Integrative Biomedical Research (Journal of Angiotherapy) | Online ISSN  3068-6326

Integrative Biomedical Research

Integrative Biomedical Research is an, international, peer-reviewed, Open Access journal that publishes research articles on all aspects of biomedical, medicine, public health, 

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Editor-in-Chief: Fazlul Huq, Ph.D.

Integrative Biomedical Research

Volume 9 Number 1 2025

Table of Contents


Research Article

Drug Delivery

Published online 23 December 2024

In Silico Determination of Tinospora cordifolia Phytochemicals as Potential DPP-4 Inhibitors for Type 2 Diabetes Management

Ebenezer A. Oni1*, Temitope Ogunmola2, Aminat A. Alowonle3, Damilola A. Omoboyowa1

pp. 1-8

This study determined Tinospora cordifolia phytochemicals as potential DPP-4 inhibitors, offering promising therapeutic candidates for type 2 diabetes.

Abstract | Full Text |PDF (870 KB) | Open Access Article


Published online 11 September 2024

Addressing Cardiovascular Disease Disparities Among Medicare Beneficiaries: Insights from the Indian Health Service

Birendra Kumar Sahu 1*, Kishor Kumar Sahu 1

pp. 1-6

This research demonstrates urgent disparities in cardiovascular health among Medicare beneficiaries, emphasizing the need for targeted interventions in vulnerable communities.

Abstract | Full Text |PDF (186 KB) | Open Access Article


Published online 10 September 2024

Impact of Multi-Component Outreach on Colorectal Cancer Screening and Genetic Testing Preferences

Sanjay Kumar Mire 1*, Varri Srinivasa Rao 1

pp. 1-7

This study elucidates the critical role of outreach strategies in increasing colorectal cancer screening and genetic testing participation.

Abstract | Full Text |PDF (352 KB) | Open Access Article


Published online 10 September 2024

Impact of Pharmacist-Led Interventions on Hypertension Management in Cancer Patients Undergoing Chemotherapy

Prachi Gurudiwan 1*, Ritesh Patel 1

pp. 1-7

This study determines the pharmacists' essential role in managing hypertension, enhancing cancer patient care, and improving overall health outcomes through targeted interventions.

Abstract | Full Text |PDF (405 KB) | Open Access Article


Published online 10 September 2024

Milk-Based Ointment Accelerates Wound Healing: A Comparative Study in Rabbits

Chiranjeev Singh 1*, Kunal Chandrakar 1

pp. 1-7

This study demonstrated that a 5% milk-based ointment significantly accelerated wound healing and improved tissue strength compared to conventional treatments in rabbits.

Abstract | Full Text |PDF (530 KB) | Open Access Article


Published online 10 September 2024

The Impact of Clinical Pharmacists on Cardiovascular Disease Management in Spain: A Community Pharmacy-Based Intervention Study

Deepak Kumar Sahu 1*, Himanshu Nirmal Chandu 1

pp. 1-7

This study determined the critical role of clinical pharmacists in reducing cardiovascular disease risk factors, improving patient outcomes through community-based interventions.

Abstract | Full Text |PDF (475 KB) | Open Access Article


Published online 09 September 2024

ATC-CNN-Based IoT Framework for Real-Time Cardiovascular Monitoring: A Comparative Analysis with Deep Learning Models

Dev Ras Pandey 1*, Ahilya Dubey 1

pp. 1-6

This study determines the ATC-CNN’s superior performance in real-time monitoring of cardiovascular patients revolutionizes care, enhancing access, accuracy, and clinical outcomes.

Abstract | Full Text |PDF (552 KB) | Open Access Article


Published online 09 September 2024

Effects of Low-Dose X-Ray Exposure on Hematological Parameters In Vivo

Venu Anand Das Vaishnav 1*, Syed Sabir Ali 1

pp. 1-5

This study determined the risks of low-dose X-ray exposure on blood parameters, contributing to radiation safety knowledge.

Abstract | Full Text |PDF (207 KB) | Open Access Article


Published online 09 September 2024

Shatadhauta Ghrita and Panchavalkala Prevent Wound Healing In Vivo

Tripti Dewangan 1*, Kishor Kumar Sahu 1

pp. 1-5

This study determined the potential of ancient Ayurvedic formulations for modern wound care, promoting effective healing while reducing treatment costs.

