Influence of Ecological Zones on Immune Function and Viability in Sur Karakol Lambs: A Comparative Study of Mountainous and Desert-Steppe Regions
Mukhitdinov Shavkat Mukhammedzhanovich 1*, Dilmurod Davronovich Aliyev 2, Ismailov Kamil Tuygunovich 3, Ochilov Behzod Salimovich 4, Avazov Otabek Safarali Ugli 5
Journal of Angiotherapy 8(7) 1-7 https://doi.org/10.25163/angiotherapy.879813
Submitted: 16 May 2024 Revised: 18 July 2024 Published: 23 July 2024
Abstract
Background: The adaptation of Sur Karakol lambs to different ecological zones is crucial for their survival and productivity. This study explores the biochemical and immunological responses of lambs raised in the mountainous region of Samarkand and the desert-steppe region of Kashkadarya. The study aimed to evaluate the phagocytic, bactericidal, and lysozyme activities in the blood, along with immunoglobulin levels, to assess the immune status of lambs in these contrasting environments. Methods: Blood samples were collected from lambs aged 120-135 days to measure phagocytic activity, bactericidal activity, lysozyme activity, and immunoglobulin levels (IgA, IgM, IgG). Phagocytic activity was determined by the percentage of neutrophils engulfing bacteria, bactericidal activity by the ability of blood to kill bacteria, and lysozyme activity by the degradation of bacterial cell walls. Results: The study found that lambs in the desert-steppe region exhibited slightly higher phagocytic activity (46.5%-47.4%), bactericidal activity (50.9%-52.0%), and lysozyme activity (46.7%-49.6%) compared to those in the mountainous region. Immunoglobulin levels showed a typical pattern of increasing IgA and IgM with age, while IgG decreased, indicating a normal transition from maternal to self-generated immunity. Conclusion: The harsher conditions of the desert-steppe region appear to stimulate a stronger innate immune response in Sur Karakol lambs, enhancing their resilience and survival rates compared to lambs in the mountainous region. These findings suggest that environmental factors significantly influence the immune competence and overall vitality of lambs.
Keywords: Sur Karakol lambs, Immune function, Ecological adaptation, Lysozyme activity, Desert-steppe region
References
Aliev, D. D. (2021). Productivity of Surkhandarya Sur Karakol sheep physiological aspects of growth. Disser... Biol.Fan Doc; 03.00.08. Aliev Dilmurod Davronovich. Tashkent.
Bate, L. A., & Hacher, R. (1982). Estrogens and piglet viability. Journal of Animal Science, 54(5), 1012-1016.
Efimova, L. I., & Saiduldin, E. T. (2004). Protective mechanisms of the organism: Immunodiagnostics and immunoprophylaxis of infectious diseases of animals. Voronezh: VSAU.
Ismailov, K. T., & Aliyev, D. D. (2022). Relationship of potassium content in the blood with reproductive physiology of Sur Karakol sheep. Scientific Journal of Agrobiotechnology and Veterinary Medicine, 642-645.
Ismoilov, K. T., Aliyev, D. D., & Okhunova, S. (2023). Dependence of microelements on viability and hematological indicators of Sur Karakol lambs. Food Insecurity: National and Global Problems, (3), 87-91.
Leshnina, M. N., Maksimov, V. I., Shukanov, R. A., Yeremeyev, V. N., Sofronov, V. G., & Mullakaev, A. O. (2019). Formation and development of the immunophysiological status of pigs in postnatal ontogenesis when prescribing biogenic compounds, taking into account regional climatic and geographical features: Monograph. Kazan: Otchestvo Publishing House.
Loke, Y. W., & King, A. (1995). Human implantation: Cell biology and immunology. Cambridge.
Mukhitdinov, Sh., Aliyev, D., Ismoilov, K., & Mamurova, G. (2020). The role of biologically active substances in the blood in increasing the productivity of sheep. European Journal of Molecular & Clinical Medicine, 7(03).
Obukhov, M. N. (2003). Productivity and natural resistance of pigs of new meat types in connection with technological and preventive measures: Abstract of the dissertation... Candidate of Agricultural Sciences: 06.02.04. Peresianovsky.
Pirogov, R. V. (1978). Conversations about new immunology. Moscow: Molodaya Gvardiya.
Pirogov, R. V. (1982). Immunology. Moscow: Meditsina.
Sazonova, I. A. (2013). Morphological composition of blood and immunity indicators of Volgograd breed lambs depending on environmental factors. Sheep, Goats, Wool Business, (4), 15-16.
Sazonova, I. A. (2016). Biological value of meat of Tsigai breed lambs depending on the natural-climatic zone of the Volga region. Sheep, Goats, Wool Business, (4), 24-27.
Timashev, I. Z., & Selkin, I. I. (1975). Fertility and quality of offspring of ewes inseminated by rams of different breeds. Stavropol, 37(1), 43-54.
View Dimensions
View Altmetric
Save
Citation
View
Share