Antibiotic Sensitivity Pattern of Staphylococcus aureus Isolated from Pus Samples of Different Age and Sex Groups in Gazipur District, Bangladesh

Md. Eaktear Uddin ¹, Shakila Sultana ¹, Maruf Abony ¹, Suvamoy Datta ^1*

S. aureus infections pose a global health threat with rising antibiotic resistance. Gentamycin emerges as a crucial treatment amidst multidrug resistance challenges.

Abstract

Staphylococcus aureus has long been reported as one of the most important bacteria that cause different kinds of diseases in humans, particularly skin and soft tissue infections such as abscesses (boils), furuncles, and cellulitis. To treat these infections, certain antibiotics have frequently been used across the world. However, nowadays, there is a growing concern on the treatment of staphylococcal infections due to gaining resistance to some antibiotics by this bacterium.  In the present work, S. aureus was isolated from 40 pus samples and a total of 40 isolates were selected to study their multi-drug resistance pattern using 10 available antibiotics. Among the antibiotics used, gentamycin was found to be the most effective to control S. aureus as the isolates showed minimum resistance to this antibiotic (0%). On the other hand, the isolates showed the highest resistance to amoxicillin (100%). Among 40 isolates, one isolate (2.5%) was resistant to the maximum number of antibiotics used in the experiments (seven), while five isolates (12.5%) showed resistance to maximum 6 antibiotics, and five isolates (12.5%) were resistant to at least 5 antibiotics. Overall, a total of 27.5% isolates were multi-drug resistant (resistant to 5 or more of the antibiotics tested). In conclusion, the findings of this study would be helpful to choose appropriate antibiotic for treating staphylococcal infections considering the multi-drug resistance of the bacterium.

Keywords: S. aureus, Pus samples, Gazipur city, Bangladesh,

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