Integrative Biomedical Research
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Integrative Biomedical Research
Integrative Biomedical Research is an, international, peer-reviewed, Open Access journal that publishes research articles on all aspects of biomedical, medicine, public health,
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Integrative Biomedical Research
Volume 9 Number 1 2025
Table of Contents
Research Article
Public Health
Md Samiul Bashir1*, Md. Abu Sayem 2, Shib Shankar Das3, Nishita Das4, Afrin Sultana5, Md. Moshiur Rahman6, Md Shamsuzzaman7, Pravas Paul8, Moazzam Hossian9, Md. Khaja Mohi Uddin 10
High viral load in HCC patients correlates with worsened liver function, systemic complications, and increased mortality, underscoring the need for early intervention.
Abstract | Full Text |PDF (688 KB) | Open Access Article
Cardiovascular Complications in Patients with Hepatocellular Carcinoma
Md. Khaja Mohi Uddin1, Afrin Sultana 2, Md. Moshiur Rahman3, Md Shamsuzzaman4, Pravas Paul 5, Md Mahmudul Hasan 6, Md. Abu Sayem 7, Md Samiul Bashir 8*, Shib Shankar Das 9, Moazzam Hossian 10
The study seeks to develop an HCC risk profile framework for clinicians to identify patients who may be at risk.
Abstract | Full Text |PDF (409 KB) | Open Access Article
Reviews
Public Health
An Insight into the Role of Artificial Intelligence in the Early Diagnosis of Alzheimer’s Disease
K M Sadat Samin1*, Soraya Sadek2
AI improves diagnosis, treatment planning, and patient outcomes by enabling early, accurate Alzheimer's disease identification using sophisticated data analysis.
Abstract | Full Text |PDF (347 KB) | Open Access Article
Machine Learning for Cardiovascular Healthcare: Opportunities, Challenges, and the Path Forward
Bayazid Hossain 1, Tanveer Ehsan Chowdhury 2, MD. Amir Hossain Fahad 3, Md. Emran Hossen 4, Rafiu Ahmed 5, Aolatun Nesa 6, Mahi Nur 7, Fuad Mohammad Rafiq 8, Md. Abu Sufian 9, Nasrullah Masud 10, Nafis Tasnim Turjo 11, Atiqur Rahman Sunny 12*
Machine learning improves healthcare efficiency; yet issues such as data privacy and bias must be resolved for ethical, scalable, and effective application.
Abstract | Full Text |PDF (257 KB) | Open Access Article
Tareq Ali Suliman Alsalloom 1*, Abdulmalik Hmoud Alsuwayh 1, Khaled Mesfer B. Alsubaie 1, Mohammed Abdullah M. Altuwayjiri 1, Omar Wuqayyan O. Al Luhayan 1, Faisal Mubarak Mutani Al-Harbi 1, Sultan Radhi S. Alanazi 1, Farhan Aldowy A. Alanazi 1, Mohammed Salim A. Al Shalawi 1, Talal Alhumidi F. Alharbi 1, Mohammed Hamad Almutairi 1, Yousef Salman Alsubhi 1, Abdullah Mukhlef J. Alanazi 1, Abdullah Ghazi Al Suqmi Alruwaili 1
Integrating food waste reduction with nutrition in public institutions fosters health equity, sustainability, and effective resource stewardship through evidence-based interventions.
Abstract | Full Text |PDF (310 KB) | Open Access Article
Mohamed F. H. Alsharari 1*, Marzouq F. S. Alrashdi 1, Fawaz A. G. Alsharari 1, Salem M. Salem 1, Saeed A. S. Al-Shahrani 1, Faisal N. S. Alshammari 1, Shimah A. T. Alrowaily 1, Adel Zaidan Masoud Al-Johani 1, Salem Mesfer Salem Alqahtani 1, Hatim Abdullah Alshehri 1, Aous Almarzooq 1
Integrating first aid education into higher learning cultivates health-literate, responsible graduates capable of enhancing campus safety and community resilience.
Abstract | Full Text |PDF (305 KB) | Open Access Article
Bandar Awadh M Almutairi 1, Fahad Farej F Alshammari 1, Abdulrahman Abdulmohsen Salh Alyousef 1, Tariq Mohammed Ruwayshid Alrehaili 1, Ali Abdullah Ali Al Shehri 2, Mohammed Saeed Saleh Al Qahtani 1, Sultan Obaid Salem Alharbi 1, Abdullah Sabih Alanazi 1, Rashed Nasser Salem Aldawsari 1, Munawir Zinaf M Alqahtani 3, Majed Malfi Salem Al-Harbi 3*
This review highlights how modern molecular diagnostics enhance early detection, guide clinical decisions, and strengthen global infectious disease surveillance and response systems.
