References

Abdelsalam, R. M., & Safar, M. M. (2015). Neuroprotective effects of vildagliptin in rat rotenone Parkinson's disease model: role of RAGE-NFκB and Nrf2-antioxidant signaling pathways. Journal of neurochemistry, 133(5), 700-707.
https://doi.org/10.1111/jnc.13087
PMid:25752913

Abu Taher Sagor, M. Angiotensin-II, a potent peptide, participates in the development of hepatic dysfunctions. Immunology, Endocrine & Metabolic Agents in Medicinal Chemistry, 16, 1-17.

Abu Taher Sagor, M., Mahmud Reza, H., Tabassum, N., Sikder, B., Ulla, A., Subhan, N., . . . Ashraful Alam, M. (2016). Supplementation of rosemary leaves (Rosmarinus officinalis) powder attenuates oxidative stress, inflammation and fibrosis in carbon tetrachloride (CCl4) treated rats. Current Nutrition & Food Science, 12(4), 288-295.
https://doi.org/10.2174/1573401312666160816154610

Aktan, F. (2004). iNOS-mediated nitric oxide production and its regulation. Life sciences, 75(6), 639-653.
https://doi.org/10.1016/j.lfs.2003.10.042
PMid:15172174

Alam, M. A., Chowdhury, M. R. H., Jain, P., Sagor, M. A. T., & Reza, H. M. (2015). DPP-4 inhibitor sitagliptin prevents inflammation and oxidative stress of heart and kidney in two kidney and one clip (2K1C) rats. Diabetology & metabolic syndrome, 7(1), 107.
https://doi.org/10.1186/s13098-015-0095-3
PMid:26609328 PMCid:PMC4658771

Alderton, W. K., Cooper, C. E., & Knowles, R. G. (2001). Nitric oxide synthases: structure, function and inhibition. Biochemical Journal, 357(3), 593-615.
https://doi.org/10.1042/0264-6021:3570593
https://doi.org/10.1042/bj3570593
PMid:11463332 PMCid:PMC1221991

Ali, A., Kaur, G., Hamid, H., Abdullah, T., Ali, M., Niwa, M., & Alam, M. (2003). Terminoside A, a new triterpene glycoside from the bark of Terminalia arjuna inhibits nitric oxide production in murine macrophages. Journal of Asian natural products research, 5(2), 137-142.
https://doi.org/10.1080/1028602031000066834
PMid:12765198

Anavi, S., Eisenberg-Bord, M., Hahn-Obercyger, M., Genin, O., Pines, M., & Tirosh, O. (2015). The role of iNOS in cholesterol-induced liver fibrosis. Laboratory investigation, 95(8), 914.
https://doi.org/10.1038/labinvest.2015.67
PMid:26097999

Asano, K., Chee, C., Gaston, B., Lilly, C. M., Gerard, C., Drazen, J. M., & Stamler, J. S. (1994). Constitutive and inducible nitric oxide synthase gene expression, regulation, and activity in human lung epithelial cells. Proceedings of the National Academy of Sciences, 91(21), 10089-10093.
https://doi.org/10.1073/pnas.91.21.10089

AT Sagor, M., M Mohib, M., S Azam, M., Rahman, A., T Tanmoy, F., K Chowdhury, W., . . . A Alam, M. (2016). Angiotensin-II, a Potent Peptide, Participates in the Development of Hepatic Dysfunctions. Immunology, Endocrine & Metabolic Agents in Medicinal Chemistry (Formerly Current Medicinal Chemistry-Immunology, Endocrine and Metabolic Agents), 16(3), 161-177.

Bae, U.-J., Song, M.-Y., Jang, H.-Y., Lim, J. M., Lee, S. Y., Ryu, J.-H., & Park, B.-H. (2015). Emodin isolated from Rheum palmatum prevents cytokine-induced β-cell damage and the development of type 1 diabetes. Journal of Functional Foods, 16, 9-19.
https://doi.org/10.1016/j.jff.2015.04.016

Ballantyne, C. M., & Nambi, V. (2005). Markers of inflammation and their clinical significance. Atherosclerosis Supplements, 6(2), 21-29.
https://doi.org/10.1016/j.atherosclerosissup.2005.02.005
PMid:15823493

Baynosa, R. C., Naig, A. L., Murphy, P. S., Fang, X. H., Stephenson, L. L., Khiabani, K. T., . . . Zamboni, W. A. (2013). The effect of hyperbaric oxygen on nitric oxide synthase activity and expression in ischemia-reperfusion injury. journal of surgical research, 183(1), 355-361.
https://doi.org/10.1016/j.jss.2013.01.004
PMid:23485074

Cabrera-Fuentes, H. A., Ruiz-Meana, M., Simsekyilmaz, S., Kostin, S., Inserte, J., Saffarzadeh, M., . . . Barreto, G. (2014). RNase1 prevents the damaging interplay between extracellular RNA and tumour necrosis factor-α in cardiac ischaemia/reperfusion injury. Thrombosis & Haemostasis, 112(6), 1110-1119.
https://doi.org/10.1160/th14-08-0703
PMid:25354936

Chan, E. D., Chan, J., & Schluger, N. W. (2001). What is the role of nitric oxide in murine and human host defense against tuberculosis? Current knowledge. American journal of respiratory cell and molecular biology, 25(5), 606-612.
https://doi.org/10.1165/ajrcmb.25.5.4487
PMid:11713103

Charles, I. G., Palmer, R., Hickery, M. S., Bayliss, M. T., Chubb, A. P., Hall, V. S., . . . Moncada, S. (1993). Cloning, characterization, and expression of a cDNA encoding an inducible nitric oxide synthase from the human chondrocyte. Proceedings of the National Academy of Sciences, 90(23), 11419-11423.
https://doi.org/10.1073/pnas.90.23.11419

Chen, B.-Y., Lin, D. P.-C., Wu, C.-Y., Teng, M.-C., Sun, C.-Y., Tsai, Y.-T., . . . Chang, H.-H. (2011). Dietary zerumbone prevents mouse cornea from UVB-induced photokeratitis through inhibition of NF-κB, iNOS, and TNF-α expression and reduction of MDA accumulation.

