Individualized Immunotherapy Approaches in Precision Medicine

Md. Kamrul Hasan Chowdhury; Md Shamsuddin Sultan Khan

doi:10.25163/biosciences.310033

Biopharmaceuticals and medical sciences | Online ISSN 3064-9226

REVIEWS (Open Access)

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Individualized Immunotherapy Approaches in Precision Medicine

Md. Kamrul Hasan Chowdhury ¹, Md Shamsuddin Sultan Khan ²

+ Author Affiliations

Journal of Precision Biosciences 4 (1) 1-12 https://doi.org/10.25163/biosciences.310033

Submitted: 08 November 2021 Revised: 12 January 2021 Published: 11 January 2022

Abstract

In the field of precision medicine, individualized immunotherapy is a paradigm shift that provides customized therapeutic methods based on the unique immunological profiles of patients. This method acknowledges that each person’s immune response is unique and that treating complicated diseases—especially those involving cancer and autoimmune disorders—may not be best served by a one-size-fits-all approach. The search for biomarkers that can forecast a patient’s reaction to particular treatments is one of the main tenets of personalized immunotherapy. Clinicians can gain a more individualized understanding of how the immune system interacts with diseases by detecting molecular and genetic signatures within a patient’s immune system. By using this data, immunotherapies that are most likely to be beneficial for a certain patient are chosen, reducing the need for trial-and-error procedures and their possible side effects. Highly-throughput technology and recent developments in genetics have made personalized immunotherapy a viable option. The creation of tailored cancer vaccines has been made possible by the identification of neoantigens, tumor-specific antigens resulting from mutations, made possible by the effective analysis of vast datasets. Furthermore, the development of CRISPR gene-editing technology has made it possible to modify immune cells to improve their ability to target particular illnesses.In summary, tailored immunotherapy has the potential to completely transform precision medicine’s therapeutic approach. Realizing the full promise of individualized immunotherapies across multiple medical disciplines will depend on our ability to traverse the challenges of using the immune system for therapeutic reasons. This will require both technological advancements and a deeper understanding of individual immunological profiles.

Keywords: Cancer Vaccines,Biomarkers, Precision Medicine, Personalized Treatments.

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