Integrative Biomedical Research | Online ISSN  2207-872X
REVIEWS   (Open Access)

The Immune System-Boosting Effect of Vegetables: A Nutritional Viewpoint with a Focus on Paramedics Contributions

Abdulaziz Mohammed Almuhaylib 1*, Badr Sayyah Al-Anzi 1, Ahmed Ibrahim Al-Ahmad 1, Sultan Suleiman Issa Al-Harb 1, Sultan Mohammed Algfari 1, Nawaf Sakr Almutairi 1, Bader Talhab Al-Anzi 1, Abeer Ali Alyehya 1, Zaid Helal Alanaz 2, Mokhld Sanhat Alotaibi 2, Yousef Mansour Aloudah 2, Abdulrahman Munawir Alanazi 2, Rayid Mohammed Alanazi 2, Talal Fares Awadh Almutairi 2, Mohammed Farhan Aldhafiri 2, Mohammed Raja  Alharithi 2, Eman Sulaiman A Aljuaid 2, Alaa saud Alanazi 2*

+ Author Affiliations

Journal of Angiotherapy 8(6) 1-9 https://doi.org/10.25163/angiotherapy.8610192

Submitted: 16 April 2024  Revised: 10 June 2024  Published: 15 June 2024 

Paramedics can enhance immune health by promoting nutrition, detecting deficiencies, and collaborating with public health experts for better patient outcomes.

Abstract


The immune system plays an essential for keeping the body healthy and protecting it from dangerous infections. Nutrition is an important driver of immunological function, with vitamins and minerals serving as necessary cofactors for immune responses. Micronutrient deficiencies, such as those in vitamins A, B, C, D, E, zinc, selenium, and iron, may impair immune responses, making them more susceptible to infections and inflammatory diseases. Paramedics, as frontline healthcare workers, have the opportunity to bridge the gap between emergency treatment and preventive health efforts by teaching patients about healthy nutrition. They may encourage immune-boosting diets, detect nutritional deficiencies, and work with public health specialists to optimize patient outcomes. However, challenges including lack of resources, insufficient nutrition expertise, and time restrictions make it difficult for them to provide useful nutritional advice. Future initiatives should include incorporating nutrition teaching into paramedic training, strengthening relationships with nutritionists, and creating community-based nutrition programs. A holistic approach to immunological health that incorporates good diet and medicinal therapies may dramatically improve illness prevention and patient resilience. This study emphasizes the relevance of paramedics in nutritional health, recommending more participation in public health education and dietary treatments to improve immune function.

Keywords: Nutrition, vegetables, immunomodulators, micronutrients, immune system, paramedics, public health.

References


Ahmed, N., Escalona, R., Leung, D., Chan, E., & Kannourakis, G. (2018, December). Tumour microenvironment and metabolic plasticity in cancer and cancer stem cells: Perspectives on metabolic and immune regulatory signatures in chemoresistant ovarian cancer stem cells. In Seminars in Cancer Biology (Vol. 53, pp. 265–281). Academic Press.

Ashaolu, T. J. (2020). Immune boosting functional foods and their mechanisms: A critical evaluation of probiotics and prebiotics. Biomedicine & Pharmacotherapy, 130, 110625.

Bartolucci, S., & Piccirillo, C. A. (2017). Immune regulation in human health and disease. eLS, 2017, 1–17.

Belkaid, Y., & Hand, T. W. (2014). Role of the microbiota in immunity and inflammation. Cell, 157(1), 121–141.

Bell, A., Galligan, L., & Latham, J. (2020). Numeracy in paramedicine education: A literature review. Adults Learning Mathematics, 15(1), n1.

Cai, H., Chen, L., Yin, C., Liao, Y., Meng, X., Lu, C., Tang, S., Li, X., & Wang, X. (2020). The effect of micronutrients on malnutrition, immunity and therapeutic effect in patients with pulmonary tuberculosis: A systematic review and meta-analysis of randomized controlled trials. Tuberculosis, 125, 101994.

Carrillo, J. L. M., Rodríguez, F. P. C., Coronado, O. G., García, M. A. M., & Cordero, J. F. C. (2017). Physiology and pathology of innate immune response against pathogens. In Physiology and pathology of immunology. IntechOpen.

