 October 2022

Ferritin and High Sensitivity C-Reactive Protein (hs-CRP) may predict the COVID-19 patient’s fate

Zahra A. Kheudhier1*, Alaa K. Mossa2

Circulating biomarkers are an essential predictor for the prognosis of COVID-19-infected patients as they represent the severity of inflammation and immune status.

Abstract


Published online 04 November 2022

Prognostic Factors and Predictors of Mortality in Patients with Critical Limb Ischemia: A Current Clinical Perspective

Moniruddin Chowdhury1,2, Syeda Humayra2, Sohel Mahmud3, Yukihito Higashi4, YD Singh1

PAD and its impact in physical impairment or mortality.

Abstract


Published online 15 November 2022

Efficacy of Herbal Medicine as Adjunctive Therapy for Skin Cancer

Norbayu Mansor1, Julia Joseph1, Rola Al Shalabi1, Nozlena Binti Abdul Samad*1

Phytochemicals can be used for skin cancer prevention and treatment.

Abstract


Published online 22 November 2022

Immunoglobulin G Seroprevalence of Lassa Fever Virus Among Individuals Residing Along the Banks of River Niger in Anambra State, Nigeria.

Umezurike Kingsley Chimuanya1, Chukwuma Oluchukwu Mariagoretti1,2, Ochiabuto Mary Barbara1, Manafa Patrick Onochie1, Ntum Ifeanyichukwu Michael1, Chukwuma George Okechukwu1,2

LF-specific IgG seroprevalence among inhabitants of river banks in Anambra State, Nigeria

Abstract



Published online 24 December 2022

Cancer Immunotherapy in 2022 - End of the Beginning

Assoc. Prof. Dr. Toh Han Chong

Abstract




Published online 24 December 2022

Precision Medicine in Lymphoid Malignancies

Prof. Dr. Richard Rosenquist Brandell

Abstract





Published online 24 December 2022

Updates on Treatment of Gastroesophageal Cancers

Prof. Dr. Ho Gwo Fuang

Abstract


Published online 24 December 2022

Insights into Advanced Non-Small Cell Lung Cancer Patients with MET Alterations

Emeritus Prof. Dr. Liam Chong Kin

Abstract






Published online 24 December 2022

Targeted Delivery of Cisplatin Using RGD-Modified ZIF-90 as Delivery Vehicle

Emilia Abdulmalek1,2,*, Adamu Abubakar1,3, Kyle. E. Cordova4, Mohd Basyaruddin Abdul Rahman1,2,5

Abstract



Published online 24 December 2022

Molecular Modelling Analysis of Squamocin as Potential BCL-XL Anti-apoptotic Protein Inhibitor

Kaynat Khimani1, Mohd Faiz Abdul Ghani1,2, Rozana Othman3, Noraziah Nordin1,*

Abstract


Published online 24 December 2022

Differential Cell Cycle Arrest in Dihydroorotate Dehydrogenase (DHODH) Inhibition of Different Subtypes of Breast Cancer Cell Lines 

Muhammad Aiman Akmal Shahhiran1,2, Mohamad Fairus Abdul Kadir3, Nurshamimi Nor Rashid1,2, Shatrah Othman1,2,* 

Abstract


Published online 14 May 2023

Investigation Of Anti-Tumour Activity Of Orthosiphon Stamineus On Human Oral Squamous Cell Carcinoma

Shah kamal Bin Jamal Dina, Fouad Saleih Resq Al-Suedeb,c*,Farahnaz Aminid, Aman Shah Abdul Majide, JackTan Chun Keatd, Amin Malik Shah Abdul Majidf .

The potential of Nuvastatic in the treatment of oral squamous cell carcinoma.

Abstract


Published online 07 July 2023

Use of Neutralizing Monoclonal Antibodies and Its Outcome Measures in COVID-19 Patients

Moniruddin Chowdhury1,2, Syeda Humayra2, Taha Sulayman3, Keichiro Mihara4, P.K. Rajesh1

The use of monoclonal antibodies in Covid-19.

Abstract


Published online 23 July 2023

Diagnostic and differential efficacy of cyclin D1 and CA15-3 in breast cancer and benign breast tumors

Anmar R. Raheem1,2, Omar F. Abdul-Rasheed1*, Omar S. Khattab3, Ahmed Z. Abdulhameed4, Hussein A. Abid1,5*

Abstract


Published online 29 July 2023

Design, Synthesis, And Characterization Of New Schiff Bases For 3-Amino-1,2,4-Triazole-5-Thiolate Salt, Bearing Morpholine Ring And Biological Evaluation As Antibacterial Agents

Abeer Hussein Alia, and Mukhlif Mohsin Slaihimb*.

Antibacterial efficacy of new chemical compounds named benzaldehyde derivatives.

Abstract


Published online 12 August 2023

A review of the effects of Calophyllum spp. on cancer cells

Melissa Kilus1, Nozlena Abdul Samad1*, Shaari Daud2

Abstract


Published online 09 September 2023

Moringa oleifera's Effect on Colorectal Cancer

Rolla Al-Shalabi 1,2, Nozlena abdul samad 1*, Lim Vuanghao 1, Ibrahim Al Deeb 2, Julia Joseph 1

The therapeutic benefit of Moringa plant in cancer treatment

Abstract


Published online 03 October 2023

Unlocking Nature’s Treasure Trove: Exploring Microorganisms for Novel Bioactives

Tasbir Amin1, Abu Bakar Karim1, Israk Iram Oyshe1, Amana Hossain1, Tafsir karim1, Jinath Sultana Jime1, Nayeema Bulbul1, Md. Asaduzzaman Shishir2, Ashrafus Safa3, Md. Fakruddin1*

Abstract


Published online 16 October 2023

Optimizing The Protocol For Extraction Of Bioactive Components From Hibiscus Sabdariffa With Potent Antioxidant Activity

Nur Royhaila Mohamad *1, Farrah Payyadhah Borhan 2, Mohd Shahrizi Razali 3, Roswanira Abdul Wahab 4

Utilize statistical methods to determine which different variables impact the response to the extraction of roselle.

Abstract


Published online 21 October 2023

Antioxidant Potential of Calophyllum gracilentum: A Study on Total Phenolic Content, Total Flavonoid Content, and Free Radical Scavenging Activities

Nurr Maria Ulfa Seruji1, Vivien Jong Yi Mian1*, Nor Hisam Zamakshari2, Thiruventhan Karunakaran3, Lee Feng Koo4, Wong Tze Jin4, Chan Thye Huat5

Study of potential Therapeutic activity of Calophyllum herb.

Abstract


Published online 22 October 2023

The way of cholesterol in atherogenesis: from the main enemy to complex biomarkers

Anastasia V. Poznyak 1*, Victoria A. Khotina 2, Mikhail A. Popov 3, Alexander D. Zhuravlev 2, Vasily N. Sukhorukov 2, Alexander N. Orekhov 2*

Abstract


Published online 02 November 2023

Knowledge and Self-Management Practice Among Diabetic Patients from the Urban Areas in Bangladesh

Md. Jubayer Hossain1, Syeda Tasneem Towhid1,2* , Sumona Akter1 , Muhibullah Shahjahan1, Tilottoma Roy1, Bithi Akter1, Tanjum Ahmed Nodee1

Abstract


Published online 11 November 2023

Inhibitory Activity of Enzyme Α-Glucosidase Ethanol Extract Combination Of Mareme Plant (Glochidion arborescens (Müll. Arg.) Boerl.) Leaves And  Sala Plant (Cynometra ramiflora Linn) Leaves

Haryoto1*, Alysa Vivi Arnida1, Peni Indrayudha1, Cita Hanif Muflihah1, Khong Heng Yen2

Mareme and Sala leaves mix may be a strong blood sugar blocker, but it contains useful chemicals for potential medical research.