Abstract | Full Text |PDF (293 KB) | Open Access Article
Masoud Aedh Alqahtani 1*, Ali Mushabbab Alshahrani 1, Ahmed Mohammed Haqawi 1, Waleed Abdullah Alghamdi 1, Abdullah Ali Bin Jabr 1, Abdullah Mohammed Ghaythan Alqarni 1, Khalid Nasser K Alqahtani 1, Ghadyan Salem Alshammari 1, Muteb Freeh Saleman Alshammari 1, Moteb Rshid Aswi Alshamarimo 1, Sultan Faris Rasheed Alshammari 1, Sharif Owaidh T. Almutairi 1, Hamad Khalid Saleh Alfunayyikh 1, Tareq Ali Suliman Alsalloom 1, Abdulmalik Hmoud Alsuwayh 1, Khaled Mesfer B Alsubaie 1
This review analyzes how ultra-processed foods elevate NCD risks and emphasizes urgent regulatory, educational, and policy measures for global health equity.
Abstract | Full Text |PDF (312 KB) | Open Access Article
Understanding Infectious Diseases: Prevention, Management, and Emerging Challenges
Badr Rashd Alrashedi 1*, Sari Mabrook Alrasheedi 1, Eman Smair Alanazi 1, Fatmah Malfi Altalouhi 1, Samar Saad Alotaibi 1, Tariq Mohammed Ruwayshid Alrehaili 1, Fahad Farej F. Alshammari 1, Badr Rashd Alrashedi 1, Abdullah Saleh Alshowmer 1, Abdullah Sabih Alanazi 1, Hamad Wazi Mulhi Alqahtani 1, Meshaal Ibrahim Al Owais 1, Adel Awadh Alrasheedi 1, Naser Algareesh 1, Sultan Khalifah Mabruk Almutairi 1, Mohammed Saeed Saleh Al Qahtani 1
This study provides a comprehensive understanding of infectious diseases, emphasizing prevention, early detection, and strategies to reduce global health burdens.
Abstract | Full Text |PDF (427 KB) | Open Access Article
The peer-reviewed and edited version of record published online before inclusion in an issue
These articles have been peer reviewed and accepted for publication. They are still in production and have not been edited, so may differ from the final published form.
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Advanced Dissolution Testing for Novel Drug Formulations: Challenges, Emerging Methods, and Regulatory Perspectives
This study enhances drug release evaluation and improves therapeutic outcomes using advanced dissolution testing techniques.
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Advancements in Virus Detection and Isolation: The Role of Chromatography in Virology Research and Health
This review discusses the viral infections, transmission, and morphology for developing effective diagnostics, treatments, and preventive strategies against future pandemics.
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Analysis of Potential Biomarkers in Hypertension
Biomarker-driven hypertension diagnostics enhance early detection, predict complications, and support precision medicine strategies to reduce global cardiovascular disease burden.
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Impact of Hemodiafiltration and Hemodialysis on FGF-23 Levels and Cardiovascular Calcification in End-Stage Renal Disease
This study determines the effects of dialysis modalities on FGF-23 levels and cardiovascular calcification, offering insights into improving ESRD patient outcomes.
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Predicting Habitat Suitability and Climate Change Impact on Medicinal plant Dalbergia latifolia and Dillenia pentagyna Using Ecological Niche Modelling
This study models current and future habitats, highlighting climate-driven distribution shifts and guiding conservation strategies for two economically valuable medicinal plants.
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Antioxidant Potential of Curculigo pilosa Rhizome Extracts in Hydrogen Peroxide Induced Oxidation In Vivo
Curculigo pilosa extracts exhibit strong antioxidant properties, mitigating oxidative stress in Drosophila melanogaster, highlighting potential therapeutic applications.
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A Comparative Analysis of Bioavailability and Stability of Anti-Diabetic Drugs in Conventional vs. Nanoparticle-Based Formulations – A Review
The study underscores nanoparticles' potential to improve stability, bioavailability, and therapeutic efficacy of anti-diabetic drugs versus conventional formulations.
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Effects of Physical Activity as A Treatment For Depression in the Elderly
Identifying effective physical activities for elderly depression supports holistic, low-cost, evidence-based interventions that enhance mental health and healthy aging.
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Collaborative Governance in Combating Illegal Cosmetics: A Study of Multi-Stakeholder Dynamics in South Sulawesi, Indonesia
This study evaluates collaborative governance in South Sulawesi to address illegal cosmetics, enhancing public health, regulatory compliance, and stakeholder coordination.
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Strategic Impurity Control in Next-Generation Pharmaceuticals: Analytical Technologies, Toxicological Assessment, and Regulatory Integration
Effective impurity control safeguards patient safety while accelerating pharmaceutical innovation and regulatory approval.
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Smart Nutrition and Active Living in Hypertension Management: Assessing Lifestyle Behaviors, Barriers, and the Role of Digital Health Tools
This study is significant as it highlights the effectiveness of smart nutrition and active living in managing hypertension, promoting sustainable, non-pharmacological interventions for better cardiovascular health.
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High Viral Load is a Risk Factor for Hepatocellular Carcinoma: Clinical and Laboratory Insights from a Cross-Sectional Study
High viral load in HCC patients correlates with worsened liver function, systemic complications, and increased mortality, underscoring the need for early intervention.
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Synergistic Effects of Cinnamomum zeylanicum and Atorvastatin in streptozotocin-Induced In Vivo
This study assesses the combined effects of Cinnamomum zeylanicum and atorvastatin on glucose regulation, lipid metabolism, and organ function in diabetic models.
