Latest Issue - Volume 9 Number 1 2025
Integrative Biomedical Research
Integrative Biomedical Research is an, international, peer-reviewed, Open Access journal that publishes research articles on all aspects of biomedical, medicine, public health,
Integrative Biomedical Research
Volume 9 Number 1 2025
Table of Contents
Research Article
Natural Drug Development
Md. Shakil Ahmed1, Saima Jahan Oishe1, Farhana Rahman1, Rabeya Basri1, Mahbuba Haque1, Mirza Nipa Monalisa1, Nishat Rayhana1, Shamima Ahsan1, Shangita Dev1, Md. Atiqur Rahman1*
This study documents plant diversity, cultural significance, and regional ethnomedicinal similarities, promoting sustainable traditional knowledge preservation and pharmacological research.
Abstract | Full Text |PDF (850 KB) |Supplementary Material | Open Access Article
Bacteriophage Therapy for Staphylococcus aureus Induced Postoperative Acute Endophthalmitis In Vivo
Muhammad Indra Mahardika Iridika Humeri1, Ismi Zuhria2, Rozalina Loebis2*, Wimbo Sasono2, Lukisiari Agustini2, Diah Indriani4, Firman Setiawan5, Annise Proboningrat6, Djoko Legowo6
This study determined the bacteriophage therapy's potential in reducing inflammation and preserving retinal structure post-cataract surgery-induced endophthalmitis.
Abstract | Full Text |PDF (678 KB) | Open Access Article
Antifungal Efficacy of Garlic and Olive Oil Against Candida albicans and Penicillium palitans
Amani Alhejely 1*
The study demonstrates the potential of garlic and olive oil as natural antifungal agents in managing fungal infections.
Abstract | Full Text |PDF (169 KB) | Open Access Article
Antifungal Properties of Dracaena cinnabari Resin Extracts Against Candida albicans
Rola Ali-Saeed1*, Aied M. Alabsi2, Siti Sufiah Shaherah binti Zainudin1, Nur Nadhirah binti Harun1, Lee Min Quan1, Siddig Ibrahim abdelwahab3, Antony V Samrot 4, Vetriselvan Subramaniyan5, Ismail, Muhamad Fareez6
This study determined Dracaena cinnabari's resin as a promising natural antifungal agent against Candida albicans, particularly in oral candidiasis.
Abstract | Full Text |PDF (369 KB) | Open Access Article
Mohd Hasan Mujahid 1, Tarun Kumar Upadhyay 1*, Vijay Jagdish Upadhye 2*, Prasanna Sriram Mathad 3
This study determined the therapeutic potential of Aqueous Zingiber officinale rhizome extract (AZOME) in combating oxidative stress, microbial infections, diabetes, and glycation-related complications.
Abstract | Full Text |PDF (2 MB) |Supplementary Material | Open Access Article
Antibacterial Activity of Sidr (Ziziphus spina-christi) Plant Extracts against Urinary Pathogens
Amal Naif Alshammari 1*
Sidr plant extracts showed promising antibacterial activity against urinary pathogens as potential alternative of UTI treatments.
Abstract | Full Text |PDF (211 KB) | Open Access Article
Advancing Therapeutic Efficacy of Star Anise Oil with (Illicium verum) Nano-Emulsion Formulation
Sharad Visht 1, Sana Sirwan Salih 1, Belan Azad Ibrahim 1, Daniah Issa Ismael 1, Serwa Falah Abdalwaheed 1, Omji Porwal 1
Star anise oil-based nano-emulsions' extraction, purification, and formulation processes to improve therapeutic efficacy of drug substances
Abstract | Full Text |PDF (1 MB) | Open Access Article
Haryoto1*, Alysa Vivi Arnida1, Peni Indrayudha1, Cita Hanif Muflihah1, Khong Heng Yen2
Mareme and Sala leaves mix may be a strong blood sugar blocker, but it contains useful chemicals for potential medical research.
