Angiogenesis, Inflammation & Therapeutics | Online ISSN  2207-872X

Journal of Angiotherapy

Volume 8 Number 4 2024

Descriptive Table of Contents


Published online 01 April 2024

A Comprehensive Review of the Pharmacology of Statins and its Clinical Implications

Athiban Inbarajan 1*, Giri GVV 2, Anusha D 3, Alan Mathew Punnoose 4, Jasline David J 5, Mubeena S 6

pp. 1-6

The study aims to provide a detailed understanding of statins, their pharmacodynamics, and the various types involved as beneficial agents in the treatment of bone resorption and hypercholesterolemia.

Abstract | Full Text | PDF (355 KB) | Open Access Article

  

Published online 02 April 2024

Comparing Apixaban vs Rivaroxaban for Atrial Fibrillation Patients: An Effectiveness and Safety Analysis

Ghaida Fahad S Mubki 1, Mohmad Saad M Al Karani 1, Ahmed Saeed Abdullah 1, Tahani Mahmoud M Riyahi 1, Reem Abdulaziz Abdullah 1, Maha Mubarak Hamas Alotaibi 1, Amal Abdullah Faraj Hassan 2, Ahmed awad ali Zahrani 3, Nada Abdulrahman Hamad Altooq 1, Anfal Khalid Zain Bajamal 1, Nada saleh mohammad aldahaiman 1, Sajeda Qasim Abdulaziz Binjumaiah 1, Afaf Eesa Alsaggar Alenizi 1

pp. 1-13

Abstract | Full Text | PDF (341 KB) | Open Access Article

  

Published online 04 April 2024

Ensemble Deep Learning based Lung Cancer Classification Model using Gene Expression Data

V. Yuvaraj 1*, D. Maheswari 2

pp. 1-9

Precision medicine, microarray analysis, ensemble learning, and deep neural networks revolutionize lung cancer diagnosis, enhancing accuracy and treatment efficacy.

Abstract | Full Text | PDF (633 KB) | Open Access Article

  

Published online 04 April 2024

The Neutrophil/Lymphocyte Ratio in Helicobacter pylori Infected Patients:  A Comparative Therapeutic Study to Reduce Risk of Gastric Cancer

Dhifaf R. Reesn 1, Majid S. Jabir 2*

pp. 1-13

The study investigated Helicobacter pylori infection, its impact on inflammatory markers, and treatment efficacy, offering insights into diagnosis and management.

Abstract | Full Text | PDF (614 KB) | Open Access Article

  

Published online 04 April 2024

Biological Effectiveness of Seed Extracts of Some Species From Brassicaceae Family Against Two Types of Pathogenic Bacteria

Afnan Esam Adnan 1*, Wisam Malik Dawood 1*

pp. 1-9

Cruciferous Plant-derived compounds showed diverse medicinal properties, combating antibiotic resistance, providing therapeutic alternatives, and inhibiting biofilm formation in pathogenic bacteria.

Abstract | Full Text | PDF (248 KB) | Open Access Article

  

Published online 04 April 2024

Copper Toxicity and Calcium Supplementation on nkx2.5 and mt2 Gene Expression in Zebrafish Embryos

Sahib Mohammad bakir 1*, Theodore B. Henry 2, Richard D. Handy 3

pp. 1-8

This study determined how copper toxicity and calcium supplementation affect gene expression in early zebrafish embryos to inform aquatic environmental health and developmental biology.

Abstract | Full Text | PDF (263 KB) | Open Access Article

  

Published online 05 April 2024

Synthesis, Characterization, and Antimicrobial Activity of Spiro Heterocyclic Compounds from Statin

Zubaida Amir Al-Heety 1, Ali Kareem Al-Nasseri 2*

pp. 1-12

The study elucidated the synthesis, structural characterization, and diverse biological activities of spiro heterocyclic compounds.

