References
Abdel Aziz, M. T., Motawi, T., Rezq, A., Mostafa, T., Fouad, H. H., Ahmed, H. H., Rashed, L., Sabry, D., Senbel, A., Al-Malki, A., & El-Shafiey, R. (2012). Effects of a water-soluble curcumin protein conjugate vs. pure curcumin in a diabetic model of erectile dysfunction. The Journal of Sexual Medicine, 9(7), 1815–1833. https://doi.org/10.1111/j.1743-6109.2012.02741.x
Agharazi, M., Gazerani, S., & Huntington, M. K. (2022). Topical turmeric ointment in treating diabetic foot ulcers: a randomized, placebo-controlled study. The International Journal of Lower Extremity Wounds, 15347346221143222. Advanced online publication. https://doi.org/10.1177/15347346221143222
Akkus, G., & Sert, M. (2022). Diabetic foot ulcers: A devastating complication of diabetes mellitus continues non-stop despite new medical treatment modalities. World Journal of Diabetes, 13(12), 1106–1121. https://doi.org/10.4239/wjd.v13.i12.1106
Ali Hussain H. E. (2002). Hypoglycemic, hypolipidemic and antioxidant properties of combination of Curcumin from Curcuma longa, Linn, and partially purified product from Abroma augusta, Linn. in streptozotocin induced diabetes. Indian Journal of Clinical Biochemistry: IJCB, 17(2), 33–43. https://doi.org/10.1007/BF02867969
Alicic, R. Z., Rooney, M. T., & Tuttle, K. R. (2017). Diabetic kidney disease: challenges, progress, and possibilities. Clinical Journal of the American Society of Nephrology: CJASN, 12(12), 2032–2045. https://doi.org/10.2215/CJN.11491116
Alshehri A. M. (2010). Metabolic syndrome and cardiovascular risk. Journal of Family & Community Medicine, 17(2), 73–78. https://doi.org/10.4103/1319-1683.71987
ALTamimi, J. Z., AlFaris, N. A., Al-Farga, A. M., Alshammari, G. M., BinMowyna, M. N., & Yahya, M. A. (2021). Curcumin reverses diabetic nephropathy in streptozotocin-induced diabetes in rats by inhibition of PKCβ/p66Shc axis and activation of FOXO-3a. The Journal of Nutritional Biochemistry, 87, 108515. https://doi.org/10.1016/j.jnutbio.2020.108515
Arli, M., & Celik, H. (2020). The biological importance of curcumin. Eastern Anatolian Journal of Science, 6(1), 21-34.
Ashwini, K., & Dash, R. (2023). Grading diabetic retinopathy using multiresolution based CNN. Biomedical Signal Processing and Control, 86, 105210.
Aumiller, W. D., & Dollahite, H. A. (2015). Pathogenesis and management of diabetic foot ulcers. JAAPA : Journal of American Academy of Physician Assistants, 28(5), 28–34. https://doi.org/10.1097/01.JAA.0000464276.44117.b1
Azhary, H., Farooq, M. U., Bhanushali, M., Majid, A., & Kassab, M. Y. (2010). Peripheral neuropathy: differential diagnosis and management. American Family Physician, 81(7), 887-892.
Baig, M. S., Banu, A., Zehravi, M., Rana, R., Burle, S. S., Khan, S. L., Islam, F., Siddiqui, F. A., Massoud, E. E. S., Rahman, M. H., & Cavalu, S. (2022). An overview of diabetic foot ulcers and associated problems with special emphasis on treatments with antimicrobials. Life (Basel, Switzerland), 12(7), 1054. https://doi.org/10.3390/life12071054
Barber A. J. (2015). Diabetic retinopathy: recent advances towards understanding neurodegeneration and vision loss. Science China. Life sciences, 58(6), 541–549. https://doi.org/10.1007/s11427-015-4856-x
Baynes J. W. (1991). Role of oxidative stress in development of complications in diabetes. Diabetes, 40(4), 405–412. https://doi.org/10.2337/diab.40.4.405
Bertoncini-Silva, C., Vlad, A., Ricciarelli, R., Giacomo Fassini, P., Suen, V. M. M., & Zingg, J. M. (2024). Enhancing the bioavailability and bioactivity of curcumin for disease prevention and treatment. Antioxidants, 13(3), 331.
Bhatti, J. S., Sehrawat, A., Mishra, J., Sidhu, I. S., Navik, U., Khullar, N., ... & Reddy, P. H. (2022). Oxidative stress in the pathophysiology of type 2 diabetes and related complications: Current therapeutics strategies and future perspectives. Free Radical Biology and Medicine, 184, 114-134.
Boulton, A. J., Vinik, A. I., Arezzo, J. C., Bril, V., Feldman, E. L., Freeman, R., Malik, R. A., Maser, R. E., Sosenko, J. M., Ziegler, D., & American Diabetes Association (2005). Diabetic neuropathies: a statement by the American Diabetes Association. Diabetes Care, 28(4), 956–962. https://doi.org/10.2337/diacare.28.4.956
Bragg, S., Marrison, S. T., & Haley, S. (2024). Diabetic Peripheral Neuropathy: Prevention and Treatment. American Family Physician, 109(3), 226–232.