Abstract | Full Text |PDF (318 KB) | Open Access Article
Investigation Of Anti-Tumour Activity Of Orthosiphon Stamineus On Human Oral Squamous Cell Carcinoma
Shah kamal Bin Jamal Dina, Fouad Saleih Resq Al-Suedeb,c*,Farahnaz Aminid, Aman Shah Abdul Majide, JackTan Chun Keatd, Amin Malik Shah Abdul Majidf .
The potential of Nuvastatic in the treatment of oral squamous cell carcinoma.
Abstract | Full Text |PDF (602 KB) | Open Access Article
Prakash Dabadi1, Fouad Saleih Resq AL-Suede2,3*, Chandrashekhar VM4*, Mallappa Shalavadi 4 , Ashok Gnanasekaran5
Development of therapeutics for the treatment of hepatotoxicity and oxidative stress induced by ATDs
Abstract | Full Text |PDF (589 KB) | Open Access Article
Ashwaq Hamid Salem Yehyaa,*, Majed Ahmed Al-Mansoubb, Fouad Saleih Resq Al-Suedea, Siti Balkees Binti STN Hameed Sultana, Muhammad Asyraf Abduramana, Noor Amanina Azmic, Mufda jameel abedalhadi alrawashdehd, Seyedeh Fatemeh Jafarie, Amin Malik Shah Abdul Majida,f
Abstract | Full Text |PDF (1015 KB) | Open Access Article
Evaluation on Antibacterial Activity and Hepatoprotectivity of Rauwolfia serpentina
Gnanasekaran Ashok1,6*, Yukshna A/P Ramunaidu2, Fouad saleih R.AL-Suede3,4 Murugesan Karthikeyan1, Pugazhandhi Bakthavatchalam5, Sajeewa P. Rathnayake6
The results of this study provide scientific evaluation of antibacterial activity and hepatoprotective effect of Rauwolfia serpentina which will be useful to researchers investigating the compounds with this potential and encouraging the development of new findings in this field.
Abstract | Full Text |PDF (556 KB) | Open Access Article
Aishath Thahuseen Waheed1, Thurga Ayavoo2,3, Karthikeyan Murugesan2,3, Fouad Saleih R. AL-Suede4,5, Ashok Gnanasekaran2,3*
Development of anti-inflammatory herbal drug.
Abstract | Full Text |PDF (464 KB) | Open Access Article
Ben Enoluomen Ehigiator1, SamuelKelechi Mobisson2, Iheanyichukwu Wopara3*, Chinonye Cynthia Chibuife1, Uwaezuoke Chukwuekele Awarajih3, Harrison Ogheneochuko Eruotor3
Abstract | Full Text |PDF (521 KB) | Open Access Article
Fouad Saleih R. Al-Suede1*, Mohamed B. Khadeer Ahamed1, Aman S. Abdul Majid2 Sultan Ayesh Mohammed Saghir3, Chern E. Oon4, Amin Malik Shah Abdul Majid1,5*
C5OSEW5050ESA OS strongly curbs variety of angiogenesis modulators in vitro, ex vivo and in vivo.
Abstract | Full Text |PDF (1 MB) | Open Access Article
Mansoureh Nazari Vishkaei a, Mohamed Khadeer Ahamed Basheer c, Amin Malik Shah Abdul Majid a,b
SLOS vesicles can be considered for effective dermal therapeutic agent for the treatment of skin cancer.
Abstract | Full Text |PDF (1 MB) | Open Access Article
Reviews
Natural Drug Development
Natural Polyphenol-Rich Inhibitors of Pancreatic Lipase for Obesity Management – A Systematic Review
Kamran Javed Naquvi 1*
This review discusses the plant-derived pancreatic lipase inhibitors as potential for natural, effective obesity management, reducing fat absorption and promoting metabolic health.
Abstract | Full Text |PDF (507 KB) | Open Access Article
Mechanisms and Future Perspectives of Curcumin in Diabetes Management
Kamran Javed Naquvi 1*
This review emphasizes curcumin's multifaceted roles in managing diabetes and its complications, highlighting the need for improved formulations to enhance efficacy.
Abstract | Full Text |PDF (570 KB) | Open Access Article
Rasmita Jena 1,2, Durga Madhab Kar 1*, Sovan Pattanaik 1, Bhisma Narayan Ratha 3
This review emphasizes the rich potential in traditional practices, offering valuable insights and solutions to current healing challenges.
