Data Modeling
Mathematical and Computational Data Modeling
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Controlling Outbreaks of Acute Contagious Conjunctivitis Infection: A Diagnostic Review and Proposal for Mobile-Based Screening
Kamruzzaman Mithu 1*
Data Modeling 1 (1) 1-14 https://doi.org/10.25163/data.1110859
Submitted: 09 September 2026 Revised: 01 November 2020 Accepted: 09 November 2020 Published: 11 November 2020
Abstract
Conjunctivitis is, in some ways, an unassuming diagnosis — red eyes, some discharge, a bit of grittiness — yet it turns out to be one of the more frequently encountered conditions across both primary care and ophthalmology settings worldwide, carrying a financial burden that is anything but small. This review set out, somewhat modestly, to pull together the existing evidence on how conjunctivitis is recognized, classified, and managed, with a particular eye toward the persistent difficulty of telling viral, bacterial, and allergic subtypes apart at the bedside. A structured literature search was conducted across three major databases using a focused set of keywords, restricted to publications from 2013 through early 2020, from which ten studies were ultimately retained for synthesis. What emerged was a fairly consistent picture of diagnostic uncertainty: clinical heuristics long treated as reliable — discharge type, reaction pattern, symptom timing — proved considerably less trustworthy than textbooks tend to suggest, and this ambiguity appears to feed directly into patterns of antibiotic overprescribing, particularly outside specialist care. At the same time, a smaller subset of findings pointed toward conjunctivitis occasionally serving as a visible marker of broader systemic disease, underscoring the value of a careful history even in seemingly routine cases. Building on these findings, this review also outlines a proposed smartphone-based screening tool intended to make earlier, more accessible triage possible, especially for populations with limited access to eye care. Taken together, the evidence suggests that improving diagnostic confidence — whether through better clinical training or emerging screening technology — may be one of the more practical levers available for reducing unnecessary treatment and limiting the spread of conjunctivitis outbreaks at a community level.
Keywords: conjunctivitis; pink eye; red eye; controlling outbreaks of conjunctivitis; spread control of pink eye; solutions for controlling conjunctivitis.
References
Bielory, B., & Bielory, L. (2010). Atopic dermatitis and keratoconjunctivitis. Immunology and Allergy Clinics of North America, 30(3), 323–336. https://doi.org/10.1016/j.iac.2010.06.004
Bielory, L., & Frohman, L. P. (1992). Allergic and immunologic disorders of the eye. Journal of Allergy and Clinical Immunology, 89(1), 1–15. https://doi.org/10.1016/S0091-6749(05)80033-8
de Laet, C., Dionisi-Vici, C., Leonard, J. V., McKiernan, P., Mitchell, G., Monti, L., Voit, T., Cochat, P., Roberts, N. B., Watson, A. R., Pintos-Morell, G., Santer, R., & Beauchamp, G. R. (2013). Recommendations for the management of tyrosinaemia type 1. Orphanet Journal of Rare Diseases, 8, Article 8. https://doi.org/10.1186/1750-1172-8-8
Everitt, H., & Little, P. (2002). How do GPs diagnose and manage acute infective conjunctivitis? A GP survey. Family Practice, 19(6), 658–660. https://doi.org/10.1093/fampra/19.6.658
Friedlaender, M. H. (2011). Ocular allergy. Current Opinion in Allergy and Clinical Immunology, 11(5), 477–482. https://doi.org/10.1097/ACI.0b013e32834a9652
La Rosa, M., Lionetti, E., Reibaldi, M., Russo, A., Longo, A., Leonardi, S., Tomarchio, S., Avitabile, T., & Reibaldi, A. (2013). Allergic conjunctivitis: A comprehensive review of the literature. Italian Journal of Pediatrics, 39, Article 18. https://doi.org/10.1186/1824-7288-39-18
Narayana, S., & McGee, S. (2015). Bedside diagnosis of the 'red eye': A systematic review. American Journal of Medicine, 128(11), 1220–1224. https://doi.org/10.1016/j.amjmed.2015.06.026
Ryder, E. C., & Benson, S. (2020). Conjunctivitis. In StatPearls. StatPearls Publishing.
Sati, A., Sangwan, V. S., & Basu, S. (2013). Porphyria: Varied ocular manifestations and management. BMJ Case Reports, 2013, Article bcr2013009496. https://doi.org/10.1136/bcr-2013-009496
Shekhawat, N. S., Shtein, R. M., Blachley, T. S., & Stein, J. D. (2017). Antibiotic prescription fills for acute conjunctivitis among enrollees in a large United States managed care network. Ophthalmology, 124(8), 1099–1107. https://doi.org/10.1016/j.ophtha.2017.04.034
Smith, A. F., & Waycaster, C. (2009). Estimate of the direct and indirect annual cost of bacterial conjunctivitis in the United States. BMC Ophthalmology, 9, Article 13. https://doi.org/10.1186/1471-2415-9-13
Soparkar, C. N., Wilhelmus, K. R., Koch, D. D., Wallace, G. W., & Jones, D. B. (1997). Acute and chronic conjunctivitis due to over-the-counter ophthalmic decongestants. Archives of Ophthalmology, 115(1), 34–38. https://doi.org/10.1001/archopht.1997.01100150036004
van Ketel, W. G., & Melzer-van Riemsdijk, F. A. (1980). Conjunctivitis due to soft lens solutions. Contact Dermatitis, 6(5), 321–324. https://doi.org/10.1111/j.1600-0536.1980.tb04956.x
Wilson-Holt, N., & Dart, J. K. (1989). Thiomersal keratoconjunctivitis, frequency, clinical spectrum and diagnosis. Eye, 3, 581–587. https://doi.org/10.1038/eye.1989.91
Woodland, R. M., Darougar, S., Thaker, U., Cornell, L., Siddique, M., Wania, J., & Wania, S. (1992). Causes of conjunctivitis and keratoconjunctivitis in Karachi, Pakistan. Transactions of the Royal Society of Tropical Medicine and Hygiene, 86(3), 317–320. https://doi.org/10.1016/0035-9203(92)90328-A
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