The Carnivore Diet in Autoimmune Disease Management and Evaluating Benefits, Risks, and Personalized Nutritional Approaches
Md. Sohel Rana 1*
Australian Herbal Insight 8(1) 1-8 https://doi.org/10.25163/ahi.8110187
Submitted: 06 November 2024 Revised: 10 January 2025 Published: 14 January 2025
Abstract
Autoimmune diseases affect millions of individuals worldwide, causing chronic inflammation, pain, and debilitating symptoms. Conventional treatments often focus on suppressing the immune system, but dietary interventions have gained attention as alternative management strategies. The carnivore diet, which consists solely of animal-based foods while excluding all plant-derived foods, has emerged as a controversial approach for managing autoimmune conditions. Proponents claim that eliminating plant-based foods reduces exposure to potential dietary triggers, leading to lower inflammation and improved symptoms. Moreover, the diet's high nutrient density and lack of processed foods may provide additional benefits for autoimmune patients. However, concerns about the carnivore diet persist, particularly regarding long-term health risks and nutritional adequacy. Critics argue that the complete exclusion of fiber and plant-derived antioxidants may harm gut health, potentially worsening autoimmune conditions over time. Additionally, excessive consumption of saturated fats from animal sources raises concerns about cardiovascular disease and metabolic imbalances. The lack of diversity in food choices may also increase the risk of nutrient deficiencies, impacting overall health and immune function. This review article explores the pros and cons of the carnivore diet for autoimmune conditions, analyzing its potential benefits, risks, and mechanisms of action. By reviewing existing literature and anecdotal evidence, this discussion aims to provide a balanced perspective for individuals considering this dietary approach. While some autoimmune patients report significant improvements on a carnivore diet, others may experience adverse effects, highlighting the importance of personalized nutrition. Given the limited scientific research on the long-term effects of this diet, healthcare professionals should be involved in decision-making to ensure safety and nutritional adequacy. Ultimately, the carnivore diet presents both promising potential and serious risks, emphasizing the need for further research to determine its efficacy in autoimmune disease management. A personalized and well-monitored dietary approach may be the most sustainable path for individuals navigating autoimmune conditions.
Keywords: Carnivore diet, autoimmune diseases, inflammation, gut health, dietary intervention, nutrient deficiencies, chronic disease, metabolic health
References
Abdelhamid, A. S., et al. (2018). Omega-3 fatty acids for the primary and secondary prevention of cardiovascular disease. Cochrane Database of Systematic Reviews, 11, CD003177.https://doi.org/10.1002/14651858.CD003177.pub4
Biesiekierski, J. R., et al. (2010). Characterization of irritable bowel syndrome and gastrointestinal sensitivity in response to fermentable carbohydrates. Gastroenterology, 138(2), 512-519.
Brinkworth, G. D., et al. (2009). Long-term effects of a very-low-carbohydrate diet and a low-fat diet on mood and cognitive function. Archives of Internal Medicine, 169(20), 1873-1880.https://doi.org/10.1001/archinternmed.2009.329
Chiavolini, D. (2023, August 16). Culinary Medicine: Autoimmunity and Healthy Eating. Global Autoimmune Institute.
Cordain, L., et al. (2005). Origins and evolution of the Western diet: health implications for the 21st century. American Journal of Clinical Nutrition, 81(2), 341-354.https://doi.org/10.1093/ajcn.81.2.341
Davis, N. J., et al. (2009). Comparative study of the effects of a very-low-carbohydrate and a high-carbohydrate diet on mood and cognitive function. Obesity, 17(1), 57-63.