Cho, H. J., Xie, Q., Calaycay, J., Mumford, R. A., Swiderek, K. M., Lee, T. D., & Nathan, C. (1992). Calmodulin is a subunit of nitric oxide synthase from macrophages. Journal of experimental medicine, 176(2), 599-604.
https://doi.org/10.1084/jem.176.2.599
PMid:1380065

Chow, B. S. M., Chew, E. G. Y., Zhao, C., Bathgate, R. A., Hewitson, T. D., & Samuel, C. S. (2012). Relaxin signals through a RXFP1-pERK-nNOS-NO-cGMP-dependent pathway to up-regulate matrix metalloproteinases: the additional involvement of iNOS. PloS one, 7(8), e42714.
https://doi.org/10.1371/journal.pone.0042714
PMid:22936987 PMCid:PMC3425563

Chowdhury, N. U., Farooq, T., Abdullah, S., Mahadi, A. S., Hasan, M. M., Paran, T. Z., . . . Alam, M. A. (2016). Matrix Metalloproteinases (MMP), a Major Responsible Downstream Signaling Molecule for Cellular Damage-A Review. Molecular Enzymology and Drug Targets.
https://doi.org/10.21767/2572-5475.10019

Costa, M. A., Elesgaray, R., Caniffi, C., Fellet, A., Mac Laughlin, M., & Arranz, C. (2010). Role of nitric oxide as a key mediator on cardiovascular actions of atrial natriuretic peptide in spontaneously hypertensive rats. American Journal of Physiology-Heart and Circulatory Physiology, 298(3), H778-H786.
https://doi.org/10.1152/ajpheart.00488.2009
PMid:19783776

Crump, C., Sundquist, J., Winkleby, M. A., & Sundquist, K. (2017). Interactive effects of obesity and physical fitness on risk of ischemic heart disease. International journal of obesity (2005), 41(2), 255.
https://doi.org/10.1038/ijo.2016.209
PMid:27867205 PMCid:PMC5296285

Csont, T., Viappiani, S., Sawicka, J., Slee, S., Altarejos, J. Y., Batinic-Haberle, I., & Schulz, R. (2005). The involvement of superoxide and iNOS-derived NO in cardiac dysfunction induced by pro-inflammatory cytokines. Journal of molecular and cellular cardiology, 39(5), 833-840.
https://doi.org/10.1016/j.yjmcc.2005.07.010
PMid:16171809

Daff, S., Sagami, I., & Shimizu, T. (1999). The 42-amino acid insert in the FMN domain of neuronal nitric-oxide synthase exerts control over Ca2+/calmodulin-dependent electron transfer. Journal of Biological Chemistry, 274(43), 30589-30595.
https://doi.org/10.1074/jbc.274.43.30589
PMid:10521442

Das, A., Xi, L., & Kukreja, R. C. (2005). Phosphodiesterase-5 inhibitor sildenafil preconditions adult cardiac myocytes against necrosis and apoptosis Essential role of nitric oxide signaling. Journal of Biological Chemistry, 280(13), 12944-12955.
https://doi.org/10.1074/jbc.M404706200
PMid:15668244

Das, S., Alagappan, V. K., Bagchi, D., Sharma, H. S., Maulik, N., & Das, D. K. (2005). Coordinated induction of iNOS–VEGF–KDR–eNOS after resveratrol consumption: A potential mechanism for resveratrol preconditioning of the heart. Vascular pharmacology, 42(5), 281-289.
https://doi.org/10.1016/j.vph.2005.02.013
PMid:15905131

Depre, C., Havaux, X., Renkin, J., Vanoverschelde, J. L. J., & Wijns, W. (1999). Expression of inducible nitric oxide synthase in human coronary atherosclerotic plaque. Cardiovascular research, 41(2), 465-472.
https://doi.org/10.1016/S0008-6363(98)00304-6

Depré, C., Wijns, W., Robert, A. M., Renkin, J. P., & Havaux, X. (1997). Pathology of unstable plaque: correlation with the clinical severity of acute coronary syndromes. Journal of the American College of Cardiology, 30(3), 694-702.
https://doi.org/10.1016/S0735-1097(97)00213-1

Dhillon, S. S., Mastropaolo, L. A., Murchie, R., Griffiths, C., Thöni, C., Elkadri, A., . . . Guo, C. (2014). Higher activity of the inducible nitric oxide synthase contributes to very early onset inflammatory bowel disease. Clinical and translational gastroenterology, 5(1), e46.
https://doi.org/10.1038/ctg.2013.17
PMid:24430113 PMCid:PMC3912315

Dias, A. S., Porawski, M., Alonso, M., Marroni, N., Collado, P. S., & González-Gallego, J. (2005). Quercetin decreases oxidative stress, NF-κB activation, and iNOS overexpression in liver of streptozotocin-induced diabetic rats. The Journal of nutrition, 135(10), 2299-2304.
https://doi.org/10.1093/jn/135.10.2299
PMid:16177186

Dwivedi, S. (2007). Terminalia arjuna Wight & Arn.—a useful drug for cardiovascular disorders. Journal of Ethnopharmacology, 114(2), 114-129.
https://doi.org/10.1016/j.jep.2007.08.003
PMid:17875376

Eckel, R. H. (1997). Obesity and heart disease. Circulation, 96(9), 3248-3250.
https://doi.org/10.1161/01.CIR.96.9.3248
PMid:9386201

Eggers, K. M., Oldgren, J., Nordenskjöld, A., & Lindahl, B. (2004). Diagnostic value of serial measurement of cardiac markers in patients with chest pain: limited value of adding myoglobin to troponin I for exclusion of myocardial infarction. American heart journal, 148(4), 574-581.
https://doi.org/10.1016/j.ahj.2004.04.030
PMid:15459585

