EMAN RESEARCH PUBLISHING | Journal | <p>Antimicrobial efficacy of commercially available dentifrices against newly isolated <em>Streptococcus mutans</em></p>
Microbial and anti-microbial compound biology
RESEARCH ARTICLE   (Open Access)

Antimicrobial efficacy of commercially available dentifrices against newly isolated Streptococcus mutans

Md. Shahadat Hossaina, Nusrat Jahan Antoraa and Mohammad Shahnoor Hossaina*

+ Author Affiliations

Microbial Bioactives 1(1) 029-032 https://doi.org/10.25163/microbbioacts.11011A0405090818

Submitted: 04 July 2018  Revised: 05 August 2018  Published: 08 August 2018 

Significance: Fluoride and triclosan containing dentifrices can be used to prevent oral infections.

Abstract


Background: The aim of the present study was to evaluate the anticariogenic activities of commercially available dentifrices such as, toothpastes and mouthwashes against the most prominent cariogenic bacteria S. mutansMethods: Agar well diffusion method was employed to investigate the antibacterial activity against newly isolated clinical strains. Statistical analysis was performed using SPSS version 20 and one-way ANOVA and student t-test were used to compare the zone of inhibition. Results: We found that most of the commercially available dentifrices have antibacterial activity against S. mutans clinical isolates. We also found that fluoride and triclosan containing toothpaste has comparatively higher antibacterial effect than others. In addition, we observed that mouthwashes have relatively lower antibacterial activity than the toothpastes. Conclusions: In sum, our study indicated that sodium fluoride and triclosan containing toothpastes can be effectively used to maintain a good oral hygiene to prevent dental caries and other related diseases.

Keywords: Dentifrices, toothpaste, mouthwash, dental caries, antimicrobial activity, S. mutans

Significance: Fluoride and triclosan containing dentifrices can be used to prevent oral infections.

Abbreviations: CFU, Colony forming unit; PCR, Polymerase Chain Reaction; ANOVA, Analysis of Variance; SPSS, Statistical Package for the Social Sciences.

References


Barnett, M. L. (2006). The oral-systemic disease connection. An update for the practicing dentist. J Am Dent Assoc, 137 Suppl, 5S-6S.

Buzalaf, M. A., Pessan, J. P., Honorio, H. M., & ten Cate, J. M. (2011). Mechanisms of action of fluoride for caries control. Monogr Oral Sci, 22, 97-114. doi:10.1159/000325151

Caufield, P. W., Li, Y., & Dasanayake, A. (2005). Dental caries: an infectious and transmissible disease. Compend Contin Educ Dent, 26(5 Suppl 1), 10-16.

Davies, R., Scully, C., & Preston, A. J. (2010). Dentifrices--an update. Med Oral Patol Oral Cir Bucal, 15(6), e976-982.

Davies, R. M., Ellwood, R. P., & Davies, G. M. (2004). The effectiveness of a toothpaste containing triclosan and polyvinyl-methyl ether maleic acid copolymer in improving plaque control and gingival health: a systematic review. J Clin Periodontol, 31(12), 1029-1033. doi:10.1111/j.1600-051X.2004.00614.x

Dye, B. A., Li, X., & Thorton-Evans, G. (2012). Oral health disparities as determined by selected healthy people 2020 oral health objectives for the United States, 2009-2010. NCHS Data Brief(104), 1-8.

Fine, D. H., Furgang, D., Markowitz, K., Sreenivasan, P. K., Klimpel, K., & De Vizio, W. (2006). The antimicrobial effect of a triclosan/copolymer dentifrice on oral microorganisms in vivo. J Am Dent Assoc, 137(10), 1406-1413.

Herlofson, B. B., & Barkvoll, P. (1996). Oral mucosal desquamation caused by two toothpaste detergents in an experimental model. Eur J Oral Sci, 104(1), 21-26.

