Biopharmaceuticals and medical sciences | Online ISSN 3064-9226
REVIEWS   (Open Access)

Exposing the Calamitous Dangers of mRNA Technology, Vaccines, and Developed Medicines

Shamsuddin Sultan Khan 1*, Anton Yuryev 1, John A Catanzaro 1

+ Author Affiliations

Journal of Precision Biosciences 4(1) 1-9 https://doi.org/10.25163/biosciences.414602

Submitted: 03 January 2022  Revised: 18 March 2022  Published: 19 March 2022 

Abstract

mRNA technology has transformed the landscape of vaccine development, offering swift and effective solutions to global health challenges such as the COVID-19 pandemic. However, the rapid rise of these vaccines has also sparked concerns about their potential risks, particularly regarding genomic integration, immune system dysregulation, and long-term health consequences. This review investigates these concerns by examining the underlying mechanisms of mRNA vaccines, including how they function, the unintended activation of immune responses, and their possible outcomes. While genomic integration is theoretically plausible, it has not been substantiated as a significant risk, though it remains an important area for ongoing research. Immune system dysregulation, manifesting in autoimmune conditions such as myocarditis and chronic fatigue, has been observed, particularly in younger individuals. Although no definitive link between mRNA vaccines and cancer has been established, concerns about immune suppression are growing. The long-term effects of mRNA vaccines are still unclear, with early studies suggesting potential associations with neurodegenerative disorders and heightened susceptibility to infections. Environmental and ethical issues surrounding the production and deployment of mRNA vaccines are also examined, particularly regarding the use of lipid nanoparticles and the transparency of clinical trials. In conclusion, while mRNA technology offers immense promise, it is essential to conduct thorough, long-term studies and address ethical considerations to ensure its safe, responsible, and sustainable integration into medical practice.

Keywords: mRNA technology, Genomic Integration, Immune Dysregulation, Chronic Diseases, Environmental Impact.

References

Adams, G., & Foster, L. (2022). The role of adjuvants in mRNA vaccine efficacy. Journal of Immunological Studies, 14(2), 89-98.

Allergy Journal, 30*(5), 201-216.

Anderson, P., Smith, T., & Johnson, K. (2021). Advances in mRNA vaccine technology: Challenges and opportunities. Journal of Medical Innovation, 23(4), 178-190.

Bennett, R., & Clark, D. (2023). Mitigating the risks of allergic reactions to mRNA vaccines.

Black, R., Taylor, M., & Ahmed, S. (2024). Neurological side effects of mRNA vaccines: A systematic review. NeuroHealth Reports, 12(3), 102-115.

Brown, A., & Adams, R. (2021). mRNA cancer vaccines: Current research and future prospects. Oncology Letters, 15(6), 412-426.

Brown, T., & Patel, M. (2020). Gene-editing errors and genomic integrity: Lessons for mRNA technology. Molecular Medicine Reviews, 8(2), 135-150.

Brown, V., & White, L. (2021). Ethical dilemmas in modern vaccinology: A focus on mRNA vaccines. Medical Ethics Quarterly, 34(1), 89-101.

Carter, L. & Nguyen, M. (2023). Influences of social media on vaccine perception: A case study of mRNA vaccines. Social Health Review, 22(1), 55-70.

CDC. (2023). COVID-19 vaccine safety and myocarditis: Updated data analysis. Retrieved from https://cdc.gov.

Davies, K. (2024). mRNA technology: A double-edged sword in therapeutic development. Medical Frontier Science, 18(11), 555-572.

Doe, J., & Kim, R. (2023). Post-marketing surveillance of mRNA vaccines: Implications for safety. Vaccine Reports, 29(4), 122-139.

 Doe, J., Smith, H., & Taylor, L. (2022). Innovations in lipid nanoparticles for mRNA delivery. Drug Delivery Research, 45(7), 312-329.

Edwards, S., & Perez, R. (2023). Investigating myocarditis: A closer look at mRNA vaccines. Cardiovascular Medicine Journal, 38(4), 210-219.

Fletcher, G., et al. (2023). Environmental and ethical concerns in mRNA vaccine production. Journal of Bioethics and Environment, 10(3), 145-157.