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PEGylated Liposomal Teriflunomide: A Novel Approach of Targeted Breast Cancer Treatment to Advance Efficacy and Minimize Adverse Effects
Developing pegylated liposomal teriflunomide may enhance breast cancer treatment efficacy, reduce side effects, and improve patient outcomes.
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Comparative Effects of Sodium Dodecyl Sulfate and Hydrogen Peroxide on Type I and III Collagen Preservation in Decellularized Bovine Pericardium Scaffolds
SDS significantly reduces type I and III collagen density in decellularized bovine pericardium, whereas H2O2 better preserves extracellular matrix integrity.
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Cardiovascular Complications in Patients with Hepatocellular Carcinoma
The study seeks to develop an HCC risk profile framework for clinicians to identify patients who may be at risk.
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Multidisciplinary Challenges in Managing a Ruptured Ascending Aortic Aneurysm with Concurrent Pulmonary Pathology: A Case Report
This case highlights the challenges of managing ruptured aortic aneurysms with comorbidities, emphasizing multidisciplinary care and TEVAR’s limitations in complex cases.
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The Importance of Autoimmunity and Chronic Inflammation in the Development of Atherosclerosis: New Treatment Strategies
Understanding immune mechanisms in atherosclerosis enables development of targeted anti-inflammatory therapies, improving cardiovascular outcomes and plaque stabilization strategies.
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Early Surgical Intervention in Congenital Pulmonary Airway Malformation: A Case Report
Early recognition and surgical intervention in symptomatic CPAM cases prevent complications, ensuring optimal respiratory function and long-term clinical outcomes in neonates.
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The Evolving Role of Hospital and Community Pharmacist in Post-COVID-19 Healthcare Delivery in Bangladesh: A Survey-Based Analysis
This study highlights post-pandemic roles of Bangladeshi pharmacists, emphasizing their evolving contributions to healthcare access, management, and therapeutic decision-making.
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Global Burden, Risk Factors, and Evidence-Based Strategies for Cardiovascular Disease Prevention: A Comprehensive Systematic Review
This review highlights global CVD disparities, identifies major risk factors, and evaluates effective, cost-efficient prevention strategies for population health.
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AI-driven Innovations in Cancer Research and Personalized Healthcare
This study demonstrated the potential of AI to revolutionize cancer care through improved diagnostics, personalized treatment, and ethical implementation.
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Bacteriological Profile of Bacteremia and Antibiotic Resistance Patterns of the Isolated Pathogens
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Antidiabetic and Toxicological Evaluation of Ostodes Pauciflora merr. Seed (kop nut) Oil, A Potential Functional Food Alternative
This study evaluates Ostodes pauciflora Merr. seed oil for antidiabetic properties, providing insights into its potential as a functional food alternative.
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Synthesis, Characterization, and Antioxidant Potential of Nickel (II) Phthalocyanine for Industrial and Biomedical Applications
This study determined Nickel (II) phthalocyanine's antioxidant efficacy, structural characterization, and versatile applications in industry and therapeutic advancements.
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An Insight into the Role of Artificial Intelligence in the Early Diagnosis of Alzheimer’s Disease
AI improves diagnosis, treatment planning, and patient outcomes by enabling early, accurate Alzheimer's disease identification using sophisticated data analysis.
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Cardiometabolic Impact of Vitamin D Deficiency as a Determinant of Coronary Artery Disease: A Review
The results demonstrate a strong link between vitamin D deficiency and an increased risk of coronary heart disease in adults.
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Potential Therapeutic Targets Associated with the Autoimmune Response in Crohn's Disease
This review elucidates autoimmune mechanisms in Crohn’s disease, highlighting emerging molecular targets to advance precision immunotherapy and improve patient outcomes.
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Deep Mapping of Neuro-phenotypes Using AI-Enhanced MRI: A Contrast-Based Multiplanar Analysis
AI-driven contrast mapping enhances voxel-level T2-MRI brain analysis, revealing phenotypic variations crucial for early diagnosis and neurodevelopmental profiling
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TGF-β1 as a Molecular Target and Vitamin D Interaction in Diabetic Nephropathy: A Bio-clinical Correlation Study
Clarifies the potential role of vitamin D and kidney dysfunction in diabetic nephropathy through clinical and molecular analysis.
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Revolutionizing Healthcare: The Role of Artificial Intelligence in Drug Discovery and Delivery
This study shows how AI can change the way drugs are made and delivered, making healthcare faster, more personalized, and cheaper.
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Integrating Molecular Modeling and Kinetic Insights to Decipher Structure–Activity Relationship Trends in Small-Molecule Inhibitors of α-Glycosidases
This study clarifies structural features driving potent α-glycosidase inhibition, enabling rational design of selective therapeutics through integrated computational–experimental mechanistic insights.
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Multichemical Endocrine Disruption of Thyroid and Sex Hormone Signaling Drives Early-Life Neurodevelopmental Impairments
This study highlights how prenatal endocrine disruptor exposure impairs neurodevelopment, emphasizing mixture effects, biological mechanisms, and urgent regulatory intervention needs.