Abstract | Full Text |PDF (934 KB) | Open Access Article
Moringa oleifera's Effect on Colorectal Cancer
Rolla Al-Shalabi 1,2, Nozlena abdul samad 1*, Lim Vuanghao 1, Ibrahim Al Deeb 2, Julia Joseph 1
The therapeutic benefit of Moringa plant in cancer treatment
Abstract | Full Text |PDF (2 MB) | Open Access Article
Efficacy of Herbal Medicine as Adjunctive Therapy for Skin Cancer
Norbayu Mansor1, Julia Joseph1, Rola Al Shalabi1, Nozlena Binti Abdul Samad*1
Phytochemicals can be used for skin cancer prevention and treatment.
Abstract | Full Text |PDF (373 KB) | Open Access Article
The peer-reviewed and edited version of record published online before inclusion in an issue
These articles have been peer reviewed and accepted for publication. They are still in production and have not been edited, so may differ from the final published form.
The Most Read ranking is based on the number of downloads in the last 60 days from papers published on the Journal of Angiotherapy within the last 12 months. Usage statistics are updated daily.
-
The Role of Quality Assurance in Accelerating Pharmaceutical Research and Development: Strategies for Ensuring Regulatory Compliance and Product Integrity
This study highlights the role of Quality Assurance in ensuring product integrity, patient safety, and driving pharmaceutical innovation.
-
Advanced Dissolution Testing for Novel Drug Formulations: Challenges, Emerging Methods, and Regulatory Perspectives
This study enhances drug release evaluation and improves therapeutic outcomes using advanced dissolution testing techniques.
-
Serum Albumin Levels as Predictors of Microvascular Health and Wound Healing Outcomes in Diabetic Foot Ulcers
This study deermines the critical role of serum albumin in improving vascularization and granulation tissue, reducing amputation risks in diabetic foot ulcers.
-
Knowledge in Enhancing Antenatal Care Compliance and Improving Maternal and Neonatal Health Outcomes
This study provides the understanding how knowledge influences antenatal care compliance can enhance health education strategies and improve maternal and neonatal health outcomes.
-
Prevalence and Risk Factors of Hypertension in Adolescents
This study determines hypertension prevalence and associated risk factors in Indonesian adolescents, crucial for targeted public health interventions.
-
Biogeochemical Role of Mangroves: Carbon Sequestration, Oxygen Release, and Their Contribution to Ecosystem Sustainability
This study highlights mangroves' critical role in carbon sequestration and oxygen release, contributing significantly to ecosystem and climate regulation.
-
Wastewater Treatment and Reuse: Preventive Measures for Chronic Infectious Diseases
This review discusses the significance of wastewater treatment in sustainability, water security, environmental preservation, human health safeguarding and resource recovery.
-
Advancements in Virus Detection and Isolation: The Role of Chromatography in Virology Research and Health
This review discusses the viral infections, transmission, and morphology for developing effective diagnostics, treatments, and preventive strategies against future pandemics.
-
Early Detection of Sickle Cell Anemia in Nilgiri Tribes Using a Hybrid Swin Transformer-Based RNN with Improved Weighted Quantum Monkey Optimization Algorithm Optimization
This model offers an accurate, timely SCA detection solution, improving healthcare outcomes for Nilgiri tribes and vulnerable populations.
-
Machine Learning in Healthcare: From Diagnostics to Personalized Medicine and Predictive Analytics
Machine learning transforms healthcare through accurate diagnosis, tailored therapies, and predictive analytics, promoting a future of precision medicine.
-
Sago and Katuk Leaf Combination Treatment Reduces The Blood Glucose Levels in Diabetes Mellitus Patients
This study demonstrates that sago and katuk leaves effectively reduce blood glucose levels, offering a cost-effective, culturally suitable diabetes management solution.
-
In Silico Determination of Tinospora cordifolia Phytochemicals as Potential DPP-4 Inhibitors for Type 2 Diabetes Management
This study determined Tinospora cordifolia phytochemicals as potential DPP-4 inhibitors, offering promising therapeutic candidates for type 2 diabetes.