Abstract | Full Text |PDF (264 KB) | Open Access Article


Published online 08 September 2024

Enhancing Ovarian Cancer Detection Using Self-Organizing Maps and Improved Recurrent Neural Networks with Extended Harmony Search Optimization

Priya Vij 1*, Patil Manisha Prashant 1

pp. 1-5

This study determined a novel approach combining SOM and IRNN with EHSO to enhance early detection of ovarian cancer, improving diagnostic accuracy and efficiency.

Abstract | Full Text |PDF (574 KB) | Open Access Article


Published online 08 September 2024

Predicting Cardiovascular Disease Risk Using Web-Text Sentiment Analysis and Hybrid Deep Learning Models

Abhijeet Madhukar Haval 1*, Md Afzal 1

pp. 1-5

This study demonstrated the superior potential of Web-Text Sentiment Analysis in predicting cardiovascular disease over demographic-based models.

Abstract | Full Text |PDF (427 KB) | Open Access Article


Published online 07 September 2024

A Nesting Segmenting and Categorizing Model for Diabetic Wound Depth Detection in Foot Using Convolutional Neural Networks

Omprakash Dewangan 1*, Ankita Tiwari 1

pp. 1-5

This research demonstrates a novel Mask R-CNN with ResNet-FPN framework for improved segmentation and classification of Diabetic Foot Ulcers, enhancing diagnostic accuracy.

Abstract | Full Text |PDF (225 KB) | Open Access Article


Published online 06 September 2024

Augmented Reality-Based Chronic Wound Healing Assessment Using 3D Stereoscopic Imaging and Self-Organizing Maps

Bhuneshwari Dewangan 1*, Mahendra Kumar Sahu 1

pp. 1-7

This study presents a novel AR-based approach for accurate, non-invasive chronic wound evaluation, enhancing clinician-patient communication and care.

Abstract | Full Text |PDF (461 KB) | Open Access Article


Published online 05 September 2024

Enhancing Radiological Biomedical Natural Language Processing Tasks with Radiology-Specific Word Encodings: A Comparative Analysis of Word Embeddings Sources

Kamlesh Kumar Yadav 1*, Dhablia Dharmesh Kirit 1

pp. 1-6

This study demonstrates Radiology-specific word encodings potential in improving the performance of radiology-focused BNLP tasks using diverse word embeddings.

Abstract | Full Text |PDF (536 KB) | Open Access Article


Published online 04 September 2024

Enhancing Pharmaceutical Supply Chains through Blockchain Technology on Hyperledger Fabric Implementation

Poorti Sharma 1*, Syed Sajid Ali Syed Sabir Ali 1

pp. 1-7

Digitizing supply chains with Blockchain technology improves transparency, reduces costs, and ensures secure medication distribution, crucial for pharmaceutical safety.

Abstract | Full Text |PDF (844 KB) | Open Access Article


Published online 03 September 2024

Advancing Heart Disease Forecasting: Integrating CNN-LSTM Models with Feature Enhancement for Improved Predictive Accuracy

Nidhi Mishra 1*, Ghorpade Bipin Shivaji 1

pp. 1-6

Combining CNN and LSTM models with feature enhancement significantly improves heart disease prediction, offering precise and timely interventions.

Abstract | Full Text |PDF (373 KB) | Open Access Article


Published online 02 September 2024

Enhancing Medication Safety with ML-Enhanced Decision Support Systems: A Comparative Analysis of Prescription Error Detection

F Rahman 1*, Lalnunthari 1

pp. 1-6

This study demonstrates that integrating machine learning with decision support systems significantly improves prescription error detection, reducing medication errors and enhancing patient safety.

Abstract | Full Text |PDF (241 KB) | Open Access Article


Published online 01 September 2024

Enhanced ResNet50 Model for Aqueous Solubility Prediction of Drug Compounds Using Deep Learning Techniques

Omprakash Dewangan 1*, Vasani Vaibhav Prakash 1

pp. 1-6

This study presents a novel 20-layer ResNet50 model for improving drug solubility predictions, surpassing traditional methods and human expertise.

