Integrative Biomedical Research
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Integrative Biomedical Research
Integrative Biomedical Research is an, international, peer-reviewed, Open Access journal that publishes research articles in following topics:
- Molecular & Cellular Biomedicine
- Pharmacology & Drug Discovery
- Clinical & Translational Medic
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Integrative Biomedical Research
Table of Contents
Communications
Public Health & Epidemiology
Qurratul Aini 1*
The My-Stress application aids hospitals in proactively managing employee stress, enhancing well-being, and optimizing organizational effectiveness.
Abstract | Full Text |PDF (491 KB) | Open Access Article
Research Article
Public Health & Epidemiology
Factors Influencing Pulmonary Tuberculosis Incidence in Banggai Laut
Muhammad Irwan Rizali1*, Nur Nasry Noor1, Ida Leida Maria1, Andi Arsunan Arsin1, Apik Indarty Moedjiono2
This study identifies factors influencing TB distribution in Banggai Laut, offering insights for targeted interventions to improve public health outcomes.
Abstract | Full Text |PDF (653 KB) | Open Access Article
Prevalence and Risk Factors of Hypertension in Adolescents
Andi Alifah Aulya Sultan1*, Andi Zulkifli2, Ridwan Amiruddin2, Healthy Hidayanty3, Suriah4
This study determines hypertension prevalence and associated risk factors in Indonesian adolescents, crucial for targeted public health interventions.
Abstract | Full Text |PDF (1 MB) | Open Access Article
Bandr Fakiha 1*
This study emphasizes the need for preventive measures, caregiver education, and improved healthcare systems to reduce pediatric poisoning incidents.
Abstract | Full Text |PDF (288 KB) | Open Access Article
Knowledge in Enhancing Antenatal Care Compliance and Improving Maternal and Neonatal Health Outcomes
Fajar Sari Tanberika 1,2 *, Tukimin Bin Sansuwito 3, Hafizah Che Hassan 4
This study provides the understanding how knowledge influences antenatal care compliance can enhance health education strategies and improve maternal and neonatal health outcomes.
Abstract | Full Text |PDF (190 KB) | Open Access Article
Mohammed a.m.y. Al-Hetar1,2,4, Husni al-Goshae3, Norasyikin a. Wahab1, Mahfoudh A.M. abdulghani3, Abdullah y. Al-Mahdi3, Mohamad Faez Baobaid3, Abdullah Mohammed al-matary4, Qais m. Al-hetar2, Mohammed e. Alezzy2, Dya'a alhaq senan2, Sakina Ruhi3
This study determined critical gender and age disparities in vitamin D deficiency, emphasizing targeted interventions for public health improvement.
Abstract | Full Text |PDF (303 KB) | Open Access Article
Sakina Ruhi1*, Develgah Thirunana Sambantham1, Ayesha syed1, Salman K3, ,Bushra Gohar Shah1, Sohayla M. Attalla1 , Husni Ahmed Al Gosha1, Atika Farooqui5 , Jiyauddin khan2 , Ram Kumar Sahu4, Mohammad Khusni1
This study demonstrates moderate colon cancer knowledge and emphasizes improving public education and preventive strategies for lifestyle-related risk factors.
Abstract | Full Text |PDF (270 KB) | Open Access Article
Healthcare Determinants and Dominant Factors of Maternal Mortality Ratio
Nursuciyani Jamal1*, Muhammad Alwy Arifin2, Muhammad Yusran Amir2, Sukri Palutturi2, Atjo Wahyu3
This study determined the critical factors like accessibility, affordability, and birth practices affecting maternal mortality, emphasizing targeted interventions for prevention.
Abstract | Full Text |PDF (348 KB) | Open Access Article
Fahimeh Feili 1, Mohamadali Roozegar 1*
This study underscores insufficient oral cancer knowledge in Iran, highlighting the need for tailored educational interventions to enhance health literacy.
Abstract | Full Text |PDF (277 KB) | Open Access Article
Silvia Nora Anggraini1, Faridah Mohd Said1, Awaliyah Ulfah Ayudyhta Edzha1, Dwi Elka Fitri1, Isna Ovari1, Fitra Wahyuni2, Iftiana3*
This review discusses the lifestyle factors can guide interventions to reduce hypertension risk in elderly populations, improving public health outcomes.
Abstract | Full Text |PDF (173 KB) | Open Access Article
Risk Factors for Mycobacterium Tuberculosis Infection Among HIV/AIDS Populations in China
Zhao Junpeng1,2,3, Richard Avoi1*, Azman Bin Atil Azmi1, Zheng Baiqin2, Wang Lei2, Qiang Rundong2, Cao Huihui2, Gao Weilin2, Zhang Xu2, Du Ruihuan2, Yao Yuhong4, Qi Wenjie4, Wang Lifang5
This study identified key factors influencing MTB infection risk in HIV/AIDS patients in Hebei, guiding effective TB prevention strategies.
Abstract | Full Text |PDF (217 KB) | Open Access Article
Impact of Work Climate, Workload, and Stress on Fatigue for Improving Health and Work Outcomes
Pratiwi Fuji Lestari1*, Masyitha Muis2, Yahya Thamrin2, Furqaan Naiem2, Lalu Muhammad Saleh2, Muhammad Alwy Arifin3
This study determined the critical relationship between workplace conditions, fatigue, and productivity, emphasizing the need for improved working environments to enhance employee well-being.
Abstract | Full Text |PDF (181 KB) | Open Access Article
Birendra Kumar Sahu 1*, Kishor Kumar Sahu 1
This research demonstrates urgent disparities in cardiovascular health among Medicare beneficiaries, emphasizing the need for targeted interventions in vulnerable communities.
Abstract | Full Text |PDF (186 KB) | Open Access Article
Impact of Multi-Component Outreach on Colorectal Cancer Screening and Genetic Testing Preferences
Sanjay Kumar Mire 1*, Varri Srinivasa Rao 1
This study elucidates the critical role of outreach strategies in increasing colorectal cancer screening and genetic testing participation.
Abstract | Full Text |PDF (352 KB) | Open Access Article
Deepak Kumar Sahu 1*, Himanshu Nirmal Chandu 1
This study determined the critical role of clinical pharmacists in reducing cardiovascular disease risk factors, improving patient outcomes through community-based interventions.