Escames, G., Khaldy, H., León, J., González, L., & Acu-a-Castroviejo, D. (2004). Changes in iNOS activity, oxidative stress and melatonin levels in hypertensive patients treated with lacidipine. Journal of hypertension, 22(3), 629-635.
https://doi.org/10.1097/00004872-200403000-00027
PMid:15076170

Ferrari, P. F., Palmieri, D., Casazza, A. A., Aliakbarian, B., Perego, P., & Palombo, D. (2015). TNFα-induced endothelial activation is counteracted by polyphenol extract from UV-stressed cyanobacterium Arthrospira platensis. Medicinal Chemistry Research, 24(1), 275-282.
https://doi.org/10.1007/s00044-014-1126-6

Ferreiro, C. R., Chagas, A. C. P., Carvalho, M. H. C., Dantas, A. P., Jatene, M. B., de Souza, L. C. B., & da Luz, P. L. (2001). Influence of hypoxia on nitric oxide synthase activity and gene expression in children with congenital heart disease: a novel pathophysiological adaptive mechanism. Circulation, 103(18), 2272-2276.
https://doi.org/10.1161/01.CIR.103.18.2272
PMid:11342476

Fukumura, D., Gohongi, T., Kadambi, A., Izumi, Y., Ang, J., Yun, C.-O., . . . Jain, R. K. (2001). Predominant role of endothelial nitric oxide synthase in vascular endothelial growth factor-induced angiogenesis and vascular permeability. Proceedings of the National Academy of Sciences, 98(5), 2604-2609.
https://doi.org/10.1073/pnas.041359198
PMid:11226286 PMCid:PMC30185

Funakoshi, H., Kubota, T., Kawamura, N., Machida, Y., Feldman, A. M., Tsutsui, H., . . . Takeshita, A. (2002). Disruption of inducible nitric oxide synthase improves β-adrenergic inotropic responsiveness but not the survival of mice with cytokine-induced cardiomyopathy. Circulation research, 90(9), 959-965.
https://doi.org/10.1161/01.RES.0000017632.83720.68
PMid:12016261

Funakoshi, H., Kubota, T., Machida, Y., Kawamura, N., Feldman, A. M., Tsutsui, H., . . . Takeshita, A. (2002). Involvement of inducible nitric oxide synthase in cardiac dysfunction with tumor necrosis factor-α. American Journal of Physiology-Heart and Circulatory Physiology, 282(6), H2159-H2166.
https://doi.org/10.1152/ajpheart.00872.2001
PMid:12003824

Gupta, A., Rhodes, G. J., Berg, D. T., Gerlitz, B., Molitoris, B. A., & Grinnell, B. W. (2007). Activated protein C ameliorates LPS-induced acute kidney injury and downregulates renal INOS and angiotensin 2. American Journal of Physiology-Renal Physiology, 293(1), F245-F254.
https://doi.org/10.1152/ajprenal.00477.2006
PMid:17409278

Ham, Y.-M., Ko, Y.-J., Song, S.-M., Kim, J., Kim, K.-N., Yun, J.-H., . . . Yoon, W.-J. (2015). Anti-inflammatory effect of litsenolide B2 isolated from Litsea japonica fruit via suppressing NF-κB and MAPK pathways in LPS-induced RAW264. 7 cells. Journal of functional foods, 13, 80-88.
https://doi.org/10.1016/j.jff.2014.12.031

Haywood, G. A., Tsao, P. S., Heiko, E., Mann, M. J., Keeling, P. J., Trindade, P. T., . . . Bishopric, N. H. (1996). Expression of inducible nitric oxide synthase in human heart failure. Circulation, 93(6), 1087-1094.
https://doi.org/10.1161/01.CIR.93.6.1087
PMid:8653828

Heger, J., Gödecke, A., Flögel, U., Merx, M. W., Molojavyi, A., Kühn-Velten, W. N., & Schrader, J. (2002). Cardiac-specific overexpression of inducible nitric oxide synthase does not result in severe cardiac dysfunction. Circulation research, 90(1), 93-99.
https://doi.org/10.1161/hh0102.102757
PMid:11786524

Heron, M., & Anderson, R. N. (2016). Changes in the leading cause of death: recent patterns in heart disease and cancer mortality. Cancer, 400(500,000), 600,000.

Heymes, C., Bendall, J. K., Ratajczak, P., Cave, A. C., Samuel, J.-L., Hasenfuss, G., & Shah, A. M. (2003). Increased myocardial NADPH oxidase activity in human heart failure. Journal of the American College of Cardiology, 41(12), 2164-2171.
https://doi.org/10.1016/S0735-1097(03)00471-6

Ishibashi, M., Hiasa, K.-i., Zhao, Q., Inoue, S., Ohtani, K., Kitamoto, S., . . . Kura, S. (2004). Critical role of monocyte chemoattractant protein-1 receptor CCR2 on monocytes in hypertension-induced vascular inflammation and remodeling. Circulation research, 94(9), 1203-1210.
https://doi.org/10.1161/01.RES.0000126924.23467.A3
PMid:15059935

Islam, M. N., Choi, R. J., Jin, S. E., Kim, Y. S., Ahn, B. R., Zhao, D., . . . Choi, J. S. (2012). Mechanism of anti-inflammatory activity of umbelliferone 6-carboxylic acid isolated from Angelica decursiva. Journal of ethnopharmacology, 144(1), 175-181.
https://doi.org/10.1016/j.jep.2012.08.048
PMid:22981803

Islam, M. N., Ishita, I. J., Jin, S. E., Choi, R. J., Lee, C. M., Kim, Y. S., . . . Choi, J. S. (2013). Anti-inflammatory activity of edible brown alga Saccharina japonica and its constituents pheophorbide a and pheophytin a in LPS-stimulated RAW 264.7 macrophage cells. Food and Chemical Toxicology, 55, 541-548.
https://doi.org/10.1016/j.fct.2013.01.054
PMid:23402855

Janakiram, N. B., & Rao, C. V. (2012). iNOS-selective inhibitors for cancer prevention: promise and progress. Future medicinal chemistry, 4(17), 2193-2204.
https://doi.org/10.4155/fmc.12.168
PMid:23190107 PMCid:PMC3588580