Çakici, N., Fakkel, T. M., van Neck, J. W., Verhagen, A. P., & Coert, J. H. (2016). Systematic review of treatments for diabetic peripheral neuropathy. Diabetic Medicine, 33(11), 1466–1476. https://doi.org/10.1111/dme.13083.
Cao, M., Duan, Z., Wang, X., Gong, P., Zhang, L., & Ruan, B. (2024). Curcumin promotes diabetic foot ulcer wound healing by inhibiting miR-152-3p and activating the FBN1/TGF-β pathway. Molecular Biotechnology, 66(5), 1266–1278. https://doi.org/10.1007/s12033-023-01027-z
Caturano, A., D'Angelo, M., Mormone, A., Russo, V., Mollica, M. P., Salvatore, T., Galiero, R., Rinaldi, L., Vetrano, E., Marfella, R., Monda, M., Giordano, A., & Sasso, F. C. (2023). Oxidative Stress in Type 2 Diabetes: Impacts from Pathogenesis to Lifestyle Modifications. Current Issues in Molecular Biology, 45(8), 6651–6666. https://doi.org/10.3390/cimb45080420
Ceriello A. (2000). Oxidative stress and glycemic regulation. Metabolism: Clinical and Experimental, 49(2 Suppl 1), 27–29. https://doi.org/10.1016/s0026-0495(00)80082-7
Cernea, S., & Raz, I. (2021). Management of diabetic neuropathy. Metabolism, 123, 154867. https://doi.org/10.1016/j.metabol.2021.154867
Chaudhary, P., Janmeda, P., Docea, A. O., Yeskaliyeva, B., Abdull Razis, A. F., Modu, B., Calina, D., & Sharifi-Rad, J. (2023). Oxidative stress, free radicals and antioxidants: potential crosstalk in the pathophysiology of human diseases. Frontiers in Chemistry, 11, 1158198. https://doi.org/10.3389/fchem.2023.1158198
Cheng, Y. W., Huang, Y. C., Chang, K. F., Huang, X. F., Sheu, G. T., & Tsai, N. M. (2024). Protective Effect of Curcumin on the Tight Junction Integrity and Cellular Senescence in Human Retinal Pigment Epithelium of Early Diabetic Retinopathy. Journal of Physiological Investigation, 67(3), 107–117. https://doi.org/10.4103/ejpi.EJPI-D-23-00035
Darenskaya, M. A., Kolesnikova, L. I., & Kolesnikov, S. I. (2021). Oxidative Stress: Pathogenetic Role in Diabetes Mellitus and Its Complications and Therapeutic Approaches to Correction. Bulletin of Experimental Biology and Medicine, 171(2), 179–189. https://doi.org/10.1007/s10517-021-05191-7
Davis, B. M., Pahlitzsch, M., Guo, L., Balendra, S., Shah, P., Ravindran, N., Malaguarnera, G., Sisa, C., Shamsher, E., Hamze, H., Noor, A., Sornsute, A., Somavarapu, S., & Cordeiro, M. F. (2018). Topical Curcumin Nanocarriers are Neuroprotective in Eye Disease. Scientific Reports, 8(1), 11066. https://doi.org/10.1038/s41598-018-29393-8
Deshpande, A. D., Harris-Hayes, M., & Schootman, M. (2008). Epidemiology of diabetes and diabetes-related complications. Physical Therapy, 88(11), 1254–1264. https://doi.org/10.2522/ptj.20080020
Dilworth, L., Facey, A., & Omoruyi, F. (2021). Diabetes mellitus and its metabolic complications: the role of adipose tissues. International Journal of Molecular Sciences, 22(14), 7644.