Abstract | Full Text |PDF (475 KB) | Open Access Article
Mohammed A. Abdalqader1*, Hana Chen2*, Norhafizah Ab Manan1, Abd Rahim Mohamad1, Krishna Gopal Rampal1, Thein Win Naing1, Alabed Ali A. Alabed1, Mohamad Zulkipli Bin Othman1, Ahmad Nizal Bin Mohd Ghazali1, Hooi Chia Tang3, Jegathambigai Rameshwar Naidu2, Hasanain Faisal Ghazi4
This research provides valuable insights into the sociodemographic factors influencing knowledge, attitudes, and practices, offering a basis for targeted public health interventions aimed at reducing the burden of heart attacks in the region.
Abstract | Full Text |PDF (359 KB) | Open Access Article
Sabaa Muhsen Farhan 1*, Yasmin Ammar Adi 2, Zaid Khalid Alani 3, Jihad Talib Obead Al-Yasari 4,5, Hayder Musaad Al-Timimi 6
This study emphasized the effectiveness of PCR in detecting Toxoplasma gondii infections, especially in pregnant women, for improving public health.
Abstract | Full Text |PDF (176 KB) | Open Access Article
Aram Dawood Abbas 1*
This study demonstrated a practical method to enhance drinking water quality, potentially reducing health risks associated with unsafe water.
Abstract | Full Text |PDF (303 KB) | Open Access Article
Md Fokhrul Islam 1, Shusmoy Debnath 2, Himal Das 3, Fuad Hasan 4, Sanjida Sultana 5, Rubel Datta 6, Bilash Mallik 7, Md. Halimuzzaman 8
This study showed how economic growth, CO2 emissions, urbanization, and natural resource use impact healthcare spending in Bangladesh, offering insights for policy development.
Abstract | Full Text |PDF (405 KB) | Open Access Article
Global Trends in Key Hospital Performance Indicators: A Decade of Research Insights (2014-2023)
Ilham Hariyadi 1* , Qurratul Aini 1
This study determined global research trends on hospital KPIs, highlighting publication patterns, key contributors, and emerging focus areas.
Abstract | Full Text |PDF (1 MB) | Open Access Article
Mukhitdinov Shavkat Mukhammedzhanovich 1*, Dilmurod Davronovich Aliyev 2, Ismailov Kamil Tuygunovich 3, Ochilov Behzod Salimovich 4, Avazov Otabek Safarali Ugli 5
This study revealed the critical role of ecological adaptation in enhancing immune function and lamb viability in diverse environments.
Abstract | Full Text |PDF (195 KB) | Open Access Article
Women Health, Empowerment and Its Association with Contraceptive Use
Md. Amanat Ullah 1, 2, S. M. Mostafa Kamal 3, Rokeya Begum 4, Tanzillah Wahid 5
Empowering women reduces gender inequality, increases their independence, and encourages the use of modern contraceptives among married women in Bangladesh.
Abstract | Full Text |PDF (435 KB) | Open Access Article
A Clinical Analysis of Measles Outbreak and Immunization Gaps
Gulnora A. Arashova 1*
This study showed the immunization gaps and clinical severity, and an urgent need for better vaccination strategy for measles cases.
Abstract | Full Text |PDF (229 KB) | Open Access Article
Abdulsalam Harfash Hassan 1*, Abeer Th.kadhim 1
This study determined the demographic patterns (gender, age, residency, occupation) and anatomical distribution of hydatid cysts, crucial for targeted public health interventions in endemic areas.
Abstract | Full Text |PDF (163 KB) | Open Access Article
COVID-19's Ripple Effect: Transforming Academic Supervision and Learning for Dental Students
Amal Mohammed Sindi 1*
Understanding student experiences with remote learning during COVID-19 highlights necessary improvements for academic advising and support systems in dental education.
Abstract | Full Text |PDF (539 KB) | Open Access Article
Maternal Age, Nutrition, and Pregnancy Count Impact Gestational Hypertension
Rifatolistia Tampubolon 1*, Kristiani Desimina Tauho 1, Maya Miranthi Oematan 1
This study showed factors affecting gestational hypertension to improve maternal health outcomes in a high-risk Indonesian province.
Abstract | Full Text |PDF (198 KB) | Open Access Article
Anita Widi Hastuti 1*, Qurrotul Aini 1
This study showed how enhancing organizational climate, managing workload, and implementing patient-centered care improve nursing service quality.
Abstract | Full Text |PDF (180 KB) | Open Access Article
Leadership Styles in healthcare settings for Hospital Management and Employee Engagement
Qurratul Aini1* Nur Rachman Dzakiyullah 2
Effective leadership in hospital administration crucially shapes organizational culture, boosts employee engagement, and enhances patient care quality in Indonesia.
Abstract | Full Text |PDF (265 KB) | Open Access Article
Midwives, Nurses Crucial for Disaster-Resilient Maternal Care and Preparedness Strategies
Lenny Stia Pusporini 1*, Putri Wulandini S 2, Wulan Novika Ambarsari 3, Nurul Qamarya 4 Loso Judijanto 5, Eny Retna Ambarwati 6, Ade Herman Surya Direja 7, Karwati 3, Tria Nopi Herdiani 7
Disaster resilience strategies by midwives and nurses significantly enhance maternal care outcomes during emergencies in Indonesia.
Abstract | Full Text |PDF (272 KB) | Open Access Article
Health Risk from Heavy Metal Contamination in Maize
Adnan. Al-Trbany 1,2*, Ali H. Elsayed.2, Abd El-Hakim A. Fawzy. 2, Mona A. Khorshed 1
Heavy metal contamination in maize threatens global food safety, potentially causing severe health issues and necessitating stringent regulatory measures to protect public health and agriculture.
Abstract | Full Text |PDF (581 KB) | Open Access Article
Healthcare Service Quality Digitization with Enterprise Resource Planning
Md. Halimuzzaman1*, Jaideep Sharma2, Mohammed Imam Hossain3, Fahmida Akand4, Md Nahidul Islam5, Mostafa Masrur Ikram6, Nusrat Neherin Khan7
This study showed healthcare service quality by leveraging ERP systems for streamlined operations, improved patient care, and operational efficiency.
Abstract | Full Text |PDF (386 KB) | Open Access Article
Safa Azhar Razzaq 1*
The study found that there was relationship between vitamin D levels and BMI values in female.
Abstract | Full Text |PDF (253 KB) | Open Access Article
A Rapid Diagnosis Development of Canine Enteric Coronavirus Inflammation
Mohammed Ali Hussein 1,2*, Mawlood Abbas Ali Al-Graibawi 1
This study elucidated the prevalence of CECoV in Baghdad, Iraq, highlighting its zoonotic potential and emphasizing the importance of surveillance and diagnostic tools.