Janssen-Heininger, Y. M., Macara, I., & Mossman, B. T. (1999). Cooperativity between Oxidants and Tumor Necrosis Factor in the Activation of Nuclear Factor (NF)-κ B: Requirement of Ras/Mitogen-Activated Protein Kinases in the Activation of NF-κ B by Oxidants. American journal of respiratory cell and molecular biology, 20(5), 942-952.
https://doi.org/10.1165/ajrcmb.20.5.3452
PMid:10226064

Jiang, Q., Elson-Schwab, I., Courtemanche, C., & Ames, B. N. (2000). γ-Tocopherol and its major metabolite, in contrast to α-tocopherol, inhibit cyclooxygenase activity in macrophages and epithelial cells. Proceedings of the National Academy of Sciences, 97(21), 11494-11499.
https://doi.org/10.1073/pnas.200357097
PMid:11005841 PMCid:PMC17228

Jin, M., Suh, S.-J., Yang, J. H., Lu, Y., Kim, S. J., Kwon, S., . . . Ahn, G. W. (2010). Anti-inflammatory activity of bark of Dioscorea batatas DECNE through the inhibition of iNOS and COX-2 expressions in RAW264. 7 cells via NF-κB and ERK1/2 inactivation. Food and chemical toxicology, 48(11), 3073-3079.
https://doi.org/10.1016/j.fct.2010.07.048
PMid:20691245

Jung, H. A., Jin, S. E., Ahn, B. R., Lee, C. M., & Choi, J. S. (2013). Anti-inflammatory activity of edible brown alga Eisenia bicyclis and its constituents fucosterol and phlorotannins in LPS-stimulated RAW264. 7 macrophages. Food and Chemical Toxicology, 59, 199-206.
https://doi.org/10.1016/j.fct.2013.05.061
PMid:23774261

Kapoor, D., Vijayvergiya, R., & Dhawan, V. (2014). Terminalia arjuna in coronary artery disease: ethnopharmacology, pre-clinical, clinical & safety evaluation. Journal of ethnopharmacology, 155(2), 1029-1045.
https://doi.org/10.1016/j.jep.2014.06.056
PMid:25014508

Kapur, S., Marcotte, B., & Marette, A. (1999). Mechanism of adipose tissue iNOS induction in endotoxemia. American Journal of Physiology-Endocrinology and Metabolism, 276(4), E635-E641.
https://doi.org/10.1152/ajpendo.1999.276.4.E635

Kengatharan, K. M., De Kimpe, S., Robson, C., Foster, S. J., & Thiemermann, C. (1998). Mechanism of gram-positive shock: identification of peptidoglycan and lipoteichoic acid moieties essential in the induction of nitric oxide synthase, shock, and multiple organ failure. Journal of Experimental Medicine, 188(2), 305-315.
https://doi.org/10.1084/jem.188.2.305
PMid:9670043

Keyes, K. T., Ye, Y., Lin, Y., Zhang, C., Perez-Polo, J. R., Gjorstrup, P., & Birnbaum, Y. (2010). Resolvin E1 protects the rat heart against reperfusion injury. American Journal of Physiology-Heart and Circulatory Physiology, 299(1), H153-H164.
https://doi.org/10.1152/ajpheart.01057.2009
PMid:20435846

Khan, M. I., Ostadhadi, S., Mumtaz, F., Momeny, M., Moghaddaskho, F., Hassanipour, M., . . . Dehpour, A. R. (2017). Thalidomide attenuates the development and expression of antinociceptive tolerance to μ-opioid agonist morphine through l-arginine-iNOS and nitric oxide pathway. Biomedicine & Pharmacotherapy, 85, 493-502.
https://doi.org/10.1016/j.biopha.2016.11.056
PMid:27899254

Khan, S., & Jena, G. (2014). Sodium butyrate, a HDAC inhibitor ameliorates eNOS, iNOS and TGF-β1-induced fibrogenesis, apoptosis and DNA damage in the kidney of juvenile diabetic rats. Food and chemical toxicology, 73, 127-139.
https://doi.org/10.1016/j.fct.2014.08.010
PMid:25158305

Khanduja, K. L., Sohi, K. K., Pathak, C. M., & Kaushik, G. (2006). Nimesulide inhibits lipopolysaccharide-induced production of superoxide anions and nitric oxide and iNOS expression in alveolar macrophages. Life sciences, 78(15), 1662-1669.
https://doi.org/10.1016/j.lfs.2005.07.033
PMid:16243362

Kibbe, M. R., Li, J., Nie, S., Watkins, S. C., Lizonova, A., Kovesdi, I., . . . Tzeng, E. (2000). Inducible nitric oxide synthase (iNOS) expression upregulates p21 and inhibits vascular smooth muscle cell proliferation through p42/44 mitogen-activated protein kinase activation and independent of p53 and cyclic guanosine monophosphate. Journal of vascular surgery, 31(6), 1214-1228.
https://doi.org/10.1067/mva.2000.105006
PMid:10842159

Korkmaz, B., Buharalioglu, K., Sahan-Firat, S., Cuez, T., Demiryurek, A. T., & Tunctan, B. (2011). Activation of MEK1/ERK1/2/iNOS/sGC/PKG pathway associated with peroxynitrite formation contributes to hypotension and vascular hyporeactivity in endotoxemic rats. Nitric Oxide, 24(3), 160-172.
https://doi.org/10.1016/j.niox.2011.02.004
PMid:21354320

Lechner, M., Lirk, P., & Rieder, J. (2005). Inducible nitric oxide synthase (iNOS) in tumor biology: the two sides of the same coin. Paper presented at the Seminars in cancer biology.
https://doi.org/10.1016/j.semcancer.2005.04.004
PMid:15914026

Lee, D.-H., Cho, H. J., Kim, J.-T., Choi, J. S., & Joo, C.-K. (2001). Expression of vascular endothelial growth factor and inducible nitric oxide synthase in pterygia. Cornea, 20(7), 738-742.
https://doi.org/10.1097/00003226-200110000-00013
PMid:11588427

Lee, H.-H., Paudel, K. R., & Kim, D.-W. (2015). Terminalia chebula fructus inhibits migration and proliferation of vascular smooth muscle cells and production of inflammatory mediators in RAW 264.7. Evidence-Based Complementary and Alternative Medicine, 2015.

