This study highlights probiotics as a safe, holistic approach for restoring microbial balance, regulating hormones, and reducing inflammation in menstrual disorders.

This study highlights how traditionally fermented alcoholic beverages subtly influence gut microbiota, emphasizing balance between microbial benefits and alcohol-related risks.

This review clarifies how industrial processing diminishes yogurt’s probiotic quality and underscores the importance of authentic fermentation for true health benefits.

The study informs strategies to safeguard astronaut health and spacecraft integrity by understanding microbial adaptation in space.

This review discusses fungal-soil interactions enables strategies for sustainable agriculture, soil health improvement, biodiversity conservation, and climate change mitigation through enhanced ecosystem resilience.

This study determines lactic acid bacteria as eco-friendly probiotics that enhance soil, crop, and livestock health, promoting sustainable agricultural resilience.

This review highlights probiotics’ potential to naturally support mental well-being by clarifying how gut microbes influence mood, stress, and cognition.

This study clarifies how mRNA vaccines might briefly influence gut microbiome balance, guiding future research on vaccine safety, immunity, and microbial health.

This review highlights how antibiotic misuse in agriculture fuels global antimicrobial resistance, urging integrated health policies to prevent an impending crisis.

Mapping microbial and human genomic dark matter enables targeted therapeutics and sustainable biotechnological innovations.

The study underscores probiotics’ expanding therapeutic potential beyond gut health, highlighting innovations in psychobiotics, postbiotics, and personalized microbiome-based medicine.

Marine microbial metabolites offer diverse chemical scaffolds for novel therapeutics addressing antibiotic resistance and emerging diseases.

This study reveals marine microorganisms as scalable, diverse bioactive sources while highlighting the urgent need for standardized, integrative discovery frameworks.

Clarifies how microalgal diversity underpins scalable bioindustrial performance, guiding evidence-based strain selection, process optimization, and sustainable biotechnology deployment worldwide development.

Understanding plant microbiomes enables sustainable, eco-friendly strategies for crop protection and productivity enhancement.

This study integrates ecological and human health evidence, clarifying how microcystins move through agricultural systems and influence environmental and public health risks.

Understanding hvAB mechanisms informs treatment strategies and guides development of targeted interventions against multidrug-resistant, hypervirulent pathogens.

Blockchain-based traceability strengthens trust, safety, and sustainability across complex value chains through transparent, immutable, and data-driven governance systems.

Marine-derived bioactive compounds offer sustainable, effective alternatives to chemical algicides and antimicrobial agents with minimal ecological impact.

Marine microbiomes offer a statistically validated and underexplored pathway for accelerating bioactive compound discovery through genome-enabled strategies.

This study reveals how extreme-environment microbes bridge ecological adaptation and biotechnology, offering new directions for drug discovery and sustainable innovation.

Targeting polymicrobial oral biofilms with novel natural and engineered therapies offers sustainable solutions against escalating antimicrobial resistance.

This review demonstrates sustainable enzyme production from agro-industrial waste via solid-state fermentation, advancing circular bioeconomy, waste valorization, and eco-friendly bioremediation technologies.

This study demonstrates that microbiome restoration is central to preventing Clostridioides difficile recurrence and improving sustainable treatment outcomes.

Understanding microalgal metabolite responses aids sustainable biotechnology and environmental adaptation strategies.

Understanding fungal diversity supports sustainable agriculture, human nutrition, and the development of innovative biotechnological applications.

Harnessing microbial biosynthetic diversity provides sustainable pathways for discovering novel bioactive compounds with pharmaceutical and industrial applications.

This review clarifies how structurally diverse natural products selectively target cancer cells and microbial virulence pathways absent in humans.

Provides a comprehensive roadmap for novel antimicrobial strategies to combat multidrug-resistant infections and improve patient outcomes.

Integrating novel targets, advanced technologies, and underexplored ecosystems is essential to overcome antimicrobial resistance and revive antibiotic discovery.

This review highlights aromatic polyketides as scalable, genome-enabled solutions for overcoming antimicrobial resistance and revitalizing antibiotic discovery pipelines.

Marine cyanobacteria and beneficial microbes provide eco-friendly solutions for agriculture, biotechnology, and sustainable industrial applications.

The systematic exploration of bioactive secondary metabolites (SMs) holds critical significance for medicine, agriculture, and biotechnology. These metabolites represent a treasure trove of structurally diverse molecules with the potential to address urgent global health challenges,

Marine actinobacteria offer resistance-aware, microbiome-friendly therapeutic pathways to address acne vulgaris amid rising antibiotic failure.

Understanding microbe-mediated predator–prey interactions enables sustainable soil pest management and resilient agroecosystems.

This study highlights critical fungal health risks, informing public health strategies and guiding future research to mitigate exposure globally.

This study provides quantitative evidence linking enzyme function and marine diversity to enhanced carotenoid yields, guiding targeted metabolic engineering strategies for industry.

This study clarifies how fungal metabolomic diversity simultaneously drives nutritional benefits and toxic risks, guiding safer consumption and targeted functional food development.

This study, integrating thermodynamic principles, metabolic engineering, and microbial consortia, provides innovative strategies to enhance microbial biofuel productivity and sustainability.

Integrating natural bioactives and repurposed drugs offers promising, resistance-aware therapeutic strategies for respiratory diseases and multidrug-resistant infections.

This study integrates sustainability and microbiome science, proposing yeast-based nanotechnology as a biocompatible strategy to address early-life antimicrobial resistance challenges.

Insect gut microbiomes degrade plastics within hours, offering transformative enzymatic solutions to global polymer pollution that conventional methods cannot achieve.

This study reveals mechanistic–efficacy gaps and resistance nuances in iChip-derived antibiotics, guiding future antibiotic design beyond conventional discovery paradigms.

This review highlights microbial metabolites as critical immunometabolic drivers of chronic cystic fibrosis lung inflammation and therapeutic resistance.

Understanding microbial dynamics reveals how oral and systemic microbial shifts drive disease, guiding preventive and therapeutic microbiome-targeted strategies.

Bacterial pneumonia shows a distinct glucose and urea signature, suggesting biochemical monitoring should accompany microbiological diagnosis in routine clinical care.

Links hMPV infection to glycemic and IL-17 disruption, suggesting a previously unrecognized viral contributor to Type 2 diabetes risk.

Engineered probiotic consortia reprogram gut ecology with molecular precision, offering safer, durable alternatives to antibiotics for infectious and metabolic disease.

Linking multi-omics profiling with AI-guided bioactive design offers a reproducible, equitable route from raw microbiome data to personalized clinical therapeutics.

Probiotics can unintentionally spread antimicrobial resistance genes; genomic screening and CRISPR-based safeguards are essential before clinical or agricultural deployment.Pages: 1-8

Genomic and diagnostic tools may offer a faster, more sensitive route to detecting and countering last-resort antibiotic resistance worldwide.

Reveals synergistic microbiome–nutrient mechanisms reducing cadmium toxicity, offering scalable, sustainable strategies to improve crop safety, resilience, and productivity globally.

Reveals how reclaimed water reshapes soil resistomes, linking agriculture, microbiomes, and public health through a One Health systems perspective.

The systematic exploration of bioactive secondary metabolites (SMs) holds critical significance for medicine, agriculture, and biotechnology. These metabolites represent a treasure trove of structurally diverse molecules with the potential to address urgent global health challenges,

This study integrates biomedical and ecological research, revealing shared biological mechanisms that inform therapeutic innovation, sustainable agriculture, and systems-level understanding of complex biological interactions.