Abstract | Full Text |PDF (284 KB) | Open Access Article
Real-Time PCR Diagnosis of COVID-19 in Al Anbar Province, Iraq
Mohammed A. Hamad 1*, Firas R. Jameel 1, Noor Najm Abdullah 1, Muhaidi MJ 2
Accurate diagnosis with real-time PCR is essential for pandemic control. Understanding transmission dynamics aids in formulating effective public health measures.
Abstract | Full Text |PDF (583 KB) | Open Access Article
Rusul Hazim Al-darajee 1*, Masarat S. Al-Mayahi 1
The study on goat uterine morphology and histology offers insights into reproductive health and breeding management for sustainable agriculture.
Abstract | Full Text |PDF (2 MB) | Open Access Article
Nutritional Evaluation of Cassava Meal Components and Maize in Securing Feed and Food
Shahabuddin Ahmed1,2, Mrityunjoy Biswas2*, Atiqur Rahman Sunny3, Farhana Irin4, Md Faruk Hossain5, Md Mostafizur Rahman5, Md Abu Bakar Siddique5, Md. Alauddin 6, Mrinal Kanti Debnath2, Md. Pallo Hossain2, Tufael3, 7
This study determined the nutritional composition of cassava and maize, pivotal crops for food and animal feed production globally, offering insights into dietary recommendations, agricultural practices, and food security measures in regions reliant on these staples.
Abstract | Full Text |PDF (305 KB) | Open Access Article
Advances in Peer Teaching Methods in the Skill and Physical Development
Sura Gasid Hasan 1*
The study showed an innovative education for modern needs, improving basketball skills via peer teaching. Diverse methods motivate learners, enhancing health outcomes.
Abstract | Full Text |PDF (178 KB) | Open Access Article
Elytrigia Repens Extracts Control Urban Mosquito Vectors with a Larvicidal Potential
Prakash D 1*, Mohideen Abdulkader M 1, Sakthivel D 1, Manju I 1, Sreenivasan K S 1, Manikandan S 2
This study demonstrated larvicidal activity to prevent mosquito disease and its spread, which might be due to insecticidal phytocompounds in the extract.
Abstract | Full Text |PDF (307 KB) | Open Access Article
Simulation and Modeling of Water Treatment Plant with GPS-X Software for Health and Water Quality
Nabaa Abdul- Kareem 1*, Jabbar H. Al-Baidhani 1
This research determined the quality of the Water Treatment Plant using special software that verified the function of water treatment plants to ensure health safety.
Abstract | Full Text |PDF (920 KB) | Open Access Article
Saad Bader Abbas 1*, Rihab Al-Bedoui Bin Salem 2*
Research on health service satisfaction highlights vital insights for improving care, enhancing patient well-being, and optimizing resource utilization for better outcomes.
Abstract | Full Text |PDF (274 KB) | Open Access Article
A Retrospective Study of Outbreak and Vaccination on Measles Inflammation
Hayder Sudan Abbas Obaid 1, Ali Jaafar Mohammed 1, Laith A.I.K. Al-Kaif 2, *, Doaa Adil Abood 3, Younis A.K. Al-Khafaji 4
Understanding risk factors, vaccination rates, and surveillance effectiveness is crucial for developing targeted strategies to prevent measles infections in Iraq.
Abstract | Full Text |PDF (286 KB) | Open Access Article
Sakina Ruhi 1*, Adlina Abdullatif 1, Jegathambigai R. Naidu 1, Hana Chen 1, Ayesha Syed 1, Danish Saud khan 2, Husni Ahmed Al Gosha 1, Sohayla Mohamed Elsherbini A 1, Mya Mya Thwin 1, Thin Thin Aung 1
This study sheds light on the important role that education and awareness play in overcoming vaccine hesitancy in Malaysia.
Abstract | Full Text |PDF (1 MB) | Open Access Article
Reem Mohammed Abdel Wahhab 1*
This study showed an improved exercise enhancing kinetic response, vital for fencing to optimize athletes' and their healthy performance.
Abstract | Full Text |PDF (208 KB) | Open Access Article
Ahmed Saadi khlaf 1*, Asif Hasan Abdulrazaq 2, Nawar Bahaa Abdulsahib 3, Manaf Akram Ismaell 3, Mustafa Asif Hasan 3
Investigating Hepatitis B and C in Fallujah revealed higher prevalence among males, aiding targeted interventions and public health initiatives.
Abstract | Full Text |PDF (251 KB) | Open Access Article
Mohammed Qassim Baktash 1* , Ali Ismael Sulaiman 1
Understanding hypertension in Telafer City adults is vital for preventing problems, guiding interventions, and managing the disease effectively
Abstract | Full Text |PDF (294 KB) | Open Access Article
Huda Azhar Fadel 1*, Lekaa Hussein Khdaim 1
Iraqi date core-derived activated carbon effectively removes acetamiprid pesticide, crucial for combating water pollution, supported by comprehensive adsorption studies.
Abstract | Full Text |PDF (551 KB) | Open Access Article
Black Soldier Fly Larvae Feed with Fermented Bamboo Culms Enriched with Lactic Acid Bacteria
Nurul Azila Abdul Razak 1, Ang Chung Huap 1*, Vivien Jong Yi Mian 1, Siti Nor Ain Seri Masran 2
The study of plant-based protein source as the nutrition of Black soldier fly
Abstract | Full Text |PDF (758 KB) | Open Access Article
Analysis of Semi-Rural and Urban Hypertension Prevalence Using WHO Measures
Sumit Kumar Agrawal 1, Tripti Dewangan 2
Guiding a tailored intervention and strategy to advance global hypertension management
Abstract | Full Text |PDF (1 MB) | Open Access Article
Nazia Mahmud Badhon 1*
This study highlights herbal medicine’s role in chronic disease management, informing policy, integration strategies, and equitable healthcare access in Bangladesh.
Abstract | Full Text |PDF (211 KB) | Open Access Article
Umezurike Kingsley Chimuanya1, Chukwuma Oluchukwu Mariagoretti1,2, Ochiabuto Mary Barbara1, Manafa Patrick Onochie1, Ntum Ifeanyichukwu Michael1, Chukwuma George Okechukwu1,2
LF-specific IgG seroprevalence among inhabitants of river banks in Anambra State, Nigeria
Abstract | Full Text |PDF (292 KB) | Open Access Article
Assessing Knowledge Gaps on Diabetes Prevention Among Biology Graduates: A Study in Pondicherry
Samyuktha P 1, Pugazharasan 1*, Kuberan 1
This study determined critical gaps in preventive diabetes knowledge among biology graduates, highlighting the need for improved educational strategies on root causes and prevention.