Hossain, M. S., & Biswas, I. (2011). Mutacins from Streptococcus mutans UA159 are active against multiple streptococcal species. Appl Environ Microbiol, 77(7), 2428-2434. doi:10.1128/AEM.02320-10

Inetianbor JE., E. G., Yakubu JM. and Ogodo AC. (2014). In-vitro antibacterial activity of commonly used toothpastes in nigeria against dental pathogens. J Adv Sci Res., 5(2)(40-45).

J Okpalugo J., I. K., Inyang US. . (2009.). Toothpaste formulation efficacy in reducing oral flora. Tropical Journal of Pharmaceutical Research, 8 (1), 71-77.

Kampoo, K., Teanpaisan, R., Ledder, R. G., & McBain, A. J. (2014). Oral bacterial communities in individuals with type 2 diabetes who live in southern Thailand. Appl Environ Microbiol, 80(2), 662-671. doi:10.1128/AEM.02821-13

Khan, A. A., Jain, S. K., & Shrivastav, A. (2008). Prevalence of Dental Caries among the Population of Gwalior (India) in Relation of Different Associated Factors. Eur J Dent, 2(2), 81-85.

Kilian, M., Chapple, I. L., Hannig, M., Marsh, P. D., Meuric, V., Pedersen, A. M., . . . Zaura, E. (2016). The oral microbiome - an update for oral healthcare professionals. Br Dent J, 221(10), 657-666. doi:10.1038/sj.bdj.2016.865

Lim, Y., Totsika, M., Morrison, M., & Punyadeera, C. (2017). Oral Microbiome: A New Biomarker Reservoir for Oral and Oropharyngeal Cancers. Theranostics, 7(17), 4313-4321. doi:10.7150/thno.21804

Loyola-Rodriguez, J. P., Martinez-Martinez, R. E., Abud-Mendoza, C., Patino-Marin, N., & Seymour, G. J. (2010). Rheumatoid arthritis and the role of oral bacteria. J Oral Microbiol, 2. doi:10.3402/jom.v2i0.5784

Marinho, V. C., Higgins, J. P., Sheiham, A., & Logan, S. (2003). Fluoride toothpastes for preventing dental caries in children and adolescents. Cochrane Database Syst Rev(1), CD002278. doi:10.1002/14651858.CD002278

Marquis, R. E. (1995). Antimicrobial actions of fluoride for oral bacteria. Can J Microbiol, 41(11), 955-964.

Petersen, R. C. (2016). Triclosan antimicrobial polymers. AIMS Mol Sci, 3(1), 88-103. doi:10.3934/molsci.2016.1.88

Prasanth, M. (2011). Antimicrobial efficacy of different toothpastes and mouthrinses: an in vitro study. Dent Res J (Isfahan), 8(2), 85-94.

Rahman M., I. M., Islam MN., Hossain MS. (2015.). Isolation and Identification of Oral Bacteria and Characterization for Bacteriocin Production and Antimicrobial Sensitivity. Dhaka Univ. J. Pharm. Sci., 14((1)), 103-109.

Robertson, D., & Smith, A. J. (2009). The microbiology of the acute dental abscess. J Med Microbiol, 58(Pt 2), 155-162. doi:10.1099/jmm.0.003517-0

Ruff, R. R., & Niederman, R. (2018). Comparative effectiveness of treatments to prevent dental caries given to rural children in school-based settings: protocol for a cluster randomised controlled trial. BMJ Open, 8(4), e022646. doi:10.1136/bmjopen-2018-022646

Struzycka, I. (2014). The oral microbiome in dental caries. Pol J Microbiol, 63(2), 127-135.

Walker, C. (1990). Effects of sanguinarine and Sanguinaria extract on the microbiota associated with the oral cavity. J Can Dent Assoc, 56(7 Suppl), 13-30.

Committee on Publication Ethics

Buy PDF
Full Text
Export Citation

View Dimensions


View Plumx



View Altmetric



0
Save
0
Citation
373
View
0
Share