Abstract


Published online 12 November 2023

Stromal Interaction Molecule-1 (STIM1): Orchestrating Calcium Signaling in Cancer and Hematologic Malignancies

Rabiatul Basria S. M. N. Mydin1, Adam Azlan1, Eman Salem Saeed Algariri,1 Nur Azuar Abdul Rahim2,3, Emmanuel Jairaj Moses1, Narazah Mohd Yusoff1

Abstract


Published online 14 November 2023

Antiangiogenic and Anticancer Potential of Supercritical Fluid Extracts from Nutmeg Seeds; In vitro, Ex vivo and In silico studies

Sawsan S. Al-Rawi1*, Ahmad Hamdy Ibrahim2, Marthad A. Hamde3, Dinesh Babu4, Mansoureh Nazari5, Mohd Omar Ab Kadir6, Aman Shah Abdul Majid7, Amin Malik Shah8

Abstract


Published online 23 November 2023

Comparative Analysis of Epstein-Barr Virus EBNA-2 Sequence Variation in Nasopharyngeal Carcinoma and Other EBV-Related Tumors

Lee Wei Zheng1,2, Rabiatul Basria S. M. N. Mydin1*, Adam Azlan1,5 and Muhamad Yusri Musa3,4

Abstract


Published online 24 November 2023

Hepatitis C and Atherosclerosis: Inflammatory Interplay

Anastasia V. Poznyak 1*, Ludmila V Nedosugova 2, Vasily N. Sukhorukov 3, Alexandra A. Melnichenko 3, Elizaveta M. Pleshko 3 and Alexander N. Orekhov 3

A review of the relationship between HCV infection, inflammation, and cardiovascular pathologies.

Abstract


Published online 24 November 2023

Effect of Plumbago zeylanica on Analgesia and Arthritis

Subasini Uthirapathy1*

The inhibition activity of PZ on carrageenan-induced arthritis, humoral and cellular immunity, and pain and inflammation.

Abstract


Published online 27 November 2023

Pomegranate Juice Attenuates Anti-ulcer in Indomethacin-induced Peptic Ulcer

Ali Omar Yaseen 1, Payam Jamal Muhamed 1, Hacer Haltas 1 , Subasini Uthirapathy 1*

Study on using pomegranate juice supplements to treat ulcers caused by pain medications.

Abstract


Published online 27 November 2023

Characterization of Essential Oil Composition of Syzygium aromaticum Linn. (Clove) by GC-MS and Evaluation of its Antioxidant Activity

Javed Ahamad 1*

The study of Clove essential oil as an antioxidant drug.

Abstract


Published online 05 December 2023

Gymnemagenin a Promising Drug Candidate for Management of Hyperglycemia: In-Vitro and In-Vivo Study

Javed Ahamad1, Saima Amin2, Kamran J Naquvi1, Showkat R Mir3*

Study of Gymnema sylvestre plant for the treatment and management of diabetes.

Abstract


Published online 08 December 2023

Current Perspective on Pesticides: Their Classification, Behaviour, Potential Use and Toxic Effects

Adil Ahamad1*, Javed Ahamad2, Mohd. Javed Naim2

Monitoring the use of pesticide and analyzing their acceptable levels for human health.

Abstract


Published online 04 December 2023

Drug Repositioning and Response Detection Based on Randomized Control Trials for Cancer Treatment - A Review

Aman Chandrakar 1, Chetan Kumar Sonkar 2

The cancer treatment will be accelerated through drug repositioning.

Abstract


Published online 01 January 2024

Black Soldier Fly Larvae Feed with Fermented Bamboo Culms Enriched with Lactic Acid Bacteria

Nurul Azila Abdul Razak 1, Ang Chung Huap 1*, Vivien Jong Yi Mian 1, Siti Nor Ain Seri Masran 2

The study of plant-based protein source as  the nutrition of Black soldier fly

Abstract


Published online 05 December 2023

A Review of Potential Roles for Micro RNAs as Drugs Sensitivity Biomarkers in Breast Cancer

Monika Barsagade 1*, Ravi kishore Agrawal 2*

The role of miR-202's in discovering biomarkers for early diagnosis and improving therapeutic strategies for breast cancer.

Abstract


Published online 06 December 2023

Evaluation of Cardiac Reserve Using Echocardiography for The Detection of Mild Cardiac Dysfunction in Mice - A Review

Sanjay Kumar Mire 1, Deepak Kumar Sahu 2

Echocardiography-based strain imaging offers early detection of cardiac abnormalities, treatment, and research strategy. 

Abstract


Published online 06 January 2024

Determination of Active Biomarkers and the Antioxidant and Antibacterial Potential of Standardized Zygophyllum spp Extract

Mostafa Alamholo 1

Identification of active compounds in medicinal plants to control resistant bacteria

Abstract


Published online 07 January 2024

Evolution of Genes and Transcripts Modifies Drug Sensitivity in Cancer Cell Lines - A Review

Krishna Sahu 1, Urvashi Jain 2

Dynamic genomic and transcriptomic evolutionary modeling guides cancer genetics, transforming treatment by predicting drug sensitivity in genomics.

Abstract


Published online 07 December 2023

Discovering Novel and Old Drug Targets in Oral Cancer Stem Cells Using bio-inspired methods - A Review

Vijay Kumar Jaiswal 1, Mahendra Kumar Verma 2

Evolutionary Computation Network for Drug Repositioning reveals oral cancer stem cells, informing targeted therapies for treatment.

Abstract


Published online 07 December 2023

Impedimetric Sensor Aided by Polydopamine Nanoparticles for Label-Free Detection of Breast Cancer Cells - A Review

Bhuneshwari Dewangan 1, Naina Bhoyar 2

 

A review of polydopamine sensor in breast cancer diagnosis.

Abstract


Published online 08 December 2023

Analyzing The Risks, Benefits, and Therapeutic Potential of Cannabis And Cannabinoids in Tumor Therapy - A Review

Poorti Sharma 1*, Lukeshwari Sahu 1

Study explores Cannabis use by metastatic tumor patients, analyzing active components, addressing gaps in research, and promoting informed medical guidance.

Abstract


Published online 08 December 2023

Review on Health And Quality of Life of Elderly People: A Meta-Analysis from The Medical and Health Sciences

Ashish Agarwal 1*, Sachin Pradhan 2

An IoT-based system enhancing elderly care, emphasizing QOL, independence, and support, aiding healthcare development for seniors' well-being.

Abstract


Published online 08 December 2023

The Clinical, Histological, and Immunohistochemical Features of Bone Metastases - A Review

Ragini Patel 1*, Yogendra Sahu 2

A deep learning model to trace bone metastasis origins, addressing challenges in diagnosis and emphasizing therapeutic implications and monitoring.

Abstract


Published online 12 December 2023

Hydrophobin-Coated Noisomes as Drug Carriers in Lung Cancer Cells - A Review

Srishti Namdeo 1, Chandrapratap Dhimar 2

Targeted nanoparticle delivery to Lung Cancer Cells, using hydrophobin-coated niosomes, addressing multidrug resistance, and enhancing treatment efficacy.

Abstract


Published online 14 December 2023

Predictive Modeling of The Chronic Pain-Induced Depression in Old Adults Based on Music Intervention

Birendra Kumar Sahu 1, Chiranjeev Singh 2

This research addresses the prevalent issue of chronic pain in older adults, proposing a novel Predicting Chronic Pain-based Music Intervention model for personalized, effective treatment, showcasing promising results for mental well-being improvement.

Abstract


Published online 14 December 2023

Analysis of Semi-Rural and Urban Hypertension Prevalence Using WHO Measures

Sumit Kumar Agrawal 1, Tripti Dewangan 2

Guiding a tailored intervention and strategy to advance global hypertension management

Abstract


Published online 17 December 2023

Menopause-Related Insomnia, Cognitive, Behavioral, and Mindfulness-Based Treatments

Venu Anand Das 1, Jitendra Sinha 2

The study explores challenges in treating menopausal symptoms, introducing the Menopause-based Treatment Study Framework (MTSF) for more effective and enduring resolution.

Abstract


Published online 17 December 2023

Epidermal Growth Factor Receptor and Double-Imprinted Nanoparticles for Targeted Cancer Drug Delivery - A Review

Lakhan Lal Kashyap 1, Harish Jaiswal 2

A targeted drug delivery approach, using double-imprinted nanoparticles and EGFR-SVM, to enhance anticancer drug effectiveness selectively in tumor cells.