Abstract | Full Text |PDF (138 KB) | Open Access Article
Reviews
Public Health & Epidemiology
Multimorbidity in Ageing Populations: Redefining Clinical Guidelines for Combined Disease Management
Ahmed Saadi khlaf 1*, Asif Hasan Abdulrazaq 2, Nawar Bahaa Abdulsahib 3,
Frailty-based, mechanism-anchored prescribing frameworks could replace single-disease guidelines that quietly harm complex older patients.
Abstract | Full Text | Open Access Article
Md. Maniruzzaman1, Md. Rakib Rased Rana2, Md Mizan3, Md. Sakibul Hasan4, Md. Nasim 4, Saiful Islam3, Jannatul Ferdush Easha mony3, Farjana Akter Shimo3, Miss Nuzhat Tasnim2, Md Nahid Hasan2
This study highlights post-pandemic roles of Bangladeshi pharmacists, emphasizing their evolving contributions to healthcare access, management, and therapeutic decision-making.
Abstract | Full Text |PDF (272 KB) | Open Access Article
Effects of Physical Activity as A Treatment For Depression in the Elderly
José Vinicius Bulhões da Silva 1, Weslley Barbosa Sales 2, Natália Herculano Paz 3, Annicia Lins Freitas1, Natália Mota da Silva Borges 1, Andrea Carla Brandão da Costa Santos 3, Eduardo Eriko Tenório de França1, Pollyana Soares de Abreu Morais 3, José Heriston de Morais Lima 1
Identifying effective physical activities for elderly depression supports holistic, low-cost, evidence-based interventions that enhance mental health and healthy aging.
Abstract | Full Text |PDF (399 KB) | Open Access Article
Sanad Shujaaa Alanzi 1, Sulaiman Mohammed Abdullah Almayouf 1, Khaled Mohamed Nahil Alotaibi 2, Amer Obelk Attya Alanazi 2, Alsahli, Hassan Ghuwayzi 3, Omar Nashmi Alharbi 1, Obaid Hamlan Obaid Aldajani 1
This review highlights global CVD disparities, identifies major risk factors, and evaluates effective, cost-efficient prevention strategies for population health.
Abstract | Full Text |PDF (358 KB) | Open Access Article
Wastewater Treatment and Reuse: Preventive Measures for Chronic Infectious Diseases
M A S Ansari 1, Md. Jahidul Islam 2, Md. Rafsan Jany 3, Fahmida Nargis 4, Anamika 5, Md. Nayem Hossain 6, Md. Mosharaf Hosen 6, Rakibul Hasan 2, Md. Asif 2, Arafat Chowdhury 7, Fatima Mazid Kona 8, Atiqur Rahman Sunny 9*
This review discusses the significance of wastewater treatment in sustainability, water security, environmental preservation, human health safeguarding and resource recovery.
Abstract | Full Text |PDF (1 MB) | Open Access Article
Asma Tabassum Happy1, Md Imran Hossain1, Rafiqul Islam2, Mohammad Shoriful Hossan Shohel1, Md Mozammel Haque Jasem3, Shown Ahmed Faysal1, MD Faisal Bin Shaikat1, Atiqur Rahman Sunny4*
This study emphasises how renewable energy enhances pharmacological logistics, clinical service continuity, and health outcomes in rural, disadvantaged healthcare systems.
Abstract | Full Text |PDF (238 KB) | Open Access Article
Mahmudul Hasan Mithun1, Md. Faisal Bin Shaikat2, Sharif Ahmed Sazzad3, Masum Billah4, Sadeques Salehin3, Al Maksud Foysal3, Arafath Jubayer 3, Rakibul Islam6, Asif Anzum7, Atiqur Rahman Sunny3*
This study provides microplastics' pervasive ecological and health risks, emphasizing bioaccumulation, biodiversity threats, and challenges in pollution management.
Abstract | Full Text |PDF (360 KB) | Open Access Article
Fahimeh Feili1,2, Mohamad Ali Roozegar 1,2*, Aminollah Vasigh3
This study determined the high prevalence of musculoskeletal disorders among dental students in Iran, urging the need for preventive ergonomic interventions.
Abstract | Full Text |PDF (176 KB) | Open Access Article
Balisa Mosisa Ejeta1*, Malay K Das 1, Sanjoy Das 1
This analysis is crucial for identifying barriers to oral contraceptive use, enhancing effectiveness, and improving reproductive health outcomes for diverse populations.
Abstract | Full Text |PDF (158 KB) | Open Access Article
Tareq Ali Suliman Alsalloom 1*, Abdulmalik Hmoud Alsuwayh 1, Khaled Mesfer B. Alsubaie 1, Mohammed Abdullah M. Altuwayjiri 1, Omar Wuqayyan O. Al Luhayan 1, Faisal Mubarak Mutani Al-Harbi 1, Sultan Radhi S. Alanazi 1, Farhan Aldowy A. Alanazi 1, Mohammed Salim A. Al Shalawi 1, Talal Alhumidi F. Alharbi 1, Mohammed Hamad Almutairi 1, Yousef Salman Alsubhi 1, Abdullah Mukhlef J. Alanazi 1, Abdullah Ghazi Al Suqmi Alruwaili 1
Integrating food waste reduction with nutrition in public institutions fosters health equity, sustainability, and effective resource stewardship through evidence-based interventions.
Abstract | Full Text |PDF (310 KB) | Open Access Article
Naif Faisal Bejad Albaqami 1*, Hamoud Fahad Hassan Alqahtani 1, Mohammed Fahad Hassan Alqahtani 1, Fahad Saad Fahad Alanazi 1, Wajb Ayed Aedh Al Otaibi 1, Fawaz Shujaa Fudghush Alharthi 1, Abdulmajeed Abdullah Alkhaibari 1, Ali Jamal Faleh Al-Anzi 1, Jameela Ahmed Alshehri 1, Adel Awad Al Rashedi 1, Yahy Ali A Majrashi 1, Meshari Bader F Alharbi 1, Mohsen Mohammed M Alkhidhran 1
Clarifies how mental health social workers maintain rights-based identities while navigating biomedical dominance, statutory constraints, and evolving interdisciplinary dynamics.
Abstract | Full Text |PDF (582 KB) | Open Access Article
Masoud Aedh Alqahtani 1*, Ali Mushabbab Alshahrani 1, Ahmed Mohammed Haqawi 1, Waleed Abdullah Alghamdi 1, Abdullah Ali Bin Jabr 1, Abdullah Mohammed Ghaythan Alqarni 1, Khalid Nasser K Alqahtani 1, Ghadyan Salem Alshammari 1, Muteb Freeh Saleman Alshammari 1, Moteb Rshid Aswi Alshamarimo 1, Sultan Faris Rasheed Alshammari 1, Sharif Owaidh T. Almutairi 1, Hamad Khalid Saleh Alfunayyikh 1, Tareq Ali Suliman Alsalloom 1, Abdulmalik Hmoud Alsuwayh 1, Khaled Mesfer B Alsubaie 1
This review analyzes how ultra-processed foods elevate NCD risks and emphasizes urgent regulatory, educational, and policy measures for global health equity.
