Journal of Angiotherapy
Angiogenesis, Inflammation & Therapeutics | Online ISSN  2207-872X
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RESEARCH ARTICLE   (Open Access)
Contents Vol 8 (9)

Shatadhauta Ghrita and Panchavalkala Prevent Wound Healing In Vivo

Tripti Dewangan 1*, Kishor Kumar Sahu 1

+ Author Affiliations

Journal of Angiotherapy 8 (9) 1-5 https://doi.org/10.25163/angiotherapy.899882

Submitted: 14 July 2024 Revised: 03 September 2024  Published: 09 September 2024 

Abstract

Background: Wounds disrupt the integrity of skin or mucosa, causing significant cellular and vascular damage. Historical and modern research aims to improve wound healing through effective management strategies and therapeutic applications, particularly within traditional systems like Ayurveda. This study evaluates the efficacy of Shatadhauta Ghrita (SDG) combined with Panchavalkala Siddha Ghrita (PSSG) for wound healing, assessing their potential as modern treatments. Methods: Thirty mature Wistar strain albino rats were divided into five groups, including a control and treatment groups receiving SDG, Go-Ghrita (GH), and PSSG. Standardized excision wounds were created, and healing was monitored through wound contraction measurements over 21 days. Results: The control group showed a wound contraction of 91.53% after 15 days, increasing to 95.23% by day 21. The GH group exhibited 93.67%, while the SDG group had 87.95%. Notably, the SDG group demonstrated a contraction of 98.67% by day 21, outperforming both control and GH groups. Conclusion: SDG’s superior wound healing efficacy suggests it may serve as an effective topical treatment, supported by traditional Ayurvedic practices. This research emphasizes the importance of integrating traditional knowledge with scientific validation, advocating for further studies on SDG's biological properties and potential applications in modern medicine.

Keywords: Wound healing, Shatadhauta Ghrita, Panchavalkala, Ayurveda, SDG, rat model.

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