Multidisciplinary research and review journal | Online ISSN 3064-9870
RESEARCH ARTICLE   (Open Access)

Isolation, Identification and Antibiotic Sensitivity Pattern of Salmonella typhi Isolated from Blood Samples of Patients in Dhaka City, Bangladesh

Mohammad Mizanur Rahman1, Maruf Abony1, Kaniz Fatema1, Suvamoy Datta1*

+ Author Affiliations

Journal of Primeasia 1(1) 1-5 https://doi.org/10.25163/primeasia.560014

Submitted: 11 October 2020  Revised: 05 December 2020  Published: 15 December 2020 

Abstract

In recent years, there has been a significant rise in the prevalence of multidrug resistance Salmonella typhi in Dhaka city. To study the prevalence rate and identification of typhoidal Salmonella typhi among the patients attending at a hospital by conventional test.  It was seen that 88% (Amoxyclave) of the S. typhi strains are resistant to the antibiotics used against them. Gentamycin, Levofloxacin and Meropenem (100% sensitive) are the best drugs for the treatment of S. typhi infection followed by Ciprofloxacin (99% sensitive). None of the samples exhibited sensitivity to more than four drugs. Typhoid fever occurs infrequently in developed counties but massively in developing countries. Traditionally the drugs of choice were chloramphenicol, ampicillin, and cotrimoxazole but unfortunately the emergence of multidrug resistant strains of S. typhi introduced the use of Amikacin, Imipenem & Netilmycin among the patients. However, now a day’s ciprofloxacin used frequently as a drug of choice but this study, isolated S. typhi are sensitive to ciprofloxacin 95 % that twisted the circumstances into different directions.

Keywords: Salmonella, Blood Samples, Antibiotic Sensitivity, Bangladesh.

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