Abstract | Full Text |PDF (312 KB) | Open Access Article
Sami Abdullah Al Mutairi 1*, Fayez Abdullah Hussain Alsuraimi 1, Sawsan Ahmad Ghassap 1, Nahil Ibrahim Alrawi 1, Ibrahim Muhammad Al-Arej 1, Hathal Fahad Ali Alsubaie 1, Magliah, Rami Fawzi 1, Saad Alwan Alshehri 1, Nawaf Aqeel Bin Nujaifan 1, Waleed Hussin Khubrani 1, Saleh Fayez Saleh Alfayez 1, Khalid Muflih Alanazi 1, Hassan Duairam Thawab Al-Shahrani 1
Robust, interconnected surveillance systems are essential for early detection and control of zoonotic outbreaks, protecting global health through One Health.
Abstract | Full Text |PDF (254 KB) | Open Access Article
Abdullah Mohammed Ghaythan Alqarni 1*, Sharif Owaidh T. Almutairi 1, Saad Abdulrazaq Ahmed Hayjan 1, Abdulaziz Mbark A. Al Hamdan 1, Taleb Ghazi Thaar Aldalbahi 1, Ahmed Sarhan Khalaf Alanazi 1, Abdulaziz Awad Dahrim Al Harbi 1, Hamad Saleh Alotaysh 1, Mohammed Saad Alasfour 1, Arwa Khalid Aldossari 1, Ali Owaid B. Alanazi 1, Nawaf Fahad Ali Alqahtani 1, Ibrahim Mohammed Al-Arij 1, Meshal Ibrahim Zaid Al Owias 1, Abdullaziz Fahad Abdullah Alwanais 1
This review highlights how climate change intensifies emergency health burdens and stresses the need for clinical, systemic, and policy responses to improve preparedness, equity, and resilience.
Abstract | Full Text |PDF (370 KB) | Open Access Article
Md Shahriar Abdullah 1, Md. Jahidul Islam 2, Md Mahadi Hasan 2, Dilip Sarkar 3, Md Sohel Rana 4*, Shib Shankar Das 5, Moazzam Hossian 6
This review discusses the direct correlation between inadequate waste disposal and increased dengue transmission, urging sustainable waste management to curb mosquito breeding.
Abstract | Full Text |PDF (746 KB) | Open Access Article
Wahyu Widodo 1*, Faridah Binti Mohd Said 2, Musheer 2
Evaluating mobile Health Belief Model applications can enhance diabetes care by improving patient knowledge, adherence, and preventing complications.
Abstract | Full Text |PDF (162 KB) | Open Access Article
Understanding Infectious Diseases: Prevention, Management, and Emerging Challenges
Badr Rashd Alrashedi 1*, Sari Mabrook Alrasheedi 1, Eman Smair Alanazi 1, Fatmah Malfi Altalouhi 1, Samar Saad Alotaibi 1, Tariq Mohammed Ruwayshid Alrehaili 1, Fahad Farej F. Alshammari 1, Badr Rashd Alrashedi 1, Abdullah Saleh Alshowmer 1, Abdullah Sabih Alanazi 1, Hamad Wazi Mulhi Alqahtani 1, Meshaal Ibrahim Al Owais 1, Adel Awadh Alrasheedi 1, Naser Algareesh 1, Sultan Khalifah Mabruk Almutairi 1, Mohammed Saeed Saleh Al Qahtani 1
This study provides a comprehensive understanding of infectious diseases, emphasizing prevention, early detection, and strategies to reduce global health burdens.
Abstract | Full Text |PDF (427 KB) | Open Access Article
Fahdah Mehsan Alotaibi 1*, Faisal Barjas AlHarbi 1, Abdulrahman Abdullah Aljadid 1, Faisal Mohammed Alosaimi 1, Yussef Falah Alharbi 1, Bedour Subhi AlAujan 1, Mohammed Abdullah Alzaher 1, Bodour Nasser Alsahli 1, Ali Khawaji Ali 1, Wedad Shilash Alanazi 1, Jehad Hassan Alshaikh 1, Brahim Madhour Alshammari 1, Abdulrahman Mohammed Abdulkarim Alsadun 1
This review highlights the design flexibility of FSEDs in promoting efficiency and satisfaction, whereas HBEDs emphasize acuity-based care through structured zoning and optimized clinical flow.
Abstract | Full Text |PDF (479 KB) | Open Access Article
The Evolution of Medicine and Medical Law: From Ancient Civilizations to Modern Uzbekistan
Mukhitdinova Firyuza Abdurashidovna 1*
This study discusses the intertwined development of medicine and medical law, highlighting Uzbekistan's contributions and modern reforms in healthcare.
Abstract | Full Text |PDF (119 KB) | Open Access Article
Abdulaziz Mohammed Almuhaylib 1*, Badr Sayyah Al-Anzi 1, Ahmed Ibrahim Al-Ahmad 1, Sultan Suleiman Issa Al-Harb 1, Sultan Mohammed Algfari 1, Nawaf Sakr Almutairi 1, Bader Talhab Al-Anzi 1, Abeer Ali Alyehya 1, Zaid Helal Alanaz 2, Mokhld Sanhat Alotaibi 2, Yousef Mansour Aloudah 2, Abdulrahman Munawir Alanazi 2, Rayid Mohammed Alanazi 2, Talal Fares Awadh Almutairi 2, Mohammed Farhan Aldhafiri 2, Mohammed Raja Alharithi 2, Eman Sulaiman A Aljuaid 2, Alaa saud Alanazi 2*
Paramedics can enhance immune health by promoting nutrition, detecting deficiencies, and collaborating with public health experts for better patient outcomes.
Abstract | Full Text |PDF (375 KB) | Open Access Article
Bibliometric Analysis of Social Media Marketing in Hospitals: Trends and Influences
Febby Rosidayani 1*, Qurratul Aini 2
This study provided insights into social media's impact on hospital marketing, highlighting key trends, influential authors, and future research opportunities.
Abstract | Full Text |PDF (715 KB) | Open Access Article
Analyzing Sharia Service Standards in Certified Hospitals for Optimal Healthcare Quality
Faris Amrullah 1*, Qurratul Aini 2
This systematic review showed research trends and collaboration in Islamic hospitals, enhancing healthcare quality through Sharia service standards.
