Bioinfo Chem

System biology and Infochemistry
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Bioinfo Chem

Latest Issue - Volume 7 Number 1 2025

Bioinfo Chem

Bioinfo Chem

Descriptive Table of Contents


Research Article

Bioinformatics & In Silico Modeling

Research Article | Bioinformatics & In Silico Modeling Published online 10 October 2025

Computational Elucidation of EGCG Interaction with PD-L1: A Natural Strategy for Immune Checkpoint Modulation in Melanoma

Shahadat Hossain1*, Moin Uddin Patwary2, Md Abdus Samad3, Hossen Md. Arafat4

pp. 1-11
Views: 193 | Downloads: 0

Epigallocatechin gallate (EGCG) offers a safe, natural alternative to antibody therapies by directly targeting PD-L1 and modulating immune response pathways.

Abstract | Full Text |PDF (982 KB) | Open Access Article

  

Computational Pharmacology

Research Article | Computational Pharmacology Published online 25 September 2025

Virtual Screening and Computational Analysis of Natural Compound Targeting CDK4/6 for Pan-Cancer Therapeutic Potential

Shahadat Hossain1*, Farhana Ferdushi Aion2, Badhan Mojumder2

pp. 1-10
Views: 137 | Downloads: 0

This study identifies Luteolin as a potential multi-target CDK4/6 inhibitor with broader anti-cancer action than current synthetic drugs.

Abstract | Full Text |PDF (692 KB) | Open Access Article

  

Structural Biology / Molecular Docking

Research Article | Structural Biology / Molecular Docking Published online 28 August 2025

Targeting Mutant KRAS G12C with Berberine Derivatives: A Molecular Docking and Dynamics Approach in Colorectal Cancer

Shahadat Hossain1*, Md. Taufique Hasan Bhuiyan Sezan2, Moin Uddin Patwary3

pp. 1-11
Views: 150 | Downloads: 0

Berberine offers a natural, safe, and multi-pathway alternative for selectively targeting KRAS G12C in colorectal cancer therapy development.

Abstract | Full Text |PDF (523 KB) | Open Access Article

  

Research Article | Structural Biology / Molecular Docking Published online 27 January 2025

Computational Repurposing of Flavokawain B as a Novel p38 MAPK Inhibitor for Triple-Negative Breast Cancer Therapy

Abdullah Bhuyan1*, Shahadat Hossain2, Moin Uddin Patwary1, Shamim Al Mamun1, Tanjila Hasan Tulon1

pp. 1-11
Views: 260 | Downloads: 2

Flavokawain B’s inhibition of MAPK14 suggests its potential as a novel, natural therapeutic candidate against TNBC progression.

Abstract | Full Text |PDF (992 KB) | Open Access Article