Abstract


Published online 19 December 2023

Identifying Thyroid Dysfunction Using Standard Laboratory Testings – A Systematic Review

Vinay Jaiswal 1, Prachi Gurudiwan 2

A ML-TDI model for thyroid dysfunction identification, addressing underdiagnosis challenges and emphasizing the importance of comprehensive assessment in care.

Abstract


Published online 21 December 2023

Screening for Oral Cancer Using Brush Biopsies and DNA Image Cytometry - A Review

Pranjali Verma 1,  Shikha Kumari Rajak 2

A non-invasive DNAIC-DCNN for accurate oral cancer diagnosis, offering targeted medications for effective treatment.

Abstract


Published online 21 December 2023

The Effect of Naturally Occurring Dietary Chemicals and Food-Borne Mycotoxins on DNA Methylation and Cancer - A Review

Moniza Nurez Khan 1, Naresh Chandravanshi 2

The critical impact of Food-Borne Mycotoxins (FBM) and Artificial Light At Night (ALAN) on DNA methylation, influencing cancer risk and disease outcomes.

Abstract


Published online 22 December 2023

Analyzing the Influence of Initial Diagnosis on Interpersonal Problem Trajectories in Residential Treatment for Eating Disorders - A Review

Hemlata Dewangan 1, Neetish  Kumar 2

A systematic review of post-residential treatment outcome for eating disorders

Abstract


Published online 25 December 2023

Physical Activity Correlates With The Aging Process in Seniors Broadly - A Review

Bhuneshwari Dewangan 1, Naina Bhoyar 2

A review of a correlation between physical activity, life satisfaction, and aging in the senior age group with Internet of Things (IoT) based Physical Activities (IoT-PA) model

Abstract


Published online 29 December 2023

Brain-Computer Interfaces Can Significantly Improve The Quality of Life for Aged People - A Review

Sanjay Kumar Mire 1, Deepak Kumar Sahu 2

A non-invasive Brain-Computer Interfaces (BCIs) and IoT-based Smart Home Technology can enhance memory, focus, and aged people's quality of life.

Abstract


Published online 08 January 2024

Gut-Brain Connection; IBS linked to Anxiety, Quality of Life, and Academic Performance in Undergraduate Students

Mohamed Sadeq Al-Ibrahim *1, Ahmad Hamdy Ibrahim 2, Sawsan S. Al- Rawi *3, Bayram Dawod Ahmed 4, Nalan Linda Fraim 5

Chronic stress affects many physiological processes including immunity and angiogenesis. IBS impacts anxiety, quality of life, and academic performance of undergraduate students.  

Abstract


Published online 08 January 2024

A Review of Dipeptidyl Peptidase-4 (DPP-4) and its potential synthetic derivatives in the management of Diabetes Mellitus

Mohd. Javed Naim 1

To establish potential DPP-4 inhibitors. 

Abstract


Published online 11 January 2024

Polycystic Ovarian Syndrome: An Overview with Special Consideration to Its Oral and Pediatric Clinical Manifestations

Zeba Saleem 1, Abiha Ahmad Khan *1, Syeda Aamena Naaz 1 and Mohd. Javed Naim 2

Highlighting the oral and pediatric manifestation of PCOS. 

Abstract


Published online 12 January 2024

An In-Depth Analysis of Microorganisms Linked to Various Forms of Hospital-Acquired Infections: A Systematic Review

Nadirah Yusof 1,  Rabiatul Basria S. M. N. Mydin 1,2*, Chandrarohini Saravanan 2,3,4, Nor Hazliana Harun 2,5, Siti Salmah Noordin 5

The study aims to provide a detailed understanding of the microorganisms involved in different types of HAIs, such as surgical site infections, urinary tract infections, bloodstream infections, and respiratory tract infections.

Abstract


Published online 12 January 2024

Platelet Implication in Atherosclerosis Pathogenesis

Anastasia V. Poznyak 1*, Varvara A. Orekhova 1, Vasily N. Sukhorukov 1, Alexandra A. Melnichenko 2, Elizaveta M. Pleshko 2, Alexander N. Orekhov 1

Platelets' vital role in health, thrombosis, atherosclerosis; therapy's ongoing clarification.

Abstract


Published online 15 January 2024

Maternal Hypercholesterolemia is a Significant Risk Factor for Atherogenesis – A Systematic Review

Anastasia V. Poznyak 1*, Victoria A. Khotina 2, Vasily N. Sukhorukov 2, Nikolay Sadykhov 2, Anton Y Postnov 2, and Alexander N. Orekhov 2*

Maternal hypercholesterolemia during pregnancy influences fetal development, leading to lasting atherosclerotic changes, emphasizing preventive strategies to reduce future cardiovascular disease burdens.

Abstract


Published online 16 January 2024

An Educational Intervention to Improve Adverse Drug Reactions Reporting Among Healthcare Practitioners in Selected Pediatric Hospitals in Iraq

Bootan A. Salih 1,*, Omer Q. Allela 2, Raad A Kaskoos 3, Javed Ahamad 4

The main goal of the study is to design an intervention program to increase knowledge attitude and practice of healthcare practitioners towards pharmacovigilance.

Abstract


Published online 17 January 2024

Innovative Piperidine-Catalyzation in Protecting Carbonyl Compounds with Implications for Angiogenesis and Inflammation

Mukhlif Mohsin Slaihim 1*, Luay Ali Dhahi 1, Abeer Hussein Ali 1

Introduced piperidine-catalyzed protection in aldehydes, guiding anti-cancer compound optimization.

Abstract


Published online 18 January 2024

Effect of Toll-Like Receptor 9 (TLR9) in Breast Cancer Risk, Along with Hormonal Effects in Patients Receiving Radiotherapy

Asra'a Adnan Abdul-Jalil 1, Marrib N. Rasheed 2, Rana H. Hamoode 3

TLR9 rs187084 polymorphisms crucial in Iraqi women's breast cancer susceptibility.

Abstract


Published online 19 January 2024

Optimizing Fast-Dissolving Tablets of Ketotifen: Impact of Sodium Bicarbonate and Citric Acid in Formulation and Evaluation

Rozhan Arif 1, Sharad Visht 1*, Ali Omar Yassen 1, Sana Sirwan Salih 1

Formulating ketotifen fast-dissolving tablets (FDT) tackled poor bioavailability challenges, emphasizing sodium bicarbonate's pivotal role for rapid tablet disintegration, highlighting FDT viability for asthmatic treatment.

Abstract


Published online 20 January 2024

Significance of Serum Biomarkers in Early Diagnosis of Hepatocellular Carcinoma in Patients with Fisher Groups

Tufael 1, Auditi Kar 2, Vijay Jagdish Upadhye 3*, Amith Dutta 4, Md Royhanur Islam 5, Abdus Sattar 6, Md. Eunus Ali 7, Julakha Akter 8, Kaniz Fatima Bari 9, Md. Tahsin Salam 10, Palash Chandra Banik 11, Md Shamsuddin Sultan Khan 12, Atiqur Rahman Sunny 6*

The research addresses a crucial gap by linking the unique lifestyle and stressors in fisher groups to hepatocellular carcinoma.

Abstract


Published online 20 January 2024

Advancing Therapeutic Efficacy of Star Anise Oil with (Illicium verum) Nano-Emulsion Formulation

Sharad Visht 1, Sana Sirwan Salih 1, Belan Azad Ibrahim 1, Daniah Issa Ismael 1, Serwa Falah Abdalwaheed 1, Omji Porwal 1

Star anise oil-based nano-emulsions' extraction, purification, and formulation processes to improve therapeutic efficacy of drug substances

Abstract


Published online 20 January 2024

A Review of Healing Potential of Indian Flora: An Ethnopharmacological Evidence of Wound Healing Activity

Rasmita Jena 1,2, Durga Madhab Kar 1*, Sovan Pattanaik 1, Bhisma Narayan Ratha 3

This review emphasizes the rich potential in traditional practices, offering valuable insights and solutions to current healing challenges.

Abstract


Published online 21 January 2024

Renal and Hepatic Toxicity of Alpha-Cypermethrine Pesticide Used on Agricultural  Farmers Living Closed to Tigris river, Iraq

Sarhan Rashid Sarhan 1*,   Mohammed H.M. Merah 2

ALP, ALT and AST enzymes increased significantly when directly exposed to this pesticide as a result of its effect on kidney and liver functions.

