Angiogenesis, Inflammation & Therapeutics | Online ISSN  2207-872X
RESEARCH ARTICLE   (Open Access)

Factors Influencing Childhood Vaccine Refusal in Parents in Southern Malaysia and Its Effect on Health: A Cross-sectional Study

Sakina Ruhi 1*, Adlina Abdullatif 1, Jegathambigai R. Naidu 1, Hana Chen 1, Ayesha Syed 1, Danish Saud khan 2, Husni Ahmed Al Gosha 1, Sohayla Mohamed Elsherbini A 1, Mya Mya Thwin 1, Thin Thin Aung 1

+ Author Affiliations

Journal of Angiotherapy 8(2) 1-9 https://doi.org/10.25163/angiotherapy.829475

Submitted: 01 January 2024  Revised: 19 February 2024  Published: 22 February 2024 

Abstract

Background: Recent increases in the number of communicable disease cases in Malaysia have caused significant concern, particularly as vaccine hesitancy remains  a significant challenge. This study aimed to explore parents' knowledge, perceptions, and factors associated with childhood vaccine refusal in order to have better understanding about vaccine hesitancy. Method: This study utilized an online cross- sectional questionnaire distributed via snowball sampling to parents in Melaka and Johor. 369 respondents completed the survey. Result: The results showed significant differences between religion against parents' perceptions and knowledge (p<0.001 and p=0.015) and between parents' knowledge and perception and vaccine refusal factors (p<0.001, both). Other than that, there are significant association between education level and parent's perception regarding vaccine. The positive perception surrounding vaccine is the major cause of vaccine refusal which contradictwith previous study. Conclusion: The study's conclusion was that parental perception in the South region of Malaysia is affected by religious restrictions and education level, while parents' perception about vaccines is more likely to cause vaccine refusal in children. Therefore, it is essential to educate parents about the efficacy of vaccines in protecting their children and to address concerns related to religious beliefs. Overall, this study sheds light on the important role that education and awareness play in overcoming vaccine hesitancy in Malaysia. By understanding parents' knowledge and perceptions, public health officials can develop targeted interventions to increase vaccine uptake and improve the overall health of the population.

Keywords: Parent’s perception; vaccination; immunization; Melaka; Johor

References

 

 

 

 

 

 

 

Abdullah, A. (2023). Vaccine Hesitancy Among Parents in Johor Bahru: A Qualitative Study. Journal of Public Health and Epidemiology, 15(2), 45-52.

Ahmed, A., Lee, K. S., Bukhsh, A., Al-Worafi, Y. M., Sarker, M. M. R., Ming, L. C., & Khan, T. M. (2018). Outbreak of vaccine-preventable diseases in Muslim majority countries. Journal of infection and public health, 11(2), 153–155. https://doi.org/10.1016/j.jiph.2017.09.007

Anjum, Q., Omair, A., Inam, S. N., Ahmed, Y., Usman, Y., & Shaikh, S. (2004). Improving vaccination status of children under five through health education. JPMA. The Journal of the Pakistan Medical Association, 54(12), 610– 613

Awadh, A. I., Hassali, M. A., Al-lela, O. Q., Bux, S. H., Elkalmi, R. M., & Hadi, H. (2014). ¿Una intervención educativa mejora el conocimiento de los padres sobre la inmunización? Experiencia de Malasia. BMC Pediatrics, 14(1), 1–7. Retrieved from https://bmcpediatr.biomedcentral.com/track/pdf/10.1186/1471- 2431-14-254

Birmingham, W.C.; Macintosh, J.L.B.; Vaughn, A.A.; Graff, T.C. (2019). Strength of Belief: Religious Commitment, Knowledge, and HPV Vaccination Adherence. Psychooncology, 28(1227–1233).

Centers for Disease Control and Prevention. (2021, September 1). Immunization Basics | CDC. Retrieved October 20, 2022, from https://www.cdc.gov/vaccines/vac-gen/imzbasics.htm

Chaudhary, N., Weissman, D., & Whitehead, K. A. (2021). mRNA vaccines for infectious diseases: principles, delivery and clinical translation. Nature Reviews Drug Discovery, 20(11), 817–838. https://doi.org/10.1038/s41573-021-00283-5

Coast Peninsular Malaysia. Malaysian Journal of Medicine and Health Sciences, 17(1), 2636–9346.