Abstract | Full Text | PDF (683 KB) |Supplementary Material | Open Access Article

  

Published online 06 April 2024

The PIK3CA Mutation in Advanced Breast Cancer Chemoresistance and Recurrence

Movchan Oleksii Volodimirovich 1*, Smolanka Ivan Ivanovich 1, Lyashenko Andriy Oleksandrovich 1, Loboda Anton Dmitrovich 1, Dosenko Irina Viktorivna 1, Dosenko Irina Viktorivna 1, Ivankova Oksana Mykolaivna 1

pp. 1-5

This study demonstrated PIK3CA mutations' role in chemoresistance and recurrence informs targeted therapies, potentially improving outcomes for advanced breast cancer patients.

Abstract | Full Text | PDF (271 KB) | Open Access Article

  

Published online 06 April 2024

Antibacterial Activity of Sidr (Ziziphus spina-christi) Plant Extracts against Urinary Pathogens

Amal Naif Alshammari 1*

pp. 1-6

Sidr plant extracts showed promising antibacterial activity against urinary pathogens as potential alternative of UTI treatments.

Abstract | Full Text | PDF (211 KB) | Open Access Article

  

Published online 06 April 2024

Elevated Co-infection in Hepatitis C Virus and Toxoplasmosis Patients With IL-32, IL-33 and TNF-α

Amjad T. Hameed  1*, Nazar Sh. Mohammed 1, Amani M. Jasim 1

pp. 1-9

The co-occurrence of HCV and toxoplasmosis presents severe health risks, including liver damage and exacerbated symptoms. Understanding cytokine dynamics is crucial for targeted therapies.

Abstract | Full Text | PDF (558 KB) |Supplementary Material | Open Access Article

  

Published online 06 April 2024

A Comparative Study of Serological and Stool Antigen Tests for Helicobacter pylori Infection Diagnosis

Shler Ali Khorsheed 1*

pp. 1-6

Accurate diagnosis of Helicobacter pylori infection is crucial due to its association with gastrointestinal diseases, including ulcers and cancer.

Abstract | Full Text | PDF (237 KB) | Open Access Article

  

Published online 06 April 2024

Lymphocyte, IL-10, IL-6, and IFN-g Cytokines Modulation in SARS-CoV-2 Patients

Inaam Ali Abid 1*, Ismail Ibrahim Latif 2, Namer Fadhil Ghaab 3, Saad Ahmed Ali Jadoo 4

pp. 1-8

The study showed gender disparities in COVID-19 severity, revealing elevated cytokine levels of IL-10, IL-6, and IFN-g in males, as a potential immune response variations.

Abstract | Full Text | PDF (308 KB) | Open Access Article

  

Published online 06 April 2024

Liver Stiffness and Fibrosis Used as Early Diagnosis of Patients with Chronic Liver Disease in A Retrospective Cross-Sectional Study

Ahmed Saadi Mohammed 1*, Hiwa Abubakr Hussein 2, Saad Ahmed Ali Jadoo 3, Mohanned H. Alsalaumy 4, Laith Falah Hassan 5, Muhammad Rasul Hussein 6

pp. 1-7

Early diagnosis of chronic liver disease is vital for intervention. Transient elastography aids in predicting fibrosis, guiding treatment decisions effectively.

Abstract | Full Text | PDF (316 KB) | Open Access Article

  

Published online 06 April 2024

Molecular Detection of NDM-1 and ugpE Genes in Multidrug-Resistant Klebsiella pneumoniae Isolates and Their Correlation with Antibiotic Resistance

Zahraa Redha Shamsee 1*, Aida Hussain Ibrahim 1

pp. 1-8

Klebsiella pneumoniae shows a global threat due to its multidrug resistance. This study elucidated resistance mechanisms and antibiotic susceptibility, crucial for treatment strategies.

Abstract | Full Text | PDF (1 MB) | Open Access Article

  

Published online 06 April 2024

Ultra Micro Determination of Sulphonamide Through Oxidative Coupling Reaction Using Diazotized Promethazine

Ahmed Jassim Muklive Al-Ogaidi 1*, Hamssa Ahmed Easa 1, Shaymaa S. Hassan 1, Firas Al-Oqaili 1, Liblab S. Jassim 1

pp. 1-7

Spectrophotometric evaluation of sulphonamide using azo compounds offers a rapid, sensitive, and cost-effective method for quantitative pharmaceutical analysis.