Feinman, R. D., & Fine, E. J. (2007). Nonequilibrium thermodynamics and energy efficiency in weight loss diets. Metabolic Syndrome and Related Disorders, 5(4), 319-322.https://doi.org/10.1186/1742-4682-4-27
Fung, T. T., et al. (2010). Low-carbohydrate diets and all-cause and cause-specific mortality. Annals of Internal Medicine, 153(5), 289-298.https://doi.org/10.7326/0003-4819-153-5-201009070-00003
Henderson, S. T. (2008). Ketone bodies as a therapeutic for Alzheimer's disease. Neurotherapeutics, 5(3), 470-480.https://doi.org/10.1016/j.nurt.2008.05.004
Johnston, C. S., et al. (2014). Comparison of weight loss among named diet programs in overweight and obese adults. JAMA, 312(9), 923-933.https://doi.org/10.1001/jama.2014.10397
Kahleova, H., et al. (2017). Vegetarian diets and glycemic control in diabetes: A systematic review and meta-analysis. Cardiovascular Diagnosis & Therapy, 7(4), 360-377.
Krebs, J. D., et al. (2019). The effect of a high-protein, low-carbohydrate diet on blood glucose control in people with type 2 diabetes. Diabetic Medicine, 36(8), 1005-1012.
Ludwig, D. S., et al. (2018). Dietary carbohydrates: Role of quality and quantity in chronic disease. BMJ, 361, k2340.https://doi.org/10.1136/bmj.k2340
Manninen, A. H. (2006). Very-low-carbohydrate diets and preservation of muscle mass. Nutrition & Metabolism, 3(1), 9.https://doi.org/10.1186/1743-7075-3-9
Mente, A., et al. (2017). Association of dietary nutrients with blood lipids and blood pressure in 18 countries. The Lancet, 90(10107), 2643-2656.
Miller, V., et al. (2020). Dietary patterns and all-cause mortality in 21 countries. European Heart Journal, 41(27), 2656-2667.
Mozaffarian, D., et al. (2011). Changes in diet and lifestyle and long-term weight gain in women and men. New England Journal of Medicine, 364(25), 2392-2404.https://doi.org/10.1056/NEJMoa1014296
Norwitz, N. (2025, February 10). Expert shatters myths about the trendy 'carnivore' diet-and the real impact it has on your health. New York Post.
Paoli, A., et al. (2013). Ketogenic diet in neuromuscular and neurodegenerative diseases. BioMed Research International, 2013, 1-10.https://doi.org/10.1155/2013/249398
Sacks, F. M., et al. (2009). Comparison of weight-loss diets with different compositions of fat, protein, and carbohydrates. New England Journal of Medicine, 360(9), 859-873.https://doi.org/10.1056/NEJMoa0804748
Samaha, F. F., et al. (2003). A low-carbohydrate as compared with a low-fat diet in severe obesity. New England Journal of Medicine, 348(21), 2074-2081.https://doi.org/10.1056/NEJMoa022637
Schwingshackl, L., et al. (2017). Food groups and risk of all-cause mortality: A systematic review and meta-analysis. American Journal of Clinical Nutrition, 105(6), 1462-1473.https://doi.org/10.3945/ajcn.117.153148
Shai, I., et al. (2008). Weight loss with a low-carbohydrate, Mediterranean, or low-fat diet. New England Journal of Medicine, 359(3), 229-241.https://doi.org/10.1056/NEJMoa0708681
Smith, S. R., et al. (2010). The effect of a high-protein, low-fat, and low-carbohydrate diet on weight loss and metabolism. American Journal of Clinical Nutrition, 91(2), 373-381.
Volek, J. S., et al. (2009). Carbohydrate restriction has a more favorable impact on the metabolic syndrome than a low-fat diet. Lipids, 44(4), 297-309.https://doi.org/10.1007/s11745-008-3274-2
Yancy, W. S., et al. (2004). A low-carbohydrate, ketogenic diet versus a low-fat diet to treat obesity and hyperlipidemia. Annals of Internal Medicine, 140(10), 769-777.https://doi.org/10.7326/0003-4819-140-10-200405180-00006
Zhao, Y., et al. (2015). Diet and inflammation: Food effects on gut microbial communities and immune function. Current Opinion in Clinical Nutrition & Metabolic Care, 18(4), 373-378.
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