Abstract


Published online 21 January 2024

Therapeutic Effects of Esomeprazole, Curcumin, Chitosan, and Curcumin-Chitosan Mixture on Ethanol-Induced Gastric Ulcer in Female Rats

Jenan Mahdi Jawad Al-kawaz 1*, Fakhir Magtoof Al-Zubaidy 2**, Hussein Jassim Obaid Al -Harbi 1***

Evaluate the healing effects of esomeprazole, curcumin, chitosan, and a curcumin-chitosan mixture on gastric injuries induced by ethanol in rats.

Abstract


Published online 21 January 2024

Synthesis And In-Silico Anti-Cancer Potential of N-Aryl-Keto-Nitrone As A Spin Adducts

Rita S. Adam 1*

Advancing spin trapping chemistry through the introduction of effective linear keto-nitrones, expanding applications and refining practical use.

Abstract


Published online 22 January 2024

Effect of Metformin and Vitamin D Supplementation on Metabolic and Hormonal Profiles in Polycystic Ovary Syndrome Women: A Follow-Up Study

Zainab Nur-Eldeen Aziz 1*, Basil O. Saleh 1

Positive Impacts of Metformin and Vitamin D Supplementation on Polycystic ovary syndrome (PCOS) Women

Abstract


Published online 22 January 2024

Anti-Cancer Study of Carvacrol in Hypoxic-Induced Colorectal Cancer Cell

Aumaima Tariq Abed 1,2* ,  Ahmed MH AlMudhafar 1 , and Najah R Hadi 1

Effect of carvacrol on proliferation and migration of hypoxic SW480 cancer cells

Abstract


Published online 22 January 2024

Effect of Steroid Treatment on Tissue Damage Markers in Diabetic Patients

Mohammed Shakir Ali 1*, Ali Al-Shammari 1, Qutaiba A. Ismael 1, Obaida Amer Imran 1, Mohammed H. Al-Bayati 1

This research showed how diabetes and steroids worsen effects, providing a better understanding of the pathophysiology processes.

Abstract


Published online 22 January 2024

Synthesis, Characterization and In Vitro Anti-cancer  Properties of Cationic Gemini Surfactants with Alkyl Chains in Human Breast Cancer

Anwar Shalan F. 1*, Samah Hussein Kadhim 1

Anti-cancer activity of Gemini surfactants in human breast cancer cells

Abstract


Published online 22 January 2024

Impact of Various Contraceptive Methods on Immunological Profiles in Women: A Serological Analysis in Diyala Governorate

Shaymaa Mohammed Alwan 1, Maha Falih Nazzal 2, Inaam Faisal Mohammed 3

Abstract


Published online 22 January 2024

Two Forms of C-Reactive Protein and Their Implication for Atherogenesis: Focus on Monomeric Form

Anastasia V. Poznyak 1*, Victoria A. Khotina 2, Anton Y Postnov 2, Vasily N. Sukhorukov 2, Nikolay Sadykhov 2, Alexander N. Orekhov 2*

A review on inflammatory protein in atherosclerosis progression.

Abstract


Published online 22 January 2024

Machine Learning-Based Enhanced Drug Delivery System and Its Applications – A Systematic Review

Abhijeet  Madhukar Haval 1*, Kumar Shwetabh 1, Sushree Sasmita Dash 1

Machine Learning (ML) transforms drug development, predicting drug properties, targets, interactions, and facilitating efficient exploration for researchers and pharmaceutical companies.

Abstract


Published online 23 January 2024

A Systematic Review of Advanced Approaches in Wound Healing: Simvastatin Polymeric Nanoparticles and Postbiotics Innovation

Chandrapratap Dhimar 1*, Krishna Sahu 1, Moniza Nurez Khan 1

Utilizing innovative postbiotics and Simvastatin Polymeric Nanoparticles, wound research accelerates healing, promising improved treatment with minimal inflammation.

Abstract


Published online 23 January 2024

A Review of Modeling Checkpoint Blockade Therapy and Therapeutic Strategies in Integrative Pharmacological Approach for Metastatic Breast Cancer

Prachi Gurudiwan 1*, Ragini Patel 1, Urvashi Jain 1

Quantitative Systems Pharmacology models immune processes in breast cancer, aiding personalized treatment by identifying biomarkers, resistance mechanisms, and therapeutic options

Abstract


Published online 23 January 2024

In vitro Antibacterial Activity of Seribu kuman Leaf (Rhinacanthus nasutus (l.) Kurz) Extracts Against Staphylococcus aureus and Pseudomonas aeruginosa

Betty Fitriyasti 1*, Siska Ferilda 2, Widia Sari 3, Muhammad Rizki Saputra 4, Heng Yen Khong 5*

Rhinacanthus nasutus extract inhibits the growth of Staphylococcus aureus and could serve as an alternative in treating infections caused by S. aureus.

 

Abstract


Published online 24 January 2024

The Characterization of Acute Myeloblastic Leukemia-M2 Cell Lines with Suppressed Stromal Interaction Molecule 1 (STIM1) and its Impact on Calcium/Reactive Oxygen Species Profiles

Eman Salem Algariri 1,2, Rabiatul Basria S. M. N. Mydin 1*, Emmanuel Jairaj Moses 1, Nur Arzuar Abdul Rahim 3, Narazah Mohd Yusoff 3

STIM1's potential role in promoting AML-M2 cell survival by regulating calcium/ROS interactions, as well as KRAS/MAPK and Akt-related pathways

Abstract


Published online 24 January 2024

A Comprehensive Review on Cardiovascular Disease Detection, Risk Assessment, And Treatment Using A Network Pharmacology Model

Vijay Kumar Jaiswal 1*, Monika Barsagade 1, Jitendra Sinha 1

Contribution to advancing diagnostic methods, proposing innovative treatment approaches, and demonstrating the effectiveness of pharmacist-led preventive strategies for improving population health, reducing the economic burden of cardiovascular diseases, and showing more personalized and mechanism-based approaches in healthcare.

Abstract


Published online 24 January 2024

Advancements in Ocular Vascularization Analysis Using Deep Learning Techniques – A Systematic Review

F Rahman 1*, Akanksha Mishra 1, Sushree Sasmita Dash 1

This review shows an advanced machine learning method for efficient segmentation and classification of blood vessels in medical images, revolutionizing diagnostic precision.

Abstract


Published online 25 January 2024

Advances of AI-driven Drug Design and Discovery in Pharmaceuticals - Review

Dev Ras Pandey 1*, Sushree Sasmita Dash 1, Akanksha Mishra 1

The application of AI in pharmaceuticals holds the promise of personalized therapies, streamlined production, and improved market strategies, making it an indispensable tool for the future of drug development.

Abstract


Published online 25 January 2024

Smart Wound Monitoring and Healing Assessment System With Deep Learning Methods - A Systematic Review

Abhijeet  Madhukar Haval 1*, Akanksha Mishra 1, Sushree Sasmita Dash 1

Wound features impact healing; indicators like temperature, oxygen levels, and moisture influence the process. This review shows and effective at-home wound monitoring with biosensors.

Abstract


Published online 26 January 2024

Advances in Image Processing Methods for Breast Cancer Diagnosis and Classification Using A Hybrid Machine Learning – A Systematic Review

Priya Vij 1, Sushree Sasmita Dash 1, Akanksha Mishra 1

Advanced integration of deep learning (AlexNet) and SVM-RBF for breast cancer diagnosis surpasses existing models, ensuring precise and reliable early detection.

Abstract


Published online 26 January 2024

A Pharmacy System Integrated with A Machine Learning Algorithm for Cardiovascular Disease Prediction

Kumar Shwetabh 1*, F Rahman 1, Sushree Sasmita Dash 1

The review explores an inclusive ML structure, vital for efficient CVD forecasting. The proposed model showcases superior accuracy, emphasizing the need for comprehensive predictive algorithms in cardiovascular health research.