-
A Cross-Sectional Study on Toxic Agents, Exposure Routes, and Healthcare Challenges on Pediatric Poisoning in the Al Jouf Region
This study emphasizes the need for preventive measures, caregiver education, and improved healthcare systems to reduce pediatric poisoning incidents.
-
Investigating the Impact of Tablet Coatings on Gastrointestinal Tract Residence Time and Drug Bioavailability: A Comparative Study of Different Coating Materials
This review discusses the importance of tailored tablet coatings to optimize drug release, stability, bioavailability, and therapeutic efficacy.
-
Lung-Targeted Solid Lipid Nanoparticles for Enhanced Pulmonary Delivery of Anti-Tubercular Drugs: A Novel Approach to Improve Bioavailability
Solid lipid nanoparticles improved anti-tubercular drug encapsulation, stability, and lung retention, offering a promising targeted pulmonary delivery approach for tuberculosis treatment.
-
Biological Maturity in Youth Athletes: Comparing Upper-Lower Body Ratios and Second Molar Eruption
Our study assesses upper-lower body ratios and second molar eruption as indicators of biological maturity in young athletes.
-
Antioxidant Potential of Curculigo pilosa Rhizome Extracts in Hydrogen Peroxide Induced Oxidation In Vivo
Curculigo pilosa extracts exhibit strong antioxidant properties, mitigating oxidative stress in Drosophila melanogaster, highlighting potential therapeutic applications.
-
Impact of Hemodiafiltration and Hemodialysis on FGF-23 Levels and Cardiovascular Calcification in End-Stage Renal Disease
This study determines the effects of dialysis modalities on FGF-23 levels and cardiovascular calcification, offering insights into improving ESRD patient outcomes.
-
Comparative Efficacy of Endovascular Versus Surgical Thrombectomy for Arteriovenous Graft Thrombosis in Hemodialysis Patients - A Systematic Review and Meta-Analysis
This study evaluates endovascular versus surgical thrombectomy in arteriovenous graft thrombosis, providing insights for optimizing hemodialysis vascular access management and patient outcomes.
-
Analysis of Potential Biomarkers in Hypertension
Biomarker-driven hypertension diagnostics enhance early detection, predict complications, and support precision medicine strategies to reduce global cardiovascular disease burden.
-
Hemoglobin N Seattle in a Bengali Child: Diagnostic Challenges and Insights into Genetic Diversity – A Case
This case highlights Hb N Seattle's first detection in a Bengali child, emphasizing diagnostic challenges and genetic diversity insights.
-
Factors Influencing Pulmonary Tuberculosis Incidence in Banggai Laut
This study identifies factors influencing TB distribution in Banggai Laut, offering insights for targeted interventions to improve public health outcomes.
-
Risk Factors for Knee Injuries in Sports and Intense Physical Exercise
This study highlights the importance of identifying risk factors for knee injuries to develop targeted prevention and rehabilitation strategies.
-
Predicting Habitat Suitability and Climate Change Impact on Medicinal plant Dalbergia latifolia and Dillenia pentagyna Using Ecological Niche Modelling
This study models current and future habitats, highlighting climate-driven distribution shifts and guiding conservation strategies for two economically valuable medicinal plants.
-
Exon 4 Mutations Determination in NOTCH3 Gene for Cryptogenic Ischemic Stroke
This study highlights the genetic and vascular risk factors for cryptogenic ischemic stroke in young adults, emphasizing prevention and personalized treatment strategies.
-
Collaborative Governance in Combating Illegal Cosmetics: A Study of Multi-Stakeholder Dynamics in South Sulawesi, Indonesia
This study evaluates collaborative governance in South Sulawesi to address illegal cosmetics, enhancing public health, regulatory compliance, and stakeholder coordination.
-
Advances in Human Umbilical Vein Scaffolds for Vascular Tissue Engineering: Innovations, Challenges, and Future Directions
This review explores innovative human umbilical vein scaffolds, enhancing vascular tissue engineering for regenerative medicine and cardiovascular applications.