Dludla, P. V., Mabhida, S. E., Ziqubu, K., Nkambule, B. B., Mazibuko-Mbeje, S. E., Hanser, S., Basson, A. K., Pheiffer, C., & Kengne, A. P. (2023). Pancreatic β-cell dysfunction in type 2 diabetes: Implications of inflammation and oxidative stress. World Journal of Diabetes, 14(3), 130–146. https://doi.org/10.4239/wjd.v14.i3.130
Dos Santos, J. M., de Oliveira, D. S., Moreli, M. L., & Benite-Ribeiro, S. A. (2018). The role of mitochondrial DNA damage at skeletal muscle oxidative stress on the development of type 2 diabetes. Molecular and Cellular Biochemistry, 449(1-2), 251–255. https://doi.org/10.1007/s11010-018-3361-5
Dos Santos, J. M., Tewari, S., & Mendes, R. H. (2019). The role of oxidative stress in the development of diabetes mellitus and its complications. Journal of Diabetes Research, 2019, 4189813. https://doi.org/10.1155/2019/4189813
Draganski, A., Tar, M. T., Villegas, G., Friedman, J. M., & Davies, K. P. (2018). Topically Applied Curcumin-Loaded Nanoparticles Treat Erectile Dysfunction in a Rat Model of Type-2 Diabetes. The Journal of Sexual Medicine, 15(5), 645–653. https://doi.org/10.1016/j.jsxm.2018.03.009
Edwards, J. L., Vincent, A. M., Cheng, H. T., & Feldman, E. L. (2008). Diabetic neuropathy: mechanisms to management. Pharmacology & Therapeutics, 120(1), 1–34. https://doi.org/10.1016/j.pharmthera.2008.05.005
Eguchi, N., Vaziri, N. D., Dafoe, D. C., & Ichii, H. (2021). The Role of Oxidative Stress in Pancreatic β Cell Dysfunction in Diabetes. International Journal of Molecular Sciences, 22(4), 1509. https://doi.org/10.3390/ijms22041509
Elsayed, H. R. H., Rabei, M. R., Elshaer, M. M. A., El Nashar, E. M., Alghamdi, M. A., Al-Qahtani, Z., & Nabawy, A. (2023). Suppression of neuronal apoptosis and glial activation with modulation of Nrf2/HO-1 and NF-kB signaling by curcumin in streptozotocin-induced diabetic spinal cord central neuropathy. Frontiers in Neuroanatomy, 17, 1094301. https://doi.org/10.3389/fnana.2023.1094301
Entezari, M., Hashemi, D., Taheriazam, A., Zabolian, A., Mohammadi, S., Fakhri, F., ... & Samarghandian, S. (2022). AMPK signaling in diabetes mellitus, insulin resistance and diabetic complications: A pre-clinical and clinical investigation. Biomedicine & Pharmacotherapy, 146, 112563.
Feldman, E. L., Callaghan, B. C., Pop-Busui, R., Zochodne, D. W., Wright, D. E., Bennett, D. L., Bril, V., Russell, J. W., & Viswanathan, V. (2019). Diabetic neuropathy. Nature Reviews. Disease Primers, 5(1), 42. https://doi.org/10.1038/s41572-019-0097-9
Gaschler, M. M., & Stockwell, B. R. (2017). Lipid peroxidation in cell death. Biochemical and Biophysical Research Communications, 482(3), 419-425.
Ghasemi, H., Einollahi, B., Kheiripour, N., Hosseini-Zijoud, S. R., & Farhadian Nezhad, M. (2019). Protective effects of curcumin on diabetic nephropathy via attenuation of kidney injury molecule 1 (KIM-1) and neutrophil gelatinase-associated lipocalin (NGAL) expression and alleviation of oxidative stress in rats with type 1 diabetes. Iranian Journal of Basic Medical Sciences, 22(4), 376–383. https://doi.org/10.22038/ijbms.2019.31922.7674
Giacco, F., & Brownlee, M. (2010). Oxidative stress and diabetic complications. Circulation Research, 107(9), 1058–1070. https://doi.org/10.1161/CIRCRESAHA.110.223545
González, P., Lozano, P., Ros, G., & Solano, F. (2023). Hyperglycemia and oxidative stress: an integral, updated and critical overview of their metabolic interconnections. International Journal of Molecular Sciences, 24(11), 9352. https://doi.org/10.3390/ijms24119352
Gorain, B., Pandey, M., Leng, N. H., Yan, C. W., Nie, K. W., Kaur, S. J., ... & Choudhury, H. (2022). Advanced drug delivery systems containing herbal components for wound healing. International Journal of Pharmaceutics, 617, 121617.
Gu, Y., Niu, Q., Zhang, Q., & Zhao, Y. (2024). Ameliorative Effects of Curcumin on Type 2 Diabetes Mellitus. Molecules, 29(12), 2934.
Gupta, S. K., Kumar, B., Nag, T. C., Agrawal, S. S., Agrawal, R., Agrawal, P., Saxena, R., & Srivastava, S. (2011). Curcumin prevents experimental diabetic retinopathy in rats through its hypoglycemic, antioxidant, and anti-inflammatory mechanisms. Journal of Ocular Pharmacology and Therapeutics, 27(2), 123–130. https://doi.org/10.1089/jop.2010.0123
Gurgul-Convey, E., Mehmeti, I., Plötz, T., Jörns, A., & Lenzen, S. (2016). Sensitivity profile of the human EndoC-βH1 beta cell line to proinflammatory cytokines. Diabetologia, 59(10), 2125–2133. https://doi.org/10.1007/s00125-016-4060-y
Hoogeveen, E. K. (2022). The epidemiology of diabetic kidney disease. Kidney and Dialysis, 2(3), 433-442.
International Diabetes Federation. IDF Diabetes Atlas 10th edition. International Diabetes Federation, 2021. https://diabetesatlas.org/atlas/tenth-edition/
Jabczyk, M., Nowak, J., Hudzik, B., & Zubelewicz-Szkodzinska, B. (2021). Curcumin in metabolic health and disease. Nutrients, 13(12), 4440.