Abstract | Full Text |PDF (820 KB) | Open Access Article
Ananda Haris 1* , Qurratul Aini 1
This study showed a comprehensive bibliometric analysis of EMR acceptance and adoption trends over a decade, emphasizing theoretical frameworks and global research patterns.
Abstract | Full Text |PDF (1 MB) | Open Access Article
Aini Muzayyana 1*, Qurratul Aini 1
Provides a comprehensive analysis of HBM research trends among healthcare workers, highlighting gaps and informing future research and policy.
Abstract | Full Text |PDF (908 KB) | Open Access Article
Implementation and Impact of Hospital Bylaws in Indonesian Healthcare: A Scoping Review
Zulfa Nadia Danasti 1*, Qurratul Aini 1
This review identifies factors influencing bylaw implementation, enhancing hospital governance and patient safety in Indonesian healthcare settings.
Abstract | Full Text |PDF (471 KB) | Open Access Article
Positive Coping and Community Resilience in Disaster Management for Flooding in Malaysia
Hana W. Jun Chen 1,*, Roy Rillera Marzo 2, Mila Nu Nu Htay 3, Sakina Ruhi 1,*, Sarah Mohd Zainal Abidin 1, Allistair Adam Nelson 1, Haryati Anuar 1, Jegathambigai Rameshwar Naidu 1, Irma Muslimin 4, Andi Salim 5
Recognizing the significance of coping mechanisms in fostering community resilience is essential for reducing the effects of flooding and enhancing health risks and disaster preparedness in Malaysia.
Abstract | Full Text |PDF (520 KB) | Open Access Article
Early Prevention Strategies for Childhood Obesity: A Path to Reducing Long-Term Health Risks
Nafel Sammah Alharbi 1*, Hanadi Naji Hajrasi 1, Saud Mohammed Al-Harbi 1, Ahmed Abdullah Sharkh Alsharekh 1, Sulaiman Al Bawardi 1, Nasser Suliman Al-Nasser 1, Suliman Alhoureny 1, Abdullah Altwejry 1, Salem Faraj M Alqahtani 1, Nawal Hlal salah Almotairi 1, Mariam Sabr Shafagh Alshameri 1, Nawal Ganai Mohammed Bahari 1, Alhanouf Zaid Munawer Almutairi 1, Yazeed Nasser Fawaz AlMousa 1, Saif Sultan Alsahli 1, Nuha Naif Alshammari 2, Saif Sultan Alsahli 1, Batoul Nasser Al-Qudum 1, Afaf Masoud Al-Balawi 1, Bunaydir Aali Almotairi 1*
This review provides the importance of early prevention strategies to combat childhood obesity and reduce long-term health risks.
Abstract | Full Text |PDF (501 KB) | Open Access Article
Mohammed Taresh Alshammari 1*, Bunaydir Aali almotairi 1, Reem Sultan Alshaibani 1, Bashair Maqbool Alharbi 1, Munirah Nassar Arabi 1, Maryam Helal Alanazi 1, Layla Aqeel Alanizi 1, Aljazi Awadh AlAni 1, Afnan Mohammed Al Dosari 1, Eman Ibrahim Alshaikh Ali 1, Khwlah Abdulaziz Alswaied 1, Mohammed Naif Al Mutairi 1, Abdulkarim Shunayn Safi Alanazi 1, Fahad Husayyan Al Enazi 1, Bander Nasser Alharbi 1
This study explores the complexities of multimorbidity, emphasizing patient-centered care and interventions to improve healthcare outcomes.
Abstract | Full Text |PDF (161 KB) | Open Access Article
Brain-Computer Interfaces Can Significantly Improve The Quality of Life for Aged People - A Review
Sanjay Kumar Mire 1, Deepak Kumar Sahu 2
A non-invasive Brain-Computer Interfaces (BCIs) and IoT-based Smart Home Technology can enhance memory, focus, and aged people's quality of life.
Abstract | Full Text |PDF (625 KB) | Open Access Article
Salmuhaylib, Abdulaziz Mohammed 1, Afnan Mohammed Bin Jabal 1, Naif Ruwaydhan Al Ruwaydhan 1, Ali Mutlaq Ali Alsubaie 1, Hamad Dafalh Alrakhimy 1, Abdulaziz Shayim Alsharari 1, Salman Ghazi Al-Faridi 1, Ali Jamal Alanazi 1, Abdulrahman Abdullah Alorf 1, Ahmed Turki Alotaibi 1, Abdulrahman Munawir Alanazi 1, Rayid Mohammed Alanazi 1, Yousef Mansour Aloudah 1, Moteb Roshaid Al-Shamari 1, Sultan Fares Alshamari 1, Zaid Helal Alanazi 1, Talal Fares Awadh Almutairi 1, Bassam Mohammed Al-Rashid 1*
This review identifies critical gaps and strategies to improve emergency care systems in post-conflict settings, enhancing healthcare delivery and outcomes.
Abstract | Full Text |PDF (276 KB) | Open Access Article
Abdulrahman Haif Aljish 1, Abdulrhman Mutab Almuteri 1, Nader Abdulhadi Abdullah Aljohani 1, Rashed Obaid Al-Harbi 1*, Mohammad Shabib Alharbi 1, Naif Abdulrahman Al-Azmi 1*, Talal Muteb Alharbi 1, Abdulalah Thabet Alharbi 1, Faleh Shaman Ayad Alharbi 1, Nader Mahli Mohammed Alharbi 1, Nasser Gaed Al-Subaie 1, Abdullah Alhumaidi Alharbi 1, Mohammed Rashed Aldhahri 1, Sanad Hamdan Al Shamri 1, Zaher Mohammed Alshehri 1, Rayan Ali Sulaiman 1, Abdullah Essa Alessa 1
This study highlights the emotional challenges paramedics faced and the resources crucial for supporting their mental well-being during COVID-19.
Abstract | Full Text |PDF (1 MB) | Open Access Article
Current Perspective on Pesticides: Their Classification, Behaviour, Potential Use and Toxic Effects
Adil Ahamad1*, Javed Ahamad2, Mohd. Javed Naim2
Monitoring the use of pesticide and analyzing their acceptable levels for human health.