Abstract | Full Text |PDF (293 KB) | Open Access Article


Published online 13 August 2024

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Quantification of Glycyrrhizic Acid in FLEGMEN-SIP Capsules Using High-Performance Liquid Chromatography for CNS Disorders

Matazimov M.T. 1*, Sidametova Z.E. 1, Olimov N.K. 1, Abdullaeva M.U. 1, Rakhimova D.O. 1, Rustamov I. X. 1, Umurzakova N.S. 1

pp. 1-5

This study validates HPLC for accurately quantifying glycyrrhizic acid in FLEGMEN-SIP capsules, ensuring therapeutic compliance for neurological treatments.

Abstract | Full Text |PDF (376 KB) | Open Access Article


Published online 28 July 2024

Lanctos 75™ is A Novel Retino-Protective and Neovascular Inhibitor for Diabetic Retinopathy

Fouad Saleih Resq Al-Suede 1, Muhammad Asyraf Abduraman 1, Indumathi Ashok 2, Gnanasekaran Ashok 3, Khadeer Ahamed basheer 1, Amin Malik Shah Abdul Majid 4,5*, Aman Shah Abdul Majid 2*

pp. 1-9

This study evaluates Lanctos 75™ as a potential therapeutic agent for diabetic retinopathy, targeting angiogenesis, oxidative stress, and inflammation.

Abstract | Full Text |PDF (727 KB) | Open Access Article


Published online 14 July 2024

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ANK-1, ANK-2, ITL-2 Polyphenols in a Dexamethasone-Induced Rat Model of Type 2 Diabetes Mellitus Treatment

Raimova Guli Madmurodovna1, Nasirov Kabil Erkinovich1, Khodjiyev Sirojiddin Salimovich.1,Ortikov Mukhamadkodir Musajonovich1, Maxmudov Rustam Rasuljonovich2, Toshtemirova Muazzam Akmaljonovna3, Isagalieva Sadafhon Mukhammadaminovna3 ,Usmanova Muhayyokhan Sobirjonovna4

pp. 1-11

This study demonstrated the potential of specific polyphenolic compounds in regulating hemostasis and biochemical imbalances in type 2 diabetes mellitus.

Abstract | Full Text |PDF (384 KB) | Open Access Article


Published online 06 June 2024

Cone Beam CT to Map Mandibular Foramen Variations for Improving Dental and Surgical Accuracy

Ryaheen Ghazi Rashid 1*, Rand Mohammed Abdul-Jabbar 1, Wedyan Yaseen 1, Suha Khaleel Ibrahim 1

pp. 1-8

This study enhanced precision in dental and surgical procedures by detailing mandibular foramen variations influenced by gender and age, reducing complications.

Abstract | Full Text |PDF (379 KB) | Open Access Article


Published online 15 February 2024

Impact of Dapagliflozin on Atherosclerosis through Inflammation and Oxidative Pathways

Zainab Abdlkadhim Aboshnin 1*, Safa Azhar Razzaq 1, Zahraa Ibraheim Jawad Shubber 2

pp. 1-7

Atherosclerotic patients need therapies targeting inflammation and oxidation. This study supports Dapagliflozin's use for clinical benefits in atherosclerosis.

Abstract | Full Text |PDF (360 KB) | Open Access Article


Reviews

Drug Delivery

Published online 02 May 2025

Advanced Dissolution Testing for Novel Drug Formulations: Challenges, Emerging Methods, and Regulatory Perspectives

Mohammad Lutfor Rahman1*, Md Al Mamun2, Ahad Ahamed3, Mohosin Kabir4, Faranak Nadarkhani Dinehkaboudi4, Marziyeh Zangeneh4, Md. Nezab Uddin5, AHM Quamruzzaman6

pp. 1-16

This study enhances drug release evaluation and improves therapeutic outcomes using advanced dissolution testing techniques.

