Journal of Angiotherapy

Labisia pumila extracts based products will require robust studies to be conducted utilizing larger patient numbers and over extended periods of time to rule out any potential toxic effects.

Metal salts and base rosmarinates demonstrated potent anti-GBM efficacy as IL17A inhibitor with minimal toxicity.   

The molecular mechanism of iNOS that leads to CVD is comprehensively summarized in this review so as to aid in drug discovery strategies for the treatment of CVD.

Anogeissus leiocarpus is a traditional medicinal plant, used to treat diarrhea, fever, coughs, rheumatism, leprosy, wounds and skin diseases and psoriasis. This study was aimed to investigate the antiangiogenic and cytotoxic effects of six extracts from Anogeissus leiocarpus (leaves and bark).

This study provides insight to EDHF-mediated vasomotor response, as well as various eye disorders caused by dysfunctional retinal arteries, like central retinal artery occlusion.

Angiogenesis is an important physiological process by which new blood vessels form from pre-existing vessels. Hence, targeting angiogenesis may have a potential therapeutic value in treating or managing pathogen infection.

Crinum asiaticum is used traditionally to treat inflammations and tumours. The aim of this work is to ascertain the scientific viability of its use in traditional medicine as an anti-tumour (potential anti-cancer) agent.

The role of angiogenesis in tumor development and operating this very particular switch in controlling tumor.    

SLOS vesicles can be considered for effective dermal therapeutic agent for the treatment of skin cancer.

In the current study, role of synthesized chemical pharmacores like Humulus lupulus, Hypericum perforatum, Panax ginseng, Coptis chinensis and Rheum palmatum (Varinska et al., 2010) as anti-angiogenesis has been compiled. 

Sophorolipids are of growing commercial interest because they can be easily produced in extreme1y high yields from cheap raw materials, such as vegetable oils, n-alkanes and industrial waste products.

C5OSEW5050ESA OS strongly curbs variety of angiogenesis modulators in vitro, ex vivo and in vivo.

Advance research into developing experimental model to study uterine fibroid will aid in better understanding this disease.

Targeted ultrasound appears practical for the longitudinal molecular profiling of tumor angiogenesis and for the sensitive evaluation of therapy effects in vivo.  

U. grandiflora could be a new source of chemotherapeutic for breast cancer.

obesity has a strong association with several metabolic disorders such as the type 2 diabetes and cardiovascular disease, which affect over 50% of an adult population

Cancer develops following a number of genetic mutations that cause functional alterations in oncogenes, tumor-suppressor genes and microRNA genes.

Reviews current literature on use of phytochemicals in prevention and therapy of ovarian cancer including mechanism of action.

Although findings about the biological role of angiogenesis factors in CKD are relatively limited, therapeutic effects have been reported for angiogenesis factors in experimental diabetic nephropathy models. 

Ox in combination Cur demonstrated very high synergism against HT-29 and Caco-2 cell lines.

Small molecules that can be programmed to mimic transcription factors could be useful tools in biology and potentially in human medicine as they could bind a large repertoire of DNA sequences in the human genome.

Oral treatment with encapsulated plant extract Ficus deltoidea and Gynocthodes sublanceolata did not appear adverse side effect and it is safe to use for therapeutic purposes.

Piperine can be considered a potential phototherapeutic drug for the treatment of prostate cancer.

Development of anti-inflammatory herbal drug.

The results of this study provide scientific evaluation of antibacterial activity and hepatoprotective effect of Rauwolfia serpentina which will be useful to researchers investigating the compounds with this potential and encouraging the development of new findings in this field.

The study represents the evaluation of resistin levels in gingival crevicular fluid in diabetic patients with and without chronic periodontitis.

The study significance focuses on how hyperglycemia relates periodontitis and diabetes mellitus.

The study finds out In vitro anti-inflammatory activity of Magnifera indica peels using protein denaturation assay.

The present study has an impact on overcoming the inflammation problem, which can lead to various types of chronic inflammatory diseases, using the artocarpin  & artocarpin-rich Artocarpus heterophyllus extract. The primary significance of this research is the achievement of preparation of a natural anti-inflammatory and analgesic agent using a green chemistry, which contributes to combat inflammation and analgesia. Furthermore, this method is practically used for industrial commercialization.    

The purpose of this review is to provide information on host response and genetic variations in major apical periodontitis signaling pathways.

Salivary diagnostics is an emerging field along with the application of genomics aid in the early detection of different diseases. These genomic alphabets of saliva may serve as a timely, cost-effective, non-invasive diagnostic medium. This review aims to discuss the genetic biomarkers of saliva in various diseases.

Active treatment of SLE is required to prevent the progression of systemic involvement.

In the present study, we investigated the role of leptin in the pathogenesis of atherosclerosis by measuring its levels in atherosclerosis subjects and analyzing its correlation to anthropometric variables such as waist to hip ratio, body mass index, biochemical parameters such as lipids and glucose. Leptin levels correlate to serum glucose, triglycerides, waist to hip ratio, body mass index, and blood pressure in atherosclerosis subjects with increased body mass index. Our results show that leptin influences the lipid profile to induce the pathogenesis of atherosclerosis.

The study implements the history of the condition in the context of its contemporary understanding is reviewed in this article and recommendations made in how we view pacing in the context of this intriguingly opaque condition.

Several cases of scurvy secondary to diet limitations have been reported in the literature. Here we present a six-year-old boy who presented with rash, later developed pain in both lower extremities. After evaluation revealed vitamin C deficiency, he was admitted into an intensive day treatment feeding program. A feeding assessment found he had life-long problems with eating and had a diet that never exceeded ten foods. Across the course of treatment, he learned to eat 29 new foods. At eight-months follow up his body mass index had increased.  