Jia, T., Rao, J., Zou, L., Zhao, S., Yi, Z., Wu, B., Li, L., Yuan, H., Shi, L., Zhang, C., Gao, Y., Liu, S., Xu, H., Liu, H., Liang, S., & Li, G. (2018). Nanoparticle-encapsulated curcumin inhibits diabetic neuropathic pain involving the P2Y12 receptor in the dorsal root ganglia. Frontiers in Neuroscience, 11, 755. https://doi.org/10.3389/fnins.2017.00755
Juan, C. A., Pérez de la Lastra, J. M., Plou, F. J., & Pérez-Lebeña, E. (2021). The chemistry of reactive oxygen species (ROS) revisited: outlining their role in biological macromolecules (DNA, lipids and proteins) and induced pathologies. International Journal of Molecular Sciences, 22(9), 4642.
Kao, Y. W., Hsu, S. K., Chen, J. Y. F., Lin, I. L., Chen, K. J., Lee, P. Y., ... & Cheng, K. C. (2020). Curcumin metabolite tetrahydrocurcumin in the treatment of eye diseases. International Journal of Molecular Sciences, 22(1), 212. https://doi.org/10.3390/ijms22010212
Khalid Ibrahim, I., Antoni, A., & Susanti, I. (2024). Implementation of Combination of Curcumin Gel and Honey for the Treatment of Diabetic Foot Ulcer: A Pre-Experimental Study. Journal of Wound Research and Technology, 1(1), 38–45. https://doi.org/10.70196/jwrt.v1i1.6
Khan, J., & Shaw, S. (2023). Risk of cataract and glaucoma among older persons with diabetes in India: a cross-sectional study based on LASI, Wave-1. Scientific Reports, 13(1), 11973.
Kim, T., Davis, J., Zhang, A. J., He, X., & Mathews, S. T. (2009). Curcumin activates AMPK and suppresses gluconeogenic gene expression in hepatoma cells. Biochemical and Biophysical Research Communications, 388(2), 377-382.
Kour, V., Swain, J., Singh, J., Singh, H., & Kour, H. (2024). A Review on Diabetic Retinopathy. Current Diabetes Reviews, 20(6), e201023222418. https://doi.org/10.2174/0115733998253672231011161400
Kumar, A., Gangwar, R., Zargar, A. A., Kumar, R., & Sharma, A. (2024). Prevalence of Diabetes in India: A Review of IDF Diabetes Atlas 10th Edition. Current Diabetes Reviews, 20(1), e130423215752. https://doi.org/10.2174/1573399819666230413094200
Landrum, O., Marcondes, L., Egharevba, T., & Gritsenko, K. (2023). Painful diabetic peripheral neuropathy of the feet: integrating prescription-strength capsaicin into office procedures. Pain Management, 13(10), 613–626. https://doi.org/10.2217/pmt-2023-0028
Leon, B. M., & Maddox, T. M. (2015). Diabetes and cardiovascular disease: Epidemiology, biological mechanisms, treatment recommendations and future research. World Journal of Diabetes, 6(13), 1246–1258. https://doi.org/10.4239/wjd.v6.i13.1246
Li, J., Wang, P., Ying, J., Chen, Z., & Yu, S. (2016). Curcumin Attenuates Retinal Vascular Leakage by Inhibiting Calcium/Calmodulin-Dependent Protein Kinase II Activity in Streptozotocin-Induced Diabetes. Cellular Physiology and Biochemistry, 39(3), 1196–1208. https://doi.org/10.1159/000447826
Li, J., Wang, P., Zhu, Y., Chen, Z., Shi, T., Lei, W., & Yu, S. (2015). Curcumin Inhibits Neuronal Loss in the Retina and Elevates Ca²?/Calmodulin-Dependent Protein Kinase II Activity in Diabetic Rats. Journal of Ocular Pharmacology and Therapeutics, 31(9), 555–562. https://doi.org/10.1089/jop.2015.0006
Li, L., Liu, S., Zhou, Y., Zhao, M., Wang, Y., Wang, C., Lou, P., Huang, R., Ma, L., Lu, Y., Fu, P., & Liu, J. (2021). Indispensable role of mitochondria in maintaining the therapeutic potential of curcumin in acute kidney injury. Journal of Cellular and Molecular Medicine, 25(20), 9863–9877. https://doi.org/10.1111/jcmm.16934
Lin, Z., Wang, S., Cao, Y., Lin, J., Sun, A., Huang, W., Zhou, J., & Hong, Q. (2024). Bioinformatics and validation reveal the potential target of curcumin in the treatment of diabetic peripheral neuropathy. Neuropharmacology, 260, 110131. Advance online publication. https://doi.org/10.1016/j.neuropharm.2024.110131
Lu, M., Yin, N., Liu, W., Cui, X., Chen, S., & Wang, E. (2017). Curcumin Ameliorates Diabetic Nephropathy by Suppressing NLRP3 Inflammasome Signaling. BioMed Research International, 2017, 1516985. https://doi.org/10.1155/2017/1516985
Luc, K., Schramm-Luc, A., Guzik, T. J., & Mikolajczyk, T. P. (2019). Oxidative stress and inflammatory markers in prediabetes and diabetes. Journal of Physiology and Pharmacology, 70(6), 10.26402/jpp.2019.6.01. https://doi.org/10.26402/jpp.2019.6.01
Lv, J., Cao, L., Zhang, R., Bai, F., & Wei, P. (2018). A curcumin derivative J147 ameliorates diabetic peripheral neuropathy in streptozotocin (STZ)-induced DPN rat models through negative regulation AMPK on TRPA1. Acta Cirurgica Brasileira, 33(6), 533–541. https://doi.org/10.1590/s0102-865020180060000008
Maiorino, M. I., Bellastella, G., & Esposito, K. (2014). Diabetes and sexual dysfunction: current perspectives. Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy, 7, 95–105. https://doi.org/10.2147/DMSO.S36455
Masenga, S. K., Kabwe, L. S., Chakulya, M., & Kirabo, A. (2023). Mechanisms of oxidative stress in metabolic syndrome. International Journal of Molecular Sciences, 24(9), 7898.