Abstract


Published online 05 February 2024

Vitamin D Deficiency As A Contributor To Atherosclerosis Development – A Review

Anastasia V. Poznyak 1*, Victoria A. Khotina 2, Alexandra A. Melnichenko 2, Victor Y Glanz 2, Vasily N. Sukhorukov 2, and Alexander N. Orekhov 2*

Vitamin D deficiency and cardiovascular diseases, explores role in inflammation, oxidative stress, and vascular calcification

Abstract


Published online 08 February 2024

Repurposing Drugs for Overcoming Therapy Resistance in Colon Cancer – A Review

Mahdi Darvishi 1, Amir Mohammad Chekeni 2, Mohammad Fazelhosseini 1, Zeenat Iqbal 3*, Mohd Aamir Mirza 3*, Mohammed Aslam 4, Esra Tariq Anwer Bayrakdar 4

Oncology research seeks new therapies for aggressive CRC, utilizing repurposed drugs for accelerated and safer treatment approaches.

Abstract


Published online 09 February 2024

A Review of 3d Printing Model of New Blood Vessel Formation For Pharmaceutical Applications

Nidhi Mishra 1*, Priya Vij 1, Akanksha Mishra 1

Innovative synthetic blood vessels offer promising solutions for cardiovascular diseases, providing safer, more accessible treatments for aging populations

Abstract


Published online 09 February 2024

Efficient Removal of Acetamiprid Pesticide Using Date Core-Derived Activated Carbon and Korai Clay As A Good Sorbent

Huda Azhar Fadel 1*,  Lekaa Hussein Khdaim 1

Iraqi date core-derived activated carbon effectively removes acetamiprid pesticide, crucial for combating water pollution, supported by comprehensive adsorption studies.

Abstract


Published online 12 February 2024

A Double-blind, Randomized Clinical Trial Study of Plantago major l. Syrup on Menorrhagia

Sajedeh Ghasempour 1, Mohsen Naseri 2, Fatemeh Alijaniha 2, Yasin Karimi 3, Anoushirvan Kazemnejad 4, Shahrzad Hadavand 5 , Seyedeh Fatemeh Jafari 2, 6

The study highlights Plantago major's potential to reduce menorrhagia severity and duration, offering a promising complementary treatment with minimal side effects.

Abstract


Published online 13 February 2024

Understanding and Combatting COVID-19: Insights from Clinical Characteristics and Management Strategies

Bala Krishnan A 1, Vigneshwaran V 1, Tharani Kumar L 1, M. Shagar Banu 1

Timely analysis is crucial for understanding and combating global health crises like COVID-19 effectively

Abstract


Published online 13 February 2024

Concerning Fungal Coinfections in COVID-19: Risks, Types, and Prevention – A Review

Bala Krishnan A  1, Vinoth Kumar K K 1, Tharani Kumar L 1, M. Shajini G Inbakani 1

The review highlights the alarming rise of fungal infections like Mucormycosis among COVID-19 patients, necessitating prompt diagnosis and care to prevent fatalities.

Abstract


Published online 13 February 2024

Unprecedented Rise of Mucormycosis in COVID-19 Patients: Urgent Need for Protocol Adaptation and Awareness in India – A Review

Nithya A 1, Vinoth S V 1, Ashok Kumar M 1, Sindhu T 1

Mucormycosis in COVID-19 patients in India necessitates urgent updates in treatment protocols and public awareness

Abstract


Published online 14 February 2024

Navigating COVID-19 Treatment: CT Scans, Steroids, and Medical Practice Challenges in India

Jayanthi E 1, C. Elayaraja 2, Priyadharshini S 2, Ashok kumar M 2

The review highlights India's struggle with COVID-19, emphasizing the need for tailored treatments amid rising cases, cautioning against unnecessary tests and misuse of medications.

Abstract


Published online 14 February 2024

In vitro Cytotoxicity and Apoptotic Activity of Aquous, Chloroform and Methanol Extracts of Kiwi Fruit Actinidia deliciosa in MCF-7 cells

Kartheeswari 1, Archana C 1, Anupreyaa K 1, Saranya M 2

Assessment of A. deliciosa extracts' anticancer potential on MCF-7 cells offers insights for natural cancer medication development

Abstract


Published online 15 February 2024

Impact of Dapagliflozin on Atherosclerosis through Inflammation and Oxidative Pathways

Zainab Abdlkadhim Aboshnin 1*, Safa Azhar Razzaq 1, Zahraa Ibraheim Jawad Shubber 2

Atherosclerotic patients need therapies targeting inflammation and oxidation. This study supports Dapagliflozin's use for clinical benefits in atherosclerosis.

Abstract


Published online 15 February 2024

Association Between Low Bone Mineral Density in Hemophilia Patients and Musculoskeletal Function Impairments

Rasha Ibrahim Salman 1* , Khalid Mahdi Salih 1*, Nidal Karim Al-Rahal 2*

Hemophilia patients with low bone density (BMD) face higher risk with severe limitation of movement (LOM) and viral infections.

Abstract


Published online 16 February 2024

The Analysis of Hypertension Knowledge in Adults in Telafer City for Health Education and Intervention

 Mohammed Qassim Baktash 1* , Ali Ismael Sulaiman 1

Understanding hypertension in Telafer City adults is vital for preventing problems, guiding interventions, and managing the disease effectively

Abstract


Published online 17 February 2024

The Analysis of Hematological Parameters CBC, ABO, NLR, and APTT and Its Implications on Haemophilic Patients with Low Bone Mineral Density

Rasha Ibrahim Salman 1* , Khalid Mahdi Salih 1, Nidal Karim Al-Rahal 2

The study determined a high prevalence of low bone mineral density in hemophilic patients, associated with elevated NLR and prolonged APTT.

Abstract


Published online 17 February 2024

Efficacy of Paromomycin-Conjugated Nano Chitosan in Treating Entamoeba histolytica Infection in Mice

Hajar Falih Hishan Aldali 1*, Shatha Khudiar Abbas 1, Ahmed Naji Abd 1

Entamoeba histolytica causes widespread amebiasis. Chitosan-paromomycin nanoconjugates effectively treated infected mice, reducing liver enzyme levels, showing promising therapeutic potential.

Abstract


Published online 17 February 2024

Anti-Cancer Activity of Allium Ascalonicum Ethanol Extract Against Human Hepatocellular Carcinoma Cell Line (HepG-2)

Geetha N B 1*, Chintala Venkatesh 1, Suresh M 1, Manikandan S 2

Allium ascalonicum might be a safer, more effective alternative to toxic chemotherapy for combating cancer with targeted potency.

Abstract


Published online 18 February 2024

In vitro Anti-cancer Activity of Methanol Extracts of Kiwi Fruit, Actinidia deliciosa in HCT-119 Cells

Geetha N B 1, Priya R 1, Weslin D 1, Ashmi Christus A T 2

The study of anti-cancer properties of Actinidia deliciosa methanol extract in Colorectal cancer as effective treatments.

Abstract


Published online 18 February 2024

Green Fungus Challenges in Post-COVID Health Landscape

Jeha J 1, Sudha S 1, Geetha N B 1, Benitta Sherine S 2

This review provides Green Fungus challenge in post-COVID situation. Early detection, hygiene, and research are imperative.

Abstract


Published online 18 February 2024

Diagnosis of Chronic Brucellosis with Interferon-Gamma Quantification

Sarah Yahya Abdullah 1, Yasir Mufeed Abdulateef 2*, Sawsan Qahtan Taha Al-Quhli 3

This study showed the improvement of brucellosis diagnosis using interferon-gamma for better detection in chronic cases

Abstract


Published online 19 February 2024

Epidemiological Analysis of Hepatitis B and C Viruses in Fallujah for Health Intervention and Disease Control

Ahmed Saadi khlaf 1*, Asif Hasan Abdulrazaq 2, Nawar Bahaa Abdulsahib 3, Manaf Akram Ismaell 3, Mustafa Asif Hasan 3

Investigating Hepatitis B and C in Fallujah revealed higher prevalence among males, aiding targeted interventions and public health initiatives.

Abstract


Published online 19 February 2024

A study of Enhancing Fencing Skills with The Impact of Special Exercises on Kinetic Response and Attack Accuracy among Young Foil Players

Reem Mohammed Abdel Wahhab 1*

This study showed an improved exercise enhancing kinetic response, vital for fencing to optimize athletes' and their healthy performance.