Abstract | Full Text |PDF (442 KB) | Open Access Article
Knowledge and Self-Management Practice Among Diabetic Patients from the Urban Areas in Bangladesh
Md. Jubayer Hossain1, Syeda Tasneem Towhid1,2* , Sumona Akter1 , Muhibullah Shahjahan1, Tilottoma Roy1, Bithi Akter1, Tanjum Ahmed Nodee1
Abstract | Full Text |PDF (481 KB) | Open Access Article
Impact of Legalized Recreational Cannabis on Emergency Department Presentations: A Systematic Review
Abdullaziz Fahad Abdullah Alwanais 1, khalid saad mobarak alharbi1, Awad Jzzaa alshammari 1, Naif Ali Shalwah Alalawi 1, Mohammed Ahmed Ibrahim Alshaikhi 1, Ali Saleh Alghamdi 1, Meshal Saleh D Alharbi 1
Recreational cannabis legalization increases global emergency department burden, highlighting urgent need for targeted regulations, prevention strategies, and equitable public health interventions.
Abstract | Full Text |PDF (382 KB) | Open Access Article
Sharif Owaidh T. Almutairi 1*, Nujud Abdulrahman Almousa 1, Amal Hajjan Alanzi 1, Adel Dakhel D. Alharbi 1, Muteb Abdulaziz Abdullah Al Askar 1, Saeed Ali Aljarman Alshrany 1, Abdullah Mukhlef J. Alanazi 1, Abdullah Ghazi Alsuqmi Alruwaili 1
This study analyzes Workforce Well-being 2.0, which transforms adversity into growth by integrating burnout prevention with post-traumatic growth to strengthen resilience and boost organizational productivity.
Abstract | Full Text |PDF (639 KB) | Open Access Article
Systematic Review
Public Health & Epidemiology
Sree Shib Shankar Devnath Debu1, Israt Jahan Eti2, Subrata Sarker Shubho3, Md. Manjurul Islam4, Mamata Mostari5, Umme Sadia6
This study is significant as it highlights the effectiveness of smart nutrition and active living in managing hypertension, promoting sustainable, non-pharmacological interventions for better cardiovascular health.
Abstract | Full Text |PDF (917 KB) | Open Access Article
The peer-reviewed and edited version of record published online before inclusion in an issue
These articles have been peer reviewed and accepted for publication. They are still in production and have not been edited, so may differ from the final published form.
The Most Read ranking is based on the number of downloads in the last 60 days from papers published on the Journal of Angiotherapy within the last 12 months. Usage statistics are updated daily.
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Revolutionizing Healthcare: The Role of Artificial Intelligence in Drug Discovery and Delivery
This study shows how AI can change the way drugs are made and delivered, making healthcare faster, more personalized, and cheaper.
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TGF-β1 as a Molecular Target and Vitamin D Interaction in Diabetic Nephropathy: A Bio-clinical Correlation Study
Clarifies the potential role of vitamin D and kidney dysfunction in diabetic nephropathy through clinical and molecular analysis.
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RETRACTED ARTICLE: Predicting Parkinson’s Disease Progression Using Statistical And Neural Mixed Effects Models: Comparative Study On Longitudinal Biomarkers
This study demonstrates interpretable, robust modeling for Parkinson’s telemonitoring, guiding reliable disease progression prediction under small-sample longitudinal data constraints.
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Cardiometabolic Impact of Vitamin D Deficiency as a Determinant of Coronary Artery Disease: A Review
The results demonstrate a strong link between vitamin D deficiency and an increased risk of coronary heart disease in adults.
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Deep Mapping of Neuro-phenotypes Using AI-Enhanced MRI: A Contrast-Based Multiplanar Analysis
AI-driven contrast mapping enhances voxel-level T2-MRI brain analysis, revealing phenotypic variations crucial for early diagnosis and neurodevelopmental profiling
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Potential Therapeutic Targets Associated with the Autoimmune Response in Crohn's Disease
This review elucidates autoimmune mechanisms in Crohn’s disease, highlighting emerging molecular targets to advance precision immunotherapy and improve patient outcomes.
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An Integrated AI-Driven Framework for Maternal Resource Intelligence Shortages Across U.S. Hospital
Integrating predictive analytics, reinforcement learning, and causal inference improves maternal outcomes by aligning risk prediction with real-time, equity-aware resource allocation decisions.
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Serum Uric Acid Reduction Following Use of Canssu5®, a Standardized Orthosiphon stamineus Extract, in Adults with Hyperuricemia: A Retrospective Case Study
This study provides preliminary clinical evidence that standardized Orthosiphon stamineus extract may meaningfully reduce serum uric acid in hyperuricemic adults.
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Comprehensive Review of Foundation Toxicity Models Integrating In Vivo, In Vitro, and Chemical Knowledge for Unified Risk Prediction
Bridges experimental and computational toxicology to enable predictive, human-relevant risk assessment frameworks for safer and faster chemical evaluation
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Integrative Molecular and Microbial Mechanisms Linking Liver Fibrosis, Cancer Biology, and Host-Microbe Interactions
This study integrates biomedical and ecological research, revealing shared biological mechanisms that inform therapeutic innovation, sustainable agriculture, and systems-level understanding of complex biological interactions.
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Dietary Bioactive Compounds in Cancer and Cardiovascular Health: A Systematic Review of Methylxanthines, Polyphenols, and Flavonoids
This study demonstrates that dietary bioactive compounds play a significant role in reducing the risk of chronic diseases, improving cardiovascular health, and offering protective effects against certain types of cancer.
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Therapeutic Angiogenesis: From Single-Factor Failures to Precision Vascular Regeneration
Multimodal, precision-guided angiogenic therapies—gene, cell, extracellular vesicle, and biomaterial-based—offer transformative potential for treating ischemic diseases where revascularization remains unfeasible.
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Epigenetic Clocks and Biological Ageing: From Biomarker to Intervention Target
Epigenetic clocks convert DNA methylation into a modifiable biomarker, repositioning ageing as a treatable clinical target.
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Mapping the Invisible Architecture of Disease: Spatial Multi-Omics Technologies, Computational Integration, and the Path Toward Clinical Translation
Spatial multi-omics repositions tissue context as a first-class clinical variable, but equitable, standardized translation remains unfinished business.
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Why Artificial Intelligence Models for Antimicrobial Resistance Still Fail at the Bedside: A Review of Validation, Explainability, and Equity Gaps
Explains why highly accurate AI resistance models fail clinically, and outlines concrete validation, equity, and deployment fixes.
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Single-Cell and Spatial Transcriptomics in Precision Diagnostics: A Roadmap for Clinical Adoption
Spatial transcriptomics reveals disease architecture at cellular resolution, but cost, FFPE limits, and complexity keep it from routine clinical diagnostics.