McLennan, S. V., Heffernan, S., Wright, L., Rae, C., Fisher, E., Yue, D. K., & Turtle, J. R. (1991). Changes in hepatic glutathione metabolism in diabetes. Diabetes, 40(3), 344–348. https://doi.org/10.2337/diab.40.3.344
Miao, C., Chen, H., Li, Y., Guo, Y., Xu, F., Chen, Q., Zhang, Y., Hu, M., & Chen, G. (2021). Curcumin and its analog alleviate diabetes-induced damages by regulating inflammation and oxidative stress in brain of diabetic rats. Diabetology & Metabolic Syndrome, 13(1), 21. https://doi.org/10.1186/s13098-021-00638-3
Minaz, N., Razdan, R., Hammock, B. D., Mujwar, S., & Goswami, S. K. (2019). Impact of diabetes on male sexual function in streptozotocin-induced diabetic rats: Protective role of soluble epoxide hydrolase inhibitor. Biomedicine & Pharmacotherapy, 115, 108897. https://doi.org/10.1016/j.biopha.2019.108897
Mullarkey, C. J., Edelstein, D., & Brownlee, M. (1990). Free radical generation by early glycation products: a mechanism for accelerated atherogenesis in diabetes. Biochemical and Biophysical Research Communications, 173(3), 932–939. https://doi.org/10.1016/s0006-291x(05)80875-7
Nunes, Y. C., Mendes, N. M., Pereira de Lima, E., Chehadi, A. C., Lamas, C. B., Haber, J. F., ... & Marin, M. J. S. (2024). Curcumin: A Golden Approach to Healthy Aging: A Systematic Review of the Evidence. Nutrients, 16(16), 2721.
Ogbonnaya, F. C., Amah, H. G., Ugwu, J. C., Akani, E.O., Karigdi, K.O., & Ahanonu, I. S. (2023). Ameliorating effects of curcumin on diabetes. Dutse Journal of Pure and Applied Sciences, 9(4a), 310-319, https://dx.doi.org/10.4314/dujopas.v9i4a.29
Oguntibeju O. O. (2019). Type 2 diabetes mellitus, oxidative stress and inflammation: examining the links. International Journal of Physiology, Pathophysiology and Pharmacology, 11(3), 45–63.
Peddada, K. V., Brown, A., Verma, V., & Nebbioso, M. (2019). Therapeutic potential of curcumin in major retinal pathologies. International Ophthalmology, 39(3), 725–734. https://doi.org/10.1007/s10792-018-0845-y
Peng, Y., Ao, M., Dong, B., Jiang, Y., Yu, L., Chen, Z., Hu, C., & Xu, R. (2021). Anti-inflammatory effects of curcumin in the inflammatory diseases: status, limitations and countermeasures. Drug Design, Development and Therapy, 15, 4503–4525. https://doi.org/10.2147/DDDT.S327378
Platania, C. B. M., Fidilio, A., Lazzara, F., Piazza, C., Geraci, F., Giurdanella, G., Leggio, G. M., Salomone, S., Drago, F., & Bucolo, C. (2018). Retinal protection and distribution of curcumin in vitro and in vivo. Frontiers in Pharmacology, 9, 670. https://doi.org/10.3389/fphar.2018.00670
Prabhakar S. S. (2017). Effects of curcumin in experimental diabetic nephropathy. Journal of Investigative Medicine, 65(1), 1–6. https://doi.org/10.1136/jim-2016-000272
Quispe, C., Herrera-Bravo, J., Javed, Z., Khan, K., Raza, S., Gulsunoglu-Konuskan, Z., Dastan, S. D., Sytar, O., Martorell, M., Sharifi-Rad, J., & Calina, D. (2022). Therapeutic applications of curcumin in diabetes: a review and perspective. BioMed Research International, 2022, 1375892. https://doi.org/10.1155/2022/1375892
Racz, L. Z., Racz, C. P., Pop, L. C., Tomoaia, G., Mocanu, A., Barbu, I., ... & Toma, V. A. (2022). Strategies for improving bioavailability, bioactivity, and physical-chemical behavior of curcumin. Molecules, 27(20), 6854.