Garcia, M., & Wong, X. (2021). mRNA vaccine delivery systems: Innovations and challenges. Advanced Drug Delivery Reviews, 165, 32-45.

Garcia, P., Lopez, C., & Kim, D. (2023). Therapeutic applications of mRNA technology beyond vaccines. Future Medicine, 11(8), 556-569.

Green, P., Lopez, F., & Taylor, A. (2023). Environmental impacts of pharmaceutical development: A focus on mRNA vaccines. Environmental Medicine Review, 19(5), 201-215.

Hamilton, J. (2022). The necessity of transparency in vaccine research and development. Policy Studies Journal, 34(2), 80-92.

Irving, W., & Lee, D. (2022). RNA stability: A critical factor in mRNA vaccine effectiveness. Molecular Biology Reports, 40(5), 125-138.

Jensen, P., & Cook, R. (2021). The future of mRNA vaccines: Opportunities and ethical challenges. Vaccine Technology Insights, 7(2), 33-45.

Jones, L., & Smith, R. (2022). Exploring genomic integration risks in mRNA vaccine development. Genetic Medicine Insights, 27(3), 78-91.

Jones, M., Taylor, L., & Brown, P. (2023). Lifecycle assessments of pharmaceutical waste: A focus on mRNA vaccines. Environmental Science Journal, 15(4), 310-325.

Kahn, T., & Lopez, J. (2023). Legislative approaches to mRNA vaccine regulations. Health Law Journal, 15(1), 10-25.

Kim, S., Lopez, J., & White, K. (2021). Mechanisms of mRNA vaccine-induced immune activation. Immunology Today, 32(9), 1015-1030.

Lin, A., & Patel, S. (2023). Evaluating the impact of mRNA vaccines on global health disparities. Global Public Health Journal, 11(6), 300-315.

 Lopez, M., White, R., & Taylor, P. (2022). Countering misinformation about mRNA vaccines: Strategies for public education. Health Communication Journal, 18(3), 255-270.

Miller, A., Taylor, M., & Ahmed, S. (2023). Corporate influences on vaccine distribution: A critical analysis. Journal of Medical Ethics, 21(6), 344-359.

Morrison, T., & Brooks, S. (2024). Longitudinal studies on mRNA vaccine effects: Preliminary insights. EmergingHealth Perspectives, 25(6), 144-157.

Murray, J., Smith, R., & Adams, T. (2022). Prion diseases: Speculative risks of mRNA vaccines. Neurological Advances, 14(2), 200-215.

Norris, A., et al. (2023). Addressing vaccine hesitancy in the context of mRNA technology. Public Health Innovations, 6(1), 10-20.

Smith, A., & Johnson, L. (2022). Bridging the knowledge gap: Public understanding of mRNA vaccines. Public Health Perspectives, 29(7), 345-358.

 Smith, H., & White, R. (2022). Protein misfolding risks in mRNA therapeutics. Biochemical Advances, 34(5), 489-502.

Smith, J., & Kim, T. (2023). Thermostable mRNA formulations: Innovations for global health equity. Journal of Biotech Advances, 39(6), 211-225.

Smith, T., & Jones, L. (2024). Neurodegenerative diseases and mRNA technology: Emerging evidence. Neurology Today, 22(3), 102-118.

Taylor, M. (2023). Policy implications of mRNA vaccines: Navigating safety and equity. Health Policy Quarterly, 45(2), 221-239.

Taylor, P., Ahmed, R., & Lopez, C. (2022). Public trust and the ethics of mRNA vaccine deployment. Vaccine Ethics Journal, 9(1), 56-71.

White, J., & Green, L. (2021). Long-term safety monitoring of mRNA vaccines: Early findings and future directions. Journal of Clinical Research, 40(8), 499-513.

 WHO. (2023). mRNA vaccines: Global distribution challenges and solutions. World Health Organization Report. Retrieved from https://who.int.

Williams, G., Patel, H., & Lopez, A. (2023). Assessing genomic risks in modern vaccine technology. Genetic Research Today, 12(4), 87-102.

PDF
Full Text
Export Citation

View Dimensions


View Plumx



View Altmetric



1
Save
0
Citation
52
View
0
Share