Cilla, A., Bosch, L., Barberá, R., & Alegría, A. (2018). Effect of processing on the bioaccessibility of bioactive compounds—A review focusing on carotenoids, minerals, ascorbic acid, tocopherols and polyphenols. Journal of Food Composition and Analysis, 68, 3–15.

Eaton, G., Tierney, S., Wong, G., Oke, J., Williams, V., & Mahtani, K. R. (2022). Understanding the roles and work of paramedics in primary care: A national cross-sectional survey. BMJ Open, 12(12), e067476.

Eaton, G., Wong, G., Tierney, S., Roberts, N., Williams, V., & Mahtani, K. R. (2021). Understanding the role of the paramedic in primary care: A realist review. BMC Medicine, 19, 1–14.

Eaton, G., Wong, G., Williams, V., Roberts, N., & Mahtani, K. R. (2020). Contribution of paramedics in primary and urgent care: A systematic review. British Journal of General Practice, 70(695), e421–e426.

Elmadfa, I., & Meyer, A. L. (2019). The role of the status of selected micronutrients in shaping the immune function. Endocrine, Metabolic & Immune Disorders - Drug Targets, 19(8), 1100–1115.

Ericsson, C. R., Lindström, V., Rudman, A., & Nordquist, H. (2022). Paramedics’ perceptions of job demands and resources in Finnish emergency medical services: A qualitative study. BMC Health Services Research, 22(1), 1469.

Garcia, M., Mamedova, L. K., Barton, B., & Bradford, B. J. (2018). Choline regulates the function of bovine immune cells and alters the mRNA abundance of enzymes and receptors involved in its metabolism in vitro. Frontiers in Immunology, 9, 2448.

Gombart, A. F., Pierre, A., & Maggini, S. (2020). A review of micronutrients and the immune system—working in harmony to reduce the risk of infection. Nutrients, 12(1), 236.

Heidt, S., Roelen, D. L., Eijsink, C., Eikmans, M., Van Kooten, C., Claas, F. H. J., & Mulder, A. (2010). Calcineurin inhibitors affect B cell antibody responses indirectly by interfering with T cell help. Clinical & Experimental Immunology, 159, 199–207.

Hoffmann, J., & Akira, S. (2013). Innate immunity. Current Opinion in Immunology, 25(1), 1–3.

Juhrmann, M. L., Vandersman, P., Butow, P. N., & Clayton, J. M. (2022). Paramedics delivering palliative and end-of-life care in community-based settings: A systematic integrative review with thematic synthesis. Palliative Medicine, 36(3), 405–421.

Krensky, A. M., Bennett, W. M., & Vincenti, F. (2010). Goodman and Gilman’s the pharmacological basis of therapeutics (7th ed.). McGraw-Hill.

London, C. (2010). Functional foods that boost the immune system. Functional Food Product Development, 2010, 293–321.

López-Pedrera, C., Villalba, J. M., Patiño-Trives, A. M., Luque-Tévar, M., Barbarroja, N., Aguirre, M. Á., Escudero-Contreras, A., & Pérez-Sánchez, C. (2021). Therapeutic potential and immunomodulatory role of coenzyme Q10 and its analogues in systemic autoimmune diseases. Antioxidants, 10(4), 600.

Luckheeram, R. V., Zhou, R., Verma, A. D., & Xia, B. (2012). CD4+ T cells: Differentiation and functions. Clinical and Developmental Immunology, 2012, 925135.

Luebke, R. W., & Germolec, D. R. (2010). The immune system. In Environmental impacts on reproductive health and fertility (pp. 188–193). Cambridge University Press.

Marshall, J. S., Warrington, R., Watson, W., & Kim, H. L. (2018). An introduction to immunology and immunopathology. Allergy, Asthma & Clinical Immunology, 14, 1–8.

Mohan, T., Verma, P., & Nageswara Rao, D. (2013). Novel adjuvants & delivery vehicles for vaccines development: A road ahead. Indian Journal of Medical Research, 138, 779–795.