Radomska-Lesniewska, D. M., Osiecka-Iwan, A., Hyc, A., Gózdz, A., Dabrowska, A. M., & Skopinski, P. (2019). Therapeutic potential of curcumin in eye diseases. Central-European Journal of Immunology, 44(2), 181–189. https://doi.org/10.5114/ceji.2019.87070
Rashid, K., Chowdhury, S., Ghosh, S., & Sil, P. C. (2017). Curcumin attenuates oxidative stress induced NFκB mediated inflammation and endoplasmic reticulum dependent apoptosis of splenocytes in diabetes. Biochemical Pharmacology, 143, 140–155. https://doi.org/10.1016/j.bcp.2017.07.009
Rask-Madsen, C., & King, G. L. (2013). Vascular complications of diabetes: mechanisms of injury and protective factors. Cell Metabolism, 17(1), 20–33. https://doi.org/10.1016/j.cmet.2012.11.012
Ren, B. C., Zhang, Y. F., Liu, S. S., Cheng, X. J., Yang, X., Cui, X. G., Zhao, X. R., Zhao, H., Hao, M. F., Li, M. D., Tie, Y. Y., Qu, L., & Li, X. Y. (2020). Curcumin alleviates oxidative stress and inhibits apoptosis in diabetic cardiomyopathy via Sirt1-Foxo1 and PI3K-Akt signalling pathways. Journal of Cellular and Molecular Medicine, 24(21), 12355–12367. https://doi.org/10.1111/jcmm.15725
Roxo, D. F., Arcaro, C. A., Gutierres, V. O., Costa, M. C., Oliveira, J. O., Lima, T. F. O., Assis, R. P., Brunetti, I. L., & Baviera, A. M. (2019). Curcumin combined with metformin decreases glycemia and dyslipidemia, and increases paraoxonase activity in diabetic rats. Diabetology & Metabolic Syndrome, 11, 33. https://doi.org/10.1186/s13098-019-0431-0
Ruke, M., Iffat, Maurya, A., Bhise, A., Jose, J. A., et al. (2024). Effectiveness and Tolerability of Topical Curcumin for Management of Diabetic Foot Ulcer: A Pilot Clinical Study. International Journal of Diabetes and Endocrinology, 9(3), 56-60. https://doi.org/10.11648/j.ijde.20240903.11
Sagoo, M. K., & Gnudi, L. (2020). Diabetic nephropathy: an overview. Diabetic Nephropathy: Methods and Protocols, 3-7.
Salvatore, T., Pafundi, P. C., Galiero, R., Albanese, G., Di Martino, A., Caturano, A., Vetrano, E., Rinaldi, L., & Sasso, F. C. (2021). The Diabetic Cardiomyopathy: The Contributing Pathophysiological Mechanisms. Frontiers in Medicine, 8, 695792. https://doi.org/10.3389/fmed.2021.695792
Sathyabhama, M., Priya Dharshini, L. C., Karthikeyan, A., Kalaiselvi, S., & Min, T. (2022). The credible role of curcumin in oxidative stress-mediated mitochondrial dysfunction in mammals. Biomolecules, 12(10), 1405. https://doi.org/10.3390/biom12101405
Sharma, S., Kulkarni, S. K., & Chopra, K. (2006). Curcumin, the active principle of turmeric (Curcuma longa), ameliorates diabetic nephropathy in rats. Clinical and Experimental Pharmacology & Physiology, 33(10), 940–945. https://doi.org/10.1111/j.1440-1681.2006.04468.x
Soetikno, V., Sari, F. R., Veeraveedu, P. T., Thandavarayan, R. A., Harima, M., Sukumaran, V., Lakshmanan, A. P., Suzuki, K., Kawachi, H., & Watanabe, K. (2011a). Curcumin ameliorates macrophage infiltration by inhibiting NF-κB activation and proinflammatory cytokines in streptozotocin induced-diabetic nephropathy. Nutrition & Metabolism, 8(1), 35. https://doi.org/10.1186/1743-7075-8-35
Soetikno, V., Suzuki, K., Veeraveedu, P. T., Arumugam, S., Lakshmanan, A. P., Sone, H., & Watanabe, K. (2013). Molecular understanding of curcumin in diabetic nephropathy. Drug Discovery Today, 18(15-16), 756–763. https://doi.org/10.1016/j.drudis.2013.04.009
Soetikno, V., Watanabe, K., Sari, F. R., Harima, M., Thandavarayan, R. A., Veeraveedu, P. T., Arozal, W., Sukumaran, V., Lakshmanan, A. P., Arumugam, S., & Suzuki, K. (2011). Curcumin attenuates diabetic nephropathy by inhibiting PKC-α and PKC-β1 activity in streptozotocin-induced type I diabetic rats. Molecular Nutrition & Food Research, 55(11), 1655–1665. https://doi.org/10.1002/mnfr.201100080
Soto, C., Recoba, R., Barrón, H., Alvarez, C., & Favari, L. (2003). Silymarin increases antioxidant enzymes in alloxan-induced diabetes in rat pancreas. Comparative Biochemistry and Physiology. Toxicology & Pharmacology, 136(3), 205–212. https://doi.org/10.1016/s1532-0456(03)00214-x
Strain J. J. (1991). Disturbances of micronutrient and antioxidant status in diabetes. The Proceedings of the Nutrition Society, 50(3), 591–604. https://doi.org/10.1079/pns19910073
Strand, N., Anderson, M. A., Attanti, S., Gill, B., Wie, C., Dawodu, A., Pagan-Rosado, R., Harbell, M. W., & Maloney, J. A. (2024). Diabetic Neuropathy: Pathophysiology Review. Current Pain and Headache Reports, 28(6), 481–487. https://doi.org/10.1007/s11916-024-01243-5
Sultana, S., Munir, N., Mahmood, Z., Riaz, M., Akram, M., Rebezov, M., ... & Rengasamy, K. R. (2021). Molecular targets for the management of cancer using Curcuma longa Linn. phytoconstituents: A Review. Biomedicine & Pharmacotherapy, 135, 111078.