Lee, J. K., Sayers, B. C., Chun, K.-S., Lao, H.-C., Shipley-Phillips, J. K., Bonner, J. C., & Langenbach, R. (2012). Multi-walled carbon nanotubes induce COX-2 and iNOS expression via MAP kinase-dependent and-independent mechanisms in mouse RAW264. 7 macrophages. Particle and fibre toxicology, 9(1), 14.
https://doi.org/10.1186/1743-8977-9-14
PMid:22571318 PMCid:PMC3485091

Li, X., Ye, X., Li, X., Sun, X., Liang, Q., Tao, L., . . . Chen, J. (2011). Salidroside protects against MPP+-induced apoptosis in PC12 cells by inhibiting the NO pathway. Brain research, 1382, 9-18.
https://doi.org/10.1016/j.brainres.2011.01.015
PMid:21241673

Li, Y., Shen, L., & Luo, H. (2016). Luteolin ameliorates dextran sulfate sodium-induced colitis in mice possibly through activation of the Nrf2 signaling pathway. Int Immunopharmacol, 40, 24-31.
https://doi.org/10.1016/j.intimp.2016.08.020
https://doi.org/10.1016/j.intimp.2016.01.027

Lim, H.-W., Kumar, H., Kim, B.-W., More, S. V., Kim, I.-W., Park, J.-I., . . . Choi, D.-K. b-Asarone (cis-2, 4, 5-trimethoxy-1-allyl phenyl), attenuates pro-inflammatory mediators by inhibiting NF-jB signaling and the JNK pathway in LPS activated BV-2 microglia cells.

Liu, F.-q., Zhang, X.-l., Gong, L., Wang, X.-p., Wang, J., Hou, X.-g., . . . Zhang, Y. (2011). Glucagon-like peptide 1 protects microvascular endothelial cells by inactivating the PARP-1/iNOS/NO pathway. Molecular and cellular endocrinology, 339(1-2), 25-33.
https://doi.org/10.1016/j.mce.2011.03.007
PMid:21458523

Liu, X.-m., Peyton, K. J., Wang, X., & Durante, W. (2012). Sildenafil stimulates the expression of gaseous monoxide-generating enzymes in vascular smooth muscle cells via distinct signaling pathways. Biochemical pharmacology, 84(8), 1045-1054.
https://doi.org/10.1016/j.bcp.2012.07.023
PMid:22864061 PMCid:PMC3487387

Loh, S. Y., Giribabu, N., & Salleh, N. (2017). Changes in plasma aldosterone and electrolytes levels, kidney epithelial sodium channel (ENaC) and blood pressure in normotensive WKY and hypertensive SHR rats following gonadectomy and chronic testosterone treatment. Steroids.
https://doi.org/10.1016/j.steroids.2017.09.008
PMid:28954214

Lowenstein, C. J., & Padalko, E. (2004). iNOS (NOS2) at a glance. Journal of cell science, 117(14), 2865-2867.
https://doi.org/10.1242/jcs.01166
PMid:15197240

Luoma, J. S., Strålin, P., Marklund, S. L., Hiltunen, T. P., Särkioja, T., & Ylä-Herttuala, S. (1998). Expression of extracellular SOD and iNOS in macrophages and smooth muscle cells in human and rabbit atherosclerotic lesions: colocalization with epitopes characteristic of oxidized LDL and peroxynitrite-modified proteins. Arteriosclerosis, thrombosis, and vascular biology, 18(2), 157-167.
https://doi.org/10.1161/01.ATV.18.2.157

MacMicking, J., Xie, Q.-w., & Nathan, C. (1997). Nitric oxide and macrophage function. Annual review of immunology, 15(1), 323-350.
https://doi.org/10.1146/annurev.immunol.15.1.323
PMid:9143691

MacMicking, J. D., North, R. J., LaCourse, R., Mudgett, J. S., Shah, S. K., & Nathan, C. F. (1997). Identification of nitric oxide synthase as a protective locus against tuberculosis. Proceedings of the National Academy of Sciences, 94(10), 5243-5248.
https://doi.org/10.1073/pnas.94.10.5243

Marumo, T., Nakaki, T., Hishikawa, K., Hirahashi, J., Suzuki, H., Kato, R., & Saruta, T. (1995). Natriuretic peptide-augmented induction of nitric oxide synthase through cyclic guanosine 3', 5'-monophosphate elevation in vascular smooth muscle cells. Endocrinology, 136(5), 2135-2142.
https://doi.org/10.1210/endo.136.5.7536663
PMid:7536663

Mayer, B., & Hemmens, B. (1997). Biosynthesis and action of nitric oxide in mammalian cells. Trends in biochemical sciences, 22(12), 477-481.
https://doi.org/10.1016/S0968-0004(97)01147-X

Metwaly, H., Ebrahem, M. A.-M., & Saku, T. (2014). Vascular endothelial growth factor (VEGF) and inducible nitric oxide synthase (iNOS) in oral lichen planus: An immunohistochemical study for the correlation between vascular and inflammatory reactions. Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology, 26(3), 390-396.
https://doi.org/10.1016/j.ajoms.2013.09.009

Mogensen, J., Murphy, R. T., Shaw, T., Bahl, A., Redwood, C., Watkins, H., . . . McKenna, W. J. (2004). Severe disease expression of cardiac troponin C and T mutations in patients with idiopathic dilated cardiomyopathy. Journal of the American College of Cardiology, 44(10), 2033-2040.
https://doi.org/10.1016/j.jacc.2004.08.027
PMid:15542288

Mohib, M. M., Afnan, K., Paran, T. Z., Khan, S., Sarker, J., Hasan, N., . . . Sagor, M. A. T. (2017). Beneficial Role of Citrus Fruit Polyphenols Against Hepatic Dysfunctions: A Review. Journal of dietary supplements, 1-29.

