The Interplay Between Oral Health and Systemic Diseases: Review of the Implications for General Medicine&nbsp;

Ali Jamal Alanazi; &rlm;Ahmed Saleh Alghamdi; &rlm;Abdulrahman Munawir Alanazi; &rlm;Rayid Mohammed Alanazi; &rlm;Yousef Mansour Aloudah; &rlm;Ali Eid Atallah Albalawi; Yousef Sulaiman Yahya Alharbi; Talal Fares Awadh Almutairi

doi:10.25163/angiotherapy.6210156

Integrative Biomedical Research | Online ISSN 2207-872X

REVIEWS (Open Access)

The Interplay Between Oral Health and Systemic Diseases: Review of the Implications for General Medicine

Ali Jamal Alanazi ^1*, ‏Ahmed Saleh Alghamdi ¹, ‏Abdulrahman Munawir Alanazi ¹, ‏Rayid Mohammed Alanazi ¹, ‏Yousef Mansour Aloudah ¹, ‏Ali Eid Atallah Albalawi ¹, Yousef Sulaiman Yahya Alharbi ¹, Talal Fares Awadh Almutairi ¹

+ Author Affiliations

Journal of Angiotherapy 6 (2) 1-7 https://doi.org/10.25163/angiotherapy.6210156

Submitted: 02 October 2022 Revised: 05 December 2022 Published: 06 December 2022

Abstract

The correlation between oral health and systemic disorders has garnered considerable interest in recent years, as research increasingly emphasizes the complex relationships among the oral microbiota, periodontal diseases, and other systemic ailments. Substandard oral health has been associated with chronic conditions like diabetes, cardiovascular disease, respiratory infections, and neurological problems, underscoring the need to maintain excellent dental hygiene for overall well-being. The reciprocal association between periodontal disease and ailments such as diabetes indicates that oral inflammation may aggravate systemic problems, while systemic diseases may also lead to the decline of dental health. Moreover, new research has found certain bacterial strains, such as Streptococcus mutans, that may affect illnesses such as atherosclerosis and inflammatory bowel disease. This review discusses the relationship between oral health and systemic disorders by reviewing current data on the molecular processes involved, such as inflammation, immunological responses, and microbial translocation. It also investigates the function of oral biofilms in disease progression and addresses how innovations in oral healthcare and preventative measures might reduce the risk of systemic illnesses. The study emphasizes the need for an interdisciplinary strategy that integrates dentistry and general care to enhance patient outcomes. Comprehending these associations may result in enhanced prevention measures, refined diagnostic instruments, and focused therapy approaches for individuals afflicted with both oral and systemic ailments. Future research should prioritize the development of integrated healthcare models that acknowledge the mouth cavity as an essential element of overall health.

Keywords: Oral health, systemic disorders, periodontitis, microbiota, inflammation, chronic diseases.

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