Sun, W., Mei, X., Wang, J., Mai, Z., & Xu, D. (2024). Zn(II)-curcumin prevents cadmium-aggravated diabetic nephropathy by regulating gut microbiota and zinc homeostasis. Frontiers in Pharmacology, 15, 1411230. https://doi.org/10.3389/fphar.2024.1411230
Suneja, M. (2021). Diabetic nephropathy and diabetic kidney disease. Journal of Diabetes Mellitus, 11(5), 359-377.
Suryanarayana, P., Satyanarayana, A., Balakrishna, N., Kumar, P. U., & Reddy, G. B. (2007). Effect of turmeric and curcumin on oxidative stress and antioxidant enzymes in streptozotocin-induced diabetic rat. Medical Science Monitor: International Medical Journal of Experimental and Clinical Research, 13(12), BR286–BR292.
Tabanelli, R., Brogi, S., & Calderone, V. (2021). Improving curcumin bioavailability: current strategies and future perspectives. Pharmaceutics, 13(10), 1715. https://doi.org/10.3390/pharmaceutics13101715
Thota, R. N., Acharya, S. H., & Garg, M. L. (2019). Curcumin and/or omega-3 polyunsaturated fatty acids supplementation reduces insulin resistance and blood lipids in individuals with high risk of type 2 diabetes: a randomised controlled trial. Lipids in Health and Disease, 18(1), 31. https://doi.org/10.1186/s12944-019-0967-x
Tomic, D., Shaw, J. E., & Magliano, D. J. (2022). The burden and risks of emerging complications of diabetes mellitus. Nature Reviews. Endocrinology, 18(9), 525–539. https://doi.org/10.1038/s41574-022-00690-7
Trujillo, J., Chirino, Y. I., Molina-Jijón, E., Andérica-Romero, A. C., Tapia, E., & Pedraza-Chaverrí, J. (2013). Renoprotective effect of the antioxidant curcumin: Recent findings. Redox Biology, 1(1), 448–456. https://doi.org/10.1016/j.redox.2013.09.003
Tu, Q., Li, Y., Jin, J., Jiang, X., Ren, Y., & He, Q. (2019). Curcumin alleviates diabetic nephropathy via inhibiting podocyte mesenchymal transdifferentiation and inducing autophagy in rats and MPC5 cells. Pharmaceutical Biology, 57(1), 778–786. https://doi.org/10.1080/13880209.2019.1688843
Tundis, R., Loizzo, M. R., Nabavi, S. M., Orhan, I. E., Skalicka-Wozniak, K., D’Onofrio, G., & Aiello, F. (2018). Natural compounds and their derivatives as multifunctional agents for the treatment of Alzheimer disease. In Discovery and Development of Neuroprotective Agents from Natural Products (pp. 63-102). Elsevier.
Ugo, C. H., Nnaemeka, M., Arene, E. C., Anyadike, I. K., Opara, S. O., Eze, P. N., ... & Ohiri, Z. C. (2022). Nutritional composition, bioavailability, medicinal functions and uses of turmeric: a review. Sch Bull, 8(8), 248-60.