Abstract | Full Text |PDF (565 KB) | Open Access Article


Published online 07 January 2025

PEGylated Liposomal Teriflunomide: A Novel Approach of Targeted Breast Cancer Treatment to Advance Efficacy and Minimize Adverse Effects

Dipanjan Koley1, Vaibhav Walia2, Mohammed. Aslam3, Manvi Singh4*

pp. 1-18

Developing pegylated liposomal teriflunomide may enhance breast cancer treatment efficacy, reduce side effects, and improve patient outcomes.

Abstract | Full Text |PDF (426 KB) | Open Access Article


Published online 01 November 2024

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Disrupting Bacterial Biofilms to Combat Dental Diseases Using Nanotechnology in Oral Healthcare

Hunny Dabas1, Faraat Ali2, Fairy3, Khushi Quadri1, Manshi Dangi1, Parween Jamil4, Mohammed Aslam5, Manvi Singh1*

pp. 1-14

This review discusses the use of nanoparticles as innovative solutions for disrupting bacterial oral biofilms, enhancing antimicrobial efficacy, and revolutionizing oral healthcare with minimal resistance.

Abstract | Full Text |PDF (673 KB) | Open Access Article


Published online 11 September 2024

Real-World Insights into CAR T-Cell Therapy: Efficacy and Safety of Kymriah in B-ALL and NHL

Harish Jaiswal 1*, Aayush Vaishnaw 1

pp. 1-7

This study provides extensive real-world data on Kymriah's efficacy and safety, revealing valuable insights into its use in B-ALL and NHL.

Abstract | Full Text |PDF (729 KB) | Open Access Article


Published online 09 September 2024

A Review of Radiology and Optical Coherence Tomography in Dental Diagnostics

Hemlata Dewangan 1*, Mahendra Kumar Sahu 1

pp. 1-5

This review assessed the advantages, limitations, and combined efficacy of radiology and OCT in dental diagnostics, enhancing imaging precision.

Abstract | Full Text |PDF (548 KB) | Open Access Article


Published online 09 August 2024

Artificial Intelligence in Drug Development and Delivery: Opportunities, Challenges, and Future Directions

Rabi Sankar Mondal1*, Lamia Akter2, Md Nazmul Alam Bhuiyan1

pp. 1-10

AI is revolutionizing drug development by accelerating discoveries and creating more personalized treatments, thereby making healthcare more efficient for everyone.

Abstract | Full Text |PDF (335 KB) | Open Access Article


Published online 22 January 2024

Machine Learning-Based Enhanced Drug Delivery System and Its Applications – A Systematic Review

Abhijeet  Madhukar Haval 1*, Kumar Shwetabh 1, Sushree Sasmita Dash 1

pp. 1-9

Machine Learning (ML) transforms drug development, predicting drug properties, targets, interactions, and facilitating efficient exploration for researchers and pharmaceutical companies.

Abstract | Full Text |PDF (528 KB) | Open Access Article


Published online 02 July 2022

Therapeutic Targeting on Death Pathways in Glioblastoma

Pavithra Suppiah1, Julia Joseph1, Rolla Al-Shalabi1, Nik Nur Syazni Nik Mohamed kamal1, Nozlena Abdul Samad1*

pp. 637-645

Abstract | Full Text |PDF (311 KB) | Open Access Article


Published online 18 December 2021

Clinical Implications and Diagnostic Methods of Microalbuminuria: Early Detection and Management Strategies

Jayamathi Govindaraj1*, Keerthidaa Govindaraj2, S.Bhuminathan 3, Kesavaram Padmavathy4 Vidyarekha U5, Kannan N6, Yogarajan R6

pp. 1-5

Microalbuminuria indicates early kidney damage and cardiovascular risk. Early detection and management are crucial for preventing disease progression and improving outcomes.

Abstract | Full Text |PDF (159 KB) | Open Access Article


Published online 08 July 2020

Phytochemicals in Cancer with Special Emphasis on Ovarian Cancer

Meher U Nessa1,2, Md S Anwar1, Fazlul Huq3*

pp. 156-166

Reviews current literature on use of phytochemicals in prevention and therapy of ovarian cancer including mechanism of action.

Abstract | Full Text |PDF (1 MB) |Supplementary Material | Open Access Article


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These articles have been peer reviewed and accepted for publication. They are still in production and have not been edited, so may differ from the final published form.

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