Mohib, M. M., Hasan, I., Chowdhury, W. K., Chowdhury, N. U., Mohiuddin, S., Sagor, M. A. T., . . . Alam, M. A. (2016). Role of angiotensin ii in hepatic inflammation through MAPK pathway: A review. Hepatitis.

Mohib, M. M., Rabby, S. F., Paran, T. Z., Hasan, M. M., Ahmed, I., Hasan, N., . . . Mohiuddin, S. (2016). Protective role of green tea on diabetic nephropathy—A review. Cogent Biology, 2(1), 1248166.

Mohib, M. M., Rabby, S. M. F., Paran, T. Z., Hasan, M. M., Ahmed, I., Hasan, N., . . . Hsu, T.-C. (2016). Protective role of green tea on diabetic nephropathy -A review. Cogent Biology, 1248166. doi:10.1080/23312025.2016.1248166
https://doi.org/10.1080/23312025.2016.1248166

Müller-Werdan, U., Schumann, H., Fuchs, R., Reithmann, C., Loppnow, H., Koch, S., . . . Jungblut, P. (1997). Tumor Necrosis Factorα (TNFα) is Cardiodepressant in Pathophysiologically Relevant Concentrations Without Inducing Inducible Nitric Oxide-(NO)-Synthase (iNOS) or Triggering Serious Cytotoxicity. Journal of molecular and cellular cardiology, 29(11), 2915-2923.
https://doi.org/10.1006/jmcc.1997.0526
PMid:9405166

Mungrue, I. N., Gros, R., You, X., Pirani, A., Azad, A., Csont, T., . . . Husain, M. (2002a). Cardiomyocyte overexpression of iNOS in mice results in peroxynitrite generation, heart block, and sudden death. The Journal of clinical investigation, 109(6), 735-743.
https://doi.org/10.1172/JCI0213265
PMid:11901182 PMCid:PMC150906

Mungrue, I. N., Gros, R., You, X., Pirani, A., Azad, A., Csont, T., . . . Husain, M. (2002b). Cardiomyocyte overexpression of iNOS in mice results in peroxynitrite generation, heart block, and sudden death. The Journal of clinical investigation, 109(6), 735.
https://doi.org/10.1172/JCI0213265
PMid:11901182 PMCid:PMC150906

Nathan, C. (1992). Nitric oxide as a secretory product of mammalian cells. The FASEB journal, 6(12), 3051-3064.
https://doi.org/10.1096/fasebj.6.12.1381691
PMid:1381691

Padureanu, V., Enescu, A. S., Silosi, I., Fortofoiu, M., Enescu, A., Bogdan, M., . . . Mita, A. (2017). The association between chronic pancreatitis and the iNOS-2087A> G polymorphism. Romanian Journal of Internal Medicine, 55(2), 89-95.
https://doi.org/10.1515/rjim-2017-0009
PMid:28125406

Palmer, J., Guillard, F., Laurijssens, B., Wentz, A., Dixon, R., & Williams, P. (2009). A randomised, single-blind, placebo-controlled, adaptive clinical trial of GW274150, a selective iNOS inhibitor, in the treatment of acute migraine. Cephalalgia, 29(1), 124.

Papapetropoulos, A., García-Carde-a, G., Madri, J. A., & Sessa, W. C. (1997). Nitric oxide production contributes to the angiogenic properties of vascular endothelial growth factor in human endothelial cells. The Journal of clinical investigation, 100(12), 3131-3139.
https://doi.org/10.1172/JCI119868
PMid:9399960 PMCid:PMC508526

Piplani, H., Vaish, V., & Sanyal, S. N. (2012). Dolastatin 15, a mollusk linear peptide, and Celecoxib, a selective cyclooxygenase-2 inhibitor, prevent preneoplastic colonic lesions and induce apoptosis through inhibition of the regulatory transcription factor NF-κB and an inflammatory protein, iNOS. European Journal of Cancer Prevention, 21(6), 511-522.
https://doi.org/10.1097/CEJ.0b013e328351c69d
PMid:22441428

Ramlagan, P., Rondeau, P., Planesse, C., Neergheen-Bhujun, V. S., Fawdar, S., Bourdon, E., & Bahorun, T. (2017). Punica granatum L. mesocarp suppresses advanced glycation end products (AGEs)-and H 2 O 2-induced oxidative stress and pro-inflammatory biomarkers. Journal of Functional Foods, 29, 115-126.
https://doi.org/10.1016/j.jff.2016.12.007

Rasoanaivo, P., Wright, C. W., Willcox, M. L., & Gilbert, B. (2011). Whole plant extracts versus single compounds for the treatment of malaria: synergy and positive interactions. Malaria Journal, 10(1), S4.
https://doi.org/10.1186/1475-2875-10-S1-S4
PMid:21411015 PMCid:PMC3059462

Rodrigues, J. P. F., Caldas, I. S., Gonçalves, R. V., Almeida, L. A., Souza, R. L. M., & Novaes, R. D. (2017). S. mansoni-T. cruzi co-infection modulates arginase-1/iNOS expression, liver and heart disease in mice. Nitric Oxide, 66, 43-52.
https://doi.org/10.1016/j.niox.2017.02.013
PMid:28268114

Romano, B., Pagano, E., Orlando, P., Capasso, R., Cascio, M. G., Pertwee, R., . . . Borrelli, F. (2016). Pure Δ 9-tetrahydrocannabivarin and a Cannabis sativa extract with high content in Δ 9-tetrahydrocannabivarin inhibit nitrite production in murine peritoneal macrophages. Pharmacological Research, 113, 199-208.
https://doi.org/10.1016/j.phrs.2016.07.045
PMid:27498155

Ryu, S., Shin, J.-S., Cho, Y.-W., Kim, H. K., Paik, S. H., Lee, J. H., . . . Lee, K.-T. (2013). Fimasartan, anti-hypertension drug, suppressed inducible nitric oxide synthase expressions via nuclear factor-kappa B and activator protein-1 inactivation. Biological and Pharmaceutical Bulletin, 36(3), 467-474.
https://doi.org/10.1248/bpb.b12-00859
PMid:23449332

Sagor, M. A. T., Mohib, M., Tabassum, N., Ahmed, I., & Reza, H. (2016). Fresh seed supplementation of Syzygium cumini attenuated oxidative stress, inflammation, fibrosis, iron overload, hepatic dysfunction and renal injury in acetaminophen induced rats. Journal of Drug Metabolism & Toxicology, 7(2).