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From Days to Hours: Artificial Intelligence in Antimicrobial Resistance Diagnostics and Drug Discovery, and Why No Tool Has Yet Reached the Clinic
AI compresses AMR diagnosis and discovery timelines dramatically, yet no tool has reached regulatory clearance — validation and trust, not algorithms, remain the bottleneck.
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The Gut–Brain–Immune Axis in Chronic Disease: Mechanisms and Therapeutic Opportunities — A Narrative Synthesis
This review reframes chronic neurodegenerative and autoimmune disease through a reproducible, microbiome-centered mechanistic and therapeutic lens.
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Multichemical Endocrine Disruption of Thyroid and Sex Hormone Signaling Drives Early-Life Neurodevelopmental Impairments
This study highlights how prenatal endocrine disruptor exposure impairs neurodevelopment, emphasizing mixture effects, biological mechanisms, and urgent regulatory intervention needs.
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Extracellular Vesicles as Diagnostic and Therapeutic Tools: Closing the Translational Gap
Extracellular vesicles promise cell-free precision diagnostics and therapeutics, but standardization, scalability, and regulatory gaps still block routine clinical adoption.
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Senescent Cell Heterogeneity and Precision Clearance Strategies: From Molecular Mechanism to Clinical Translation
Mapping senescent-cell heterogeneity to precision senotherapies could transform multimorbid, age-related disease treatment safely
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Obesity Pharmacotherapy in the GLP-1 Era: Efficacy, Equity, and the Long-Term Unknowns of Incretin-Based Care
Bariatric-level pharmacotherapy now exists, yet muscle loss, rebound, cost, and pediatric uncertainty still limit its real-world promise.
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Organoid-on-Chip Platforms as Predictive Models of Human Disease: Promise and Pitfalls
Organoid-on-chip systems merge biological fidelity with engineering precision, offering AI-augmented, human-relevant platforms positioned to reshape preclinical drug development.
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Mitochondrial Transfer Between Cells: Physiological Roles and Therapeutic Potential
Intercellular mitochondrial transfer sustains tissue bioenergetics and immunity, offering a transformative, biologically grounded therapeutic strategy for degenerative and ischemic disease.
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Tissue-Resident Memory T Cells in Health and Disease: Emerging Regulators of Immunity
Tissue-resident memory T cells permanently guard peripheral organs, but their dysregulation drives chronic autoimmune disease, making them a precise emerging therapeutic target.
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Multimorbidity in Ageing Populations: Redefining Clinical Guidelines for Combined Disease Management
Frailty-based, mechanism-anchored prescribing frameworks could replace single-disease guidelines that quietly harm complex older patients.
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Long COVID as a Network Disorder: Mechanisms, Biomarkers, and the Path Toward Mechanism-Anchored Clinical Stratification
Reframing Long COVID as a biologically stratifiable network disorder could finally make targeted, effective treatment trials possible.
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Emerging CRISPR-Cas, Antibody, and Nanomedicine Strategies Against Antimicrobial Resistance in Critical Care
AMR is outpacing critical-care antibiotics; precision genomic, antibody, peptide, and nanozyme strategies may restore therapeutic options.
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Integrating Genomics, Transcriptomics, and Organoid-Based Drug Testing for Precision Cancer Care
Integrating transcriptomic, epigenetic, and functional organoid data with genomics may finally close oncology’s persistent gap between diagnosis and matched treatment.
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Digital Biomarkers and Wearable Bioelectronics Across Neurological, Cardiopulmonary, and Mental Health Conditions: Clinical Evidence and Barriers to Adoption
Wearable digital biomarkers show strong clinical validity but require standardized validation, interoperable data systems, and equitable design before routine adoption.
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Modifiable Triggers and Autoimmune Disease Flares: A Mechanistic and Clinical Synthesis of Molecular Mimicry, Barrier Disruption, and Neuroendocrine-Microbial Crosstalk
Environmental exposures converge with genetic risk to trigger autoimmune flares, guiding precision prevention beyond genetics alone.
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Artificial Intelligence in Precision Cardiovascular Medicine: Risk Prediction, Digital Twins, and Explainability
Artificial-intelligence risk models and digital twins could shift cardiology from reactive treatment toward proactive, individualized prevention — if bias, validation, and trust gaps are honestly addressed.
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Moving Beyond the Double-Strand Break Through CRISPR-Based Epigenome Editing for Specificity-Driven Sickle Cell Disease Therapy
Epigenome editing may silence sickle-globin defects without DNA cleavage, offering a safer, durable alternative to nuclease-based gene therapy.
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Non-Coding RNA Networks in Pancreatic Ductal Adenocarcinoma: An Expanding Regulatory Landscape from the ceRNA TRIAD to Exosomal Immune Evasion and Ferroptosis Escape
Non-coding RNA networks orchestrate pancreatic cancer progression, immune evasion, and chemoresistance, revealing druggable nodes for precision therapy.
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Liquid–Liquid Phase Separation as a Unifying Biophysical Driver of Proteinopathy in ALS and Frontotemporal Dementia: Mechanisms, Molecular Grammar, and Therapeutic Vulnerabilities
Mapping how ALS/FTD proteins phase-separate and solidify reveals shared biophysical vulnerabilities that could be therapeutically exploited across the disease spectrum.
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RNA Modifications Reprogram the Epitranscriptome to Drive Hepatocellular Carcinoma Progression
RNA modifications reprogram liver-cancer transcripts to drive growth, immune escape, and drug resistance—offering new biomarkers and druggable targets.
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Protein Language Models for Predicting BRCA1/BRCA2 Variant Pathogenicity: A Computational Bridge Toward Precision Oncology
Protein language models can resolve uncertain BRCA variants rapidly, potentially widening equitable access to PARP-inhibitor therapy worldwide.
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Chromatin Architecture Disruption Drives Transcriptional Dysregulation and Reveals Therapeutic Vulnerabilities in Acute Myeloid Leukaemia
STAG2/cohesin loss and oncofusion proteins collapse 3D chromatin loops in AML, silencing differentiation genes while revealing druggable, reversible epigenetic vulnerabilities.
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Cellular Senescence as a Pathogenic Hub Driving Mechanistic Networks and Reversal Strategies in Idiopathic Pulmonary Fibrosis
Cellular senescence organizes IPF pathogenesis across cell types, positioning senotherapeutics and regenerative cell therapy as biologically grounded strategies for reversing, not merely slowing, fibrosis.
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Integrating Molecular Modeling and Kinetic Insights to Decipher Structure–Activity Relationship Trends in Small-Molecule Inhibitors of α-Glycosidases
This study clarifies structural features driving potent α-glycosidase inhibition, enabling rational design of selective therapeutics through integrated computational–experimental mechanistic insights.