Abstract


Published online 19 February 2024

Determination of Demographic Liver Health with Giardia lambila Infection Analysis in Diyala

Noora Dhyaaldain Abed 1*, Shahad Abdul Jabbar Mohammed 2*

This study analyzed the Giardia infection as early detection for liver health intervention.

Abstract


Published online 20 February 2024

Biofilms and Antibiotic Resistance Determination from Different Immunocompetent Patients with Salmonellosis

Mariam Ayad Abd 1*, Sawsan Q. T. Al-Quhli 2, Mahir Ali Jassim 3

This study discussed important information about antibiotic resistance and how harmful Salmonella bacteria are in Iraqi patients, helping to plan better public health measures.

Abstract


Published online 20 February 2024

Cumin Extract Alters The Histology of Kidney and Duodenum in Adult Rabbit

Hussein B. Mahmood 1*,  Naseer  A. Al-Arubaye 1, Walaa F. Obead 1

This study showed the histological alterations of the kidney and duodenum due to excessive use of cumin.

Abstract


Published online 22 February 2024

Factors Influencing Childhood Vaccine Refusal in Parents in Southern Malaysia and Its Effect on Health: A Cross-sectional Study

Sakina Ruhi 1*, Adlina Abdullatif 1, Jegathambigai R. Naidu 1, Hana Chen 1, Ayesha Syed 1, Danish Saud khan 2, Husni Ahmed Al Gosha 1, Sohayla Mohamed Elsherbini A 1, Mya Mya Thwin 1, Thin Thin Aung 1

This study sheds light on the important role that education and awareness play in overcoming vaccine hesitancy in Malaysia.

Abstract


Published online 24 February 2024

The Effect of Brain Natriuretic Peptide, and Prothrombin Biomarkers in Pregnant Women With Gestational And Chronic Hypertension

Saif al deen M. Khatlan 1*, Wijdan I.A. Abd-alwahab 2

A study of gestational hypertension (GH) and chronic hypertension (HT) impact pregnancy, emphasizing the importance of monitoring brain peptide and biomarkers.

Abstract


Published online 24 February 2024

Advancements of Polymer-Based Transdermal Drug Delivery Systems in Drug Bioavailability and Patient Compliance in United States

Hunny Dabas 1, Deepika Singh 1, Faraat Ali 2, Dipanjan Koley 1, Mohammed. Aslam 3, Esra Tariq Anwer Bayrakdar 3, Manvi Singh 1*

This review comprehensively discusses the transdermal drug delivery systems (TDDS) in the area of drug administration, for non-invasive, precise, and efficient delivery, overcoming oral limitations.

Abstract


Published online 25 February 2024

In vitro Cytotoxicity of Activated Carbon from Musa Acuminate Fruit Peel Against HepG-2 Cells

Shanmugasundaram M 1, Prasath S 2, Geetha N B 2, Manikandan S 2

Activated carbon from Musa Acuminate exhibits potent inhibitory effects on HepG-2 cells via ROS-mediated MTD pathway, suggesting therapeutic potential against cancer.

Abstract


Published online 26 February 2024

Spectrophotometric Determination of Vitamin C Using Indirect Oxidation with a New Organic Dye

Asmaa Ahmed Mohammed Alrashidy 1, Omar Adnan Hashem 1, Kalid Abdul-Aziz ALBadrany 1

The research focuses on the indirect determination of vitamin C in various pharmaceutical formulations, as well as in natural fruit samples and commercially available juices. For the first time, a novel organic dye was utilized in the process, and it was found that the method was indeed effective for the quantification of vitamin C in these products.

Abstract


Published online 27 February 2024

Interplay And Causative Relationship Between Frailty And Atherosclerosis

Anastasia V. Poznyak 1*, Victoria A. Khotina 2, Roghayyeh Vakili-Ghartavol 2,3, Victor Y Glanz 2, Vasily N. Sukhorukov 2, Alexander N. Orekhov 2*

Frailty syndrome (FS) and cardiovascular diseases have a significant interaction, which impacts both the patient experience and how they are managed. Knowledge about the intricate associations between the two could provide a meaningful way towards developing targeted interventions.

Abstract


Published online 27 February 2024

Neoatherosclerosis And Paleoatherosclerosis: Complications After Stenting

Anastasia V. Poznyak 1*, Victoria A. Khotina 2, Roghayyeh Vakili-Ghartavol 2,3, Victor Y Glanz 2, Vasily N. Sukhorukov 2, and Alexander N. Orekhov 2*

Enhanced imaging techniques help in the comprehension of neoatherosclerosis and paleoatherosclerosis, which are crucial for preventing stent failure and improving treatment approaches.

Abstract


Published online 28 February 2024

A Post-Pandemic Insight on The Covid-19 and Pregnancy in Malaysia

Hana W. Jun Chen 1,*, Jegathambigai Rameshwar Naidu 1,*, Mohamed Najimudeen 1, Sakina Ruhi 1, Roy Rillera Marzo 2, Abdulah Y. Al-Mahdi 1, Haryati Anuar 1, Mohammed Faez Baobaid 1, Fatmawati Syamsu 3, Mohammed A. Abdalqader 4

In the midst of the Omicron surge, Malaysia is adjusting its approach, highlighting the importance of vaccination, updated guidelines, and community engagement as crucial means to mitigate the impact of COVID-19.

Abstract


Published online 28 February 2024

Positive Coping and Community Resilience in Disaster Management for Flooding in Malaysia

Hana W. Jun Chen 1,*, Roy Rillera Marzo 2, Mila Nu Nu Htay 3, Sakina Ruhi 1,*, Sarah Mohd Zainal Abidin 1, Allistair Adam Nelson 1, Haryati Anuar 1, Jegathambigai Rameshwar Naidu 1, Irma Muslimin 4, Andi Salim 5

Recognizing the significance of coping mechanisms in fostering community resilience is essential for reducing the effects of flooding and enhancing health risks and disaster preparedness in Malaysia.

Abstract


Published online 28 February 2024

Review on Angiogenesis Modulation by Natural Compounds as Therapeutic Potential and Mechanisms

Jegathambigai Rameshwar Naidu 1* , Sasidharan Sreenivasan 2, Sakina Ruhi 1, Hana W. Jun Chen 1, Sanjith Rameshwar Naidu 1, Danish Khan 3, Thin Thin Aung 1, Mya Mya Thwin 1, Husni Ahmed Al-Goshae 1, Subramanian Rammohan 1

Compounds derived from plants that have antiangiogenic effects could be used in the development of drugs that target this stage of angiogenesis.

Abstract


Published online 28 February 2024

Determination of Vitamin K2, Lipoprotein (a) and N-Terminal pro Brain Natriuretic Biomarkers in Diabetic Hypertensive Patients with Acute Myocardial Infarction for Clinical Intervention

Ghaith Kamil Jawad 1*, Abdulsamie Hassan Alta'ee 2 , Oday Jasim Alsalihi 3

This study showed the biomarkers like NT-proBNP, Lp(a), and vitamin K2 might be valuable for AMI prognosis, aiding risk stratification and therapeutic decisions.

Abstract


Published online 03 March 2024

Enhancing Breast Cancer Classification: A Deep Learning Approach with Outlier Detection With Egret Swarm Optimization Algorithm and Feature Selection Integration – A Systematic Review

S. Maria  Sylviaa 1*, N. Sudha 1

Early Breast Cancer diagnosis via data mining is crucial. Proposed methods achieve high accuracy, improving treatment outcomes for patients significantly.

Abstract


Published online 28 February 2024

Vitamin D In Modulating Liver And Kidney Functions Following Cadmium Exposure In Vivo

Walid Theib Mohammad 1*, Ahmad Maher AL Sayeh 1, Fernando Jesús Plaza del Pino 2

The research determined how vitamin D plays a vital part in relieving kidney and liver damage from cadmium, thus having important implications for treatment.

Abstract


Published online 03 March 2024

Wild Horse Optimizer and Support Vector Machine (SVM) Classifier Predicts The Heart Disease Converging Nature-Motivated Optimization and Machine Learning

Vishwanadham Mandala 1*, Srinivas Naveen Dolu Surabhi 2, V. R. Balaji 3, Dipak Raghunath Patil 4, Saiyed Faiayaz Waris 5, G. Shobana 6

Heart disease, responsible for millions of deaths annually, necessitates early detection. Machine Learning offers efficient, cost-effective diagnostic tools. The proposed Wild Horse Optimizer (WHO) and SVM classifier enhance heart disease forecasting, addressing critical healthcare needs.