Abstract | Full Text | PDF (506 KB) | Open Access Article

  

Published online 07 April 2024

Understanding Hematohidrosis: A Rare Phenomenon in Infancy - Case Report

Khamees M. Al-Dulaimy 1*

pp. 1-5

This case highlights the diagnostic challenges and successful management of hematohidrosis in infants, shedding light on effective treatment strategies.

Abstract | Full Text | PDF (361 KB) | Open Access Article

  

Published online 07 April 2024

A Rapid Diagnosis Development of Canine Enteric Coronavirus Inflammation

Mohammed Ali Hussein 1,2*, Mawlood Abbas Ali Al-Graibawi 1

pp. 1-8

This study elucidated the prevalence of CECoV in Baghdad, Iraq, highlighting its zoonotic potential and emphasizing the importance of surveillance and diagnostic tools.

Abstract | Full Text | PDF (284 KB) | Open Access Article

  

Published online 07 April 2024

Homocysteine and Visfatin Upregulation for Type 2 Diabetes Etiology

Sabaa Ahmed 1, Abdul-Rahim A. Ali 2, Murooj G. Jameel 2*, Mayada Talal Hamoo 2,  Mohammed fawzi majeed 2, Dina Suhail M Saleh 2, Sarah Hussain Khalaf 2

pp. 1-6

This study showed homocysteine and visfatin levels in diabetes offered insights into pathogenesis and potential therapeutic targets for managing complications.

Abstract | Full Text | PDF (227 KB) | Open Access Article

  

Published online 07 April 2024

Immunomodulatory Effects of Moringa oleifera Seed Extract and Nano Zinc Oxide on Benzene-Induced Toxicity In-Vivo

Shirin Jazar Amin 1*, Ayyub J. Abdl-Rhmaan Al-Bayaty 1, Salah M. A. Alkubaisi 2

pp. 1-5

This study addressed the critical need for antidotes against benzene toxicity, highlighting Moringa oleifera's potential immunomodulatory effects.

Abstract | Full Text | PDF (210 KB) | Open Access Article

  

Published online 07 April 2024

Quercus infectoria Bark Extract Shows Antibacterial Activity Against Staphylococcus Species

 Zainab Ahmed Aziz 1*, Siham Jasim Al Kaabi 1

pp. 1-6

This study determined the effect of Quercus infectoria bark as antibiotic and its resistance in bacterial infections.

Abstract | Full Text | PDF (496 KB) | Open Access Article

  

Published online 07 April 2024

Real-Time PCR Diagnosis of COVID-19 in Al Anbar Province, Iraq

Mohammed A. Hamad 1*, Firas R. Jameel 1, Noor Najm Abdullah 1, Muhaidi MJ 2

pp. 1-6

Accurate diagnosis with real-time PCR is essential for pandemic control. Understanding transmission dynamics aids in formulating effective public health measures.

Abstract | Full Text | PDF (583 KB) | Open Access Article

  

Published online 07 April 2024

Differential Expression of Annexin A1 Protein in Colorectal, Lung, and Liver Cancer Tissues

Hind Younis Khalaf 1, Nagam Khudhair 2*, Baydaa Abdul Sattar Atiyha 3

pp. 1-5

ANXA1's differential expression in colorectal, lung, and liver cancers could aid precise diagnosis and prognostication, guiding treatment decisions.

Abstract | Full Text | PDF (1 MB) | Open Access Article

  

Published online 08 April 2024

Serum miRNAs as Potential Diagnostic Biomarkers for Non-Obstructive Azoospermia

Fatima Mahdi Kadhum 1*, Ali Ibrahim Rahim 2, Ula Al-Kawaz 1

pp. 1-5

Identifying serum miRNAs aids in diagnosing non-obstructive azoospermia non-invasively, crucial for effective male infertility management.

