Disrupting Bacterial Biofilms to Combat Dental Diseases Using Nanotechnology in Oral Healthcare

Hunny Dabas¹, Faraat Ali^2, Fairy³, Khushi Quadri¹, Manshi Dangi¹, Parween Jamil⁴, Mohammed Aslam⁵, Manvi Singh¹*

This review discusses the use of nanoparticles as innovative solutions for disrupting bacterial oral biofilms, enhancing antimicrobial efficacy, and revolutionizing oral healthcare with minimal resistance.

Abstract

Oral biofilms, predominantly bacterial, are key contributors to dental caries and periodontal diseases, posing significant challenges to oral health management. Conventional methods, including mechanical removal and antimicrobial agents, often prove inadequate due to the inherent resilience and complexity of biofilm structures. Recent advancements in nanotechnology offer a transformative approach to biofilm disruption, presenting unique opportunities for oral healthcare innovation. Nanoparticles, with their distinct physicochemical properties, enable precise interactions with bacterial cells and effective penetration into biofilms, targeting bacteria in otherwise inaccessible areas. Their multifunctional nature facilitates the delivery of combined therapeutic agents, enhancing antimicrobial efficacy and addressing diverse bacterial strains. These properties underscore the potential of nanoparticles to overcome the limitations of traditional treatments, paving the way for targeted, efficient, and minimally invasive strategies. As research evolves, the integration of nanoparticles into oral healthcare practices promises to revolutionize the management of bacterial biofilms, offering personalized and groundbreaking solutions to improve oral health outcomes.

Keywords: Chronic Dental Infections, Nanotechnology, Nanoparticles, Oral Biofilms and Dental Biofilms.

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