Early Diagnosis and Management of Neonatal Acute Hematogenous Osteomyelitis: A Case Report
Sushma1, Nandipatti2, Mary Chandrika3, Aljin V*4
Journal of Angiotherapy 6(1) 1-4 https://doi.org/10.25163/angiotherapy.61621782922221222
Submitted: 29 November 2021 Revised: 12 November 2021 Published: 05 January 2022
Abstract
Background: Neonatal acute hematogenous osteomyelitis (NAHO) is a rare yet severe condition caused by bacterial infection of bone and marrow due to hematogenous spread. This case report details a 21-day-old male neonate diagnosed with NAHO of the left distal femur. The infant presented with knee swelling and restricted movement of the left lower extremity, but lacked fever or systemic symptoms, complicating diagnosis. Diagnostic imaging and blood cultures confirmed Staphylococcus aureus as the pathogen. Treatment with intravenous Ceftriaxone sodium for three weeks led to significant clinical improvement and complete recovery. Method: The diagnosis was established through a combination of imaging studies (X-ray, CT, MRI), which revealed bone destruction, periosteal reaction, and abnormal cartilage signal intensity. Blood cultures confirmed Staphylococcus aureus. The patient was treated with intravenous Ceftriaxone sodium for three weeks, with regular follow-up and assessments to monitor clinical response and recovery. Conclusion: Early diagnosis and aggressive antibiotic therapy are crucial in managing NAHO to prevent serious complications such as chronic osteomyelitis and growth disturbances. This case emphasizes the importance of high clinical suspicion, comprehensive imaging, and timely microbiological studies. The positive outcome underscores the effectiveness of early intervention and highlights the need for heightened awareness among clinicians dealing with neonates presenting with subtle infection signs.
Keywords: Neonatal osteomyelitis, Staphylococcus aureus, Ceftriaxone therapy, Diagnostic imaging, Early intervention.
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