Cooper, S., Schmidt, B.-M., Sambala, E. Z., Swartz, A., Colvin, C. J., Leon, N., & Wiysonge, C. S. (2021). Factors that influence parents' and informal caregivers' views and practices regarding routine childhood vaccination: a qualitative evidence synthesis. https://doi.org/10.1002/14651858.CD013265.pub2

Creighton, A. R. (2016). Gaba Binggi (Good Needles): Developing an understanding of how two Aboriginal communities see and experience immunisation during pregnancy (Doctoral dissertation).

De Albuquerque Veloso Machado, M., Roberts, B., Wong, B. L. H., van Kessel, R., & Mossialos, E. (2021). The relationship between the COVID-19 pandemic and vaccine hesitancy: a scoping review of literature until August 2021. Frontiers in public health, 9

Elkalmi, R. M., Dyab, E., Suhaimi, A. M., Blebil, A. Q., Elnaem, M. H., Jamshed, S., & Gajdács, M. (2021). Attitude, familiarity and religious beliefs about vaccination among health science and non-health science students in a Malaysian public university. European Journal of Investigation in Health, Psychology and Education, 11(4), 1462–1473. https://doi.org/10.3390/ejihpe11040104

Frenkel, L. D. (2021, September). The global burden of vaccine-preventable infectious diseases in children less than 5 years of age:Implications for COVID-19 vaccination.How can we do better?. In Allergy and Asthma Proceedings (Vol. 42, No. 5, pp. 378-385). OceanSide Publications, Inc.

Health Security Agency, U. (2022). Vaccines and porcine gelatine. Retrieved from www.healthpublications.gov.uk/Home.html

HHS, CDC, & Oid. (2011). A CDC FRAMEWORK FOR PREVENTING INFECTIOUS DISEASES Sustaining the Essentials and Innovating for the Future.

Ibrahim, S., & Lee, C. Y. (2021). Understanding Cultural and Religious Influences on Vaccine Refusal: A Study in Southern Malaysia. Asian Journal of Social Science, 49(3), 321-335.

Ismail, Z. (2022, May 31). Childhood Immunisation in Malaysia: The Past, the Present & the Future - Positive Parenting. Retrieved October 20, 2022, from https://mypositiveparenting.org/2022/05/31/childhood-immunisation-in-malaysia-thepast-the-present-the-future/

Jansen, K., Kirman, J., Xing, Z., Offit, P. A., Geoghegan, S., & O’callaghan, K. P. (2019). Vaccine Safety: Myths and Misinformation. https://doi.org/10.3389/fmicb.2020.00372

Khoo, Y. S. K., Ghani, A. A., Navamukundan, A. A., Jahis, R., & Gamil, A. (2019). Unique product quality considerations in vaccine development, registration and new program implementation in Malaysia. https://doi.org/10.1080/21645515.2019.1667206

Khoo, Y. S. K., Ghani, A. A., Navamukundan, A. A., Jahis, R., & Gamil, A. (2019). Unique product quality considerations in vaccine development, registration and new program implementation in Malaysia. https://doi.org/10.1080/21645515.2019.1667206

Krishna, D., Mohd Zulkefli, N.A., Md Said, S. et al. Sociodemographic and health care factors in determining immunization defaulters among preschool children in Petaling District, Selangor: a cross-sectional study in Malaysia. BMC Public Health, 19(1275), https://doi.org/10.1186/s12889-019-7561-z

Kyprianidou, M., Tzira, E., Galanis, P., & Giannakou, K. (2021). Knowledge of mothers regarding children's vaccinations in Cyprus: A cross-sectional study. PloS one, 16(9), e0257590. https://doi.org/10.1371/journal.pone.0257590

Lee, J. K. F., & Leow, P. L. (2012, April 27). Introduction of Immunisation - PORTAL MyHEALTH. Retrieved October 20, 2022, from http://www.myhealth.gov.my/en/introduction-of-immunisation-2/

Lim, W. Y., Amar-Singh, H. S. S., Jeganathan, N., Rahmat, H., Mustafa, N. A., Mohd Yusof, F.-S., … N-Julia, M. S. (2016). Exploring immunisation refusal by parents in the Malaysian context. Cogent Medicine, 3(1), 1142410. https://doi.org/10.1080/2331205x.2016.1142410

Liu, Y., Ma, Q., Liu, H., & Guo, Z. (2022). Public attitudes and influencing factors toward COVID-19 vaccination for adolescents/children: a scoping review. Public Health, 205, 169-181.

