Prevalence of Multi-drug Resistant (mdr) Pseudomonas sp. Among Patients Attending in Tertiary Care Hospital, Dhaka City, Bangladesh

S. M. Kamrul Islam ^1,2, Maruf Abony ², Aneeka Nawar Fatema ², Suvamoy Datta ^2*

Unchecked antibiotic use is causing Pseudomonas sp. to become more resistant. It's crucial to manage antibiotics responsibly to combat this.

Abstract

The resistance pattern of Pseudomonas sp. isolates in recent years is increasing very rapidly because of the uncontrolled, unsupervised, and unnecessary usage of antibiotics. Current study aims to evaluate the prevalence of multidrug-resistant (MDR) Pseudomonas sp. isolated from clinical samples collected from tertiary care hospitals in Dhaka, Bangladesh. In this study, a total of 1440 samples were collected from January 2019 to September 2019, followed by using conventional methods, as well as the Kirby-Bauer disc diffusion method for culture and susceptibility of Samples, respectively. Finally, Stata 14 software was utilized to analyze the obtained data. From among 1440 samples, 480 (33.3%) cases were bacteriologically positive. Imipenem (11%) showed the least resistance followed by Meropenem (20%), where Nalidixic acid exhibited the highest drug resistance. Additionally, 202 (48.08%) and 278 (57.92%) cases were identified as MDR and non-drug-resistance (NDR). The number of male MDR cases was higher than females. It is alarming to increase MDR pathogens. This bacterial resistance can be prevented through control measures that limit the spread of resistant bacteria and the regular monitoring of this resistance phenotype of pathogens, along with the rational use of antimicrobial therapy.

Keywords: Multidrug-resistant (MDR), Pseudomonas sp., Kirby-Bauer disc diffusion, Tertiary care hospital, and Dhaka city.

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