Vinik, A. I., Maser, R. E., Mitchell, B. D., & Freeman, R. (2003). Diabetic autonomic neuropathy. Diabetes Care, 26(5), 1553–1579. https://doi.org/10.2337/diacare.26.5.1553
Wan, T. T., Li, X. F., Sun, Y. M., Li, Y. B., & Su, Y. (2015). Recent advances in understanding the biochemical and molecular mechanism of diabetic retinopathy. Biomedicine & Pharmacotherapy, 74, 145–147. https://doi.org/10.1016/j.biopha.2015.08.002
Wang, L. L., Sun, Y., Huang, K., & Zheng, L. (2013). Curcumin, a potential therapeutic candidate for retinal diseases. Molecular Nutrition & Food Research, 57(9), 1557–1568. https://doi.org/10.1002/mnfr.201200718
Wei, D. Z., Li, D., Zheng, D. M., An, Z. N., Xing, X. J., Jiang, D. W., Mei, X. F., & Liu, C. (2021). Curcumin conjugated gold nanoclusters as perspective therapeutics for diabetic cardiomyopathy. Frontiers in Chemistry, 9, 763892. https://doi.org/10.3389/fchem.2021.763892
Wei, Z., Pinfang, K., Jing, Z., Zhuoya, Y., Shaohuan, Q., & Chao, S. (2023). Curcumin improves diabetic cardiomyopathy by inhibiting pyroptosis through AKT/Nrf2/ARE pathway. Mediators of Inflammation, 2023, 3906043. https://doi.org/10.1155/2023/3906043
Wei, Z., Shaohuan, Q., Pinfang, K., & Chao, S. (2022). Curcumin attenuates ferroptosis-induced myocardial injury in diabetic cardiomyopathy through the Nrf2 pathway. Cardiovascular Therapeutics, 3159717. https://doi.org/10.1155/2022/3159717
Wu, H., Kong, L., Tan, Y., Epstein, P. N., Zeng, J., Gu, J., Liang, G., Kong, M., Chen, X., Miao, L., & Cai, L. (2016). C66 ameliorates diabetic nephropathy in mice by both upregulating NRF2 function via increase in miR-200a and inhibiting miR-21. Diabetologia, 59(7), 1558–1568. https://doi.org/10.1007/s00125-016-3958-8
Wu, Y., Tang, L., & Chen, B. (2014). Oxidative stress: implications for the development of diabetic retinopathy and antioxidant therapeutic perspectives. Oxidative Medicine and Cellular Longevity, 2014, 752387. https://doi.org/10.1155/2014/752387
Xu, J., Cai, S., Zhao, J., Xu, K., Ji, H., Wu, C., ... & Wu, Y. (2021). Advances in the relationship between pyroptosis and diabetic neuropathy. Frontiers in Cell and Developmental Biology, 9, 753660.
Xu, Y., & Hao, W. (2024). Curcumin affects the progression of diabetic foot ulcers by regulating CRP protein. Journal of Biological Regulators and Homeostatic Agents, 38(1), 449-458. 10.23812/j.biol.regul.homeost.agents.20243801.37
Yang, F., Yu, J., Ke, F., Lan, M., Li, D., Tan, K., Ling, J., Wang, Y., Wu, K., & Li, D. (2018). Curcumin alleviates diabetic retinopathy in experimental diabetic rats. Ophthalmic Research, 60(1), 43–54. https://doi.org/10.1159/000486574
Yang, Y., Duan, W., Liang, Z., Yi, W., Yan, J., Wang, N., Li, Y., Chen, W., Yu, S., Jin, Z., & Yi, D. (2013). Curcumin attenuates endothelial cell oxidative stress injury through Notch signaling inhibition. Cellular signalling, 25(3), 615–629. https://doi.org/10.1016/j.cellsig.2012.11.025
Yu, W., Wu, J., Cai, F., Xiang, J., Zha, W., Fan, D., Guo, S., Ming, Z., & Liu, C. (2012). Curcumin alleviates diabetic cardiomyopathy in experimental diabetic rats. PloS one, 7(12), e52013. https://doi.org/10.1371/journal.pone.0052013
Zakir, M., Ahuja, N., Surksha, M. A., Sachdev, R., Kalariya, Y., Nasir, M., ... & Mohamad, T. (2023). Cardiovascular complications of diabetes: from microvascular to macrovascular pathways. Cureus, 15(9), e45835. doi: 10.7759/cureus.45835
Zamanian, M. Y., Alsaab, H. O., Golmohammadi, M., Yumashev, A., Jabba, A. M., Abid, M. K., Joshi, A., Alawadi, A. H., Jafer, N. S., Kianifar, F., & Obakiro, S. B. (2024). NF-κB pathway as a molecular target for curcumin in diabetes mellitus treatment: Focusing on oxidative stress and inflammation. Cell Biochemistry and Function, 42(4), e4030. https://doi.org/10.1002/cbf.4030
Zhang, P., Fang, J., Zhang, J., Ding, S., & Gan, D. (2020). Curcumin inhibited podocyte cell apoptosis and accelerated cell autophagy in diabetic nephropathy via regulating Beclin1/UVRAG/Bcl2. Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy, 13, 641–652. https://doi.org/10.2147/DMSO.S237451
Zhang, W. X., Lin, Z. Q., Sun, A. L., Shi, Y. Y., Hong, Q. X., & Zhao, G. F. (2022). Curcumin ameliorates the experimental diabetic peripheral neuropathy through promotion of NGF expression in rats. Chemistry & Biodiversity, 19(6), e202200029. https://doi.org/10.1002/cbdv.202200029
Zhao, M., Wang, Y., Li, L., Liu, S., Wang, C., Yuan, Y., Yang, G., Chen, Y., Cheng, J., Lu, Y., & Liu, J. (2021). Mitochondrial ROS promote mitochondrial dysfunction and inflammation in ischemic acute kidney injury by disrupting TFAM-mediated mtDNA maintenance. Theranostics, 11(4), 1845-1863. https://doi.org/10.7150/thno.50905
Zhao, W. C., Zhang, B., Liao, M. J., Zhang, W. X., He, W. Y., Wang, H. B., & Yang, C. X. (2014). Curcumin ameliorated diabetic neuropathy partially by inhibition of NADPH oxidase mediating oxidative stress in the spinal cord. Neuroscience Letters, 560, 81–85. https://doi.org/10.1016/j.neulet.2013.12.019