Morales, J. S., Valenzuela, P. L., Castillo-García, A., Butragueño, J., Jiménez-Pavón, D., Carrera-Bastos, P., & Lucia, A. (2022). The exposome and immune health in times of the COVID-19 pandemic. Nutrients, 14(1), 24.

Mrityunjaya, M., Pavithra, V., Neelam, R., Janhavi, P., Halami, P. M., & Ravindra, P. V. (2020). Immune-boosting, antioxidant and anti-inflammatory food supplements targeting pathogenesis of COVID-19. Frontiers in Immunology, 11, 570122.

Negri, P., Maggi, M., Correa-Aragunde, N., Brasesco, C., Eguaras, M., & Lamattina, L. (2013). Nitric oxide participates at the first steps of Apis mellifera cellular immune activation in response to non-self recognition. Apidologie, 44(5), 575–585.

Oliver, M. A., Bishop, T. F. A., & Marchant, B. P. (2013). Future prospects. In Precision agriculture for sustainability and environmental protection (pp. 265–268). CRC Press.

Pecora, F., Persico, F., Argentiero, A., Neglia, C., & Esposito, S. (2020). The role of micronutrients in support of the immune response against viral infections. Nutrients, 12(10), 3198.

Rahman, M. M., Mosaddik, A., & Alam, A. K. (2021). Traditional foods with their constituent’s antiviral and immune system modulating properties. Heliyon, 7, e05957.

Rasku, T., Kaunonen, M., Thyer, E., Paavilainen, E., & Joronen, K. (2019). The core components of community paramedicine–integrated care in primary care setting: A scoping review. Scandinavian Journal of Caring Sciences, 33(3), 508–521.

Riera Romo, M., Pérez-Martínez, D., & Castillo Ferrer, C. (2016). Innate immunity in vertebrates: An overview. Immunology, 148(2), 125–139.

Robbins, P. D., & Morelli, A. E. (2014). Regulation of immune responses by extracellular vesicles. Nature Reviews Immunology, 14(3), 195–208.

Sanchez-Moreno, C., De Ancos, B., Plaza, L., Elez-Martinez, P., & Cano, M. P. (2009). Nutritional approaches and health-related properties of plant foods processed by high pressure and pulsed electric fields. Critical Reviews in Food Science and Nutrition, 49, 552–576.

Sauer, K., & Cooke, M. P. (2010). Regulation of immune cell development through soluble inositol-1,3,4,5-tetrakisphosphate. Nature Reviews Immunology, 10(3), 257–271.

Schoendorfer, N., & Davies, P. S. W. (2012). Micronutrient interrelationships: Synergism and antagonism. In A. I. Betancourt & H. F. Gaitan (Eds.), Micronutrients (pp. 159–177). Nova Science Publishers.

Stephen, J., Manoharan, D., & Radhakrishnan, M. (2023). Immune boosting functional components of natural foods and its health benefits. Food Production, Processing and Nutrition, 5(1), 61.

Suksmasari, T. B. H. (2015). Multivitamin supplementation supports immune function and ameliorates conditions triggered by reduced air quality. Vitamins and Minerals, 4(1), 1–15.

Thangasamy, T., Subathra, M., Sittadjody, S., Jeyakumar, P., Joyee, A. G., Mendoza, E., & Chinnakkanu, P. (2008). Role of L-carnitine in the modulation of immune response in aged rats. Clinica Chimica Acta, 389(1-2), 19–24.

van Vuuren, J., Thomas, B., Agarwal, G., MacDermott, S., Kinsman, L., O’Meara, P., & Spelten, E. (2021). Reshaping healthcare delivery for elderly patients: The role of community paramedicine; a systematic review. BMC Health Services Research, 21, 1–15.

Widasari, L., Chalid, M. T., Jafar, N., Thaha, A. R., & Dirpan, A. (2020). The role of multimicronutrients on improving better pregnancy outcomes: A literature review. Systematic Reviews in Pharmacy, 11(1), 550–553.

Wiysonge, C., Ndze, V., Kongnyuy, E., & Shey, M. (2017). Vitamin A supplements for reducing mother-to-child HIV transmission. Cochrane Database of Systematic Reviews, 2017, CD003648.

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