Sagor, M. A. T., Tabassum, N., Potol, M. A., & Alam, M. A. (2015). Xanthine oxidase inhibitor, allopurinol, prevented oxidative stress, fibrosis, and myocardial damage in isoproterenol induced aged rats. Oxidative medicine and cellular longevity, 2015.
https://doi.org/10.1155/2015/478039
PMid:26137187 PMCid:PMC4475550

Sagor, M. A. T., Tabassum, N., Potol, M. A., & Alam, M. A. (2015). Xanthine Oxidase Inhibitor, Allopurinol, Prevented Oxidative Stress, Fibrosis, and Myocardial Damage in Isoproterenol Induced Aged Rats. Oxidative Medicine and Cellular Longevity, 2015, 9. doi:10.1155/2015/478039
https://doi.org/10.1155/2015/478039

Salerno, J. C., Harris, D. E., Irizarry, K., Patel, B., Morales, A. J., Smith, S. M., . . . Jones, C. L. (1997). An autoinhibitory control element defines calcium-regulated isoforms of nitric oxide synthase. Journal of Biological Chemistry, 272(47), 29769-29777.
https://doi.org/10.1074/jbc.272.47.29769
PMid:9368047

Salvemini, D., Nucci, G., Sneddon, J. M., & Vane, J. R. (1989). Superoxide anions enhance platelet adhesion and aggregation. British journal of pharmacology, 97(4), 1145-1150.
https://doi.org/10.1111/j.1476-5381.1989.tb12572.x
PMid:2551440 PMCid:PMC1854596

Sangartit, W., Pakdeechote, P., Kukongviriyapan, V., Donpunha, W., Shibahara, S., & Kukongviriyapan, U. (2016). Tetrahydrocurcumin in combination with deferiprone attenuates hypertension, vascular dysfunction, baroreflex dysfunction, and oxidative stress in iron-overloaded mice. Vascular Pharmacology, 87, 199-208.
https://doi.org/10.1016/j.vph.2016.10.001
PMid:27713040

Sarady, J. K., Zuckerbraun, B. S., Bilban, M., Wagner, O., Usheva, A., Liu, F., . . . Otterbein, L. E. (2004). Carbon monoxide protection against endotoxic shock involves reciprocal effects on iNOS in the lung and liver. The FASEB journal, 18(7), 854-856.
https://doi.org/10.1096/fj.03-0643fje
PMid:15001560

Satoh, M., Nakamura, M., Tamura, G., Makita, S., Segawa, I., Tashiro, A., . . . Hiramori, K. (1997). Inducible nitric oxide synthase and tumor necrosis factor-alpha in myocardium in human dilated cardiomyopathy. Journal of the American College of Cardiology, 29(4), 716-724.
https://doi.org/10.1016/S0735-1097(96)00567-0

Seccombe, J. F., Pearson, P. J., & Schaff, H. V. (1994). Oxygen radical—mediated vascular injury selectively inhibits receptor-dependent release of nitric oxide from canine coronary arteries. The Journal of thoracic and cardiovascular surgery, 107(2), 505-509.
PMid:8302070

Seo, S., Shin, J.-S., Lee, W.-S., Rhee, Y. K., Cho, C.-W., Hong, H.-D., & Lee, K.-T. (2017). Anti-colitis effect of Lactobacillus sakei K040706 via suppression of inflammatory responses in the dextran sulfate sodium-induced colitis mice model. Journal of Functional Foods, 29, 256-268.
https://doi.org/10.1016/j.jff.2016.12.045

Shabeeh, H., Khan, S., Jiang, B., Brett, S., Melikian, N., Casadei, B., . . . Shah, A. M. (2017). Blood Pressure in Healthy Humans Is Regulated by Neuronal NO SynthaseNovelty and Significance. Hypertension, 69(5), 970-976.
https://doi.org/10.1161/HYPERTENSIONAHA.116.08792
PMid:28264923 PMCid:PMC5389591

Shimabukuro, M., Ohneda, M., Lee, Y., & Unger, R. H. (1997). Role of nitric oxide in obesity-induced beta cell disease. Journal of Clinical Investigation, 100(2), 290.
https://doi.org/10.1172/JCI119534
PMid:9218505 PMCid:PMC508191

Simsekyilmaz, S., Cabrera-Fuentes, H. A., Meiler, S., Kostin, S., Baumer, Y., Liehn, E. A., . . . Zernecke, A. (2013). The role of extracellular RNA in atherosclerotic plaque formation in mice. Circulation, CIRCULATIONAHA. 113.002562.