Abstract | Full Text | PDF (181 KB) | Open Access Article

  

Published online 08 April 2024

Green Synthesis, Lead Toxicity and Pharmacokinetic Evaluation of Sumac Silver Nanoparticles In Vivo

Ammar H. Salman 1*, Mohammed Mosleh Shwaish 1

pp. 1-7

Sumac-synthesized silver nanoparticles (SAgNP) showed an eco-friendly approach to reduce blood lead levels, promising safer, cost-effective lead detoxification.

Abstract | Full Text | PDF (521 KB) | Open Access Article

  

Published online 08 April 2024

TLR-4 Polymorphisms Shows The Genetic Susceptibility to Toxoplasmosis and Polycystic Ovary Syndrome

Haider Iskandar Flayh 1*, Al-Marsomy, Huda Dhaher 1, Khazaali, Enas Adnan Abdulrasol 2

pp. 1-8

In this study TLR-4 polymorphism showed a role on susceptibility to Toxoplasma gondii infection and polycystic ovary syndrome development.

Abstract | Full Text | PDF (308 KB) | Open Access Article

  

Published online 08 April 2024

Immunological and Molecular Analysis of Virulence and Resistance of Pseudomonas aeruginosa in Urinary Tract Infections

Zainab Hayder Jaber Alkufaishi 1, Lamees A. Abdul-Lateef 2 *, Anwar Kadhim Hussein AL-saffar 3, Jwan Ahmed Ali Alhamawandi 4

pp. 1-6

This study provided insights into the immunological and molecular aspects of Pseudomonas aeruginosa, informing targeted therapeutic strategies for urinary tract infections.

Abstract | Full Text | PDF (387 KB) | Open Access Article

  

Published online 08 April 2024

A Molecular Resistance Mechanisms Detection in Klebsiella pneumoniae through Carbapenem Enzymatic Genes

Halah Raheem Mohammed Almidhatee 1*, Zainab Hayder Jaber Alkufaishi 2, Anwar Kadhim Hussein AL-saffar 3, Jwan Ahmed Ali Alhamawandi 4

pp. 1-8

Identifying carbapenem resistance mechanisms in Klebsiella pneumoniae might be a treatment strategies against the rising antibiotic resistance globally.

Abstract | Full Text | PDF (909 KB) | Open Access Article

  

Published online 09 April 2024

Impact of Bacterial Infections on Semen Parameters in Sub-Fertile Men

 Muzdalifa Mejbel Fadwi 1,3*, Sawsan Q.T. Al-Quhli 1, Ziad H. Abd 2

pp. 1-8

This study demonstrated a correlation between bacterial infections and semen parameters, providing insights for precise therapy strategies in male sub-fertility.

Abstract | Full Text | PDF (442 KB) | Open Access Article

  

Published online 09 April 2024

Resveratrol Mitigates Acrylonitrile-induced Thyroid and Adrenal Toxicity in Rats

Samer I. Sabeeh 1*, Ahmed Q. Al-Awadi 1

pp. 1-8

Resveratrol counters acrylonitrile's adverse effects, preserving thyroid and adrenal function, evidenced hormonally and histologically, suggesting therapeutic potential.

Abstract | Full Text | PDF (2 MB) | Open Access Article

  

Published online 09 April 2024

Risk Assessment of Rheumatic Fever and Mitral Valve Stenosis in Samawah, Iraq

Salah Abd-Al Kader Omran 1*

pp. 1-8

This study showed that a multidimensional approach involving medical interventions and governmental recommendations can significantly reduce infections and mortality rates, particularly among children, which is important for public health strategies.

Abstract | Full Text | PDF (308 KB) | Open Access Article

  

Published online 09 April 2024

Anti-inflammatory and Antioxidant Activity of Rosemary Essential Oil

Duaa Y. Khalil 1, Omar M. Hassan 1*

 

pp. 1-6

This study proved that Rosemary essential oils have Anti-inflammatory and Antioxidant Properties.