-
A Review of Antipsychotic Medications on Hypercoagulability in Schizophrenia: Pathophysiology, Risks, and Management Strategies
Understanding antipsychotic-induced hypercoagulability in schizophrenia is crucial for reducing thromboembolic risks and improving patient outcomes.
-
Synergistic Effects of Cinnamomum zeylanicum and Atorvastatin in streptozotocin-Induced In Vivo
This study assesses the combined effects of Cinnamomum zeylanicum and atorvastatin on glucose regulation, lipid metabolism, and organ function in diabetic models.
-
Effects of Physical Activity as A Treatment For Depression in the Elderly
Identifying effective physical activities for elderly depression supports holistic, low-cost, evidence-based interventions that enhance mental health and healthy aging.
-
Smart Nutrition and Active Living in Hypertension Management: Assessing Lifestyle Behaviors, Barriers, and the Role of Digital Health Tools
This study is significant as it highlights the effectiveness of smart nutrition and active living in managing hypertension, promoting sustainable, non-pharmacological interventions for better cardiovascular health.
-
High Viral Load is a Risk Factor for Hepatocellular Carcinoma: Clinical and Laboratory Insights from a Cross-Sectional Study
High viral load in HCC patients correlates with worsened liver function, systemic complications, and increased mortality, underscoring the need for early intervention.
-
A Comparative Analysis of Bioavailability and Stability of Anti-Diabetic Drugs in Conventional vs. Nanoparticle-Based Formulations – A Review
The study underscores nanoparticles' potential to improve stability, bioavailability, and therapeutic efficacy of anti-diabetic drugs versus conventional formulations.
-
Phytochemical Composition, Antioxidant, and Anti-Inflammatory Activities of Laurus nobilis Leaf Extracts Using Solvent Fractionation
Ethyl acetate extract of Laurus nobilis leaves showed potent antioxidant and anti-inflammatory activities, highlighting its therapeutic and pharmacological potential.Pages: 1-8
-
Strategic Impurity Control in Next-Generation Pharmaceuticals: Analytical Technologies, Toxicological Assessment, and Regulatory Integration
Effective impurity control safeguards patient safety while accelerating pharmaceutical innovation and regulatory approval.
-
Comparative Effects of Sodium Dodecyl Sulfate and Hydrogen Peroxide on Type I and III Collagen Preservation in Decellularized Bovine Pericardium Scaffolds
SDS significantly reduces type I and III collagen density in decellularized bovine pericardium, whereas H2O2 better preserves extracellular matrix integrity.
-
Evaluation of Cardiac Biomarkers as Predictors of Short-Term Mortality Following Coronary Artery Bypass Grafting
This study evaluates the predictive value of biomarkers in short-term mortality after coronary artery bypass grafting to guide clinical decisions.
-
Machine Learning for Cardiovascular Healthcare: Opportunities, Challenges, and the Path Forward
Machine learning improves healthcare efficiency; yet issues such as data privacy and bias must be resolved for ethical, scalable, and effective application.
-
PEGylated Liposomal Teriflunomide: A Novel Approach of Targeted Breast Cancer Treatment to Advance Efficacy and Minimize Adverse Effects
Developing pegylated liposomal teriflunomide may enhance breast cancer treatment efficacy, reduce side effects, and improve patient outcomes.
-
Enhancing Pharmacological Access and Health Outcomes in Rural Communities through Renewable Energy Integration: Implications for chronic inflammatory Disease Management
This study emphasises how renewable energy enhances pharmacological logistics, clinical service continuity, and health outcomes in rural, disadvantaged healthcare systems.
-
Multidisciplinary Challenges in Managing a Ruptured Ascending Aortic Aneurysm with Concurrent Pulmonary Pathology: A Case Report
This case highlights the challenges of managing ruptured aortic aneurysms with comorbidities, emphasizing multidisciplinary care and TEVAR’s limitations in complex cases.
-
The Importance of Autoimmunity and Chronic Inflammation in the Development of Atherosclerosis: New Treatment Strategies
Understanding immune mechanisms in atherosclerosis enables development of targeted anti-inflammatory therapies, improving cardiovascular outcomes and plaque stabilization strategies.