Sun, Y., Carretero, O. A., Xu, J., Rhaleb, N.-E., Wang, F., Lin, C., . . . Yang, X.-P. (2005). Lack of inducible NO synthase reduces oxidative stress and enhances cardiac response to isoproterenol in mice with deoxycorticosterone acetate–salt hypertension. Hypertension, 46(6), 1355-1361.
https://doi.org/10.1161/01.HYP.0000192651.06674.3f
PMid:16286571 PMCid:PMC4601605

Taylor, B. S., & Geller, D. A. (2000). Molecular regulation of the human inducible nitric oxide synthase (iNOS) gene. Shock (Augusta, Ga.), 13(6), 413-424.
https://doi.org/10.1097/00024382-200006000-00001

Tikellis, C., Thomas, M. C., Harcourt, B. E., Coughlan, M. T., Pete, J., Bialkowski, K., . . . Forbes, J. M. (2008). Cardiac inflammation associated with a Western diet is mediated via activation of RAGE by AGEs. American Journal of Physiology-Endocrinology and Metabolism, 295(2), E323-E330.
https://doi.org/10.1152/ajpendo.00024.2008
PMid:18477705 PMCid:PMC2652498

Vannini, F., Kashfi, K., & Nath, N. (2015). The dual role of iNOS in cancer. Redox biology, 6, 334-343.
https://doi.org/10.1016/j.redox.2015.08.009
PMid:26335399 PMCid:PMC4565017

Vejlstrup, N. G., Bouloumie, A., Boesgaard, S., Andersen, C. B., Nielsen-Kudsk, J. E., Mortensen, S. A., . . . Aldershvile, J. (1998). Inducible nitric oxide synthase (iNOS) in the human heart: expression and localization in congestive heart failure. Journal of molecular and cellular cardiology, 30(6), 1215-1223.
https://doi.org/10.1006/jmcc.1998.0686
PMid:9689595

Wang, W. Z., Fang, X. H., Stepheson, L. L., Khiabani, K. T., & Zamboni, W. A. (2004). NOS upregulation attenuates vascular endothelial dysfunction in the late phase of ischemic preconditioning in skeletal muscle. Journal of orthopaedic research, 22(3), 578-585.
https://doi.org/10.1016/j.orthres.2003.10.004
PMid:15099638

Westermann, D., Lindner, D., Kasner, M., Zietsch, C., Savvatis, K., Escher, F., . . . Riad, A. (2010). Cardiac inflammation contributes to changes in the extracellular matrix in patients with heart failure and normal ejection fraction. Circulation: Heart Failure, CIRCHEARTFAILURE. 109.931451.

Wever, R. M., Lüscher, T. F., Cosentino, F., & Rabelink, T. J. (1998). Atherosclerosis and the two faces of endothelial nitric oxide synthase. Circulation, 97(1), 108-112.
https://doi.org/10.1161/01.CIR.97.1.108
PMid:9443438

Wong, M.-L., Rettori, V., Amer, A.-S., Bongiorno, P. B., Canteros, G., McCann, S. M., . . . Licinio, J. (1996). Inducible nitric oxide synthase gene expression in the brain during systemic inflammation. Nature medicine, 2(5), 581-584.
https://doi.org/10.1038/nm0596-581
PMid:8616720

Xia, M., Ling, W. H., Ma, J., Kitts, D. D., & Zawistowski, J. (2003). Supplementation of diets with the black rice pigment fraction attenuates atherosclerotic plaque formation in apolipoprotein e deficient mice. The Journal of nutrition, 133(3), 744-751.
https://doi.org/10.1093/jn/133.3.744
PMid:12612147

Xia, X., Ling, W., Ma, J., Xia, M., Hou, M., Wang, Q., . . . Tang, Z. (2006). An anthocyanin-rich extract from black rice enhances atherosclerotic plaque stabilization in apolipoprotein E–deficient mice. The Journal of nutrition, 136(8), 2220-2225.
https://doi.org/10.1093/jn/136.8.2220
PMid:16857844

Xu, W., Charles, I. G., Moncada, S., Gorman, P., Sheer, D., Liu, L., & Emson, P. (1994). Mapping of the genes encoding human inducible and endothelial nitric oxide synthase (NOS2 and NOS3) to the pericentric region of chromosome 17 and to chromosome 7, respectively. Genomics, 21(2), 419-422.
https://doi.org/10.1006/geno.1994.1286
PMid:7522210

Xuan, Y.-T., Guo, Y., Han, H., Zhu, Y., & Bolli, R. (2001). An essential role of the JAK-STAT pathway in ischemic preconditioning. Proceedings of the National Academy of Sciences, 98(16), 9050-9055.
https://doi.org/10.1073/pnas.161283798
PMid:11481471 PMCid:PMC55371

Yang, B., Larson, D. F., & Watson, R. R. (2004). Modulation of iNOS activity in age-related cardiac dysfunction. Life sciences, 75(6), 655-667.
https://doi.org/10.1016/j.lfs.2003.09.076
PMid:15172175

Ying, L., & Hofseth, L. J. (2007). An emerging role for endothelial nitric oxide synthase in chronic inflammation and cancer. Cancer Research, 67(4), 1407-1410.
https://doi.org/10.1158/0008-5472.CAN-06-2149
PMid:17308075

Yoda, Y., Amagase, K., Kato, S., Tokioka, S., Murano, M., Kakimoto, K., . . . Higuchi, K. (2010). Prevention by lansoprazole, a proton pump inhibitor, of indomethacin-induced small intestinal ulceration in rats through induction of heme oxygenase-1. Journal of Physiology and Pharmacology, 61(3), 287.
PMid:20610858

Yu, G., Cheng, M., Wang, W., Zhao, R., & Liu, Z. (2017). Involvement of WNK1-mediated potassium channels in the sexual dimorphism of blood pressure. Biochemical and Biophysical Research Communications, 485(2), 255-260.
https://doi.org/10.1016/j.bbrc.2017.02.098
PMid:28237360

Yu, X. W., Chen, Q., Kennedy, R. H., & Liu, S. J. (2005). Inhibition of sarcoplasmic reticular function by chronic interleukin-6 exposure via iNOS in adult ventricular myocytes. The Journal of physiology, 566(2), 327-340.
https://doi.org/10.1113/jphysiol.2005.086686
https://doi.org/10.1113/jphysiol.2002.034223
PMid:15845578

Zhang, J., Peng, B., & Chen, X. (2005). Expressions of nuclear factor κB, inducible nitric oxide synthase, and vascular endothelial growth factor in adenoid cystic carcinoma of salivary glands: correlations with the angiogenesis and clinical outcome. Clinical Cancer Research, 11(20), 7334-
https://doi.org/10.1158/1078-0432.CCR-05-0241
PMid:16243805