Further detailed evaluation of any uncontrolled asthma despite proper treatment is required to evaluate the cause and to provide appropriate treatment.

This review discusses the measurement of albuminuria and summarizes the current literature on the association between albuminuria and adverse cardiovascular and renal outcomes in type 2 diabetes and hypertension.

Important in finding apprehension related to noise in dental offices among children.

Camphor poisoning should be considered as a cause of seizure in otherwise healthy children and parents should be asked regarding possible ingestion of camphor products in the preceding few hours.

The study is the Rhizomelic chondrodysplasia punctata  (RCDP), a rare peroxisomal disorders.

The treatment of choice is the new penicillin III plus cefotaxime sodium, ceftriaxone, cefuroxime sodium; for MRSA infection, vancomycin or selection of intravenous clindamycin drug improved clinical symptoms, inflammatory markers returned to normal in 3 - 6 weeks. Joint cavity decompression, drainage of pus, and supportive therapy are essential. Osteomyelitis can affect the growth of long bones, thus affecting the length and can generate angular deformity.

This study has critically evaluated the utility of GGT as a diagnostic marker of metabolic syndrome, with good inferences. An elevated level of GGT was found to be associated with metabolic syndrome and is a strong predictor of cardiovascular risk.

The patient’s acute coronary syndrome likely resulted from the combination of endothelial disruption from coronary artery dissection in the context of chest trauma, compounded by acute thrombosis, coronary occlusion, and subsequent myocardial infarction due to heparin-induced thrombocytopenia.

We report a case of GBS in a chronically HIV-infected patient in association with a primary B19V infection.

It is worth to see thyroid function in known CKD patients and appropriate THRT to correct reversible renal impairment due to hypothyroid.

Careful diagnosis and timely intervention of the paediatric eye leads to the most promising outcome and gives these children a long morbidity-free life.

The present study explored an awareness on the preventive aspect on the root cause for diabetes in relevant to essential fatty acids rich food and its source, to change in the lifestyle, apart from screening, management, and treatment of diabetes.

Several case reports show asymptomatic cardiovascular involvement in severe leptospirosis. follow up needed in all patients with uncomplicated leptospirosis and cardiac vascular involvement evaluation with an ECG and cardiac enzymes to avoid complications to the patient.

Patient presents with sudden onset of chest pain with electrocardiography showing ST segment elevation, it is usually difficult to differentiate between myocardial ischemia and AAD. Here, we present a patient with chest pain with initial suspicion of a myocardial infarction, which was AAD.

This study shows better Harris hip score, range of motion and less pain. Hedbeck21 preferred bipolar hemiarthroplasty over unipolar because of less acetabular erosion in long term and hence better functional outcome, similar to our study.

The diagnosis of FAP is based on the detection of more than 100 adenomatous Colon polyps. We had a case of FAP in a 37-year-old man with history of abdominal pain and bleeding per rectum for 6 months.

We report a case of a male patient aged 20 years who presented to us with anal bleed, pain and distension of abdomen, and severe breathlessness following a self-thrusting of a vacuum blower pipe into the anal orifice for sexual stimulation.

NLR is a valuable predictor of AECOPD and mortality. Furthermore, it correlates well, and in some studies is even more accurate, than other traditional inflammatory indexes (WBC counts alone) or more complex and expensive markers (CRP and calprotectin).

The incidence of SSI was high. Age, gender, BMI, Comorbidities like Anemia, Hypertension and Diabetes mellitus, Blood transfusion, preoperative waiting, and prophylactic antibiotic usage were risk factors for SSI. However, only gender, extreme BMI, Diabetes mellitus, and Blood transfusion were significant predictors for SSIs on multivariable analysis.

This article discusses the major changes in surgical practice, which need to be brought in.

The prevalence of varying forms of AKI in patients suffering from dengue requires early diagnosis to plan appropriate management and prevent life-threatening complications.

We report a 32-year-old male who presented with features of haemolytic anemia and later diagnosed as a case of SLE.

The prognostic value of NLR for COPD remains controversial. The NLR was an effective predictor for respiratory hospitalization, while another study showed the NLR had no signi?cant association with COPD exacerbation.

The Co-infection of both CMV and Scrub Typhus is uncommon. So a comprehensive evaluation for tropical infections in an immunosuppressed patient is necessary.

We report a case of 42-year-old male who is a known case of tuberous sclerosis and presented with swelling in the axilla. Excision biopsy of the axillary swelling and ugi endoscopic biopsy showed poorly cohesive adenocarcinoma of the stomach.

The Staphylococcal Scalded Skin Syndrome especially affects infants and small children. SSSS is usually preceded by sore throat or conjunctivitis.

Surgery for benign mature teratoma requires Unilateral ovariectomy and follow-up. Pathological examination must differentiate between mature and immature teratoma. Immature teratomas are potentially malignant, so the patient may require Chemotherapy (BEP regimen) and Radiotherapy.

The treatment strategy involves general measures to correct the underlying cause of PRES. An early etiologic diagnosis helps the cause of PRES to be promptly corrected. Blood pressure management, removal of cancer chemotherapy or immunosuppressive agents, dialysis, or other treatments may be appropriate

Development of therapeutics for the treatment of hepatotoxicity and oxidative stress  induced by ATDs

Environmental and physiological angiogenesis and its impact emergence in CVD management 

In this review, we summarize reported effects of some phytoestrogens that bind directly to tubulin at various binding site and disrupt the microtubule dynamics, either by promoting microtubule polymerization or enhancing microtubule depolymerization.