Abstract


Published online 04 March 2024

A Novel Framework of Hybrid Optimization Techniques for Contrast-Enhancement in Cardiac MRI Medical Images

Radhika R. 1*, Rashima Mahajan 1

Enhancing medical image contrast improves diagnosis accuracy. COA-SCSO optimizes parameters efficiently, ensuring clearer images and better patient care outcomes.

Abstract


Published online 04 March 2024

Integrated Approach for ECG Signal Classification Using Fused Slantlet Transform and Autoregressive Features

 ALI Aalsaud 1*, Raghad Z. Yousif 2, 3

The novel ECG analysis method improves detection accuracy, is vital for early diagnosis of CVD, and potentially saves lives, especially in underserved regions.

Abstract


Published online 04 March 2024

Modified VGG-19 Deep Learning Strategies for Parkinson's Disease Diagnosis - A Comprehensive Review and Novel Approach

Aruna Kokkula 1*, P. Chandra Sekhar 2, T. M. Praneeth Naidu 3

This review describes the upgraded ability to diagnose PD through deep learning and an altered VGG19 model, offering an accuracy rate of nearly 98%, reshaping the neurology treatment field.

Abstract


Published online 05 March 2024

Synthesis, characterization and Antibacterial Evaluation of Novel Thiazolidine Derivatives

Shaima H. Abdullah 1*, Mahmoud M. Salih 1, Khalid, A. Al-Badrany 1*

Thiazolidine derivatives, synthesized from heterocyclic compounds, exhibit diverse biological activities, including antibacterial effects against various bacterial strains, suggesting potential pharmaceutical applications.

Abstract


Published online 05 March 2024

Synthesis, characterization and Antibacterial Evaluation of Novel 1,3-Oxazepine Derivatives Using A Cycloaddition Approach

Farah M. Muhammad 1*, Bushra A. Khairallah 1*, K. A. Albadrany 1*

This study demonstrated a novel approach to the synthesis of oxazepine derivatives, key heterocyclic compounds with potential pharmacological applications.

Abstract


Published online 06 March 2024

Determination of Health Service for Beneficiary Satisfaction: A Study of Maysan Child and Maternity Hospital

Saad Bader Abbas 1*, Rihab Al-Bedoui Bin Salem 2*

Research on health service satisfaction highlights vital insights for improving care, enhancing patient well-being, and optimizing resource utilization for better outcomes.

Abstract


Published online 06 March 2024

Prolonged Formalin Exposure on Liver and Kidney Function Associated with TP53 Gene Expression in Quail Birds (Coturnix coturnix)

Iman Ibrahim Al hacham 1, Abdulrazzaq B. kadhim 2*, Eman F. Albaghdady 3

This study demonstrated a prolonged formaldehyde exposure in quails. It caused liver and kidney damage and affected gene expression as potential cancer risks.

Abstract


Published online 06 March 2024

An intra-oral infection Halitosis and its Causes, Diagnosis, and Treatment Strategies – A Systematic Review

Noora Abdulrazzaq Naji 1*, Safa Ali Hamad 2, Samar Khalid Al-Adel 2, Hamsa Thabet Musa 2, Saja Sami Malik 2 

Halitosis, a prevalent issue, often remains untreated, causing social discomfort. Oral causes, especially bacterial buildup, necessitate effective dental management strategies.

Abstract


Published online 07 March 2024

Healthcare Monitoring-based IoT framework for heart disease detection and classification

J. Shafiq Mansoor 1, Kamalraj Subramaniam 2

The review discused the Healthcare Monitoring based IoT framework (HM-IoT) and determined the security rate and classification accuracy.

Abstract


Published online 07 March 2024

Advances in Periodontal Drug Delivery Systems and the Role of Probiotics in Periodontitis Treatment

Pratikshya Mohanty 1, Kalpita Bhatta 1*, Itishree Jogamaya Das 2,  Himansu Bhusan Samal 3*

This review discussed the periodontitis and its prevalence in gum inflammation and bone loss. Local drug delivery systems offer effective treatment, enhancing patient care.

Abstract


Published online 07 March 2024

Immunological Significance of Meconium-Stained Amniotic Fluid with Complement Factors C3 and CD4 Levels for Pregnancy Health

Hanan Fawzi  Salman 1, Imtithal I. J. 1, Nagam Khudhair 1*

This research demonstrated the immune factors C3 and CD4 activity in amniotic fluid on prenatal health, which can diagnose the meconium-stained liquor complications early.

Abstract


Published online 07 March 2024

Simulation and Modeling of Water Treatment Plant with GPS-X Software for Health and Water Quality

Nabaa Abdul- Kareem 1*, Jabbar H. Al-Baidhani 1

This research determined the quality of the Water Treatment Plant using special software that verified the function of water treatment plants to ensure health safety.

Abstract


Published online 08 March 2024

Morphometric Study of Epicardium and Myocardium Thickness in Adult Human Hearts

Noor Abbas Ramadan 1*, Elham Majeed Mahmood 1, Saad Ahmed Mohammed 1

This study demonstrated the heart layer morphology, providing insights into cardiac anatomy, age, and gender influences, aiding clinical diagnosis and treatment.

Abstract


Published online 08 March 2024

Inflammatory Modulation of Interleukin-17 and -23 in Long COVID Diabetic Patients

Esra Hassan Abd Ali 1*

The global COVID-19 pandemic disrupted daily life. This study demonstrated Long COVID's severity, especially in diabetic individuals, highlighting inflammation's crucial role.

Abstract


Published online 08 March 2024

Postmenopausal Hormone, Hematology and Immune Modulation in Rheumatoid Arthritis Patients

Luma Qasim Ali 1, Firas Salih Abdulhadi 1, Ban Talib El-Haboby 1, Jamela Jouda 1*

This research determined the significant hematological, hormonal, and immunological changes in postmenopausal women with RA or SLE in compared to controls. This investigation had a high potential for therapeutic intervention.

Abstract


Published online 08 March 2024

Novel Cardiac Biomarkers H-FABP and GPBB for Early Detection and Prognosis of Acute Myocardial Infarction

Hayder T Qaddoori 1*, Fatima Mallalah Mohammed 2, Ali Najm Abdullah 1

Novel cardiac biomarkers H-FABP and GPBB might improve the early diagnosis for myocardial infarction detection (within 1-4 hours of chest pain). H-FABP and GPBB proteins were investigated for identifying the heart muscle problems in this study.

Abstract


Published online 29 February 2024

Genetic Variants of CYP2C8 Gene Predisposition to Type 2 Diabetes Risk

Saleh Abd-Qader Abed 1, Ammar Ahmed Sultan 1*

This study determined the genetic variations in the CYP2C8 gene which may illuminate predispositions to type 2 diabetes.

Abstract


Published online 29 February 2024

Treatment of Hypothyroidism with Flavonoid Rich Extract of Fucus vesiculosus L Algae in Adult Rats

Somaya M. Eshtiwi 1*

Flavonoid extract from Fucus vesiculosus algae showed a thyroid activity modulator for the treatment of thyroid disorders.

Abstract


Published online 08 March 2024

Elytrigia Repens Extracts Control Urban Mosquito Vectors with a Larvicidal Potential

Prakash D 1*, Mohideen Abdulkader M 1, Sakthivel D 1, Manju I 1, Sreenivasan K S 1, Manikandan S 2

This study demonstrated larvicidal activity to prevent mosquito disease and its spread, which might be due to insecticidal phytocompounds in the extract.

Abstract


Published online 29 February 2024

A Retrospective Study of Outbreak and Vaccination on Measles Inflammation

Hayder Sudan Abbas Obaid 1, Ali Jaafar Mohammed 1, Laith A.I.K. Al-Kaif 2, *, Doaa Adil Abood 3, Younis A.K. Al-Khafaji 4

Understanding risk factors, vaccination rates, and surveillance effectiveness is crucial for developing targeted strategies to prevent measles infections in Iraq.