Abstract | Full Text | PDF (368 KB) | Open Access Article

  

Published online 12 April 2024

Advances in Therapeutic Approach for Orthopaedic Surgery – A Review

Adnan Essa Al kilabi 1*

pp. 1-8

This review discussed the new therapeutic approach in orthopedic surgery.

Abstract | Full Text | PDF (193 KB) | Open Access Article

  

Published online 12 April 2024

Association Between Vitamin D Deficiency and Higher Body Mass Index Among Women of Various Age Groups in Samawah City

Safa Azhar Razzaq 1*

pp. 1-6

The study found that there was relationship between vitamin D levels and BMI values in female.

Abstract | Full Text | PDF (253 KB) | Open Access Article

  

Published online 12 April 2024

Assessing Listeria Monocytogenes Survival and Growth in Skim, Partial Skim, and Full-Fat Milk under Refrigeration

Marwa Mahmood 1*, Fouad K. Alsammarraie 1

pp. 1-8

This study revealed that preserving dairy products in refrigeration does not protect them from contamination with Listeria.

Abstract | Full Text | PDF (472 KB) | Open Access Article

  

Published online 12 April 2024

Natural Colorants Induce the Drug Release from Fast Dissolving Tablets

Esra Tariq Bayrakdar 1, Sharad Visht 1*, Duran Kala 2, Saya Ameer 1, Ahmed Hamdy 1, Sawsan S. Al-Rawi 3, Samir Bhargava 4, Abhijeet Ojha 5

pp. 1-12

This study showed the impact of hydrophilic and hydrophobic colorants on drug release, crucial for improving palatability and therapeutic efficacy of fast dissolving tablets.

Abstract | Full Text | PDF (617 KB) |Supplementary Material | Open Access Article

  

Published online 15 April 2024

Modeling Multifocal Atherosclerosis in Rabbits for Gender Influence and Lipid Profile Effects

Maksud M. Asadullayev 1, Khilola T. Mirakhmedova.2, Nataliya  L.Vipova 3, Albina V.Filatova 3, Rustam N. Jalolov 5, Doston R. Jumanazarov.5 , Nargiza M.Vaxabova 2, Ixtiyor T.Aliqulov 2, Sardoriddin Sh.Srojidinov 2

pp. 1-8

This study demonstrated a rabbit models as drug development and understanding atherosclerosis dynamics, which is vital for combating cardiovascular diseases globally.

Abstract | Full Text | PDF (469 KB) | Open Access Article

  

Published online 18 April 2024

Diagnostic Efficacy of Tumor Markers AFP, CA19-9, and CEA in Hepatocellular Carcinoma Patients

Tufael 1*, Auditi Kar 2, Md Haroon Or Rashid 3, Atiqur Rahman Sunny 4*, António Raposo 5, Md. Saidul Islam 6, Md. Anower Hussain 7, Mohammad Anowar Hussen 8, Heesup Han 9, Henrique Douglas Melo Coutinho 10, Md. Sefaut Ullah 11, Md. Mizanur Rahman12

pp. 1-10

Early detection of hepatocellular carcinoma (HCC) is vital for improving patient outcomes. Chemiluminescence assays showed enhanced diagnostic accuracy, providing timely intervention and treatment.

Abstract | Full Text | PDF (418 KB) | Open Access Article

  

Published online 22 April 2024

Advancing Lotion Formulation Research: Harnessing the Potential of Moringa oleifera and Shea Butter for Enhanced Skin Health

Rolla Al-Shalabi 1,2, Nozlena Abdul Samad 1*, Lim Vuanghao 1, Julia Joseph 1

pp. 1-5

The integration of Moringa oleifera nanoparticles and shea butter in lotion represents a groundbreaking milestone in skincare. This fusion offers profound benefits, including deep hydration and potent anti-inflammatory properties.

Abstract | Full Text | PDF (312 KB) | Open Access Article

  


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