Journal of Angiotherapy
Angiogenesis, Inflammation & Therapeutics | Online ISSN  2207-872X
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RESEARCH ARTICLE   (Open Access)
Contents Vol 8 (8)

Impact of Anadara granosa L. and Spirulina platensis on Sperm Morphology and Motility in Mus musculus

Netty Ino Ischak 1*, Loso Judijanto 2, Eddyman W Ferial 3

+ Author Affiliations

Journal of Angiotherapy 8 (8) 1-7 https://doi.org/10.25163/angiotherapy.889934

Submitted: 03 June 2024 Revised: 09 August 2024  Published: 12 August 2024 

Abstract

Background: Infertility, characterized by the inability to conceive, affects both men and women equally, with male infertility often linked to factors such as sperm quality and hormonal imbalances. Nutrition plays a significant role in spermatogenesis, with zinc (Zn) being crucial for sperm development. This study explored the effects of combining Anadara granosa L. (blood cockles) and Spirulina platensis on sperm morphology and motility in Mus musculus mice. Methods: Thirty male mice were divided into six treatment groups, with varying proportions of blood cockles and Spirulina platensis. Treatments were administered for 21 days, and sperm samples were collected from the cauda epididymis for morphological and motility analysis. Data were statistically analyzed using ANOVA and Kruskal-Wallis tests. Results: After 21 days, groups treated with a combination of Anadara granosa L. and Spirulina platensis showed improved sperm motility, with the group receiving a 50% mixture demonstrating the highest motility (89%). Morphological analysis revealed no significant alterations across treatment groups, though zinc (Zn) contributed to enhanced sperm quality by facilitating spermatogenesis and improving metabolic functions in sperm cells. Conclusion: The combination of Anadara granosa L. and Spirulina platensis significantly improved sperm motility, primarily due to the high zinc content. However, morphology remained unaffected, suggesting the treatment's potential as a dietary intervention for male infertility linked to motility deficiencies. Further studies are recommended to explore long-term impacts and optimal dosing.

Keywords: Anadara granosa, Spirulina platensis, Sperm motility, Sperm morphology, Preclinical testing

References

Ardakani, Mohammad A., Shapour H., Rasoul S., Norouz D., & Hassan M. (2018). Antioxidant Effects of Spirulina platensis (Arthrospira platensis) on Cyclophosphamide-Induced Testicular Injury in Rats. Jurnal Veterinary Research Forum, 9(1), 35-41.

Andry, J., Tannady, H., Dwinoor Rembulan, G., & Freggy Dinata, D. (2023). Analysis of the Omicron virus cases using data mining methods in rapid miner applications. Microbes and Infectious Diseases, 4(2), 323-334. doi: 10.21608/mid.2023.194619.1469

Delfita, Rina. (2014). Antifertility Potential of Black Tea Extract in Male Mus musculus L. Mice. Jurnal Sainstek, 6(2), 181-188.

Dewi, S.E., Eddiwan, & Efawani. (2018). Morphometrics and Growth Patterns of Blood Clams (Anadara granosa) in the Waters of Bagan Siapi-Api, Rokan Hilir Regency. Jurnal Berkala Perikanan Terubuk, 46(3), 37-45.

El-Hakim, Y.M.A., Wafaa A.M, & Abeer E.E. (2018). Spirulina platensis Attenuates Furan Reprotoxicity by Regulating OxidativeStress, Inflammation, and Apoptosis in Testis of Rats. Jurnal Ecotoxicology and Environmental Safety, 16(1), 25-33.

Farag, M.R., R.M. Abd El-Aziz, H.A. Ali, & Sahar, A.A. (2015). Evaluating the Ameliorative Efficacy of Spirulina platensis on Spermatogenesis and Steroidogenesis in Cadmium-Intoxicated Rats. Jurnal Environ Sci Pollut Res. DOI 10.1007/s11356-015-5314-9.

Intan, Afrizal T., & Irvina N. (2014). Blood Clam (Anadara granosa) Abundance in Coastal Water of Tanjung Balai AsahanNorth Sumatera. Jurnal Ilmu Kelautan dan Perikanan, 1(1), 1-9.

Iriandini, J., Lydia T. dan Benny W. (2023). The Effect of Light Application on Sperm of Male Mice Mus musculus. Jurnal e-Biomedik, 1(1), 420-426.

Kartika, A.A., H.C.H. Siregar, & A.M.Fuah. (2013). Strategy for Developing Rat (Rattus norvegicus) and Mice (Mus musculus) Livestock Business at the Faculty of Animal Husbandry, IPB. Jurnal Ilmu Produksi dan Teknologi Hasil Pangan, 1(3), 147-154.

Khalil, M. (2016). Bioecology of the Bivalve Genus Anadara (Bivalvia: Archidae). Sefa Bumi Persada: Medan.

Lindawaty, Irma D., & Sofyatuddin K. (2016). Distribution and Density of Blood Clams (Anadara sp.) Based on Substrate Texture in UleeLheue Waters, Banda Aceh. Jurnal Ilmiah Mahasiswa Kelautan dan Perikanan Unsyiah, 1(1), 114-123.

Madyatmadja, E. D., Marvell, M., Andry, J. F., Tannady, H., & Chakir, A. (2021). Implementation of Big Data in Hospital using Cluster Analytics. International Conference on Information Management and Technology (ICIMTech), Jakarta, Indonesia, 496-500, doi: 10.1109/ICIMTech53080.2021.9535015.

Madyatmadja, E. D., Rianto, A., Andry, J. F., Tannady, H., & Chakir, A. (2021). Analysis of Big Data in Healthcare Using Decision Tree Algorithm. 1st International Conference on Computer Science and Artificial Intelligence (ICCSAI), Jakarta, Indonesia, 313-317, doi: 10.1109/ICCSAI53272.2021.9609734.

Nirmalasari, R. (2017). The Effect of Providing Anadara Granosa L. Blood Clam Nutrition on Sperm Density Levels of Mus Musculus L. Mice. Jurnal Biologi Makassar, 2(1), 9-14.

Payaran, K.O., Benny W., & Lydia T. (2014). The Effect of Zinc Administration on Sperm Quality in Male Mice (Mus Musculus). Jurnal e- Biomedik, 2(2), 496-500.

Sugiantari, Ida Ayu P., Ida Bagus Made S, & Ni Made Rai S. (2020). Sperm Concentration and Thickness of Seminiferous Tubules of Male White Rats After Giving Moringa Leaf (Moringa oleifera L.) Brew. Jurnal Metamorfosa, 7(2), 240-247.

Heryadi, D.Y., Tannady, H., Rembulan, G.D., Rofatin, B., & Sundari, R.S. (2023). Changes in behavior and welfare of organic rice farmers during the COVID-19 pandemic. Caspian Journal of Environmental Sciences, 21(1), 191–197.

Tungadi, R., Abdulkadir, W., & Ischak, N. I., & Rahim, B. R. (2019). Liposomal Formulation of Snakehead Fish (Ophiocephalus striatus) Powder and Toxicity Study in Zebrafish (Danio rerio) Model. Pharmaceutical Sciences, 25(2), 145-153.

Zainuddin, Nyoman P.S., & Trijoko. (2018). Diversity of the Genus Anadara Based on Morphological Characters and Habitat in Coastal Waters, Tarakan City, North Kalimantan. Jurnal Trop Biodiv-Biotech, 3(1), 26-29.

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