Journal of Angiotherapy
Angiogenesis, Inflammation & Therapeutics | Online ISSN  2207-872X
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RESEARCH ARTICLE   (Open Access)
Contents Vol 8 (8)

Safety and Efficacy of Tubeless Percutaneous Nephrolithotomy: A Prospective Randomized Study

Mohamed Zewita 1*, Mahmoud M. Shalaby 2, Atef M. Abdlatif 2, M. Atef Abdalziz 2

+ Author Affiliations

Journal of Angiotherapy 8 (8) 1-7 https://doi.org/10.25163/angiotherapy.889771

Submitted: 29 May 2024 Revised: 26 June 2024  Published: 02 August 2024 

Abstract

Background: Urinary lithiasis, or kidney stone disease, is a common and longstanding health issue characterized by significant morbidity and recurrence. Despite advancements in treatment modalities, managing large or complex renal stones continues to pose challenges. The evolution of surgical techniques, such as percutaneous nephrolithotomy (PCNL), has significantly impacted the management of kidney stones. This study aims to evaluate the safety and efficacy of tubeless PCNL compared to conventional PCNL in patients with renal and upper ureteric stones. Methods: A prospective randomized study was conducted at the Urology and Nephrology University Hospital, Assiut University, Egypt, from September 2016 to September 2019. The study included 60 patients who met the inclusion criteria and were randomly assigned into two groups: Group 1 (conventional PCNL) and Group 2 (tubeless PCNL). Postoperative outcomes, including pain scores, fever, blood loss, urinary leakage, length of hospitalization, need for re-hospitalization, and stone-free rates, were evaluated. Statistical analyses were performed using SPSS version 20.0, with a p-value of less than 0.05 considered statistically significant. Results: A total of 60 patients were included in the final analysis, equally divided into two groups. There were no statistically significant differences between the groups regarding demographic data, stone characteristics, hemoglobin levels, creatinine levels, or blood loss. However, the duration of surgery was significantly longer in the tubeless group (Group 2) compared to the conventional group (Group 1) (P-value = 0.034). Both groups achieved comparable stone-free rates with no significant differences in postoperative complications. Conclusion: Tubeless PCNL is a safe and effective alternative to conventional PCNL for managing renal and ureteral stones, with comparable outcomes in terms of blood loss, creatinine, and hemoglobin levels. The main advantage of tubeless PCNL is the potential for reduced postoperative discomfort and quicker recovery, although it requires a longer operative time. These findings support the use of tubeless PCNL as a viable option in appropriately selected patients, with implications for improving patient outcomes and reducing healthcare costs associated with kidney stone management.

Keywords: Tubeless Percutaneous Nephrolithotomy (PCNL), Renal stones, Postoperative outcomes, Surgical techniques, Kidney stone management

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