Abstract


Published online 09 March 2024

Risks, Identification, and Antibiotic Susceptibility Against High Prevalence of Bacterial Infection in Contact Lens Solutions

Rana S. Hasan 1,  Sawsan M. Alomari 2, Roaa A. Thamer 3, Mohammed Fadhil Haddad 4*

This study determiend the microbial contamination in contact lens solutions for preventing eye infections and improving lens safety practices.

Abstract


Published online 09 March 2024

A Rapid Continuous Flow Injection Analysis Method Development for Diphenhydramine Hydrochloride

Asma A. Gayed Al-Ani 1* , Nagham S. Turkey Al-Awadie 1*

Novel flow injection analysis improves Diphenhydramine HCL detection in pharmaceuticals with high sensitivity, speed, simplicity, and cost-effectiveness, enhancing industrial efficiency.

Abstract


Published online 10 March 2024

Advances in Peer Teaching Methods in the Skill and Physical Development

Sura Gasid Hasan 1*

The study showed an innovative education for modern needs, improving basketball skills via peer teaching. Diverse methods motivate learners, enhancing health outcomes.

Abstract


Published online 10 March 2024

Heavy Metal Accumulation and Phytochemical Profiling of Brassicaceae and Amaranthaceae for Phytoremediation and Medicinal Applications

Abdulilah Hanan Abdul Qader 1, Hind Hamid Hasan 2, Ashwaq Talib Hameed 3*, Hanan Y. Houmady 4, Rafraf abdul aziz abdul qader 5

The study provides valuable insights into heavy metal absorption by specific Iraqi wild plants, offering opportunities for phytoremediation and medicinal applications.

Abstract


Published online 10 March 2024

Synthesis, Charecterization, Antibacterial and Cytotoxicity of Novel Metal Complexes Derived from Azomethine Ligand (Bis Azo-Schiff Base) In Vitro and In Silico

Hussein Abdulkadhim Hasan 1*, Saad M. Mahdi 1, Hanaa Addai Ali 2

This study demonstrated the synthesis of Schiff bases, like azo-Schiff metal complexes, showing therapeutic effects.

Abstract


Published online 11 March 2024

High Fibroblast Growth Factor 23, Sialic Acids, and Albumin Modulation in Alzheimer’s Patients

Hashim Abdul-Sattar J. Al-Bajalani 1*

This study demonstrated a potential biomarkers and mechanisms underlying AD pathology for novel therapeutic strategies in future. Understanding serum biomarkers and oxidative stress in Alzheimer's disease (AD) is crucial for early diagnosis and targeted interventions.

Abstract


Published online 11 March 2024

High HbA1C and Glycemic Control as Diabetic Nephropathy Etiology

Iman Kamel Aati 1*, Hawrra Jabbar Mohammed 2, Muhanad Mahdi Mohammed 3, Raya Najim Rasool Altimimy 4

High HbA1c levels correlate with diabetic nephropathy severity, urging comprehensive glycemic control for mitigating complications and improving diabetic outcomes.

Abstract


Published online 11 March 2024

Control Mycotoxin Contamination in Tarasas Food Using A Lab Fermantion

Baraa Jameel Al-Assil 1,2*, Taghreed Abed Wahwah 3 

By utilizing LAB-mediated fermentation, this study demonstrated a natural and effective method for controlling mycotoxin contamination in traditional Tarasas food.

Abstract


Published online 12 March 2024

Advances in Diagnosis and Treatment of Fabry Disease: A Review of Clinical Manifestations and Therapeutic Interventions

Mikhail A. Popov 1, Anastasia V. Poznyak 2*, Vladislav V. Dontsov 1, Julia Y. Kotalevskaya 1, Alexey B. Zulkarnaev 1, Vadim S. Tsy-plakov 1, Margarita A. Sazonova 3, Marina D. Sazonova 3, Elizaveta M. Pleshko 4, Victor Y Glanz 4, Vasily N. Sukhorukov 4, and Al-exander N. Orekhov 4*

This review discussed a treatment algorithm for advancing medicine, and patient outcomes of Fabry disease.

Abstract


Published online 13 March 2024

The Role of Natural Compounds for Atherosclerosis Treatment: Lessons Learned from The Use of Curcumin

Anastasia V. Poznyak 1*, Victoria A. Khotina 2, Roghayyeh Vakili-Ghartavol 3, Victor Y Glanz 2, Vasily N. Sukhorukov 2, and Alexander N. Orekhov 2*

Curcumin has various pharmacological effects on atherosclerosis. This review discussed the promising therapeutic potential, of curcumin as anti-inflammatory, lipid regulation, and endothelial function for cardiovascular disease.

Abstract


Published online 14 March 2024

Exploring the Link between Chronic Inflammation and Atherosclerosis-Endometriosis Association

Anastasia V. Poznyak 1,*, Vasily N. Sukhorukov 2, Igor A. Sobenin 2, Vladimir P Ofitserov 3, Anton Y. Postnov 2, Alexander N. Orekhov 2,*

Understanding shared inflammation mechanisms in atherosclerosis and endometriosis informs innovative interdisciplinary treatments, enhancing patient care and outcomes comprehensively.

Abstract


Published online 15 March 2024

Advances in Cellular Models of Atherosclerosis

Anastasia V. Poznyak 1*, Victoria A. Khotina 2, Victor Y Glanz 2, Vasily N. Sukhorukov 1, Igor Alexandrovich Sobenin 2, and Alexander N. Orekhov 1

Atherosclerosis models, from 2D cultures to 3D tissue-engineered vessels, offer cost-effective avenues for drug screening and personalized medicine, advancing therapeutic discovery.

Abstract


Published online 19 March 2024

A Study of Biochemical Markers in Uterine Cancer Diagnosis with Radiotherpay Treatment In Iraq

Wael Sahib Alnweny 1*, Mohammed Q. Almayali 1*, Mohammed A. Dakhil 2, Hiba Ali Numan 1, Yasir J. Abbas 3

Effect and investigation of radiotherapy of clinical biomarkers in Uterine Cancer patients.

Abstract


Published online 20 March 2024

Study of Antibiotic Resistance in ESKAPE Bacteria Using β-lactamase and ESBL Genes

Hiba Ahmed Jawade 1*, Zahraa Yosif Motaweq 2, Hawraa Dheyaa Rasool 3,  Fatima Hassan Hussain 1

This study determined the resistance mechanisms of SKAPE group bacteria. Understanding this bacterial resistance mechanisms, particularly β-lactamase production, is crucial for effective treatment and infection control.

Abstract


Published online 22 March 2024

High Growth Differentiation Factor-15 (GDF-15) in Rheumatoid Arthritis Patients Potential Risk for Cardiovascular Disease

Ghufran Abd Omran Abdulridha 1,2*, Mustafa Abdulkadhim Hussein 3, Suhad Rasheed Majeed 3

 

This study showed the high levels GDF-15, a clinical marker in rheumatoid arthritis, signified disease progression and heightened cardiovascular risk, implicating inflammation and tissue damage.

Abstract


Published online 23 March 2024

Nanoparticle-Mediated Plasmid Curing in Combating Antibiotic Resistance in Pathogenic Bacteria

Muntaha R. Ibraheem 1*, Dhafar N. Al-Ugaili 2

Novel approach fights antibiotic resistance. Enhances DNA extraction efficiency. Eliminates resistance plasmids, aiding biotechnology. Highlights research needs for nanoparticle optimization and mechanism understanding.

Abstract


Published online 25 March 2024

Nutritional Evaluation of Cassava Meal Components and Maize in Securing Feed and Food

Shahabuddin Ahmed 1,2, Mrityunjoy Biswas 2*, Atiqur Rahman Sunny 3, Farhana Irin 4, Md Faruk Hossain 5, Md Mostafizur Rahman 5, Md Abu Bakar Siddique 5, Md. Alauddin 6, Mrinal Kanti Debnath 2, Md. Pallo Hossain 2, Tufael 3, 7

This study assesses the nutritional composition of cassava and maize, pivotal crops for food and animal feed production globally, offering insights into dietary recommendations, agricultural practices, and food security measures in regions reliant on these staples.

Abstract


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