Journal of Angiotherapy
Angiogenesis, Inflammation & Therapeutics | Online ISSN  2207-872X
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Contents Vol 8 (1)

An In-Depth Analysis of Microorganisms Linked to Various Forms of Hospital-Acquired Infections: A Systematic Review

Nadirah Yusof 1,  Rabiatul Basria S. M. N. Mydin 1,2*, Chandrarohini Saravanan 2,3,4, Nor Hazliana Harun 2,5, Siti Salmah Noordin 5

+ Author Affiliations

Journal of Angiotherapy 8 (1) 1-9 https://doi.org/10.25163/angiotherapy.819381

Submitted: 11 November 2023 Revised: 20 December 2023  Published: 12 January 2024 

Abstract

Nosocomial infections (NIs) represent one of the serious public health concerns worldwide that are linked with healthcare-associated infections. The present study reviewed the microorganisms associated with various types of NIs. The data search strategy was guided by the PRISMA-P protocol with the utilization of various search engine databases (PubMed, Springer Link, Science Direct, and Google Scholar) and pre-determined keywords. The search retrieved 504 articles from 2014 to 2019. Based on the inclusion and exclusion criteria stated, only a total of 63 articles have been discussed further in this study. The signatures of NIs can be described by microorganisms associated with the transmission route groups (Nosocomial bloodstream infections-BSI, Hospital Acquired Pneumonia-HAP, Catheter-Associated Urinary Tract Infection-CAUTI, Surgical Site Infection-SSI). BSI is the major cause of morbidity and mortality in hospitals. HAP is the most frequently reported case including Ventilator-associated Pneumonia-VAP. Microorganisms such as Acinetobacter Baumannii spp., Escherichia spp., Streptococcus spp., Staphylococcus aureus spp., and Pseudomonas spp. pathogens are commonly associated with NIs. Recently, the healthcare challenge is also associated with Multi-Drug Resistant (MDR) related strains that contribute to a significantly high mortality rate, especially in immune-compromised patients. Hence, the emergence of various nosocomial infections marked the relevant steps and measures that need to be taken with effective precautions.    

Keywords: nosocomial infection, communicable disease, hospital-acquired infection,  disease, health, multi-drug resistant

References

Azar, J., Kelley, K., Dunscomb, J., Perkins, A., Wang, Y., Beeler, C.,  & Boustani, M. (2019). Using the agile implementation model to reduce central line–associated bloodstream infections. American journal of infection control, 47(1), 33-37.

Bayode, M. T., Olalemi, A. O., & Oladejo, B. O. (2021). Multiple antibiotic resistant index and detection of qnrS and qnrB genes in bacterial consortium of urine samples from clinical settings. European Journal of Biological Research, 11(1), 45-56.

Chavan, A. R., & Kelkar, V. (2017). Study of healthcare-associated infections in surgical unit in a newly established tertiary care hospital of Nanded, Maharashtra, India. International Journal of Surgery Open, 9, 30-35.

Ciofi degli Atti, M., Bernaschi, P., Carletti, M., Luzzi, I., García-Fernández, A., Bertaina, A., & Raponi, M. (2014). An outbreak of extremely drug-resistant Pseudomonas aeruginosain a tertiary care pediatric hospital in Italy. BMC infectious diseases, 14(1), 1-8.

Edwardson, S., & Cairns, C. (2019). Nosocomial infections in the ICU. Anaesthesia & Intensive Care Medicine, 20(1), 14-18.

Gnass, M., Gielish, C., & Acosta-Gnass, S. (2014). Incidence of nosocomial hemodialysis-associated bloodstream infections at a county teaching hospital. American journal of infection control, 42(2), 182-184.

Greene, M. T., Saint, S., Ratz, D., Kuhn, L., Davis, J., Patel, P. K., & Rogers, M. A. (2019). Role of transfusions in the development of hospital-acquired urinary tract–related bloodstream infection among United States Veterans. American journal of infection control, 47(4), 381-386.

Irek, E. O., Amupitan, A. A., Aboderin, A. O., & Obadare, T. O. (2018). A systematic review of healthcare-associated infections in Africa: An antimicrobial resistance perspective. African journal of laboratory medicine, 7(2), 1-9.

Jain, M., Sharma, A., Sen, M. K., Rani, V., Gaind, R., & Suri, J. C. (2019). Phenotypic and molecular characterization of Acinetobacter baumannii isolates causing lower respiratory infections among ICU patients. Microbial pathogenesis, 128, 75-81.

Khan, H. A., Ahmad, A., & Mehboob, R. (2015). Nosocomial infections and their control strategies. Asian pacific journal of tropical biomedicine, 5(7), 509-514.

Khan, H. A., Baig, F. K., & Mehboob, R. (2017). Nosocomial infections: Epidemiology, prevention, control and surveillance. Asian Pacific Journal of Tropical Biomedicine, 7(5), 478-482.

Liang, S. Y., & Marschall, J. (2011). Commentary: Update on emerging infections: news from the Centers for Disease Control and Prevention. Annals of emergency medicine, 58(5), 450-451.

Md. Robeul Islam, Avijit Banik et al. (2024). Isolation, Identification, and Antibiotic Susceptibility Analysis of Bacterial Pathogens in Suspected Urinary Tract Infection Cases at a Tertiary Medical Center in Dhaka, Bangladesh, Journal of Primeasia, 4(1), 1-7, 40048

Nagao, M. (2013). A multicentre analysis of epidemiology of the nosocomial bloodstream infections in Japanese university hospitals. Clinical Microbiology and Infection, 19(9), 852-858.

Olalemi, A., Oladejo, B., & Bayode, M. (2021). Correlation between faecal indicator bacteria in diarrheagenic stools and hospital wastewaters: implication on public health. African Journal of Clinical and Experimental Microbiology, 22(2), 234-243.

Šuljagic, V., Cobeljic, M., Jankovic, S., Mirovic, V., Markovic-Denic, L., Romic, P., & Mikic, D. (2005). Nosocomial bloodstream infections in ICU and non-ICU patients. American journal of infection control, 33(6), 333-340.

Surgical site infections. Johns Hopkins Medicine. https://www.hopkinsmedicine.org/health/conditions-and-diseases/surgical-site-infections. Published November 22, 2019. Accessed September 8, 2022.

Venier, A. G., Lavigne, T., Jarno, P., L'heriteau, F., Coignard, B., Savey, A., & Rogues, A. M. (2012). Nosocomial urinary tract infection in the intensive care unit: when should Pseudomonas aeruginosa be suspected? Experience of the French national surveillance of nosocomial infections in the intensive care unit, Rea-Raisin. Clinical Microbiology and Infection, 18(1), E13-E15.

Zuo, M., Tang, J., Xiang, M., Long, Q., Dai, J., & Hu, X. (2018). Characteristics and factors associated with nosocomial pneumonia among patients undergoing continuous renal replacement therapy (CRRT): A case–control study. International Journal of Infectious Diseases, 68, 115-121.

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