-
Cardiovascular Complications in Patients with Hepatocellular Carcinoma
The study seeks to develop an HCC risk profile framework for clinicians to identify patients who may be at risk.
-
Potential Role of Helicobacter pylori Infection in Hepatocellular Carcinoma: A Clinical and Laboratory-Based Study
The study is to determine the pervasiveness of H. pylori infection among patients with liver illness of HCC.
-
Early Surgical Intervention in Congenital Pulmonary Airway Malformation: A Case Report
Early recognition and surgical intervention in symptomatic CPAM cases prevent complications, ensuring optimal respiratory function and long-term clinical outcomes in neonates.
-
The Evolving Role of Hospital and Community Pharmacist in Post-COVID-19 Healthcare Delivery in Bangladesh: A Survey-Based Analysis
This study highlights post-pandemic roles of Bangladeshi pharmacists, emphasizing their evolving contributions to healthcare access, management, and therapeutic decision-making.
-
Integrating Health Analytics tools to Enhance Pharmacological Management and Patient Outcomes in Hospital Settings
This study emphasises that the integration of business and HR analytics improves hospital efficiency, personnel management, and patient care outcomes.
-
OR-PSGAN-CNN: An Occlusion-Robust Deep Learning Framework for Early Detection of Cerebral Palsy in Infants Using RGB-D Videos
Improves early cerebral palsy detection by resolving pose occlusions through enhanced skeleton generation and feature extraction from infant movement videos.
-
Bacteriological Profile of Bacteremia and Antibiotic Resistance Patterns of the Isolated Pathogens
-
Antidiabetic and Toxicological Evaluation of Ostodes Pauciflora merr. Seed (kop nut) Oil, A Potential Functional Food Alternative
This study evaluates Ostodes pauciflora Merr. seed oil for antidiabetic properties, providing insights into its potential as a functional food alternative.
-
AI-driven Innovations in Cancer Research and Personalized Healthcare
This study demonstrated the potential of AI to revolutionize cancer care through improved diagnostics, personalized treatment, and ethical implementation.
-
Synthesis, Characterization, and Antioxidant Potential of Nickel (II) Phthalocyanine for Industrial and Biomedical Applications
This study determined Nickel (II) phthalocyanine's antioxidant efficacy, structural characterization, and versatile applications in industry and therapeutic advancements.
-
Global Burden, Risk Factors, and Evidence-Based Strategies for Cardiovascular Disease Prevention: A Comprehensive Systematic Review
This review highlights global CVD disparities, identifies major risk factors, and evaluates effective, cost-efficient prevention strategies for population health.
-
An Insight into the Role of Artificial Intelligence in the Early Diagnosis of Alzheimer’s Disease
AI improves diagnosis, treatment planning, and patient outcomes by enabling early, accurate Alzheimer's disease identification using sophisticated data analysis.
-
Cardiometabolic Impact of Vitamin D Deficiency as a Determinant of Coronary Artery Disease: A Review
The results demonstrate a strong link between vitamin D deficiency and an increased risk of coronary heart disease in adults.
-
Potential Therapeutic Targets Associated with the Autoimmune Response in Crohn's Disease
This review elucidates autoimmune mechanisms in Crohn’s disease, highlighting emerging molecular targets to advance precision immunotherapy and improve patient outcomes.
-
TGF-β1 as a Molecular Target and Vitamin D Interaction in Diabetic Nephropathy: A Bio-clinical Correlation Study
Clarifies the potential role of vitamin D and kidney dysfunction in diabetic nephropathy through clinical and molecular analysis.
-
Synergistic Effects of Cinnamomum zeylanicum and Atorvastatin in streptozotocin-Induced In Vivo
This study assesses the combined effects of Cinnamomum zeylanicum and atorvastatin on glucose regulation, lipid metabolism, and organ function in diabetic models.
Submit Article
Use the online submission system to send us your manuscript.
Call for Papers
We are seeking Contributions for a special issue. More.
Best Paper Award
Authors are awarded for Best Paper for this Journal Annually
Advertisement