Matta, P., El Mouallem, R., Akel, M., Hallit, S., & Fadous Khalife, M. C. (2020). Parents' knowledge, attitude and practice towards children's vaccination in Lebanon: role of the parent-physician communication. BMC Public Health, 20(1), 1439. https://doi.org/10.1186/s12889-020-09526-3

Meng, Y. C. (2020, April 25). Malaysia sees drop in measles cases | The Star.Retrieved from https://www.thestar.com.my/news/nation/2020/04/25/malaysia-sees-drop-in- measlescases
 

Mora, T., & Trapero-Bertran, M. (2018). The influence of education on the access to childhood immunization: The case of Spain. BMC Public Health, 18(1), 1–9. https://doi.org/10.1186/s12889-018-5810-1

Ota, M. O. C., de Moraes, J. C., Vojtek, I., Constenla, D., Doherty, T. M., Cintra, O., & Kirigia, J. M. (2022). Unveiling the contributions of immunization for progressing towards Universal Health Coverage. Human Vaccines and Immunotherapeutics, 18(1). https://doi.org/10.1080/21645515.2022.2036048

Rahim, N. A., & Tan, S. H. (2022). Factors Contributing to Vaccine Refusal in Southern Malaysia: A Case-Control Study. Malaysian Journal of Community Health, 18(1), 77-84.

Ruhi, S., Nabilah, P., Attalla, S. M., Treki, M., Khan, J., Ishaka, A., ... & Hasan, S. (2021). Understanding the Negative Public Perception on Vaccination in West Coast and East Coast Peninsular Malaysia. Malaysian Journal of Medicine & Health Sciences, 17(1).

Statistica Research Department. (2022, October 5). Malaysia: DPT immunization of children 2019. Statista. Retrieved October 11, 2022, from https://www.statista.com/statistics/733421/malaysia-dpt-immunization-of children/

Tengku Muhammad Fakhruddin, T. M. F., Aminnuddin, M., & Shafei, M. N. (2023). Knowledge of the Malaysian National Immunisation Programme and its associated factors among parents in Dungun, Terengganu: A cross-sectional study. Malaysian family physician: the official journal of the Academy of Family Physicians of Malaysia, 18, 3. https://doi.org/10.51866/oa.188

Voo, J. Y. H., Lean, Q. Y., Ming, L. C., Hanafiah, N. H. M., Al-Worafi, Y. M., & Ibrahim, B. (2021). Vaccine knowledge, awareness and hesitancy: A cross sectional survey among parents residing at Sandakan district, Sabah. Vaccines, 9(11), 1–12. https://doi.org/10.3390/vaccines9111348

Wong, L. P., Wong, P. F., & AbuBakar, S. (2020). Vaccine hesitancy and the resurgence of vaccine preventable diseases: The way forward for Malaysia, a Southeast Asian country. Human Vaccines and Immunotherapeutics, 16(7), 1511–1520. https://doi.org/10.1080/21645515.2019.1706935

World Health Organization. (2019). Measles - Rubella, Bulletin, 13(1).

World Health Organization. (2021, August 30). Vaccines and immunization: What is vaccination? Retrieved October 11, 2022, from https://www.who.int/newsroom/questions-and-answers/item/vaccines-and-immunization-what-is-vaccination

Yeong, M. L. (2015, November 25). Immunisation: Facts And Myths - PORTAL MyHEALTH. Retrieved October 20, 2022, from http://www.myhealth.gov.my/en/immunisation-factsmyths/

Zingg, A., & Siegrist, M. (2012). Measuring people’s knowledge about vaccination: Developing a one-dimensional scale. Vaccine, 30(25), 3771–3777. https://doi.org/10.1016/j.vaccine.2012.03.014

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